Mostrando 41 - 60 Resultados de 2,825 Para Buscar '"TK"', tiempo de consulta: 0.20s Limitar resultados
  1. 41
    “…We initially selected 6 fluoropyrimidine metabolism-related genes (DPYD, ORPT, TYMS, TYMP, TK1, and TK2) and 3 radiotherapy response-related genes (GLUT1, HIF-1 α, and HIF-2 α) as targets for gene expression identification in 60 LARC cancer specimens. …”
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  2. 42
    por Bianchi, Giovanni
    Publicado 2013
    “…A new CMS tracker is scheduled to become operational for the LHC Phase 2 upgrade in the early 2020's. tkLayout is a software package developed to create 3d models for the design of the CMS tracker and to evaluate its fundamental performance figures. …”
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    “…OBJECTIVE: The efficiency of HSV-tk/GCV system is not high because of insufficient gene transfer and incompletely initiative of host antineoplastic potency. …”
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  6. 46
    “…MerTK targeted shRNA completely prevented intracranial and subcutaneous glioma growth further delineating the impact of MerTK inhibition on glioblastoma. …”
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    “…SUMMARY: The Genome Taxonomy Database Toolkit (GTDB-Tk) provides objective taxonomic assignments for bacterial and archaeal genomes based on the GTDB. …”
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    “…It is well-established that the secondary active transporters Glt(Tk) and Glt(Ph) catalyze coupled uptake of aspartate and three sodium ions, but insight in the kinetic mechanism of transport is fragmentary. …”
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    “…Background: It has been reported that thymidine kinase 1 (TK1) was up-regulated in multiple malignancies and participated in the regulation of tumor malignant behavior. …”
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  14. 54
    “…BACKGROUND AND PURPOSE: Bruton's TK (BTK) is a non‐receptor kinase best known for its role in B lymphocyte development that is critical for proliferation and survival of leukaemic cells in B‐cell malignancies. …”
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  15. 55
    “…TK1 is overexpressed in numerous cancers and is associated with to a poor prognosis. …”
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  16. 56
    “…Therefore, In order to reduce the GCV dose required, we aim to compare the therapeutic efficacy of HSV1-sr39TK, an HSV1-TK mutant with increased GCV prodrug catalytic activity, with wildtype TK in C6 glioma cells. …”
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  17. 57
    “…BACKGROUND: HSV-tk/ ganciclovir (GCV) gene therapy has been extensively studied in the setting of brain tumors and largely relies on the bystander effect. …”
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    “…However, the addition of the OMV-fraction collected from TK1402 could enhance biofilm formation. CONCLUSION: The results suggested that OMV produced from TK1402 play an important role in biofilm formation in strain TK1402.…”
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  20. 60
    “…The herpes simplex virus thymidine kinase (HSV-TK) is the most widely used suicide gene in cancer gene therapy due to its superior anticancer activity with ganciclovir compared to other HSV-TK substrates, such as 1-β-D-arabinofuranosyl thymine (araT). …”
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