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315701por Saito, Makoto, Carrara, Verena I., Gilder, Mary Ellen, Min, Aung Myat, Tun, Nay Win, Pimanpanarak, Mupawjay, Viladpai-nguen, Jacher, Paw, Moo Kho, Haohankhunnatham, Warat, Konghahong, Kamonchanok, Phyo, Aung Pyae, Chu, Cindy, Turner, Claudia, Lee, Sue J., Duanguppama, Jureeporn, Imwong, Mallika, Bancone, Germana, Proux, Stephane, Singhasivanon, Pratap, White, Nicholas J., Nosten, François, McGready, Rose“…RESULTS: Between February 2010 and August 2016, 511 pregnant women with malaria (353 P. vivax, 142 P. falciparum, 15 co-infections, 1 Plasmodium malariae) were randomized to either DP (n=170), ASMQ (n=169) or AL(+) (n=172) treatments. Successful malaria elimination efforts in the region resulted in premature termination of the trial. …”
Publicado 2021
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315702por Gelanew, Tesfaye, Seyoum, Berhanu, Mulu, Andargachew, Mihret, Adane, Abebe, Markos, Wassie, Liya, Gelaw, Baye, Sorsa, Abebe, Merid, Yared, Muchie, Yilkal, Teklemariam, Zelalem, Tesfaye, Bezalem, Osman, Mahlet, Jebessa, Gutema, Atinafu, Abay, Hailu, Tsegaye, Habte, Antenehe, Kenea, Dagaga, Gadisa, Anteneh, Admasu, Desalegn, Tesfaye, Emnet, Bates, Timothy A., Bulcha, Jote Tafese, Tschopp, Rea, Tsehay, Dareskedar, Mullholand, Kim, Howe, Rawleigh, Genetu, Abebe, Tafesse, Fikadu G., Abdissa, Alemseged“…Descriptive statistics and bivariate and multivariate logistic regression were used to determine the overall and post-stratified seroprevalence and the association between seropositivity and potential risk factors. RESULTS: Our successfully developed in-house assay sensitivity was 100% in serum samples collected 2- weeks after the first onset of symptoms whereas its specificity in pre-COVID-19 pandemic sera was 97.7%. …”
Publicado 2022
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315703por Kerckhove, Nicolas, Delage, Noémie, Cambier, Sébastien, Cantagrel, Nathalie, Serra, Eric, Marcaillou, Fabienne, Maindet, Caroline, Picard, Pascale, Martiné, Gaelle, Deleens, Rodrigue, Trouvin, Anne-Priscille, Fourel, Lauriane, Espagne-Dubreuilh, Gaelle, Douay, Ludovic, Foulon, Stéphane, Dufraisse, Bénédicte, Gov, Christian, Viel, Eric, Jedryka, François, Pouplin, Sophie, Lestrade, Cécile, Combe, Emmanuel, Perrot, Serge, Perocheau, Dominique, De Brisson, Valentine, Vergne-Salle, Pascale, Mertens, Patrick, Pereira, Bruno, Djiberou Mahamadou, Abdoul Jalil, Antoine, Violaine, Corteval, Alice, Eschalier, Alain, Dualé, Christian, Attal, Nadine, Authier, Nicolas“…Better characterization of patients could help to identify the predictors of successful treatments, and thus, guide physicians in the initial choice of treatment and in the follow-up of their patients. …”
Publicado 2022
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315704por Akpan, Godwin Ubong, Bello, Isah Mohammed, Touray, Kebba, Ngofa, Reuben, Oyaole, Daniel Rasheed, Maleghemi, Sylvester, Babona, Marie, Chikwanda, Chanda, Poy, Alain, Mboussou, Franck, Ogundiran, Opeayo, Impouma, Benido, Mihigo, Richard, Yao, Nda Konan Michel, Ticha, Johnson Muluh, Tuma, Jude, A Mohamed, Hani Farouk, Kanmodi, Kehinde, Ejiofor, Nonso Ephraim, Kipterer, John Kapoi, Manengu, Casimir, Kasolo, Francis, Seaman, Vincent, Mkanda, Pascal“…RESULTS: The contact tracing app and platform were piloted between April and June 2020; they were then put to use in Zimbabwe, Benin, Cameroon, Uganda, Nigeria, and South Sudan, and their use has generated some palpable successes with respect to COVID-19 surveillance. However, the COVID-19 health facility–based surveillance app has been used more extensively, as it has been used in 27 countries in the region. …”
