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2641“…The 16S rRNA gene and genome GTDB-Tk taxonomic annotation showed that it was a novel strain of Enterobacter hormaechei, and it was named E. hormaechei Z129. …”
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2642“…The organic matter content and AK content of the Loess soil was significantly higher than in the Aeolian soil, and the pH was closer to neutral. However, the TK content, TP content, and AP content of the Aeolian soil were slightly higher than in the Loess soil, the pH was higher, and it was alkaline. (2) After controlling the light and temperature, with all other external factors consistent, the daily variation trend of P(N), T(r), and G(s) in the leaves of H. rhamnoides plants growing in the two different soils were basically the same. …”
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2643“…Additionally, the phylogenomic analysis of more than 500 genomes of the class Opitutae, encompassing a majority of uncultivated bacteria and a few type strains, was performed using the Genome Taxonomic Database toolkit (GTDB-Tk) to present adequate resolution of the taxonomy. …”
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2644por Quarato, Emily R., Salama, Noah A., Li, Allison J., Smith, Charles O., Zhang, Jane, Kawano, Yuko, McArthur, Matthew, Liesveld, Jane L., Becker, Michael W., Elliott, Michael R., Eliseev, Roman A., Calvi, Laura M.“…Transcriptional analysis showed that MSCs possess the necessary receptors and internal processing machinery to conduct efferocytosis, with Axl and Tyro3 serving as the main receptors, while MerTK was not expressed. Moreover, the expression of these receptors was modulated by efferocytic behavior, regardless of apoptotic target. …”
Publicado 2023
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2645“…Sagittal parameters were obtained on the whole spinal lateral radiograph, including T1‐T12 slope (T1S‐T12S), Cobb angle (CA) of the functional units of the thoracic spine, thoracic kyphosis (TK), lumbar lordosis (LL), sacral slope (SS), pelvic tilt (PT), PI, the ratio of PT to PI (PT/PI), PI minus LL mismatch (PI‐LL), sagittal vertical axis (SVA). …”
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2646“…Such favorable metabolic polarization enhanced cell‐surface MerTK levels and the phagocytic uptake of apoptotic cells. …”
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2647por Ghirardini, Maria Pia, Carli, Marco, del Vecchio, Nicola, Rovati, Ariele, Cova, Ottavia, Valigi, Francesco, Agnetti, Gaia, Macconi, Martina, Adamo, Daniela, Traina, Mario, Laudini, Francesco, Marcheselli, Ilaria, Caruso, Nicolò, Gedda, Tiziano, Donati, Fabio, Marzadro, Alessandro, Russi, Paola, Spaggiari, Caterina, Bianco, Marcella, Binda, Riccardo, Barattieri, Elisa, Tognacci, Alice, Girardo, Martina, Vaschetti, Luca, Caprino, Piero, Sesti, Erika, Andreozzi, Giorgia, Coletto, Erika, Belzer, Gabriele, Pieroni, Andrea“…We proposed the hypothesis that these differences may be due to the likelihood that in Southern Italy the erosion of TK on wild vegetables is taking place more slowly, and also to the likelihood that Southern Italians' have a higher appreciation of wild vegetables that have a strong and bitter taste. …”
Publicado 2007
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2648“…Patients with primary operable cancer had significantly higher serum thymidine kinase levels over normal controls (P less than 0.01). Mean serum TK in patients with inflammatory gastrointestinal diseases was similar to normal controls but significantly less than both patients with primary operable breast cancer and patients with systemic breast cancer. …”
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2649por Pestalozzi, B. C., McGinn, C. J., Kinsella, T. J., Drake, J. C., Glennon, M. C., Allegra, C. J., Johnston, P. G.“…In contrast to TS, a 4-fold difference in thymidine kinase (TK) was detected between G0/G1 and S-phase cells in exponentially growing MCF-7 cells. …”
Publicado 1995
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2650por Walton, M. I., Mitchell, F., Aherne, G. W., Medlow, C. J., Boyle, F. T., Jackman, A. L.“…ZD9331 shows anti-tumour activity by both 24-h infusion and bolus administration in the murine thymidine kinase-deficient (TK -/-) lymphoma L5178Y. In view of the history of renal toxicity with some earlier TS inhibitors and the possible therapeutic use of bolus ZD9331, we have examined the effects of bolus ZD9331 dose and route of administration on plasma and kidney pharmacokinetics and renal function in mice. …”
Publicado 1998
