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  1. 2641
    “…After haloperidol was discontinued, an exacerbation of tics and the associated behaviors occurred.…”
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    Tourette's disorder and associated complex behaviors: a case report.
  2. 2642
    “…Here, we develop spontaneous preclinical HCC animal models with BDTT to identify the role of BMI1 expressing tumor initiating cells (BMI1(high) TICs) in inducing BDTT. BMI1 overexpression transforms liver progenitor cells into BMI1(high) TICs, which possess strong tumorigenicity and increased trans-intrahepatic biliary epithelial migration ability by secreting lysosomal cathepsin B (CTSB). …”
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    Cathepsin-facilitated invasion of BMI1-high hepatocellular carcinoma cells drives bile duct tumor thrombi formation
  3. 2643
    “…These cells, known as tumor-initiating cells (TICs), would be effective diagnostic tools and valuable therapeutic targets. …”
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    Gene expression profiling and construction of a putative gene regulatory network of bladder cancer tumor-initiating cells
  4. 2644
    “…The median age at first TICS administration was 73 (interquartile range [IQR] 64, 83). …”
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    REDUCED COGNITIVE DECLINE WITH THE APOE ε2/ε2 GENOTYPE IN THE LONG LIFE FAMILY STUDY AND NEW ENGLAND CENTENARIAN STUDY
  5. 2645
    “…BACKGROUND: Deep brain stimulation (DBS) can be an effective therapy for tics and comorbidities in select cases of severe, treatment-refractory Tourette syndrome (TS). …”
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    Image-based analysis and long-term clinical outcomes of deep brain stimulation for Tourette syndrome: a multisite study
  6. 2646
    por Janik, Piotr, Figura, Monika
    Publicado 2016
    “…Tetrabenazine is used in the treatment of chorea, tardive dyskinesia, tics, and dystonia. It rarely causes acute eyeball dystonia and the description of this complication in Gilles de la Tourette syndrome is limited. …”
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    Tetrabenazine-induced oculogyric crisis – a rare complication in the treatment of Gilles de la Tourette syndrome
  7. 2647
    “…BACKGROUND: Tumour-initiating cells (TICs) account for chemoresistance, tumour recurrence and metastasis, and therefore represent a major problem in tumour therapy. …”
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    Inhibition of Cdk5 induces cell death of tumor-initiating cells
  8. 2648
    “…CONCLUSIONS: CBP-beta-catenin signaling promotes stemness via CD133 induction and cell proliferation in TICs. We found a novel functional link between CBP-beta-catenin and PP2A-PTEN-AKT pathway in liver TICs. …”
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    Inhibition of CREB binding protein-beta-catenin signaling down regulates CD133 expression and activates PP2A-PTEN signaling in tumor initiating liver cancer cells
  9. 2649
    “…Thus, the co-expression of SSEA-4 in cancer cells and TICs may have crucial roles in the malignant aggressiveness and prognosis of PC. …”
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    Stage-specific embryonic antigen-4 is a histological marker reflecting the malignant behavior of prostate cancer
  10. 2650
    “…The prognostic value of tumor-infiltrating immune cells (TICs) in solid tumors has been extensively studied. …”
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    The prognostic landscape of tumor-infiltrating immune cells in lung squamous cell carcinoma
  11. 2651
    por Fu, Jing, Peng, Shengkun
    Publicado 2023
    “…We have sorted a subset of tumor-initiating cells (TICs) from the 4T1 cell line based on CD133 positivity by flow cytometry. …”
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    Triple-negative mouse breast cancer initiating cells show high expression of beta1 integrin and increased malignant features
  12. 2652
    “…We demonstrate that Sox2 is required for SCC growth in mouse and human, where it enhances Nrp1/Vegf signaling to promote the expansion of TICs along the tumor-stroma interface. Our findings suggest that distinct transcriptional programs govern self-renewal and long-term growth of TICs and normal skin epithelial stem and progenitor cells. …”
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    SOX2 is a cancer-specific regulator of tumor initiating potential in cutaneous squamous cell carcinoma
  13. 2653
    “…However the study of TICs is hampered by the fact that the identification and culturing of TICs is still a subject of extensive debate. …”
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    What Do We Learn from Spheroid Culture Systems? Insights from Tumorspheres Derived from Primary Colon Cancer Tissue
  14. 2654
    “…Gilles de la Tourette syndrome (GTS) is characterized by multiple motor and vocal tics. Adult-onset cases are rare and may be due to “reactivation” of childhood tics, or secondary to psychiatric or genetic diseases, or due to central nervous system lesions of different etiologies. …”
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    Adult-Onset Gilles de la Tourette Syndrome: Psychogenic or Organic? The Challenge of Abnormal Neurophysiological Findings
  15. 2655
    “…By flow-cytometry analysis of tumor-infiltrating cells (TICs) and lamina propria mononuclear cells (LPMCs) isolated from normal, adjacent mucosa of CRC patients, we showed that CD68/HLA-DRII-expressing TICs and LPMCs expressed M-CSFR-1. …”
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    Macrophages produce and functionally respond to interleukin-34 in colon cancer
  16. 2656
    “…Tourette syndrome (TS) is a neuro-developmental disorder characterized by the occurrence of motor and vocal tics: involuntary, repetitive, stereotyped behaviours that occur with a limited duration, often typically many times in a single day. …”
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    Motor excitability is reduced prior to voluntary movements in children and adolescents with Tourette syndrome
  17. 2657
    por Louis, Elan D, Rao, Ashwini K
    Publicado 2015
    “…RESULTS: The mean TICS score was 35.7 (range 25–39), and mean number of tandem mis-steps was 2.9 (range 0–10). …”
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    Tandem gait performance in essential tremor patients correlates with cognitive function
  18. 2658
    “…The treatment protocol included the following: 1) precast preparation; 2) TICs with treatment; and 3) post-cast treatment to improve the gait pattern. …”
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    Effect of a nonsurgical treatment program on the gait pattern of idiopathic toe walking: a case report
  19. 2659
    “…Three kinds of TICs were negatively related to TEX41 expressions, including macrophages M2, NK cells resting, and macrophages M0. …”
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    Comprehensive Analysis of the Immune Implication of TEX41 in Skin Cutaneous Melanoma
  20. 2660
    “…INTRODUCTION: Tourette’s syndrome is a neuropsychiatric disorder marked by motor and phonic tics frequently associated with psychiatric comorbidities, beginning in childhood. …”
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    Tourette’s syndrome: Alternative approaches to a clinical case refractory to conventional therapy
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