Publicado 2022
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315705por Münzker, Julia, Haase, Nadine, Till, Andreas, Sucher, Robert, Haange, Sven-Bastiaan, Nemetschke, Linda, Gnad, Thorsten, Jäger, Elisabeth, Chen, Jiesi, Riede, Sjaak J., Chakaroun, Rima, Massier, Lucas, Kovacs, Peter, Ost, Mario, Rolle-Kampczyk, Ulrike, Jehmlich, Nico, Weiner, Juliane, Heiker, John T., Klöting, Nora, Seeger, Gudrun, Morawski, Markus, Keitel, Verena, Pfeifer, Alexander, von Bergen, Martin, Heeren, Joerg, Krügel, Ute, Fenske, Wiebke K.“…CONCLUSION: Our results establish the role of the gut microbiome in the weight loss and metabolic success of gastric bypass surgery. We here identify a signaling cascade that entails altered bile acid receptor signaling resulting from a collective, hitherto undescribed change in the metabolic activity of a cluster of bacteria, thereby readjusting energy imbalance and metabolic disease in the obese host. …”
Publicado 2022
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315706por Gómez-Martínez, Carlos, Babio, Nancy, Júlvez, Jordi, Nishi, Stephanie K., Fernández-Aranda, Fernando, Martínez-González, Miguel Ángel, Cuenca-Royo, Aida, Fernández, Rebeca, Jiménez-Murcia, Susana, de la Torre, Rafael, Pintó, Xavier, Bloemendaal, Mirjam, Fitó, Montse, Corella, Dolores, Arias, Alejandro, Salas-Salvadó, Jordi“…Furthermore, nutritional intervention programs should consider impulsivity as a relevant factor for the intervention success. TRIAL REGISTRATION: Name of registry: Effect of an energy-restricted Mediterranean diet, physical activity and behavioral intervention on the primary prevention of cardiovascular disease. …”
Publicado 2022
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315707por Anmella, Gerard, Sanabra, Miriam, Primé-Tous, Mireia, Segú, Xavier, Cavero, Myriam, Morilla, Ivette, Grande, Iria, Ruiz, Victoria, Mas, Ariadna, Martín-Villalba, Inés, Caballo, Alejandro, Esteva, Julia-Parisad, Rodríguez-Rey, Arturo, Piazza, Flavia, Valdesoiro, Francisco José, Rodriguez-Torrella, Claudia, Espinosa, Marta, Virgili, Giulia, Sorroche, Carlota, Ruiz, Alicia, Solanes, Aleix, Radua, Joaquim, Also, María Antonieta, Sant, Elisenda, Murgui, Sandra, Sans-Corrales, Mireia, H Young, Allan, Vicens, Victor, Blanch, Jordi, Caballeria, Elsa, López-Pelayo, Hugo, López, Clara, Olivé, Victoria, Pujol, Laura, Quesada, Sebastiana, Solé, Brisa, Torrent, Carla, Martínez-Aran, Anabel, Guarch, Joana, Navinés, Ricard, Murru, Andrea, Fico, Giovanna, de Prisco, Michele, Oliva, Vicenzo, Amoretti, Silvia, Pio-Carrino, Casimiro, Fernández-Canseco, María, Villegas, Marta, Vieta, Eduard, Hidalgo-Mazzei, Diego“…Furthermore, 9% (3/34) of patients activated the suicide alert, and the research team promptly intervened with successful outcomes. Vickybot showed high subjective UEI (acceptability, usability, and satisfaction), but low objective UEI (completion, adherence, compliance, and engagement). …”
Publicado 2023
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315708por Gustavsson, Tobias, Metzendorf, Nicole G., Wik, Elin, Roshanbin, Sahar, Julku, Ulrika, Chourlia, Aikaterini, Nilsson, Per, Andersson, Ken G., Laudon, Hanna, Hultqvist, Greta, Syvänen, Stina, Sehlin, Dag“…RESULTS: Neither RmAb158-scFv8D3 nor RmAb158 reduced soluble Aβ protofibrils or insoluble Aβ1-42 after a single injection treatment. After three successive injections, Aβ1-42 was reduced in mice treated with RmAb158, with a similar trend in RmAb158-scFv8D3-treated mice. …”
