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Mostrando 181 - 200 Resultados de 2,825 Para Buscar '"TK"', tiempo de consulta: 0.27s Limitar resultados
  1. 181
    “…TK1-overexpressed and TK-1-silenced BMSCs of SLE were conducted and apoptosis and cell cycle were measured with flow cytometry. …”
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    Identification of Novel Immune Cell-Relevant Therapeutic Targets and Validation of Roles of TK1 in BMSCs of Systemic Lupus Erythematosus
  2. 182
    “…Mechanistically, through FISH experiments, luciferase reporter experiments, and RIP experiments, we proved that CASC9 regulated the expression of TK1 by adsorbing miR-195-5p, thereby exerting an oncogenic effect in bladder cancer. …”
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    NF-κB-Activated lncRNACASC9 Promotes Bladder Cancer Progression by Regulating the TK1 Expression
  3. 183
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    Structural analysis of cannabinoids against EGFR-TK leads a novel target against EGFR-driven cell lines
  4. 184
    “…TK1 was overexpressed in glioma compared with normal samples, and patients with elevated expression of TK1 had poor overall survival. …”
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    Multi-Omics Integration Analysis of TK1 in Glioma: A Potential Biomarker for Predictive, Preventive, and Personalized Medical Approaches
  5. 185
    “…While a previous in vivo genotoxicity study was inconclusive, in vitro results demonstrated that C17-SAMT induced an increase in micronucleus formation in human lymphoblastoid TK6 cells at concentrations of 0.87 µM and 1.74 µM. …”
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    An Evaluation of the Cytotoxic and Genotoxic Effects of the Marine Toxin C17-SAMT in Human TK6 and HepaRG Cell Lines
  6. 186
    “…RESULTS: The specific gene expression of Cre and HSV-tk in HLECs is activated by the LEP503 promoter. …”
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    Using HSV-TK/GCV suicide gene therapy to inhibit lens epithelial cell proliferation for treatment of posterior capsular opacification
  7. 187
    “…TK0471/TrmBL2 binds to both coding and intergenic regions and represses transcription when bound to the promoter region. …”
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    Histone and TK0471/TrmBL2 form a novel heterogeneous genome architecture in the hyperthermophilic archaeon Thermococcus kodakarensis
  8. 188
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    Modification of genetic regulation of a heterologous chitosanase gene in Streptomyces lividans TK24 leads to chitosanase production in the absence of chitosan
  9. 189
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    Evaluation of bioactive compounds produced by Nocardia levis MK-VL_113 & Streptomyces tendae TK-VL_333 for cytotoxic activity
  10. 190
    “…Each received 2-apical and 2-basal 0.5 ml injections of AdV-tk for a total of 1×10(11) vp followed by 14 days of prodrug. …”
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    Intraprostatic distribution and long term follow-up after AdV-tk immunotherapy as neoadjuvant to surgery in patients with prostate cancer
  11. 191
    “…In contrast, proliferative HepaRG® cells could engraft TK-NOG mouse liver but could differentiate only toward biliary-like cells. …”
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    The human hepatic cell line HepaRG as a possible cell source for the generation of humanized liver TK-NOG mice
  12. 192
    “…In a companion article, a genomic biomarker was developed in human TK6 cells to classify chemicals as genotoxic or nongenotoxic. …”
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    Integration of metabolic activation with a predictive toxicogenomics signature to classify genotoxic versus nongenotoxic chemicals in human TK6 cells
  13. 193
    “…Phylogenetic and sequence analyses showed that TK0512 and its homologues in Thermococcaceae represent new members in the archaemetzincins family, which we named AMZ-tk. …”
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    A Zinc-Dependent Protease AMZ-tk from a Thermophilic Archaeon is a New Member of the Archaemetzincin Protein Family
  14. 194
    “…The results indicated that the TK model must show high goodness-of-fit to be a useful tool for comparing treatments. …”
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    A new TK model approach to assess the effect of migration on copper toxicokinetics in inbred populations of the flour beetle, Tribolium castaneum
  15. 195
    “…In general, the compounds were more active in TK6 cells than they were in blood lymphocytes. Only 1 μM selenous acid increased the frequency of binucleated cells containing micronuclei (BNMN) in blood lymphocytes, while all three selenium compounds increased BNMN in TK6 cells. …”
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    Genotoxic and antigenotoxic properties of selenium compounds in the in vitro micronucleus assay with human whole blood lymphocytes and tk6 lymphoblastoid cells
  16. 196
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    Author Correction: Induction of micronuclei by four cytostatic compounds in human hematopoietic stem cells and human lymphoblastoid TK6 cells
  17. 197
    “…In this study, for the first time, we evaluated the genotoxicity induced by lead in human lymphoblastoid TK6 cells. MATERIAL/METHODS: The TK6 cells were incubated with various concentrations of Pb(Ac)(2) for 6 h, 12 h, or 24 h. …”
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    Lead Induces Genotoxicity via Oxidative Stress and Promoter Methylation of DNA Repair Genes in Human Lymphoblastoid TK6 Cells
  18. 198
    “…RESULTS: To evaluate the role of NER sub-pathways on the cytotoxic effects of mutagens, we disrupted XPC and CSB to selectively inactivate GG-NER and TC-NER, respectively, in human lymphoblastoid TK6 cells, a standard cell line used in genotoxicity studies. …”
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    Comparative study of cytotoxic effects induced by environmental genotoxins using XPC- and CSB-deficient human lymphoblastoid TK6 cells
  19. 199
    “…It is believed that this work would be giving a reference for developing anti-cancer drugs targeted EGFR-TK.…”
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    Novel 4-arylaminoquinazolines bearing N,N-diethyl(aminoethyl)amino moiety with antitumour activity as EGFR(wt)-TK inhibitor
  20. 200
    “…Here, we provide further evidence that PHF1 co-localizes with H3t in testis and its Tudor domain preferentially binds to H3tK27me3 over canonical H3K27me3 in vitro. Our complex structures of the Tudor domains of PHF1 and PHF19 with H3tK27me3 shed light on the molecular basis for preferential recognition of H3tK27me3 by PHF1 and PHF19 over canonical H3K27me3, implicating that H3tK27me3 might be a physiological ligand of PHF1/19.…”
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    Structural basis for histone variant H3tK27me3 recognition by PHF1 and PHF19
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