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2121por Högberg, Camilla, Billstedt, Eva, Björck, Caroline, Björck, Per-Olof, Ehlers, Stephan, Gustle, Lars-Henry, Hellner, Clara, Höök, Henrik, Serlachius, Eva, Svensson, Mats A., Larsson, Jan-Olov“…OPA was highest for Obsessive-Compulsive Disorder (OCD) (0.89), Tic disorders (0.88) and Pervasive developmental disorders (0.81). …”
Publicado 2019
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2122por McInnes, Iain B, Ferraccioli, Gianfranco, D'Agostino, Maria-Antonietta, Le Bars, Manuela, Banerjee, Subhashis, Ahmad, Harris A, Elbez, Yedid, Mease, Philip J“…OBJECTIVE: This post hoc analysis of the phase III Active PSoriaTic Arthritis RAndomizEd TriAl (ASTRAEA) evaluated the effect of baseline body mass index (BMI) on subsequent response to subcutaneous (SC) abatacept in patients with psoriatic arthritis (PsA). …”
Publicado 2019
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2123por Wu, Daidai, Sun, Tiantian, Xie, Rui, Pan, Mengdi, Chen, Xuegang, Ye, Ying, Liu, Lihua, Wu, Nengyou“…Sediments collected from the site 973-4 in the Taixinan Basin on the northern slope of the South China Sea were characterized in terms of total carbon and sulfur, δ(13)C values of total organic carbon (δ(13)C(TIC)), δ(34)S values of chromium reducible sulfur (δ(34)S(CRS)), and foraminiferal oxygen and carbon isotopes. …”
Publicado 2019
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2124“…Parameters time to peak (TtoPk), arrival time (Atm) as well as perfusion parameters A, k and A x k were generated from time-intensity curve (TIC) of CEUS. The correlation analyses of the ICG clearance per unit time (ICGK) and the retention rate at 15 min (ICGR15) with TtoPk, Atm, A, k and A x k were performed, and the diagnostic ability as well as optimal cut-off values of TtoPk and Atm for differentiating patients with ICGR15>10% from ICGR15<10% were analyzed. …”
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2125por Rivas-Ramírez, Paula, Reboreda, Antonio, Rueda-Ruzafa, Lola, Herrera-Pérez, Salvador, Lamas, J. Antonio“…The effect of BK on I(RIL) was precluded by the bradykinin receptor (B(2)R) antagonist HOE-140 (d-Arg-[Hyp(3), Thi(5), d-Tic(7), Oic(8)]BK) but also by diC(8)PIP(2) which prevents PIP(2) depletion when phospholipase C (PLC) is activated. …”
Publicado 2020
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2126por Hammett, Erin K., Fernandez-Carbonell, Cristina, Crayne, Courtney, Boneparth, Alexis, Cron, Randy Q., Radhakrishna, Suhas M.“…CASE PRESENTATION: 1: 16 year old female without significant past medical history presented to the emergency department with 4 days of abnormal behavior, tremors, insomnia, polyphagia, polyuria, and suicidal ideation. 2: 16 year old female with a 4 year history of severe anxiety, OCD, and tic disorder treated with fluoxetine with partial benefit presented with an abrupt and severe worsening of anxiety, OCD and new auditory hallucinations. 3: 19 year old female without significant past medical history presented with a 3 day history of progressively altered behavior, incoherent speech, insomnia, headache, and tangential thoughts. 4: 17 year old female without significant past medical history presented with new onset suicidal ideation, paranoia, confusion, and emotional lability. …”
Publicado 2020
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2127por Conner, Clay, Lager, Tyson W., Guldner, Ian H., Wu, Min-Zu, Hishida, Yuriko, Hishida, Tomoaki, Ruiz, Sergio, Yamasaki, Amanda E., Gilson, Robert C., Belmonte, Juan Carlos Izpisua, Gray, Peter C., Kelber, Jonathan A., Zhang, Siyuan, Panopoulos, Athanasia D.“…We have discovered that (1) cell surface GRP78 (sGRP78) is expressed on iPSCs and is important in reprogramming, (2) sGRP78 promotes cellular functions in both pluripotent and breast cancer cells (3) overexpression of GRP78 in breast cancer cells leads to an induction of a CD24(−)/CD44(+) tumor initiating cell (TIC) population (4) sGRP78(+) breast cancer cells are enriched for stemness genes and appear to be a subset of TICs (5) sGRP78(+) breast cancer cells show an enhanced ability to seed metastatic organ sites in vivo. …”
Publicado 2020
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2128por Cesta, Carolyn E., Öberg, Anna S., Ibrahimson, Abraham, Yusuf, Ikram, Larsson, Henrik, Almqvist, Catarina, D'Onofrio, Brian M., Bulik, Cynthia M., Fernández de la Cruz, Lorena, Mataix-Cols, David, Landén, Mikael, Rosenqvist, Mina A.“…METHODS: A Swedish nationwide register-based cohort study was conducted to disentangle the influence of prenatal androgen exposure from familial confounding in the association between maternal PCOS and offspring attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorders (ASD), and Tourette's disorder and chronic tic disorders (TD/CTD). PCOS-exposed offspring (n = 21 280) were compared with unrelated PCOS-unexposed offspring (n = 200 816) and PCOS-unexposed cousins (n = 17 295). …”