Publicado 2023
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315709por Osuagwu, Uchechukwu L., Ocansey, Stephen, Ndep, Antor O., Kyeremeh, Sylvester, Ovenseri-Ogbomo, Godwin, Ekpenyong, Bernadine N., Agho, Kingsley E., Ekure, Edgar, Mashige, Khathutshelo Percy, Ogbuehi, Kelechi C., Rasengane, Tuwani, Nkansah, Nana Darkoah, Naidoo, Kovin Shunmugan“…PURPOSE: Knowledge, positive attitude and good preventive practices are keys to successful myopia control, but information on these is lacking in Africa. …”
Publicado 2023
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315710por Chen, Xi, Liu, Xin, Li, Qian-hui, Lu, Bing-feng, Xie, Bu-min, Ji, Yu-meng, Zhao, Yang“…Next, we enrolled 8 cases of high-risk and high-risk EC patients according to EMSO-ESGO-ESTRO guidelines and successfully constructed EC-PDOs. ASOs targeting SNORD14E inhibited the EC-PDO growth. …”
Publicado 2023
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315711por She, Chunhua, Wu, Chao, Guo, Weihua, Xie, Yongjie, Li, Shouyi, Liu, Weishuai, Xu, Chao, Li, Hui, Cao, Pei, Yang, Yanfang, Wang, Xiuchao, Chang, Antao, Feng, Yukuan, Hao, Jihui“…We constructed the stably expressing cell lines with shRUNX1 and RUNX1, and successfully established GEM-resistant cell line. The role of RUNX1 in GEM resistance was determined by CCK8 assay, plate colony formation assay and apoptosis analysis in vitro and in vivo. …”
Publicado 2023
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315712por Duri, Kerina, Munjoma, Privilege Tendai, Mataramvura, Hope, Mazhandu, Arthur John, Chandiwana, Panashe, Marere, Tarisai, Gumbo, Felicity Zvanyadza, Mazengera, Lovemore Ronald“…No HBs-antibodies were detected in 23.3% of HBsAg-exposed infants at two years despite having successfully completed the HBV vaccination schedule. …”
Publicado 2023
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315713por Kondili, Loreta A., Gaeta, Giovanni Battista, Brunetto, Maurizia Rossana, Di Leo, Alfredo, Iannone, Andrea, Santantonio, Teresa Antonia, Giammario, Adele, Raimondo, Giovanni, Filomia, Roberto, Coppola, Carmine, Amoruso, Daniela Caterina, Blanc, Pierluigi, Del Pin, Barbara, Chemello, Liliana, Cavalletto, Luisa, Morisco, Filomena, Donnarumma, Laura, Rumi, Maria Grazia, Gasbarrini, Antonio, Siciliano, Massimo, Massari, Marco, Corsini, Romina, Coco, Barbara, Madonia, Salvatore, Cannizzaro, Marco, Zignego, Anna Linda, Monti, Monica, Russo, Francesco Paolo, Zanetto, Alberto, Persico, Marcello, Masarone, Mario, Villa, Erica, Bernabucci, Veronica, Taliani, Gloria, Biliotti, Elisa, Chessa, Luchino, Pasetto, Maria Cristina, Andreone, Pietro, Margotti, Marzia, Brancaccio, Giuseppina, Ieluzzi, Donatella, Borgia, Guglielmo, Zappulo, Emanuela, Calvaruso, Vincenza, Petta, Salvatore, Falzano, Loredana, Quaranta, Maria Giovanna, Weimer, Liliana Elena, Rosato, Stefano, Vella, Stefano, Giannini, Edoardo Giovanni“…Interim findings showed that worsening of liver function after failure, in terms of Child Pugh class deterioration, was improved by successful retreatment in about one third of retreated patients within a short follow-up period; however, in some advanced liver disease patients, clinical outcomes (Child Pugh class, HCC development, liver failure and death) were independent of viral eradication.…”
Publicado 2017
