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23861“…The Australian Government Department of Health (via the National Health and Medical Research Council) has commissioned a suite of independent evidence evaluations to inform the 2019-20 Review of the Australian Government Rebate on Private Health Insurance for Natural Therapies. …”
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23862por Leung, Shirley, Windbichler, Nikolai, Wenger, Edward A, Bever, Caitlin A, Selvaraj, Prashanth“…BACKGROUND: Gene drives are a genetic engineering method where a suite of genes is inherited at higher than Mendelian rates and has been proposed as a promising new vector control strategy to reinvigorate the fight against malaria in sub-Saharan Africa. …”
Publicado 2022
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23863por Næsborg-Nielsen, Christina, Wilkinson, Vicky, Mejia-Pacheco, Natalia, Carver, Scott“…We highlight the need for mange/scabies studies to more routinely compare immunological and clinical pathological changes against controls, and include collection of a more standardised suite of variables among studies. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12879-022-07635-5.…”
Publicado 2022
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23864por Soussain, Carole, Grommes, Christian, Issa, Samar, Ward, Renee, Peterson, Caryn, Cravets, Matt, Mathias, Anita, Sosa, Judith, Kirby, Brian, Ding, Zhaoqing, Yusuf, Isharat, Rose, Mark, Steinberg, Marcos, Tun, Han W“…GB5121 is a novel, orally available, covalent BTKi with superior specificity, CNS penetration, and CNS target occupancy in preclinical testing versus other BTKis including ibrutinib. GB5121 is well-suited for evaluation in CNS lymphoma. This is a phase 1b/2 open-label study of GB5121 in adults with R/R PCNSL, isolated SCNSL or PVRL and will be conducted in three parts: phase 1b dose-escalation, expansion, and phase 2. …”
Publicado 2022
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23865por Emons, Georg, Auslander, Noam, Jo, Peter, Kitz, Julia, Azizian, Azadeh, Hu, Yue, Hess, Clemens F., Roedel, Claus, Sax, Ulrich, Salinas, Gabriela, Stroebel, Philipp, Kramer, Frank, Beissbarth, Tim, Grade, Marian, Ghadimi, Michael, Ruppin, Eytan, Ried, Thomas, Gaedcke, Jochen“…Therefore, the classifier can identify patients suited for “watch and wait”.…”
Publicado 2022
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23866“…CONCLUSIONS: Interventions that focus on leisure-time physical activity appear to be best suited to improve depression, however, this needs to be confirmed in purposefully designed intervention studies. …”
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23867por Nguyen, Jack V. K., McKay, Adam, Ponsford, Jennie, Davies, Katie, Makdissi, Michael, Drummond, Sean P. A., Reyes, Jonathan, Willmott, Catherine“…Understanding the end-user perspective of the treatment will also enable modifications to the treatment protocol for future trials to best suit the needs of individuals with PPCSs after mTBI. …”
Publicado 2022
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23868por Saunders, W. B., Dejardin, L. M., Soltys-Niemann, E. V., Kaulfus, C. N., Eichelberger, B. M., Dobson, L. K., Weeks, B. R., Kerwin, S. C., Gregory, C. A.“…Conclusion: In a canine critical-sized defect model, the AS-ILN and described outcome measures allowed refinement and reduction consistent with the Principle of the 3R’s of ethical animal research. This model is well-suited for future canine translational bone tissue engineering studies.…”
Publicado 2022
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23869por Pazos-Castro, Diego, Margain, Clémence, Gonzalez-Klein, Zulema, Amores-Borge, Marina, Yuste-Calvo, Carmen, Garrido-Arandia, Maria, Zurita, Lucía, Esteban, Vanesa, Tome-Amat, Jaime, Diaz-Perales, Araceli, Ponz, Fernando“…VLPs derived from Turnip mosaic virus (TuMV) have proven to present a tridimensional structure suited to display molecules of interest on their surface, making them interesting tools to be studied in theragnostic strategies. …”
Publicado 2022
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23870por van der Pan, Kyra, de Bruin-Versteeg, Sandra, Damasceno, Daniela, Hernández-Delgado, Alejandro, van der Sluijs-Gelling, Alita J., van den Bossche, Wouter B. L., de Laat, Inge F., Díez, Paula, Naber, Brigitta A. E., Diks, Annieck M., Berkowska, Magdalena A., de Mooij, Bas, Groenland, Rick J., de Bie, Fenna J., Khatri, Indu, Kassem, Sara, de Jager, Anniek L., Louis, Alesha, Almeida, Julia, van Gaans-van den Brink, Jacqueline A. M., Barkoff, Alex-Mikael, He, Qiushui, Ferwerda, Gerben, Versteegen, Pauline, Berbers, Guy A. M., Orfao, Alberto, van Dongen, Jacques J. M., Teodosio, Cristina“…In summary, the two antibody combinations and FCM approach allow for rapid, standardized, automated and reproducible identification of 19 and 23 IMC populations in PB, suited for monitoring of innate immune responses in clinical and translational research settings.…”
Publicado 2022