Publicado 2020
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2129“…The clinical severity of tics was evaluated using the Yale Global Tic Severity Scale. …”
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2130por Prabhu, Varun Vijay, Morrow, Sara, Rahman Kawakibi, Abed, Zhou, Lanlan, Ralff, Marie, Ray, Jocelyn, Jhaveri, Aakash, Ferrarini, Isacco, Lee, Young, Parker, Cassandra, Zhang, Yiqun, Borsuk, Robyn, Chang, Wen-I, Honeyman, Joshua N., Tavora, Fabio, Carneiro, Benedito, Raufi, Alexander, Huntington, Kelsey, Carlsen, Lindsey, Louie, Anna, Safran, Howard, Seyhan, Attila A., Tarapore, Rohinton S., Schalop, Lee, Stogniew, Martin, Allen, Joshua E., Oster, Wolfgang, El-Deiry, Wafik S.“…ONC201 was originally discovered as TNF-Related Apoptosis Inducing Ligand (TRAIL)-inducing compound TIC10. ONC201 appears to act as a selective antagonist of the G protein coupled receptor (GPCR) dopamine receptor D2 (DRD2), and as an allosteric agonist of mitochondrial protease caseinolytic protease P (ClpP). …”
Publicado 2020
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2131por Stults-Kolehmainen, Matthew A., Blacutt, Miguel, Bartholomew, John B., Gilson, Todd A., Ash, Garrett I., McKee, Paul C., Sinha, Rajita“…Those with Restless Legs Syndrome, akathisia, tic disorders and exercise dependence all report strong urges to move and relief when it is accomplished. …”
Publicado 2020
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2132“…Using the method of triple-labeling fluorescent immunohistochemistry coupled with confocal microscopy (TIC), we recently studied the interplay among neurons, astrocytes, and microglia in chronic brain hypoperfusion. …”
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2133por Meng, Lingfeng, Tian, Zijian, Long, Xingbo, Diao, Tongxiang, Hu, Maolin, Wang, Miao, Zhang, Wei, Zhang, Yaoguang, Wang, Jianye, He, Yuhui“…Moreover, CIBERSORT analysis of TIC proportions revealed that activated CD4 memory T cells were positively correlated with CASP4 expression. …”
Publicado 2021
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2134por Marceglia, Sara, Prenassi, Marco, Galbiati, Tommaso F., Porta, Mauro, Zekaj, Edvin, Priori, Alberto, Servello, Domenico“…Objective: To investigate the relationship between LFP oscillations and DBS effects on tics and on obsessive compulsive behavior (OCB) comorbidities. …”
Publicado 2021
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2135por Di Stefano, Vincenzo, De Angelis, Maria Vittoria, Montemitro, Chiara, Russo, Mirella, Carrarini, Claudia, di Giannantonio, Massimo, Brighina, Filippo, Onofrj, Marco, Werring, David J., Simister, Robert“…Afterwards, the results were divided depending on the specific insular region affected by the stroke: anterior insular cortex (AIC), posterior insular cortex (PIC) or total insula cortex (TIC). Finally, a review of the clinical correlates associated with each region was performed. …”
Publicado 2021
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2136por Lana, Daniele, Ugolini, Filippo, Nosi, Daniele, Wenk, Gary L., Giovannini, Maria Grazia“…With triple labeling fluorescent immunohistochemistry and confocal microscopy (TIC), it is possible to evaluate and compare quantitatively the morphological and functional alterations of the components of the neuron-astrocyte-microglia triad. …”
Publicado 2021
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2137por He, Xi, Zhang, Qiao, Peng, Nianchun, Hu, Ying, Li, Hong, Chen, Zhengyi, Liu, Ruoyi, Xu, Shujing, Zhang, Miao, He, Juan, Shi, Lixin“…MATERIALS AND METHODS: Data were obtained from the Guiyang subcenter of the Risk Evaluation of cAncers in Chinese diabeTic Individuals: a lONgitudinal (REACTION) study. …”
Publicado 2020
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2138por Li, Enhao, Yang, Xiaobao, Du, Yuzhang, Wang, Guanzheng, Chan, David W., Wu, Di, Xu, Peiqing, Ni, Peihua, Xu, Dakang, Hu, Yiqun“…Accumulating evidence suggests that tumor-infiltrating immune cells (TICs) in the tumor microenvironment (TME) serve as promising therapeutic targets. …”
Publicado 2021
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2139“…We find that consistent information criteria are evidence functions but the MSE minimizing (or efficient) information criteria (e.g., AIC, AICc, TIC) are not. The error properties of the MSE minimizing criteria switch between those of evidence functions and those of Neyman-Pearson tests depending on models being compared.…”
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2140“…METHODS: The gene expression profiles of LUAD patients with complete clinical and follow-up information were downloaded from two public databases, univariate Cox regression and multivariate Cox regression analysis were used to obtain ferroptosis-related genes for constructing the prognos tic risk model, AUC and calibration plot were used to evaluate the predictive accuracy of the FRGS and nomogram. …”
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