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315714por AshaRani, PV, Jue Hua, Lau, Roystonn, Kumarasan, Siva Kumar, Fiona Devi, Peizhi, Wang, Ying Jie, Soo, Shafie, Saleha, Chang, Sherilyn, Jeyagurunathan, Anitha, Boon Yiang, Chua, Abdin, Edimansyah, Ajit Vaingankar, Janhavi, Sum, Chee Fang, Lee, Eng Sing, Chong, Siow Ann, Subramaniam, Mythily“…BACKGROUND: Diabetes management is a growing health care challenge worldwide. eHealth can revolutionize diabetes care, the success of which depends on end user acceptance. OBJECTIVE: This study aims to understand the readiness and acceptance of eHealth services for diabetes care among the general population, perceived advantages and disadvantages of eHealth, and factors associated with eHealth readiness and acceptance in a multiethnic Asian country. …”
Publicado 2021
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315715“…Two challenges exist in the grapevine research field: (i) the lack of a rapid, user-friendly and effective RNA isolation protocol for mature dark-skinned berries and, (ii) the lack of validated reference genes that are stable for quantification of gene expression across desired experimental conditions. Successful isolation of RNA with sufficient yield and quality is essential for downstream analyses involving nucleic acids. …”
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315716por Zhang, Zhe-Ao, Xin, Xin, Liu, Chao, Liu, Yan-hong, Duan, Hong-Xia, Qi, Ling-ling, Zhang, Ying-Ying, Zhao, He-ming, Chen, Li-Qing, Jin, Ming-Ji, Gao, Zhong-Gao, Huang, Wei“…Herein, we demonstrate the successful application of protein corona-mediated brain-targeted nanomicelles in the treatment of glioma, loading them with paclitaxel (PTX), and decorating them with amyloid β-protein (Aβ)-CN peptide (PTX/Aβ-CN-PMs). …”
Publicado 2021
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315717por Sintayehu, Kassech, Zeleke, Eden Dagnachew, Temesgen, Busha, Kifle, Meron, Assefa, Dawit Getachew, Zenebe, Kibebew, Kassahun, Ashenafi, Yimer, Ben Tegegn“…BACKGROUND: The health sectors success has been determined by consistent and reasonably priced health commodities supply. …”
Publicado 2022
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315718por McGraw, Constance, Mains, Charles W., Taylor, Jodie, D’Huyvetter, Cecile, Salottolo, Kristin, Bar-Or, David“…CONCLUSIONS: Our data suggest that most patients transferred from a remote facility had a splenic injury grade ≥ 3, with concomitant injuries but were hemodynamically stable and were successfully managed non-operatively. Stratifying by spleen grade may assist remote trauma centers with refining transfer criteria for solid organ injuries. …”
Publicado 2022
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315719por Ghazy, Ramy Mohamed, Ellakany, Walid Ismail, Badr, Mai M., Taktak, Nehad E. M., Elhadad, Heba, Abdo, Sarah M., Hagag, Ayat, Hussein, Abdel Rahman, Tahoun, Mohamed Mostafa“…Stool samples were collected from children aged 6–15 years on three successive days and examined using the Kato-Katz technique. …”
Publicado 2022
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315720por Saunders, Catherine H, Sierpe, Ailyn, Stevens, Gabrielle, Elwyn, Glyn, Cantrell, Matthew, Engel, Jaclyn, Gonzalez, Melissa, Hayward, Martha, Huebner, Joellen, Johnson, Lisa, Jimenez, Alejandro, Little, Nancy Ruth, McKenna, Corinne, Onteeru, Manu, Oo Khine, May, Pogue, Jacqueline, Salinas Vargas, José Luis, Schmidt, Peter, Thomeer, Rachael, Durand, Marie-Anne“…Through our trial, we will determine if this approach successfully improves vaccine confidence. If so, a similar social media resource could be used to develop curated social media interventions in other populations and with other public health goals.…”
Publicado 2022
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