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221por Liljavirta, Jenni, Niku, Mikael, Pessa-Morikawa, Tiina, Ekman, Anna, Iivanainen, Antti“…We have investigated the importance of terminal deoxynucleotidyl transferase (TdT) -mediated junctional diversity to the bovine immunoglobulin repertoire. …”
Publicado 2014
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222por Wang, Jing-Han, Guo, Qi, Ma, Zhi-Xin, Ma, Qiu-Ling, Yu, Meng-Xia, Yin, Xiu-Feng, Lu, Sha-Sha, Xie, Hong-Qiong, Jiang, Yue-Hong, Shen, Dan, Ma, Li-Ya, Shi, Hui, Yu, Wen-Juan, Lou, Ye-Jiang, Li, Ying, Yang, Min, Xu, Gai-Xiang, Mao, Li-Ping, Li, Jian-Hu, Wang, Huan-Ping, Wang, Dong-Mei, Wei, Ju-Ying, Tong, Hong-Yan, Huang, Jian, Jin, Jie“…The effect of time from diagnosis to treatment (TDT) on overall survival of patients with acute myeloid leukemia (AML) remains obscure. …”
Publicado 2015
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223“…Three major analytical methods were used: transmission disequilibrium test (TDT), TDT allowing for errors (TDTae), and linkage analysis under dominant and recessive inheritance. …”
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224por Aydinok, Yesim, Piga, Antonio, Origa, Raffaella, Mufti, Nina, Erickson, Anna, North, Anne, Waldhaus, Katie, Ernst, Christine, Lin, Jin‐Sying, Huang, Norman, Benjamin, Richard J., Corash, Laurence“…Transfusion‐dependent thalassaemia (TDT) requires red blood cell concentrates (RBCC) to prevent complications of anaemia, but carries risk of infection. …”
Publicado 2019
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225por Zhang, Kun, Cheng, Xiaoting, Zhao, Liping, Huang, Mingqian, Tao, Yong, Zhang, Hongbo, Rosenholm, Jessica M., Zhuang, Min, Chen, Zheng-Yi, Chen, Bing, Shu, Yilai“…The optimal concentration was 22.5 μM with the highest transfection efficiency and the lowest cytotoxicity. Wide-spread tdT signals were detected in the cochlear-supporting cells, utricular-supporting cells, auditory nerve, and spiral ligament in neonatal and adult mice. …”
Publicado 2020
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226por Shalash, Ali S., Hamid, Eman, Elrassas, Hanan, Bahbah, Eshak I., Mansour, Alia H., Mohamed, Hadeer, Elbalkimy, Mahmoud“…OBJECTIVES: To compare non-motor symptoms (NMSs) among patients with essential tremor (ET), Parkinson’s disease (PD) subtypes (akinetic-rigid type (ART) and tremor-dominant type (TDT)), and healthy controls. PATIENTS AND METHODS: This retrospective study included 129 participants, 72 PD (33 PD-ART, 33 PD-TDT, and 6 Mixed), 29 ET patients, and 28 controls. …”
Publicado 2021
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227por Sidhu, Sukhmani, Kakkar, Shruti, Dewan, Priyanka, Bansal, Namita, Sobti, Praveen C.“…Materials and Methods: Patients with TDT on ICT for > 6 months were enrolled in the study. …”
Publicado 2021
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228“…Therefore, a nonsystematic review was conducted on above three studies to ascertain the enhanced effectiveness and tolerability of twice per day regimen of deferasirox with the same total dose as that of once daily regimen of deferasirox in unresponsive or intolerant transfusion-dependent beta-thalassemia (TDT) patients. All the above studies concluded that the twice per day regimen of deferasirox was more efficacious and tolerable among TDT patients when compared to the once-a-day regimen with the same total daily dose. …”
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229por Chan, Moon Fai, Alsaidi, Yaqoub, Al-Sumri, Sana, Al-Maskari, Buthaina, Al-Hamrashdi, Hajer“…CONCLUSION: findings might help primary health care authorities to address this preventable issue and plan interventions to establish well-structured TDT clinics in the future.…”
Publicado 2021
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230por Li, Xinyu, Hu, Shuting, Liu, Yong, Huang, Junjiu, Hong, Weicong, Xu, Luhong, Xu, Honggui, Fang, Jianpei“…However, the evidence about the safety and efficacy of thalidomide on children with transfusion dependent β-thalassemia (TDT) is scarce. Methods: Seventy-seven children with TDT treated with thalidomide at least for 6 months were included and retrospectively analyzed. …”
Publicado 2021
