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201por Giroud, Paul, Renaudineau, Sarah, Gudefin, Laura, Calcei, Alexandre, Menguy, Thierry, Rozan, Caroline, Mizrahi, Jacques, Caux, Christophe, Duong, Vanessa, Valladeau-Guilemond, Jenny“…Here, we have identified MerTK among TAM-R as the major marker of both human M2 macrophages and tolerogenic dendritic cells (DC). …”
Publicado 2020
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202“…Input parameters were utilized from the prospective TK-Study. To investigate the economic impact of MRM, overall costs in € and outcomes of MRM in quality-adjusted life years (QALYs) were estimated. …”
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203“…Sandwich Elisa, biotin-labeled antibody kit was used for TK1, and other tumor markers were measured using electro-chemiluminescence. …”
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204“…We identified an 81-gene transcriptomic biomarker of histone deacetylase inhibitors (HDACi) using whole transcriptome data sets of TK6 human lymphoblastoid cells generated by Templated Oligo-Sequencing (TempO-Seq) after 4 h of exposure to 20 reference compounds (10 HDACi and 10 non-HDACi) [1]. …”
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205por Deng, Meng-Meng, Sun, Ya-Wei, Ding, Chen-Meng, Xu, Xi-Ya, Guo, Zi-Yi, Han, Zi-Wei, Lv, Chen-Zhe, Qi, Jiang-Kun, Li, Yong-Tao, Yang, Xia, Yu, Lin-Yang, Chen, Lu“…Here, PRV ΔgE/TK/US3 strain was generated by deleting US3 gene based on PRV ΔgE/TK strain using the same method. …”
Publicado 2022
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206por Perez-Diaz, Noelia, Hoffman, Ewelina, Clements, Julie, Cruickshank, Rebecca, Doherty, Ann, Ebner, Daniel, Elloway, Joanne, Fu, Jianan, Kelsall, Joanne, Millar, Val, Saib, Ouarda, Scott, Andrew, Woods, Ian, Hutter, Victoria“…TK6 were adapted to CDSR supplemented medium either via direct or gradual transition reducing from 10% v/v FBS to 0% v/v FBS. …”
Publicado 2023
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207por Bitter, Eliza E., Skidmore, Jonathan, Allen, Carolyn I., Erickson, Rachel I., Morris, Rachel M., Mortimer, Toni, Meade, Audrey, Brog, Rachel, Phares, Tim, Townsend, Michelle, Pickett, Brett E., O’Neill, Kim L.“…Here, we evaluate potential pathogenic effects of elevated TK1 expression by comparing HCC 1806 to HCC 1806 TK1-knockdown cancer cells (L133). …”
Publicado 2023
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208por Quack, Thomas, Knobloch, Jürgen, Beckmann, Svenja, Vicogne, Jérome, Dissous, Colette, Grevelding, Christoph G.“…The Src-like tyrosine-kinase SmTK3 of Schistosoma mansoni is expressed in the gonads, and its pharmacological inhibition reduces mitogenic activity and egg production in paired females in vitro. …”
Publicado 2009
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209por Zarogoulidis, P., Matthaios, D., Iordanidis, A., Zervas, V., Mitrakas, A., Kouliatsis, G., Zarogoulidis, K.“…He refused to be treated with neither chemotherapy nor radiotherapy, but due to EGFR overexpression, treatment with TK inhibitor was suggested. Fine needle aspiration biopsy is commonly used to identify metastasis to the mediastinum. …”
Publicado 2011
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210por Kan, Shifu, Wang, Yuhang, Sun, Lili, Jia, Peng, Qi, Yanxin, Su, Jiaqiang, Liu, Lei, Yang, Guohua, Liu, Liming, Wang, Zhuoyue, Wang, Jinhui, Liu, Guangchen, Jin, Ningyi, Li, Xiao, Ding, Zhuang“…Vaccinia Tian Tan (VTT) was attenuated by deletion of the TC7L-TK2L and TA35R genes to generate MVTT3. The mutant was generated by replacing the open reading frames by a gene encoding enhanced green fluorescent protein (EGFP) flanked by loxP sites. …”
Publicado 2012
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211por Hirata, Azumi, Hori, Yuki, Koga, Yuichi, Okada, Jun, Sakudo, Akikazu, Ikuta, Kazuyoshi, Kanaya, Shigenori, Takano, Kazufumi“…BACKGROUND: Tk-SP is a member of subtilisin-like serine proteases from a hyperthermophilic archaeon Thermococcus kodakarensis. …”
Publicado 2013
