“…To examine the relevant regulation of PCAN1, pGL(3)-p2.6kb was transfected into the prostate cancer cell line LNCaP, which was treated with R1881 (10(−7)∼10(−9) mol/l), 17β-estradiol (17β-E(2), 10(−7)∼10(−9) mol/l), all-trans-retinoic acid (all-trans-RA, 10(−5)∼10(−7) mol/l) or 9-cis-retinoic acid (9-cis-RA, 10(−5)∼10(−7) mol/l), and eukaryotic expression plasmids of NKX3.1, p53, Sp1, Pten, PPARγ or cEBPα were cotransfected with pGL(3)-p2.6kb into LNCaP cells. pRL-TK, a Renilla luciferase reporter vector, was cotransfected into all the transfection lines as an internal control. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In turkeys, the mg/PCU(Tk) decreased by 1%, whereas the nDDDvetCA/1,000 turkey-days and the nDDDvetCA/PCU increased by 1 and 5%, respectively. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The loss of C3aR expression also attenuated an increase in the expression of the efferocytosis-related protein, MerTK, whose transcript was upregulated ~ 2.5-fold in the Smarca5 mutant cerebellum at P10. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…By sequence similarity analysis and functional assays from the species Streptomyces lividans TK23, S. coelicolor A3(2) and S. glaucescens GLA.O, first hints for a widespread lack of MalP and presence of AmlE in the class Actinobacteria were given. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In line with the above hypothesis that monocytes and macrophages are differentially regulated by statins, the CD14/CD16-, merTK-, CX(3)CR1-, or CD163-expression (M2-macrophage-related) correlated inversely to the cytokine production. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The biomarker, developed for use in human TK6 cells, is a panel of 64 genes that accurately classifies chemicals as DDI or non-DDI. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Additionally, single nucleotide variations (SNVs) were identified via GenomeAnalysisTK and SNV risk was assessed via VarioWatch. Mutant genes with a high frequency and risk were validated by RT-PCR analyses. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The program is built using the TCL/TK programming language, which can be compiled via R software libraries (tcltk, tkrplot, tcltk2). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…It was a target of tyrosine kinase (TK) inhibitors emerged in the therapy of diverse cancers. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…IgE cross-linking on human monocytes with polyclonal antibodies to mimic formation of immune complexes induced upregulation of co-stimulatory (CD40, CD80, CD86), and reduced expression of regulatory (CD163, CD206, MerTK) monocyte markers. Cross-linking and tumour antigen-specific IgE antibody-dependent cellular cytotoxicity (ADCC) of cancer cells by cancer patient-derived monocytes triggered release of pro-inflammatory mediators (TNFα, MCP-1, IL-10, CXCL-10, IL-1β, IL-6, IL-23). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…HOW TO CITE THIS ARTICLE: Daga MK, Kumar L, Mawari G, Kumar N, Singh S, Mishra TK. Adrenomedullin and Its Possible Role in Improved Survival in Female Patients with Sepsis: A Study in the South East Asian Region. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Another study found that human herpesvirus 1 thymidine kinase (HHV-1 TK) protein disrupts spermatogenesis by creating immature sperm and accelerating apoptotic cell death in rodent. …”
Enlace del recurso
Enlace del recurso

“…METHODS: A total of 24 patients with AS and thoracolumbar kyphosis (TK) who were admitted to the First Affiliated Hospital of Xinjiang Medical University between 2008 and 2019 were enrolled in this study. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The images were registered to a study-specific template using a longitudinal pipeline based on full tensor information in DTI-TK. Voxel-based analysis was performed using tract-based spatial statistics (TBSS). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The transcription of the only immediate-early gene IE180 in the brain was significantly inhibited by kaempferol, leading to the decreased transcriptional levels of the early genes (EPO and TK). The expression of latency-associated transcript (LAT) was also inhibited in the brain, which suggested that kaempferol could inhibit PRV latency. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Images were captured for the cytokinesis-block micronucleus (CBMN) assay across three laboratories using methyl methanesulphonate (1.25–5.0 μg/mL) and/or carbendazim (0.8–1.6 μg/mL) exposures to TK6 cells. Human-scored image sets were assembled and used to train and test the classification abilities of the “DeepFlow” neural network in both intra- and inter-laboratory contexts. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…A segregating population from a cross between the sunflower resistant line DEB2, carrying Or(Deb2), and a susceptible line was phenotyped for broomrape resistance in four experiments, including different environments and two broomrape races (F(GV) and G(TK)). This population was also densely genotyped with microsatellite and SNP markers, which allowed locating Or(Deb2) within a 0.9 cM interval in the upper half of Chromosome 4. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The data is available at https://data-access.cesgo.org/index.php/s/V97GXxOS66NqTkZ. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at (10.1186/s12864-022-08429-4).…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…RESULTS: The nine compounds targeting CAPN2, EPHX2, MDK, MerTK/FLT3, or SYK proteins were profiled in 46 to 47 primary GPCR binding assays. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Several aspects of the TME can contribute to treatment resistance in NSCLC, including through the activation of Tyro3, Axl, MerTK (TAM) receptors which are essential pleiotropic regulators of immune homeostasis. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso