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  1. 2621
    “…In this report, we show that tumor-initiating cells (TICs), represented by spheres derived from the MCF7 cell line, exhibit higher intracellular labile iron pool, mitochondrial iron accumulation and are more susceptible to iron chelation. …”
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    Tumor-initiating cells of breast and prostate origin show alterations in the expression of genes related to iron metabolism
  2. 2622
    “…RESULTS: High PD-L1 in tumor cells (TCs) was associated with better OS (p = 0.004), whereas high PD-L1 in tumor-infiltrating immune cells (TICs) was associated with worse OS (p = 0.02). High PD-L1 in TICs correlated with high densities of CD8(+) TICs and CD68(+) TICs, as well as microsatellite instability (p = 0.00000064, 0.00078, and 0.0056), while high PD-L1 in TCs correlated with longer treatment-free interval (TFI) after primary chemotherapy in recurrent cases (p = 0.000043). …”
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    PD-L1 and CD4 are independent prognostic factors for overall survival in endometrial carcinomas
  3. 2623
    “…METHODS: In this study, a novel method for estimating total iron content in soil (TICS) was proposed using harmonic analysis (HA) and back propagation (BP) neural network model. …”
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    Remotely sensed estimation of total iron content in soil with harmonic analysis and BP neural network
  4. 2624
    “…The high TICS was associated with prolonged overall survival (OS), especially in the early-stage LUAD. …”
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    A prognostic and immunotherapeutic predictive model based on the cell-originated characterization of tumor microenvironment in lung adenocarcinoma
  5. 2625
    “…The latent components, which we uncover using tICS, show that the etiology of cervical cancer is age dependent. …”
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    On Exploring Hidden Structures Behind Cervical Cancer Incidence
  6. 2626
    “…Most patients experience tics as a result of the premonitory urges, and after the tics occur, most patients report that the premonitory urges are temporarily relieved. …”
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    Clinical Aspects of Premonitory Urges in Patients with Tourette’s Disorder
  7. 2627
    “…Moreover, knockdown of Jarid2 reduced the proportion of TICs and impaired the tumorigenicity of bladder cancer TICs in vivo. …”
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    Jarid2 is essential for the maintenance of tumor initiating cells in bladder cancer
  8. 2628
    “…The association between the TICS and treatment efficacy was investigated in GSE111177 (androgen deprivation therapy [ADT]) and EGAS00001004050 (ipilimumab). …”
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    Tumor immune contexture predicts recurrence after prostatectomy and efficacy of androgen deprivation and immunotherapy in prostate cancer
  9. 2629
    “…OBJECTIVE: To evaluate the clinical effectiveness of online remote behavior therapy, compared with face-to-face therapy in reducing tics and co-occurring disorders associated with the tics in a sample of youths with Tourette Syndrome. …”
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    A Randomized Controlled Trial Comparing Videoconference vs. Face-to-Face Delivery of Behavior Therapy for Youths With Tourette Syndrome in the Time of COVID-19
  10. 2630
    “…Tourette syndrome is a neuropsychiatric condition characterized by both motor and phonic tics over a period of at least 1 year with the onset in childhood or adolescence. …”
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    Tourette Syndrome and Comorbid Neuropsychiatric Conditions
  11. 2631
    “…These TICs exhibit increased nuclear factor-κB activity. …”
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    Tumour-initiating stem-like cells in human prostate cancer exhibit increased NF-κB signalling
  12. 2632
    “…METHODS: We constructed a new 9-item short version of the TICS covering all nine subdomains and evaluated it in two samples (total N = 685). …”
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    Psychometric properties of an English short version of the Trier Inventory for chronic Stress
  13. 2633
    “…METHODS: We examined human HCCs in settings that selected for tumor formation from functionally defined TICs, and in which the origin of intratumoral ECs from TICs as opposed to host tissues could be clearly distinguished. …”
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    Endothelial cells do not arise from tumor-initiating cells in human hepatocellular carcinoma
  14. 2634
    “…This study aimed to investigate the role of protein kinase B (Akt) pathway in the cytotoxic effect of rolipram on human GBM U87 MG cell line and Tumor-Initiating Cells (TICs) isolated from patient’s GBM specimen. METHODS: TICs were characterized by using flow cytometry and quantitative real-time PCR. …”
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    The Role of Protein Kinase B Signaling Pathway in Anti-Cancer Effect of Rolipram on Glioblastoma Multiforme: An In Vitro Study
  15. 2635
    “…Adult stem cells and tumor-initiating cells (TICs) often employ different mechanisms of DNA damage response (DDR) as compared to other tissue cell types. …”
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    Mammary Stem Cells and Tumor-Initiating Cells Are More Resistant to Apoptosis and Exhibit Increased DNA Repair Activity in Response to DNA Damage
  16. 2636
    “…Tourette syndrome is a common neurodevelopmental disorder defined by multiple motor and phonic tics. Tics in Tourette syndrome resemble spontaneously occurring movements in healthy controls and are therefore sometimes difficult to distinguish from these. …”
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    Increased scale-free and aperiodic neural activity during sensorimotor integration—a novel facet in Tourette syndrome
  17. 2637
    “…Cognitive function was measured using the Telephone Interview for Cognitive Status (TICS), administered in each wave (every 2 years). …”
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    Glaucoma and cognitive function trajectories in a population‐based study: Findings from the health and retirement study
  18. 2638
    “…Tumor initiating cells (TICs) possessing cancer stemness were shown to be enriched after therapy, resulting in the relapse and metastasis of head and neck squamous cell carcinomas (HNC). …”
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    Activation of microRNA-494-targeting Bmi1 and ADAM10 by silibinin ablates cancer stemness and predicts favourable prognostic value in head and neck squamous cell carcinomas
  19. 2639
    “…RESULTS: In aggregate, the distribution of TICS27 scores after ten years of FEM simulation matches the HRS. …”
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    Using dynamic microsimulation to project cognitive function in the elderly population
  20. 2640
    “…INTRODUCTION: Tourette’s syndrome (ST) is a neuropsychiatric disorder that presents with combination of motor and vocal tics for at least one year time.Only few cases of comorbidity with psychotic disorder has been described. …”
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    Gilles de la tourette’s syndrome and psychosis: A family case study
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