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23871por Homaira, Nusrat, Dickins, Emma, Hodgson, Stephanie, Chan, Mei, Wales, Sandra, Gray, Melinda, Donnelly, Sarah, Burns, Christine, Owens, Louisa, Plaister, Michael, Flynn, Anthony, Andresen, Jennifer, Keane, Kimberley, Wheeler, Karen, Gould, Bronwyn, Shaw, Nadine, Jaffe, Adam, Breen, Christie, Altman, Lisa, Woolfenden, Susan“…Children aged 2–16 years who presented ≥4 times to the ED of the SCH,R in the preceding 12 months were enrolled in Phase I and those who had ≥4 ED presentations and ≥1 hospital admissions with asthma attack were enrolled in Phase II. Phase I included a suite of interventions delivered by CCs including encouraging parents/carers to schedule follow-up visits with GP post-discharge, ensuring parents/carers are provided with standard asthma resource pack, offering referrals to asthma education sessions, sending a letter to the child's GP advising of the child's recent hospital presentation and coordinating asthma education webinar for GPs. …”
Publicado 2022
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23872por Gilbertson, Marie L. J., Ketz, Alison C., Hunsaker, Matthew, Jarosinski, Dana, Ellarson, Wesley, Walsh, Daniel P., Storm, Daniel J., Turner, Wendy C.“…Across their wide range, WTD dispersal is believed to be driven by a suite of landscape and host behavioral factors, but these can vary by region, season, and sex. …”
Publicado 2022
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23873“…If tissue availability is limited, we recommend the snRNAseq procedure of fresh or frozen tissue samples as it is perfectly suited to obtain thorough insights into cellular diversity of complex tissue. …”
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23874“…MBC is the routine collection and use of client-reported progress measures to inform shared decision-making and collaborative treatment adjustments and is a relatively feasible and scalable clinical practice, particularly well-suited for under-resourced community mental health settings. …”
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23875por Sieland, Johanna, Niederer, Daniel, Engeroff, Tobias, Vogt, Lutz, Troidl, Christian, Schmitz-Rixen, Thomas, Banzer, Winfried, Troidl, Kerstin“…Steady state walking without the necessity to reach exhaustion seems to be better suited as stimulus. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00421-022-05091-2.…”
Publicado 2022
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23876por Austin, Andrea M., Ramkumar, Niveditta, Gladders, Barbara, Barnes, Jonathan A., Eid, Mark A., Moore, Kayla O., Feinberg, Mark W., Creager, Mark A., Bonaca, Marc, Goodney, Philip P.“…Random forests are incredibly high performing models with difficult interpretation most ideally suited for times when accurate prediction is most desirable and can be used in tandem with more common approaches to provide a more thorough analysis of observational data. …”
Publicado 2022
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23877por Butowicz, Courtney M., Hendershot, Brad D., Watson, Nora L., Brooks, Daniel I., Goss, Donald L., Whitehurst, Robert A., Harvey, Alisha D., Helton, Matthew S., Kardouni, Joseph R., Garber, Matthew B., Mauntel, Timothy C.“…The objective of the “Pre-neuromusculoskeletal injury Risk factor Evaluation and Post-neuromusculoskeletal injury Assessment for Return-to-duty/activity Enhancement (PREPARE)” study is to develop a comprehensive suite of clinical assessments to identify the patient-specific factors contributing to MSKI risks and undesired post-MSKI outcomes. …”
Publicado 2022
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23878“…OBJECTIVE: This study aims to evaluate how the WiserAD approach to antidepressant deprescribing works, whom it is for, and the underlying circumstances by (1) examining the experiences and perceptions of WiserAD among antidepressant users, (2) identifying the underlying mechanisms of the WiserAD approach to antidepressant deprescribing, and (3) describing in what contexts and to what extent the underlying mechanisms of WiserAD are suited for antidepressant users. METHODS: A mixed methods case study with realist evaluation will be conducted among participants in the WiserAD randomized controlled trial for antidepressant deprescribing. …”
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23879por Shapaval, V., Deniset-Besseau, A., Dubava, D., Dzurendova, S., Heitmann Solheim, J., Kohler, A.“…RESULTS: Both transmission- and reflectance-based spectroscopy techniques are shown to be well suited for studying bulk fungal biomass. Exploring single cells with infrared microspectroscopy reveals differences in chemical profiles and, consequently, lipogenesis process, for different cell forms. …”
Publicado 2023
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23880por Nguyen, Quang Huy, Ming, Damien K., Luu, An Phuoc, Chanh, Ho Quang, Tam, Dong Thi Hoai, Truong, Nguyen Thanh, Huy, Vo Xuan, Hernandez, Bernard, Van Nuil, Jennifer Ilo, Paton, Chris, Georgiou, Pantelis, Nguyen, Nguyet Minh, Holmes, Alison, Tho, Phan Vinh, Yacoub, Sophie“…Understanding the decision-making process in greater detail also allows for development and implementation of CDSS which are suited to the local context. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12911-023-02116-4.…”
Publicado 2023
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