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Mostrando 921 - 940 Resultados de 2,825 Para Buscar '"TK"', tiempo de consulta: 0.18s Limitar resultados
  1. 921
    “…CONCLUSIONS: The results of this study demonstrated that preoperative TK, preoperative LL, and Ponte osteotomy were related factors for maintaining normal TK. …”
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    A Retrospective Study of Factors Associated with Restoration of Thoracic Kyphosis in 43 Patients with Adolescent Idiopathic Scoliosis with Lenke Type 1 Curvature
  2. 922
    “…The association between LL and PI, LL and TK, was investigated to establish a predictive formula for ideal LL based on PI and TK. …”
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    Restoring Theoretically Optimal Lumbar Lordosis Deduced from Pelvic Incidence and Thoracic Kyphosis has Advantages to Decrease the Risk of Postoperative Mechanical Complications in Adult Spinal Deformity
  3. 923
    “…BACKGROUND: Thymidine kinase 2 (TK2) catalyses the phosphorylation of deoxythymidine (dThd) and deoxycytidine (dCtd) within mitochondria. …”
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    Age-related metabolic changes limit efficacy of deoxynucleoside-based therapy in thymidine kinase 2-deficient mice
  4. 924
    “…Patients were divided into two groups, according to their global thoracic kyphosis (TK): Group-A TK(T0) < 60°, Group-B TK(T0) ≥ 60°. …”
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    Maria Adelaide brace in the management of Scheuermann’s Kyphosis
  5. 925
    por Na, Il-Kang, le Coutre, Philipp
    Publicado 2015
    “…By now, medical oncologists and hematologists struggle to have a pool of potential TK inhibitors, where the most efficient one could be picked out to treat a specific cancer patient, which might also help overcome the occurring resistance mechanisms against TK inhibitors. …”
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    Emerging Role of Tyrosine Kinases as Drugable Targets in Cancer
  6. 926
    “…This suggests that a negative regulatory element is localized within the TK gene 5′‐UTR.…”
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    Optimizing fluorescent protein expression for quantitative fluorescence microscopy and spectroscopy using herpes simplex thymidine kinase promoter sequences
  7. 927
    “…In the design of TK-based DDS, different technological uses of TK have been proposed to overcome the major limitations of conventional DDS counterparts including uncontrolled drug release and off-target effects. …”
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    Applications of the ROS-Responsive Thioketal Linker for the Production of Smart Nanomedicines
  8. 928
    “…Among the orthopoxviruses variola virus induces in cells a characteristic thymidine kinase (TK) activity that can be feedback inhibited in reactions with thymidine triphosphate. …”
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    Nucleotide sequence of the thymidine kinase gene region of monkeypox and variola viruses
  9. 929
    “…The technology of tkLayout is presented, along with some results obtained in the context of the CMS Tracker design studies.…”
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    Software package for the characterization of Tracker layouts
  10. 930
    “…In this study, a recombinant strain named rPRV-XJ-ΔTK/gE/gI-VP2 was constructed by using the pseudorabies virus (PRV) variant strain XJ as the parental virus and by deleting the TK/gE/gI gene while coexpressing SVA VP2. …”
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    The Construction and Immunogenicity Analyses of a Recombinant Pseudorabies Virus with Senecavirus A VP2 Protein Coexpression
  11. 931
    “…Results of spatial transcriptome analysis showed that TK1 positive cells mainly localize in tumor area, and Treg cell infiltration in TNBC tissues was associated with high expression of TK1. …”
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    Regulatory T cells are associated with the tumor immune microenvironment and immunotherapy response in triple-negative breast cancer
  12. 932
    “…In this study, we constructed recombinant DNA plasmids (early growth response-1 tumor necrosis factor-α [pEgr1-TNFα], pEgr1 thymidine kinase [TK], and pEgr1-TNFα-TK) according to the Egr1 promoter sequence. …”
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    Efficacy and safety of dendrimer nanoparticles with coexpression of tumor necrosis factor-α and herpes simplex virus thymidine kinase in gene radiotherapy of the human uveal melanoma OCM-1 cell line
  13. 933
    “…The cell proliferation was measured by MTT assay, apoptosis was measured by probing cleaved Caspase3, EpCAM and TK expression were quantified by Western blot. Our results showed that the EGP2-promoter HSV-TK (EGP2-TK) construct with 2 or 4 copies of let-7b miRNA targets expressed TK gene only in Y79, WERI-Rb-1, while the TK gene did not express in MIO-M1. …”
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    Targeted Expression of Suicide Gene by Tissue-Specific Promoter and MicroRNA Regulation for Cancer Gene Therapy
  14. 934
    “…For each radiograph, several definitions of TK were measured as well as L1–S1 and nonfixed lumbar lordosis. …”
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    Reproducibility of thoracic kyphosis measurements in patients with adolescent idiopathic scoliosis
  15. 935
    “…In this study, we developed and evaluated a gene-deleted variant pseudorabies virus (PRV)-attenuated vaccine, PRV GX-ΔTK/IES, in which the genes TK, gI, gE, US9 and US2 were deleted. …”
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    Comprehensive evaluation of the safety and immunogenicity of a gene-deleted variant pseudorabies virus attenuated vaccine
  16. 936
    “…Objectives: Few studies have explored the use of spectral dual-layer detector-based computed tomography (SDCT) parameters, thymidine kinase-1 (TK1), and tumor abnormal protein (TAP) for the detection of ground-glass nodules (GGNs). …”
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    Spectral Dual-Layer Computed Tomography Can Predict the Invasiveness of Ground-Glass Nodules: A Diagnostic Model Combined with Thymidine Kinase-1
  17. 937
    “…The suspected sera samples (n = 30) were determined by TK-ELISA and the positive rate is 90% (27/30), and the TK-ELISA showed 83.33% (22+3/30) coincidence rate with the Serum Neutralization Test (SNT) and 90% (24+3/30) coincidence rate with the whole DPV virion based-ELISA (DPV-ELISA). …”
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    A Thymidine Kinase recombinant protein-based ELISA for detecting antibodies to Duck Plague Virus
  18. 938
    por Zhang, Shi-Yan, Lin, Bi-Ding, Li, Bu-Ren
    Publicado 2015
    “…The purpose of this study was to evaluate the diagnostic efficiency for hepatocellular carcinoma (HCC) with the combined analysis of alpha-l-fucosidase (AFU), alpha-fetoprotein (AFP) and thymidine kinase 1 (TK1). Serum levels of AFU, AFP and TK1 were measured in: 116 patients with HCC, 109 patients with benign hepatic diseases, and 104 normal subjects. …”
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    Evaluation of the diagnostic value of alpha-l-fucosidase, alpha-fetoprotein and thymidine kinase 1 with ROC and logistic regression for hepatocellular carcinoma
  19. 939
    “…BACKGROUND: Serum thymidine kinase type 1 (TK1) and canine C‐Reactive Protein (cCRP) might be useful in detecting dogs with cancer. …”
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    Thymidine Kinase Type 1 and C‐Reactive Protein Concentrations in Dogs with Spontaneously Occurring Cancer
  20. 940
    “…Most clinical ACVr HSV-1 isolates have mutations in the viral thymidine kinase (vTK) genes. The vTK-associated ACVr HSV-1 shows reduced virulence, but the association between the level of resistance and the virulence of the vTK-associated ACVr HSV-1 is still unclear. …”
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    Association between sensitivity of viral thymidine kinase-associated acyclovir-resistant herpes simplex virus type 1 and virulence
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