“…Cancer stem-like cells (CSCs), also termed as tumor-initiating cells (TICs), are increasingly recognized as a critical tumor cell population that drives not only tumorigenesis but also cancer progression, treatment resistance and metastatic relapse. …”
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“…We re­late here re­sults col­lect­ed dur­ing the var­i­ous com­mis­sion­ing and op­er­a­tion pe­ri­ods which led to nom­i­nal per­for­mances and sta­ble beam char­ac­ter­is­tics de­liv­ered to the TBTS. Progress has been made in the laser sys­tem for beam charge and sta­bil­i­ty, in space charge com­pen­sa­tion for emit­tance, in RF com­pres­sion law for en­er­gy and en­er­gy spread. …”
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“…A setup for the in­ves­ti­ga­tion of Co­her­ent Diffrac­tion Ra­di­a­tion (CDR) from tar­gets with var­i­ous con­fig­u­ra­tions as a tool for non-in­va­sive lon­gi­tu­di­nal elec­tron beam pro­file di­ag­nos­tics has been de­signed and in­stalled in the CRM line of the CTF3 [1, 2]. …”
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“…Self-reported questionnaires were used to assess annual volunteering frequency (non volunteering, volunteering <100 h and ≥100 h), and an adapted version of the Telephone Interview for Cognitive Status (TICS) was used to assess memory, mental processing, knowledge, language, and orientation. …”
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“…It has been proposed that cancer recurrence may be attributed to cancer stem cells (CSCs)/tumor-initiating cells (TICs). Previous studies in breast cancer have shown that such cells can be enriched and propagated in vitro by culturing the cells in suspension as mammospheres/tumorspheres. …”
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“…Here we present a novel metabolic network-based approach, MetabOlic Modeling with ENzyme kineTics (MOMENT), which predicts metabolic flux rate and growth rate by utilizing prior data on enzyme turnover rates and enzyme molecular weights, without requiring measurements of nutrient uptake rates. …”
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“…Here we present data that a variable fraction among the circulating tumour cells detected by the Maintrac(® )approach expresses mRNA of the stem cell gene NANOG and of the adhesion molecule vimentin and is capable of forming tumour spheres, a property ascribed to tumour-initiating cells (TICs). PATIENTS AND METHODS: Between ten and 50 circulating epithelial antigen-positive cells detected by the Maintrac approach were selected randomly from each of 20 patients with breast cancer before and after surgery and were isolated using automated capillary aspiration and deposited individually onto slides for expression profiling. …”
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“…OBJECTIVES: The objective was to conduct qualitative research using light hands-on touch energy work with children diagnosed with ASD with focus on the following behaviors: eye contact, appropriate social behavior, verbal tics, motor control and coordination, neural impulses related to the sensory organs, immune system, and ability to learn. …”
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“…IMGT(®), the international ImMunoGeneTics information system(®)(1), (CNRS and Université Montpellier 2) is the global reference in immunogenetics and immunoinformatics. …”
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“…Many studies have investigated environmental factors that might contribute to the onset and severity of tics and associated comorbidities such as obsessive compulsive disorder (OCD) and attention deficit hyperactive disorder (ADHD). …”
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“…Along with the Immuno Polymorphism Database-IMunoGeneTics/human leukocyte antigen (IPD-IMGT/HLA) database, a collection of databases for curated sequences of immune importance has been developed. …”
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“…An important premise is that participants need to repeatedly experience stimulus–reward pairings to obtain these effects (e.g., Awh, Belopolsky & Theeuwes, Trends in Cognitive Sciences 16:437–443, 2012, 10.1016/j.tics.2012.06.010). This idea is based on associative learning theories (e.g., Pearce & Bouton, Annual Review of Psychology 52:111–139, 2001) that suggest that exposure to stimulus–reward pairings leads to the formation of stimulus–reward associations, and a transfer of salience of the reward to the neutral stimulus. …”
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“…Trial outcome: Primary outcome is feasibility of recruitment and compliance; secondary outcomes include safety (cerebral or systemic bleeding, falls, death), efficacy (recurrent cerebral and cardiac vascular events, cognition on TICS, Trails B) and tolerability. SUMMARY: LACI-2 will determine feasibility, tolerability and provide outcome rates to power a large phase 3 trial to prevent progression of cerebral small vessel disease.…”
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“…Patients who received SCRT had poorer prognostic tumor characteris-tics. Median follow-up was 29.6 months (95% CI: 19.6-39.5 months). …”
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“…We conducted race/ethnicity-stratified linear regression models where cognitive functioning, measured using the 35-point Telephone Interview Cognitive Screen (TICS), was regressed on three neighborhood characteristics—cleanliness, safety, and social cohesion. …”
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“…This pedigree spans six generations and includes 122 members, 85 of whom were individually interviewed, and 53 of whom were diagnosed as ‘cases’ (consisting of 28 with definite or probable TS, 20 with chronic multiple tics [CMT], and 5 with obsessive-compulsive behaviors [OCB]). …”
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“…Dysfunction in these brain areas can result in different forms of semivoluntary movement as the borderland of voluntary and involuntary movement where a person may experience a disordered sense of will or agency, and thus the movement is experienced as unexpected and involuntary, for an otherwise voluntary-appearing movement. Tics, functional movement disorders, stereotypies, perseveration, compulsions, utilization behaviors, and motor mannerism have been described elsewhere in the context of psychoses, and are often mistaken for each other. …”
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“…The IgM anti-ganglioside antibodies increased the risk of tics and positive symptoms (p = 0.0345, p = 0.0263, respectively), the anti-glutamic acid decarboxylase particle of paresis (p = 0.0074), and anti-neuroendothelium of mutism (p = 0.0361). …”
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“…Tourette syndrome (TS) is a neurodevelopmental movement disorder characterized by multiple motor and vocal tics. In this study, we used a TS rat model induced by 3,3′-iminodipropionitrile (IDPN) and aimed to investigate the expression change of Syntaxin 1A (STX1A). …”
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