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21por Londono, Douglas, Buyske, Steven, Finch, Stephen J, Sharma, Swarkar, Wise, Carol A, Gordon, Derek“…CONCLUSIONS: We have developed an extension of the TDT statistic (TDT-HET) that allows for locus heterogeneity among coded trios. …”
Publicado 2012
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22“…Data from case-control and TDT studies were integrated in an allelic model using the Catmap and Metafor software. …”
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24por Pozner, Amir, Xu, Ben, Palumbos, Sierra, Gee, J. Michael, Tvrdik, Petr, Capecchi, Mario R.Enlace del recurso
Publicado 2015
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25por Shi, Tianhui, Wang, Menglin, Li, Hao, Wang, Miao, Luo, Xingyu, Huang, Yan, Wang, Hong-Hui, Nie, Zhou, Yao, ShouzhuoEnlace del recurso
Publicado 2018
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26“…Cultured HL‐60, HeLa S3 and WiDr cells grown in male BALB/c nu/nu mice were studied by conventional and field‐inversion DNA gel electrophoresis (FIGE), as well as by means of cytomorphological approaches, including TdT‐mediated dUTP nick end labeling (TUNEL) assay. …”
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27por Zhang, Bo, Li, Shuangming, Wang, Huamiao, Tang, Weiqin, Jiang, Yaodong, Wu, Peidong“…As a consequence, the conjunction of viscoplastic self-consistent model and twinning and detwinning scheme (VPSC–TDT) is employed to investigate the in-plane anisotropy of magnesium alloy AZ31B-O sheet. …”
Publicado 2019
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28por Lang, Mingjian, Luo, Dan, Yang, Guangyi, Mei, Quanxi, Feng, Guangjun, Yang, Yang, Liu, Zhaohui, Chen, Qinhua, Wu, Lun“…In the presence of terminal deoxynucleotidyl transferase (TdT) and dTTP, TdT mediated P1 to extend and formed the structure of poly T. …”
Publicado 2020
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29por Angirekula, Mounika, Chang, Sindy Y, Jenkins, Sarah M., Greipp, Patricia T., Sukov, William R., Marks, Randolph S., Olivier, Kenneth R., Cassivi, Stephen D., Roden, Anja C“…IHC was performed using antibodies against TdT, Glut-1, CD5, CD117, BAP1, and mTAP. Percent tumor cell staining was recorded (Glut-1, CD5, CD117); loss of expression (BAP1, mTAP) was considered if essentially all tumor cells were negative; TdT was recorded as thymocytes present or absent (including rare thymocytes). …”
Publicado 2022
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31por Di Maio, Salvatore, Marzuillo, Pierluigi, Mariannis, Demetris, Christou, Soteroula, Ellinides, Andreas, Christodoulides, Costantinos, de Sanctis, Vincenzo“…Serum ferritin levels (SF) were significantly correlated with the age at starting chelation therapy (n = 79; r = 0,34; p = 0,022). In 56 TDT adolescents who developed secondary amenorrhea (SA), the SF levels were significantly higher (4,098 ± 1,907 ng/mL) compared to 23 TDT adolescents with regular menstrual cycles (2,913±782 ng/mL; p = 0,005). …”
Publicado 2021
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32por Luo, Sai, Jing, Changbin, Ye, Adam Yongxin, Kratochvil, Sven, Cottrell, Christopher A., Koo, Ja-Hyun, Chapdelaine Williams, Aimee, Francisco, Lucas Vieira, Batra, Himanshu, Lamperti, Edward, Kalyuzhniy, Oleksandr, Zhang, Yuxiang, Barbieri, Alessandro, Manis, John P., Haynes, Barton F., Schief, William R., Batista, Facundo D., Tian, Ming, Alt, Frederick W.“…V(D)J junctional regions encode complementarity-determining-region 3 (CDR3), an antigen-contact region immensely diversified through nontemplated nucleotide additions (“N-regions”) by terminal deoxynucleotidyl transferase (TdT). HIV-1 vaccine strategies seek to elicit human HIV-1 broadly neutralizing antibodies (bnAbs), such as the potent CD4-binding site VRC01-class bnAbs. …”
