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Mostrando 81 - 100 Resultados de 1,074 Para Buscar '"TDT"', tiempo de consulta: 0.17s Limitar resultados
  1. 81
    “…In Tdt°/° animals, TCRBV chain diversity is reduced 10-fold compared with wild-type mice. …”
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    Most α/β T Cell Receptor Diversity Is Due to Terminal Deoxynucleotidyl Transferase
  2. 82
    “…We aimed to assess TdT staining in skin biopsies with similar-appearing lymphocytic infiltrates. …”
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    Cutaneous T-Cell Acute Lymphoblastic Leukemia and the Expression Pattern of Terminal Deoxynucleotidyl Transferase Immunostaining in Mycosis Fungoides and Spongiotic Dermatitis
  3. 83
    “…METHODS: Parents of children with TDT and adults with TDT were who provided informed consent underwent semi-structured interviews to understand patient/family knowledge and decision-making regarding GT in TDT. …”
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    Decision-making about gene therapy in transfusion dependent thalassemia
  4. 84
    “…TDT techniques, on the other hand, are mostly performed with specialized bulky laboratory equipment, such as a Vector Network Analyzer (VNA) which makes TDT measurements prohibitively costly and unpractical. …”
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    Time-domain transmission sensor system for on-site dielectric permittivity measurements in soil: A compact, low-cost and stand-alone solution
  5. 85
    “…CONCLUSIONS: Levels of Tregs and MDSCs increased in TDT and may probably have a role in suppressing the active immune systems of TDT patients.…”
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    Could the Crosstalk Between Myeloid-Derived-Suppressor Cells and Regulatory T Cells Have a Role in Beta-Thalassemia?
  6. 86
    “…Terminal deoxynucleotidyl transferase (TdT) was estimated in the tissues of 42 patients with lymphoma, whose cells were also typed by the use of surface markers. …”
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    Terminal deoxynucleotidyl transferase activity in lymphoma.
  7. 87
    “…This cross-sectional analytical study was performed on 389 TDT patients who were under treatment in four thalassemia centers in Tehran, Iran. …”
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    Predictors of Quality of Life in Transfusion-dependent Thalassemia Patients Based on the PRECEDE Model: A Structural Equation Modeling Approach
  8. 88
    “…The extent of thermal damage was determined using thermal damage threshold (TDT) lines: yellow TDT line (43°C for 2 min) and blue TDT line (43°C for 10 min). …”
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    The role of laser interstitial thermal therapy in enhancing progression-free survival of difficult-to-access high-grade gliomas: a multicenter study
  9. 89
    Publicado 1975
    “…Other tissues, such as spleen, liver, heart, and brain lack detectable amounts of TdT activity.…”
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    Murine terminal deoxynucleotidyl transferase: cellular distribution and response to cortisone
  10. 90
    “…Using two newly generated transgenic mice that report and trace the expression of terminal deoxynucleotidyl transferase (TdT), transient induction of TdT was detected on a newly identified multipotent progenitor (MPP) subset that lacked self-renewal capacity but maintained multilineage differentiation potential. …”
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    Dntt expression reveals developmental hierarchy and lineage specification of hematopoietic progenitors
  11. 91
    “…METHODS: We conducted a prospective, observational, real-world study of adults with TDT and caregivers of adolescents with TDT, in Italy, the UK, and the USA. …”
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    Patient- and Caregiver-Reported Burden of Transfusion-Dependent β-Thalassemia Measured Using a Digital Application
  12. 92
    “…This study aimed to determine the effect of zinc deficiency and iron overload on the endocrine and exocrine pancreas in TDT children. METHODS: Eighty children, already diagnosed with TDT, were included in this study. …”
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    The effect of zinc deficiency and iron overload on endocrine and exocrine pancreatic function in children with transfusion-dependent thalassemia: a cross-sectional study
  13. 93
    “…However, changing the orientation of the background lines midway through TDT training interferes with overnight improvements in overall performance on TDT. …”
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    Frequent Video Game Players Resist Perceptual Interference
  14. 94
    “…Here, we described two parallel efforts to improve the activity of TdT on hairpins: (1) optimization of the concentrations of the divalent cation cofactors and (2) engineering TdT for enhanced thermostability, enabling reactions at elevated temperatures. …”
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    Enhancing Terminal Deoxynucleotidyl Transferase Activity on Substrates with 3′ Terminal Structures for Enzymatic De Novo DNA Synthesis
  15. 95
    “…Their production is regulated by variations in thymic output and terminal deoxynucleotidyl transferase (TDT) activity. Neonatal TCRs derived from TDT-negative progenitors persist throughout life, are highly shared among subjects, and are reported as disease-associated. …”
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    Two types of human TCR differentially regulate reactivity to self and non-self antigens
  16. 96
    “…AIM: To reveal the effect of TDT in patients with symptomatic AL after rectal cancer surgery. …”
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    Efficacy of transanal drainage tube in preventing anastomotic leakage after surgery for rectal cancer: A meta-analysis
  17. 97
    Publicado 1987
    “…Three discrete cell populations were thus defined, differing in mean cell diameter TdT+ 14.8- mu-, 9.5 micron; TdT+ 14.8+ mu-, 10 microns; and TdT- 14.8+ mu-, 11.5 micron, presumptively representing a sequence of cell stages preceding the expression of mu chains in large pre-B cells (TdT- 14.8+ c mu+ s mu-, 11.5 microns). …”
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    Phenotype and proliferation of early B lymphocyte precursor cells in mouse bone marrow
  18. 98
    “…Regular blood transfusions in transfusion-dependent thalassemia (TDT) patients can lead to iron overload, causing oxidative stress and sympathovagal imbalance, resulting in increased cardiac complications. …”
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    N-acetylcysteine Restored Heart Rate Variability and Prevented Serious Adverse Events in Transfusion-dependent Thalassemia Patients: a Double-blind Single Center Randomized Controlled Trial
  19. 99
    “…Herein, we propose a simple but highly sensitive flow cytometric immunoassay (FCI) by employing on-bead terminal deoxynucleotidyl transferase (TdT)-initiated template-free DNA extension as an effective signal amplification pathway (TdT-FCI), and gold nanoparticles (AuNPs) co-functionalized with both the detection antibody and a 3′-OH oligonucleotide (ODN) as the transducer to bridge the immunoassay and subsequent TdT-mediated DNA amplification. …”
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    An ultrasensitive flow cytometric immunoassay based on bead surface-initiated template-free DNA extension
  20. 100
    Publicado 1980
    “…A method is described by which highly enriched populations of viable terminal deoxynucleotidyl transferase-positive (TdT+) cells can be isolated from rat bone marrow by use of the fluorescence-activated cell sorter. …”
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    Analysis of rat hemopoietic cells on the fluorescence-activated cell sorter. II. Isolation of terminal deoxynucleotidyl transferase-positive cells
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