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212“…A lipopeptide biosurfactant produced by Bacillus natto TK-1 has a strong surface activity. The biosurfactant was found to be an anti-adhesive agent against several bacterial strains, and also showed a broad spectrum of antimicrobial activity. …”
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213por de Melo, Suely Maymone, Bittencourt, Simone, Ferrazoli, Enéas Galdini, da Silva, Clivandir Severino, da Cunha, Flavia Franco, da Silva, Flavia Helena, Stilhano, Roberta Sessa, Denapoli, Priscila Martins Andrade, Zanetti, Bianca Ferrarini, Martin, Priscila Keiko Matsumoto, Silva, Leonardo Martins, dos Santos, Adara Aurea, Baptista, Leandra Santos, Longo, Beatriz Monteiro, Han, Sang Won“…AT-MSCs were prepared using a mechanical protocol to avoid contamination with animal protein and transduced with HSV-Tk via a lentiviral vector. The U-87 glioblastoma cells cultured with AT-MSC-HSV-Tk died in the presence of 25 or 50 μM ganciclovir (GCV). …”
Publicado 2015
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214por Rebets, Yuriy, Tsolis, Konstantinos C., Guðmundsdóttir, Elísabet Eik, Koepff, Joachim, Wawiernia, Beata, Busche, Tobias, Bleidt, Arne, Horbal, Liliya, Myronovskyi, Maksym, Ahmed, Yousra, Wiechert, Wolfgang, Rückert, Christian, Hamed, Mohamed B., Bilyk, Bohdan, Anné, Jozef, Friðjónsson, Ólafur, Kalinowski, Jörn, Oldiges, Marco, Economou, Anastassios, Luzhetskyy, Andriy“…Here we report the development of a robust gene deletions system for Streptomyces lividans TK24 based on a BAC library combined with the λ-Red recombination technique. …”
Publicado 2018
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215por Cho, Eunnara, Buick, Julie K., Williams, Andrew, Chen, Renxiang, Li, Heng‐Hong, Corton, J. Christopher, Fornace, Albert J., Aubrecht, Jiri, Yauk, Carole L.“…The 64 genes were previously derived from whole transcriptome DNA microarray profiles of 28 reference agents (14 DDI and 14 non‐DDI) after 4 h treatments of TK6 human lymphoblastoid cells. To broaden the applicability of TGx‐DDI, we tested the biomarker using quantitative RT‐PCR (qPCR), which is accessible to most molecular biology laboratories. …”
Publicado 2018
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216por Dührsen, Lasse, Hartfuß, Sophie, Hirsch, Daniela, Geiger, Sabine, Maire, Cecile L., Sedlacik, Jan, Guenther, Christine, Westphal, Manfred, Lamszus, Katrin, Hermann, Felix G., Schmidt, Nils OleEnlace del recurso
Publicado 2019
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217por Zhu, Yueqiang, Chen, Chao, Cao, Ziyang, Shen, Song, Li, Laisheng, Li, Dongdong, Wang, Junxia, Yang, Xianzhu“…Methods: In this study, we synthesized red light-responsive, amphiphilic mPEG bridged to the photosensitizer Ce6 via a thioketal (TK) bond (mPEG-TK-Ce6), which was then used to achieve the PEGylation of polylactide (PLA)-based nanoparticles encapsulating the Pt(IV) prodrug. …”
Publicado 2019
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218por LIN, Jinxin, LI, Zhaolong, FENG, Zhihua, FANG, Zhou, CHEN, Jianghua, CHEN, Wengzhi, LIANG, Wangwang, CHEN, Qi“…Therefore, in this study, we generated a PRV-∆gC\gE∆TK strain with defects in gC, gE, and TK of PRV. …”
Publicado 2020
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219por Mattman, Andre, Nadeau, Elizabeth, Mezei, Michelle M., Cresswell, Mark, Zhao, Sida, Bosdet, Taryn, Sin, Don D., Guenette, Jordan A., Dupuis, Isabelle, Allin, Emily, Clarke, David C.Enlace del recurso
Publicado 2022
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220por Yan, Shijun, Huang, Baicheng, Bai, Xiaofei, Zhou, Ying, Guo, Linghua, Wang, Tongyan, Shan, Yihong, Wang, Yuzhou, Tan, Feifei, Tian, Kegong“…The vaccination of rHN1201(TK−/gE−/gI−/11k−/28k−) could elicit an earlier and higher level of gB antibody, and the neutralizing antibodies elicited by rHN1201(TK−/gE−/gI−/11k−/28k−) were effective against both PRV classical and variant strains. …”
Publicado 2022
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