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  1. 2681
    “…Significant interaction was detected between the APOE e4 allele and untreated hypertension (p-int = 0.02 for the TICS; p-int = 0.045 for global score), but not with treated hypertension. …”
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    Interaction between apolipoprotein E genotype and hypertension on cognitive function in older women in the Nurses’ Health Study
  2. 2682
    “…TS follows a developmental time course, in which tics often become increasingly more controlled during adolescence. …”
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    Effects of age on motor excitability measures from children and adolescents with Tourette syndrome
  3. 2683
    “…We discovered the VEGF receptor neuropilin-2 (NRP2) is expressed preferentially on TICs, involved in the genesis of TNBCs and necessary for tumour initiation. …”
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    GLI1 regulates a novel neuropilin-2/α6β1 integrin based autocrine pathway that contributes to breast cancer initiation
  4. 2684
    “…Tumor-initiating cells (TICs) are the culprit leading to CRC chemo-/radiotherapy resistance. …”
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    Enhancement of Sensitivity to Chemo/Radiation Therapy by Using miR-15b against DCLK1 in Colorectal Cancer
  5. 2685
    “…Maintaining the stemness of TICs is critical for the progression of cervical lesions. …”
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    CBP-mediated Wnt3a/β-catenin signaling promotes cervical oncogenesis initiated by Piwil2
  6. 2686
    “…Gilles de la Tourette syndrome (TS) is a neuropsychiatric neurodevelopmental disorder with the cardinal clinical features of motor and phonic tics. Clinical phenomenology can be complex since, besides tics, there are other features including premonitory urges preceding tics, pali-, echo-, and coprophenomena, hypersensitivity to external stimuli, and symptom dependency on stress, attention, and other less well-defined factors. …”
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    Networks in the Field of Tourette Syndrome
  7. 2687
    “…However, these effects have not yet been elucidated: it is unclear whether having comorbid tics with compulsive-like behavior leads to lower quality of life. …”
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    The effects of comorbid Tourette symptoms on distress caused by compulsive-like behavior in very young children: a cross-sectional study
  8. 2688
    “…Finally, we also found that ≥ 70% of lineage negative TICs expressed high amounts of Aire and IL25. CONCLUSION: Thymic explants are an efficient method to obtain functional clonogenic TECs, all mTEC subsets and different TICs Aire(+)IL25(+) with high regenerative capacity. …”
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    Primary explants of the postnatal thymus allow the expansion of clonogenic thymic epithelial cells that constitute thymospheres
  9. 2689
    “…We applied the CIBERSORT computational approach to quantify bulk gene expression profiles and thereby infer the proportions of 22 subsets of tumor-infiltrating immune cells (TICs); 16 kinds of TICs showed differential distributions between the tumor and control tissue samples. …”
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    GEO Data Mining Identifies OLR1 as a Potential Biomarker in NSCLC Immunotherapy
  10. 2690
    “…Every 5-point lower peripandemic TICS-m score was associated with 12% lower odds ratio (OR, 0.88; 95% CI, 0.80, 0.97) of practicing safe hygiene. …”
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    Association of Global Cognitive Function With Psychological Distress and Adherence to Public Health Recommendations During the Coronavirus Disease 2019 Pandemic: The Women’s Health Initiative
  11. 2691
    “…BACKGROUND: Tourette syndrome is a neuropsychiatric disorder characterized by motor and phonic tics. Deficient motor inhibition underlying tics is one of the main hypotheses in its pathophysiology. …”
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    Fine motor skills in adult Tourette patients are task-dependent
  12. 2692
    “…Breast cancer progression and relapse is conceivably due to tumor initiating cells (TICs)/cancer stem cells. EMT (epithelial-mesenchymal-transition)-signaling regulates TICs’ turnover. …”
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    Deficiency of CCN5/WISP-2-Driven Program in breast cancer Promotes Cancer Epithelial cells to mesenchymal stem cells and Breast Cancer growth
  13. 2693
    “…Most worsened symptoms included tics, hyperactivity, rage attacks, obsessions/compulsions, and anxiety. …”
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    Adverse Mental Health Impact of the COVID-19 Lockdown in Individuals With Tourette Syndrome in Italy: An Online Survey
  14. 2694
    “…Cognitive performances were assessed by a Chinese version of the Telephone Interview of Cognitive Status-40 (TICS-40) scale. RESULTS: The patients were divided into a progression group (as determined by decreased TICS-40 scores) and a stable group (as determined by increased or unchanged TICS-40 scores). …”
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    Circulating Neurofilament Light Predicts Cognitive Decline in Patients With Post-stroke Subjective Cognitive Impairment
  15. 2695
    “…Behavioral treatments in these seven consecutively treated adult/adolescent patients with TD included all components of habit reversal treatment, comprehensive behavioral intervention for tics, and exposure with response prevention in some patients. …”
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    Behavior Therapy for the Treatment of Tourette’s Disorder in India: A Patient Series from an Indian General Hospital Psychiatric Unit
  16. 2696
    “…Herein, based on clinical samples, patient‐derived cells (PDCs), and cell lines, it is found that liver cancer cells display stem‐like characteristics upon glutamine shortage due to maintaining the stemness of tumor initiating cells (TICs) and even promoting transformation of non‐TICs into stem‐like cells by glutamine starvation. …”
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    Targeting mTORC2/HDAC3 Inhibits Stemness of Liver Cancer Cells Against Glutamine Starvation
  17. 2697
    “…RESULTS: Compared with controls, COVID-19 patients had lower TICS-40 scores and higher IQCODE scores [TICS-40 median (IQR): 29 (25 to 32) vs. 30 (26 to 33), p < 0.001; IQCODE median (IQR): 3.19 (3.00 to 3.63) vs. 3.06 (3.00 to 3.38), p < 0.001]. …”
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    Post-infection cognitive impairments in a cohort of elderly patients with COVID-19
  18. 2698
    “…Given the identification of human brain tumor-initiating cells (TICs) that initiate and maintain tumor growth while promoting disease progression and relapse in multiple CNS tumors, we investigated whether TICs also drive the growth of human pituitary adenomas. …”
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    The identification of human pituitary adenoma-initiating cells
  19. 2699
    “…BACKGROUND: Tumor microenvironment (TME) and tumor-infiltrating immune cells (TICs) greatly participate in the genesis and development of colon cancer (CC). …”
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    TGFβ1: An Indicator for Tumor Immune Microenvironment of Colon Cancer From a Comprehensive Analysis of TCGA
  20. 2700
    por Wei, Jie, Fang, Dalang, Zhou, Weijie
    Publicado 2021
    “…Finally, the CIBORSORT algorithm was performed to calculate the relative contents of TICs for each LUAD sample, and the correlation analysis between TICs and key genes was used to determine the influence of key genes to the TME. …”
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    CCR2 and PTPRC are regulators of tumor microenvironment and potential prognostic biomarkers of lung adenocarcinoma
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