“…High index of clinical suspicion and prompt diagnosis are the most important factors of patient management, especially in cases of life threatening neonatal infections. …”
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“…The case highlights the importance of a high index of suspicion, careful clinical evaluation in patients with iron toxicity, and the need for individualized treatment decisions based on the patient's clinical presentation and laboratory values.…”
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“…Despite the low incidence of varicella pneumonia among patients with primary varicella infection, the index of suspicion for varicella pneumonia among patients with primary varicella infection should be high in the setting of increased oxygen requirements due to the mortality and symptomatic benefits of early treatment.…”
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“…Diagnosis of PRES following rituximab treatment requires a high index of suspicion correlated with clinical and radiological features in individuals at risk. …”
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“…Due to the high initial suspicion for gout, early spinal decompression surgery was performed, and the patient was started on medical therapy. …”
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“…A patient’s medical history can often raise clinical suspicion of phytobezoars. However, a careful etiological investigation is imperative in all cases of mechanical ileus in advanced ages; early detection and dissolution of phytobezoars, when applicable, can reduce the need for surgical interventions.…”
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“…Serial measurement of head circumference is essential to prompt diagnostic suspicion in the case of paediatric meningitis.…”
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“…Although rare and only found in 1% of the cases, aNET found in family history should raise the suspicion of neuroendocrine tumors in other family members.…”
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“…This report emphasizes that a high index of suspicion is needed to diagnose a rare condition with such variable manifestations as Behcet's disease and that early detection and immunosuppression therapy can confer improved prognosis.…”
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“…The patient was suffering from worsening tinnitus along with hearing impairment. High clinical suspicion of jugular paraganglioma prevented us from taking a biopsy. …”
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“…Spot urine testing for PBG and urine porphyrins should be initiated early in patients with clinical suspicion of AHP.…”
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“…Identifying these rare disease processes requires a high index of suspicion and a work-up strategy that includes consideration of medical history in combination with lab and imaging findings to determine appropriate interventions.…”
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“…These clinical and laboratory findings raised suspicion of HLH secondary to typhoid fever. Further investigations were suggestive of hyperferritinemia and hypofibrinogenemia, and bone marrow aspirates showed hemophagocytes. …”
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“…Patients with leukocytosis and thrombocytosis should raise clinical suspicion that hyperkalemic laboratory results in the absence of other traditional signs of hyperkalemia may be indicative of pseudohyperkalemia. …”
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“…Abnormal enhancement should raise the suspicion of malignancy of a lingual foregut duplication cyst. …”
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“…The lack of diagnosis was due, in part, to her atypical symptoms and laboratory findings that required a high level of clinical suspicion to diagnose. Extensive autoimmune workup was largely unrevealing with the exception of a cold agglutinin titer of 1:250 and a positive anticomplement C3b direct antiglobulin test. …”
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“…Due to the rarity of such cases and reports limitations in the literature, the diagnosis of neurofibroma of the external genitalia requires a high index of suspicion by health-care providers. Surgical excision and postoperative follow-up for possible recurrence remain the gold standard of management.…”
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“…A newfound hypoalbuminemia raised the suspicion of a protein-losing condition, with an upper endoscopy revealing lesions at the D2 level compatible with coeliac sprue and HLA typing positive for both DQ-2 and DQ-8. …”
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“…Due to the absence of apparent immunosuppressive conditions or identifiable risk factors during evaluation, our suspicion for fungal meningitis was low. However, the diagnosis was confirmed through CSF fluid analysis, leading to the immediate initiation of guideline-directed treatment with amphotericin and fluconazole. …”
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“…KEY CLINICAL MESSAGE: Infective endocarditis should be considered in any febrile individual with acute onset neurological symptoms. If suspicion is high, a negative brain computed tomography does not virtually exclude embolism, and magnetic resonance imaging is warranted. …”
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