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231por Photia, Apichat, Traivaree, Chanchai, Monsereenusorn, Chalinee, Simthamnimit, Piyarat, Rujkijyanont, Piya“…This study aimed to evaluate the efficacy of furosemide to prevent volume overload among children and young adults diagnosed with TDT. METHODS: Patients diagnosed with TDT were enrolled and randomized to receive either furosemide pretransfusion or no furosemide pretransfusion. …”
Publicado 2020
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232por Chan, Kate C., Au, Chun T., Leung, Alex W. K., Li, Albert M., Li, Chi-kong, Wong, Matthew M. T., Li, Carol S. T., Cheung, Hang L., Fan, Philip, Ling, Siu C., Li, Rever C. H., Ha, S. Y.“…In patients with transfusion-dependent thalassemia (TDT), pulmonary function impairment has been reported but data are conflicting. …”
Publicado 2023
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233por Zucano, Stefania, Tarantini, Francesco, Vitucci, Angelantonio, Palma, Antonio, Campanale, Daniela, Vimercati, Luigi, Larocca, Angela Maria Vittoria, Visceglie, Domenico, Acquafredda, Amalia, Tafuri, Silvio, Musto, Pellegrino“…Nevertheless, antibody titers in TDT patients were significantly lower than in HC. …”
Publicado 2021
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234por McGlinchey, Paul G., Spence, Mark S., Patterson, Chris C., Allen, Adrian R., Murphy, Gillian, Fogarty, Damian, Evans, Alun, McKeown, Pascal P.“…Using the combined transmission disequilibrium test (TDT)/sib-TDT and the pedigree disequilibrium test (PDT), no association between the MMP-3 -1612 5A/6A polymorphism and IHD was found. …”
Publicado 2004
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235“…SUMMARY: Tardive dystonia (TDt), a cluster of extrapyramidal symptoms that are caused by long-term use of antipsychotic medication, is characterized by difficulty in autonomic movements of skeletal (voluntary) muscles and consequent deformations of the body. …”
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236“…CASE REPORT: We report a case of 14-year-old male with transfusion-dependent thalassemia (TDT) and hepatitis C, who developed bilateral atraumatic AVNF requiring surgical correction. …”
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237por Haghpanah, Sezaneh, Zekavat, Omid Reza, Bordbar, Mohammadreza, Karimi, Mehran, Zareifar, Soheila, Safaei, Sanaz, Ramzi, Mani, Ashraf, Hossein“…BACKGROUND: Ocular involvement may occur via several mechanisms in patients with transfusion-dependent β-thalassemia (TDT) mainly chronic anemia, iron overload and iron chelator toxicity. …”
Publicado 2020
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238por Dissanayake, Ruwangi, Samarasinghe, Nayana, Waidyanatha, Samantha, Pathirana, Sajeewani, Neththikumara, Nilaksha, Dissanayake, Vajira H. W., Wetthasinghe, Kalum, Gooneratne, Lallindra, Wickramasinghe, Pujitha“…BACKGROUND: Iron overload (IO) is a complication in transfusion dependent beta thalassaemia (TDT). Pathogenic variants in genes involving iron metabolism may confer increased risk of IO. …”
Publicado 2022
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239por Huang, Mengqi, Sun, Zeliang, Yan, Gerald, Xie, Hongchao, Agarwal, Nishkarsh, Ye, Gaihua, Sung, Suk Hyun, Lu, Hanyi, Zhou, Jingcheng, Yan, Shaohua, Tian, Shangjie, Lei, Hechang, Hovden, Robert, He, Rui, Wang, Hailong, Zhao, Liuyan, Du, Chunhui Rita“…Here we report spin defect-based wide-field imaging of magnetic domains and spin fluctuations in twisted double trilayer (tDT) chromium triiodide CrI(3). We explicitly show that intrinsic moiré domains of opposite magnetizations appear over arrays of moiré supercells in low-twist-angle tDT CrI(3). …”
Publicado 2023
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240por Khan, H., Panjwani, V., Al Rahbi, S., Eltigani, A, Qureshi, R.N., Unissa, K., Sehar, N., Mittal, A., Pathare, A.V.“…AIMS: In a longitudinal study, we aimed to assess the correlation between ultrasound transient elastography (TE), serum ferritin (SF), liver iron content (LIC) by magnetic resonance imaging (MRI) T2* along with the fibrosis-4 (FIB-4) score as a screening tool to detect significant liver fibrosis among chronically transfusion-dependent beta-thalassemia (TDT) patients. METHODS: The study was conducted at a tertiary health center treating TDT patients. …”
Publicado 2023
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