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2651por Xiong, Weidong, Candolfi, Marianela, Liu, Chunyan, Muhammad, A. K. M. Ghulam, Yagiz, Kader, Puntel, Mariana, Moore, Peter F., Avalos, Julie, Young, John D., Khan, Dorothy, Donelson, Randy, Pluhar, G. Elizabeth, Ohlfest, John R., Wawrowsky, Kolja, Lowenstein, Pedro R., Castro, Maria G.“…We have developed a conditional cytotoxic/immunotherapeutic approach using adenoviral vectors (Ads) encoding the immunostimulatory cytokine, human soluble fms-like tyrosine kinase 3 ligand (hsFlt3L) and the conditional cytotoxic molecule, i.e., Herpes Simplex Type 1- thymide kinase (TK). This therapy triggers an anti-tumor immune response that leads to tumor regression and anti-tumor immunological memory in intracranial rodent cancer models. …”
Publicado 2010
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2652por Chen, Zhi Heng, Huang, Shou Qing, Wang, Yande, Yang, Ai Zhen, Wen, Jian, Xu, Xiao Hong, Chen, Yan, Chen, Qu Bo, Wang, Ying Hong, He, Ellen, Zhou, Ji, Skog, Sven“…We conclude that serological TK1 protein concentration is a reliable marker for risk assessment of pre/early cancerous progression.…”
Publicado 2011
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2653por Lassen, Tina Harmer, Frederiksen, Hanne, Jensen, Tina Kold, Petersen, Jørgen Holm, Joensen, Ulla N., Main, Katharina M., Skakkebaek, Niels E., Juul, Anders, Jørgensen, Niels, Andersson, Anna-Maria“…Citation: Lassen TH, Frederiksen H, Jensen TK, Petersen JH, Joensen UN, Main KM, Skakkebaek NE, Juul A, Jørgensen N, Andersson AM. 2014. …”
Publicado 2014
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2654por Changsom, Don, Lerdsamran, Hatairat, Wiriyarat, Witthawat, Chakritbudsabong, Warunya, Siridechadilok, Bunpote, Prasertsopon, Jarunee, Noisumdaeng, Pirom, Masamae, Wanibtisam, Puthavathana, Pilaipan“…Influenza neuraminidase (NA) proteins expressed in TK(−) cells infected with recombinant vaccinia virus carrying NA gene of highly pathogenic avian influenza H5N1 virus or 2009 pandemic H1N1 (H1N1pdm) virus were characterized for their biological properties, i.e., cell localization, molecular weight (MW), glycosylation and sialidase activity. …”
Publicado 2016
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2655por Jensen, Tina Kold, Frederiksen, Hanne, Kyhl, Henriette Boye, Lassen, Tina Harmer, Swan, Shanna H., Bornehag, Carl-Gustaf, Skakkebaek, Niels E., Main, Katharina M., Lind, Dorte Vesterholm, Husby, Steffen, Andersson, Anna-Maria“…CONCLUSION: We found no significant trends towards shorter AGD in boys with higher phthalates exposures in this low exposed Danish population. CITATION: Jensen TK, Frederiksen H, Kyhl HB, Lassen TH, Swan SH, Bornehag CG, Skakkebaek NE, Main KM, Lind DV, Husby S, Andersson AM. 2016. …”
Publicado 2015
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2656por Lassen, Tina Harmer, Frederiksen, Hanne, Kyhl, Henriette Boye, Swan, Shanna H., Main, Katharina M., Andersson, Anna-Maria, Lind, Dorte Vesterholm, Husby, Steffen, Wohlfahrt-Veje, Christine, Skakkebæk, Niels E., Jensen, Tina Kold“…CITATION: Lassen TH, Frederiksen H, Kyhl HB, Swan SH, Main KM, Andersson AM, Lind DV, Husby S, Wohlfahrt-Veje C, Skakkebæk NE, Jensen TK. 2016. Prenatal triclosan exposure and anthropometric measures including anogenital distance in Danish infants. …”
Publicado 2016
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2657“…First-generation EGFR/HER-TKIs, binding competitively and reversibly to the ATP-binding site of the EGFR TK domain, show a significant breakthrough treatment in selected NSCLC patients with activating EGFR mutations (actEGFRm) EGFR(L858R) and EGFR(Del19), in terms of safety, efficacy, and quality of life. …”
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2658“…CONCLUSIONS: The application of NH(4) (+):NO(3) (−) (10:90) increased rbcL, rbcS, FBA, FBPase and TK expression and/or activities, enhanced photosynthesis, carbohydrate accumulation and improved the tolerance of mini Chinese cabbage seedlings to LL. …”
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2659por Sassi, Celeste, Nalls, Michael A., Ridge, Perry G., Gibbs, Jesse R., Lupton, Michelle K., Troakes, Claire, Lunnon, Katie, Al-Sarraj, Safa, Brown, Kristelle S., Medway, Christopher, Lord, Jenny, Turton, James, Bras, Jose, Blumenau, Sonja, Thielke, Mareike, Josties, Christa, Freyer, Dorette, Dietrich, Annette, Hammer, Monia, Baier, Michael, Dirnagl, Ulrich, Morgan, Kevin, Powell, John F., Kauwe, John S., Cruchaga, Carlos, Goate, Alison M., Singleton, Andrew B., Guerreiro, Rita, Hodges, Angela, Hardy, John“…We identified 3 likely pathogenic mutations in CSF1R TK domain (p.L868R, p.Q691H, and p.H703Y) in our discovery and validation cohort, composed of 465 AD and mild cognitive impairment (MCI) Caucasian patients from the United Kingdom. …”
Publicado 2018
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2660por Deichmann, Steffen, Bolm, Louisa Romina, Honselmann, Kim Christin, Wellner, Ulrich Friedrich, Lapshyn, Hryhoriy, Keck, Tobias, Bausch, Dirk“…All LPD procedures were performed by one specialised pancreatic surgeon (TK). Patients were matched 1 : 1 for age, sex, BMI, ASA, histological diagnosis, pancreatic texture and portal venous resection (PVR). …”
Publicado 2018
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