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  1. 61
    por Dröge, J., Gregor, I., McHardy, A. C.
    Publicado 2015
    “…Results: Taxator-tk was precise in its taxonomic assignment across all ranks and taxa for a range of evolutionary distances and for short as well as for long sequences. …”
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    Taxator-tk: precise taxonomic assignment of metagenomes by fast approximation of evolutionary neighborhoods
  2. 62
    “…Despite its low transfer efficiency, suicide gene therapy with HSV-TK is known for its bystander killing effect. The connexin-based gap junction is believed to mediate the bystander effect. …”
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    Synergistic effect of resveratrol and HSV-TK/GCV therapy on murine hepatoma cells
  3. 63
    “…BACKGROUND: TK2 is a nuclear gene encoding the mitochondrial matrix protein thymidine kinase 2 (TK2), a critical enzyme in the mitochondrial nucleotide salvage pathway. …”
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    Bioavailability and cytosolic kinases modulate response to deoxynucleoside therapy in TK2 deficiency
  4. 64
    por Saada, Ann
    Publicado 2019
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    Insights into deoxyribonucleoside therapy for mitochondrial TK2 deficient mtDNA depletion
  5. 65
    “…The analyzes were conducted in vitro on human TK6 cells and mutagenicity were measured as micronucleus fold increase by flow cytometry. …”
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    Genotoxic Properties of Synthetic Cannabinoids on TK6 Human Cells by Flow Cytometry
  6. 66
    “…Then, we analyzed: mRNA levels and protein expression of MerTK and ADAM9, a protease that cleaves the extracellular region of MerTK; the amount of cleaved Mer (sMer); and the ability of GAS6, a MerTK ligand, to induce MerTK phosphorylation. …”
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    High Glucose Impairs Expression and Activation of MerTK in ARPE-19 Cells
  7. 67
    “…Despite the evidences of elevated expression of Mer tyrosine kinase (MerTK) in multiple human cancers, mechanisms underlying the oncogenic roles of MerTK in hepatocellular carcinoma (HCC) remains undefined. …”
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    N-glycosylation stabilizes MerTK and promotes hepatocellular carcinoma tumor growth
  8. 68
    “…BACKGROUND AND OBJECTIVE: TK2 deficiency (TK2d) is a rare mitochondrial disorder that manifests predominantly as a progressive myopathy with a broad spectrum of severity and age of onset. …”
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    Muscle MRI characteristic pattern for late-onset TK2 deficiency diagnosis
  9. 69
    “…SUMMARY: The Genome Taxonomy Database (GTDB) and associated taxonomic classification toolkit (GTDB-Tk) have been widely adopted by the microbiology community. …”
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    GTDB-Tk v2: memory friendly classification with the genome taxonomy database
  10. 70
    “…The aim was to determine if serum thymidine kinase 1 (sTK1) activity and sTK1 protein levels in dogs with mammary tumors could be useful in veterinary medicine. …”
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    Properties of cellular and serum forms of thymidine kinase 1 (TK1) in dogs with acute lymphocytic leukemia (ALL) and canine mammary tumors (CMTs): implications for TK1 as a proliferation biomarker
  11. 71
    “…In this collaborative study, a thymidine kinase gene mutation study (TK6 assay) using human lymphoblastoid TK6 cells, established in OECD TG490, was used to examine 10 chemicals that have conflicting results in mutagenicity studies (a positive Ames test and a negative result in rodent carcinogenicity studies). …”
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    Weight of evidence approach using a TK gene mutation assay with human TK6 cells for follow-up of positive results in Ames tests: a collaborative study by MMS/JEMS
  12. 72
    “…The signal transduction protein SmTK4 from Schistosoma mansoni belongs to the family of Syk kinases. …”
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    The Syk Kinase SmTK4 of Schistosoma mansoni Is Involved in the Regulation of Spermatogenesis and Oogenesis
  13. 73
    “…HSV-TK/GCV system in murine neuroblastoma induced systemic immunity. …”
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    Bystander-Mediated Regression of Murine Neuroblastoma via Retroviral Transfer of the HSV-TK Gene
  14. 74
    “…We conducted an in vitro study in TK6 cells to characterize gene expression signatures of exposure to 15 genotoxic carcinogens frequently used in European industries. …”
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    Effect of Chemical Mutagens and Carcinogens on Gene Expression Profiles in Human TK6 Cells
  15. 75
    “…L fruits was investigated for its antiproliferative and apoptotic activities on human lymphoblastoid TK6 cells. METHODS: We attempt to characterize the apoptotic pathway activated by DGA. …”
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    Investigation of the apoptotic way induced by digallic acid in human lymphoblastoid TK6 cells
  16. 76
    “…Here, we present the draft genome of Gordonia sp. strain UCD-TK1. The assembly contains 5,470,576 bp in 98 contigs. …”
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    Draft Genome Sequence of Gordonia sp. Strain UCD-TK1 (Phylum Actinobacteria)
  17. 77
    “…This study characterises the behaviour of (226)Ra and interfering elements on recently developed TK100 (Triskem International) extraction chromatography resin. …”
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    The behaviour of (226)Ra in high-volume environmental water samples on TK100 resin
  18. 78
    “…GFAP-TK mice are widely used in studies on neurogenesis and reactive astrocytes. …”
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    Enhanced Expression of Markers for Astrocytes in the Brain of a Line of GFAP-TK Transgenic Mice
  19. 79
    “…This abnormality involves decreased expression of MerTK and its ligands and can be rescued by treatment with TGFβ.…”
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    MerTK-mediated regulation of myelin phagocytosis by macrophages generated from patients with MS
  20. 80
    “…RESULTS: We demonstrate a significant expansion of resolution-like MerTK+HLA-DR(high) cells in circulatory and tissue compartments of patients with ALF. …”
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    MerTK expressing hepatic macrophages promote the resolution of inflammation in acute liver failure
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