Publicado 2022
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33Publicado 1984“…The cultured TdT+ cells are antigenically "null" cells that further resemble their normal counterparts in bone marrow with respect to morphology, size, cortisone sensitivity, and pattern of TdT fluorescence. …”
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34“…Two murine isoforms of TdT, with a length difference of twenty residues and having different biochemical properties, have been studied. …”
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35por Rother, Magdalena B., Jensen, Kristin, van der Burg, Mirjam, van de Bovenkamp, Fleur S., Kroek, Roel, van IJcken, Wilfred F. J., van der Velden, Vincent H. J., Cupedo, Tom, Olstad, Ole K., van Dongen, Jacques J. M., van Zelm, Menno C.“…Analysis of progenitor-B cells from IL7Rα-deficient patients revealed that TdT expression and N-nucleotides additions in Dh-Jh junctions were dependent on functional IL7Rα. …”
Publicado 2016
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36por De Sanctis, Vincenzo, Soliman, Ashraf T., El-Hakim, Ihab, Christou, Soteroula, Mariannis, Demetris, Karimi, Mehran, Ladis, Vassilis, Kattamis, Antonis, Daar, Shahina, Yassin, Mohamed, Canatan, Duran, Galati, Maria Concetta, Raiola, Giuseppe, Campisi, Saveria, Kakkar, Shruti, Kaleva, Valeria, Saki, Forough, Ellinides, Andreas, Pikis, Giorgos, Christodoulides, Constantinos, Abdulla, Mohamed, Di Maio, Salvatore, Theodoridis, Charalambos, Elsedfy, Heba, Kattamis, Christos“…Of 184 patients, 150 (81.5%) had natural conception, 23 (12.5%) required induction of spermatogenesis with gonadotropins (hCG and hMG), 8 (4.3%) needed intracytoplasmic sperm injection (ICSI) and 3 adopted a child. 39 patients with TDT and NTDT asked for medical help as they were unable to father naturally: 7 TDT patients (17.9%) were azoospermic, 17 (37.7%) [13 with TDT and 4 with NTDT] had dysspermia and 15 (33.3%) [13 with TDT and 2 with NTDT] had other “general medical and non-medical conditions”. …”
Publicado 2019
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37por Yuenyongviwat, Varah, Iamthanaporn, Khanin, Tuntarattanapong, Pakjai, Hongnaparak, Theerawit, Tangtrakulwanich, Boonsin“…However, the evidence of TDT 064 in treatment of knee osteoarthritis is limited. …”
Publicado 2021
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38por Tzoulis, Ploutarchos, Yavropoulou, Maria P., Banchev, Atanas, Modeva, Iskra, Daar, Shahina, De Sanctis, Vincenzo“…PURPOSE OF REVIEW: The aim of this short review is to provide an update on glucose homeostasis, insulin secretion and pharmacological management of osteoporosis in transfusion-dependent thalassemia (TDT). RECENT FINDINGS: A retrospective study, documenting the changes in glucose-insulin homeostasis from early childhood to young adulthood, has advanced our understanding of the evolution of glucose regulation in patients with TDT. …”
Publicado 2023
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39“…BACKGROUND: Two factors impacting robustness of the original transmission disequilibrium test (TDT) are: i) missing parental genotypes and ii) undetected genotype errors. …”
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40por De Sanctis, Vincenzo, Soliman, Ashraf T, Tzoulis, Ploutarchos, Daar, Shahina, Di Maio, Salvatore, Fiscina, Bernadette, Kattamis, Christos“…Therefore, an early diagnosis requires an annual oral glucose tolerance test (OGTT) in all TDT patients aged ten years or older. PURPOSE: This retrospective study aims to evaluate the prevalence of GD in a homogenous population of prepubertal TDT patients and to enhance understanding of the pathogenesis and progression of glucose homeostasis in this group of patients. …”
Publicado 2021
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