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2641por Burch, Henry B., Perros, Petros, Bednarczuk, Tomasz, Cooper, David S., Dolman, Peter J., Leung, Angela M., Mombaerts, Ilse, Salvi, Mario, Stan, Marius N.“…Thyroid eye disease (TED) remains challenging for clinicians to evaluate and manage. …”
Publicado 2022
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2642por Douglas, Raymond S, Couch, Steven, Wester, Sara T, Fowler, Brian, Liu, Catherine, Subramanian, Prem, Tang, Rosa, Nguyen, Quang T, Hsu, Kate, Karon, Michael, Stan, Marius N“…In a published study of 31 patients with CAS≤3 and TED duration >2 years, teprotumumab reduced proptosis, diplopia and inflammation.(1) We have undertaken the first randomized, placebo (PBO)-controlled trial to evaluate teprotumumab in patients with chronic/inactive/low CAS TED. …”
Publicado 2023
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2643por Gulbins, Anne, Horstmann, Mareike, Keitsch, Simone, Soddemann, Matthias, Wilker, Barbara, Wilson, Gregory C., Zeidan, Ryan, Hammer, Gary D., Daser, Anke, Bechrakis, Nikolaos E., Görtz, Gina-Eva, Eckstein, Anja“…Overstimulation of the TSHR induces hyperthyroidism and thyroid eye disease (TED) as the most common extra thyroidal manifestation of Graves’ disease. …”
Publicado 2023
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2644por Luzon, Javier A., Stimec, Bojan V., Bakka, Arne O., Edwin, Bjørn, Ignjatovic, Dejan“…Target error distance (TED) was obtained in three different working axes-(XYZ). …”
Publicado 2020
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2645“…METHODS: A retrospective cohort study of TED patients with active moderate/severe to sight-threatening TED seen over a 4-year period. …”
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2646por Lee, Bradford W., Kumar, Virender B., Biswas, Pooja, Ko, Audrey C., Alameddine, Ramzi M., Granet, David B., Ayyagari, Radha, Kikkawa, Don O., Korn, Bobby S.“…The IL-5 and chemokine signaling pathways were highly enriched, and very-low-density-lipoprotein receptor activity and statin medications were implicated as having a potential role in TED. CONCLUSION: This study is the first to use RNA-Seq technology to elucidate differential gene expression associated with active, severe TED. …”
Publicado 2018
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2647“…TED signs appeared within 6 months prior to treatment. …”
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2648por Meier, Tabea, Boyd, Ryan L., Mehl, Matthias R., Milek, Anne, Pennebaker, James W., Martin, Mike, Wolf, Markus, Horn, Andrea B.“…In a pre-registered study, we collected transcripts of TED Talks along with their impact measures, i.e., views and ratios of positive and negative talk ratings, from the TED website. …”
Publicado 2020
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2649por Sharma, Madhvi, Patgiri, Biswajyoti, Nariya, Mukesh B., Jamadagni, Shrirang, Bedarkar, Prashant“…The test drug was administered orally once a day for 90 consecutive days in the dose of 11.25 (therapeutic dose [TED]), 56.25 (5 times TED) and 112.25 mg/kg (10 times TED). …”
Publicado 2020
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2650“…Thyroid eye disease (TED) causes orbital soft-tissue expansion. Recent studies have suggested that brow and temple changes may also occur. …”
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2651“…PURPOSE: Teprotumumab, a specific blocking antibody to the insulin like growth factor 1 receptor, significantly reduced proptosis in patients with thyroid eye disease (TED) in recent clinical trials. Given its specificity, we expect it to demonstrate greater efficacy on the worse affected orbit, in patients with asymmetric TED. …”
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2652por Knecht, M, Bay, A, Blanc, F, Bettler, M-O, Conti, G, Fave, V, Frei, R, Gauvin, N, Haefeli, G, Keune, A, Luisier, J, Muresan, R, Nakada, T, Needham, M, Nicolas, L, Perrin, A, Potterat, C, Schneider, O, Tran, M, Bauer, C, Britsch, M, Hofmann, W, Maciuc, F, Schmelling, M, Voss, H, Anderson, J, Buechler, A, Chiapolini, N, Hangartner, V, Salzmann, C, Steiner, S, Steinkamp, O, Van Tilburg, J, Tobin, M, Vollhardt, A, Adeva, B, Fungueiri no Pazos, J, Gallas, A, Pazos-Alvarez, A, Pérez-Trigo, E, Pló-Casasus, M, Rodriguez Perez, P, Saborido, J, Vázquez, P, Iakovenko, V, Okhrimenko, O, Pugatch, V“…Results of these studies together and the overall detector performance obtained in the TED running will be discussed.…”
Publicado 2011
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2653por Kamalov, Armais, Kapranov, Sergei, Neymark, Alexander, Kurbatov, Dmitry, Neymark, Boris, Karpov, Valery, Shaparov, Boris“…Both Quality of Life score and International Prostate Symptom Score were around three times better in the PErFecTED group and remained stable during the entire observation period. …”
Publicado 2020
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2654por Douglas, Raymond S, Couch, Steven, Wester, Sara T, Fowler, Brian T, Liu, Catherine, Subramanian, Prem, Tang, Rosa, Nguyen, Quang T, Maamari, Robi N, Hsu, Kate, Karon, Michael, Stan, Marius“…Conclusions: For the first time in pts with longstanding TED and low CAS/inflammation, a medical therapy, teprotumumab, produced significant improvement in proptosis as compared with PBO supporting its use regardless of TED duration or activity. …”
Publicado 2023
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2655por Lerendegui-Marco, Jorge, Balibrea-Correa, Javier, Babiano-Suárez, Víctor, Ladarescu, Ion, Domingo-Pardo, César“…In this work, we report on the advantageous aspects of the i-TED detector for proton-range monitoring, based on the results of the first Monte Carlo study of its applicability to this field. i-TED is an array of Compton cameras, that have been specifically designed for neutron-capture nuclear physics experiments, which are characterized by [Formula: see text] -ray energies spanning up to 5–6 MeV, rather low [Formula: see text] -ray emission yields and very intense neutron induced [Formula: see text] -ray backgrounds. …”
Publicado 2022
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2656“…TED was designed to detect the different types of anomalies commonly present in OCT images for diagnostic purposes and thus aid clinical interpretation. …”
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2657“…OBJECTIVES: We aimed to evaluate the effect of tracheoesophageal diversion and laryngotracheal separation (TED-LTS) procedures for these patients. Material and Methods. …”
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2658por Ueland, Hans Olav, Ulvik, Arve, Løvås, Kristian, Wolff, Anette S B, Breivik, Lars Ertesvåg, Stokland, Ann-Elin Meling, Rødahl, Eyvind, Nilsen, Roy Miodini, Husebye, Eystein, Ueland, Grethe Åstrøm“…OBJECTIVE: This work aimed to characterize the kynurenine pathway, activated during interferon-γ (IFN-γ)–mediated inflammation and cellular (T-helper type 1 [Th1] type) immunity, in GD patients with and without thyroid eye disease (TED). METHODS: We analyzed 34 biomarkers by mass spectrometry in serum samples from 100 patients with GD (36 with TED) and 100 matched healthy controls. …”
Publicado 2023
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2659“…The high conformational variability of TED in C3b in physiological buffer showed that C3b is more reactive than previously thought. …”
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2660“…BACKGROUND: This study aimed to evaluate the efficacy of transforaminal endoscopic discectomy (TED) in the treatment of obese patients with lumbar disc herniation (LDH). …”
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