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  1. 981
    “…Selective cytotoxicity was observed in A549 but not non-lung cells that were transfected with pSPB-tk or infected with pSPB-tk–carrying JCPyV VLPs. …”
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    Gene Therapy for Human Lung Adenocarcinoma Using a Suicide Gene Driven by a Lung-Specific Promoter Delivered by JC Virus-Like Particles
  2. 982
    por Grobman, M., Outi, H., Rindt, H., Reinero, C.
    Publicado 2017
    “…HYPOTHESIS/OBJECTIVES: Compare serum concentrations of TK1, c‐CRP, HPT, and 25(OH)D in dogs with well‐ and poorly controlled primary IMHA, ITP, or IMPA. …”
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    Serum Thymidine Kinase 1, Canine‐C‐Reactive Protein, Haptoglobin, and Vitamin D Concentrations in Dogs with Immune‐Mediated Hemolytic Anemia, Thrombocytopenia, and Polyarthropathy
  3. 983
    “…This technique does not cause significant flattening of TK and results in a favorable restoration of TK in patients with hypokyphosis or hyperkyphosis.…”
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    Reciprocal Changes in Sagittal Alignment in Adolescent Idiopathic Scoliosis Patients Following Strategic Pedicle Screw Fixation
  4. 984
    “…RESULTS: Overall, the agreement between the DA and TK assays ranged from 20 to 93%. The isolates of A. baumannii showed variable results of synergism according to TK, and the calculated agreement was statistically significant in this species against fosfomycin with meropenem including colistin-resistant isolates. …”
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    Comparison of methods for the detection of in vitro synergy in multidrug-resistant gram-negative bacteria
  5. 985
    “…This study evaluated the accuracy of total keratometry (TK) and standard keratometry (K) for intraocular lens (IOL) power calculation in eyes treated with femtosecond laser-assisted cataract surgery. …”
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    Prediction accuracy of conventional and total keratometry for intraocular lens power calculation in femtosecond laser-assisted cataract surgery
  6. 986
    por Tribukait, Bernhard
    Publicado 2021
    “…Treatment resulted in a 2-fold increase of sTK1 before and a 3-fold increase 48 h after the cycles, except for the first cycle, where half of the patients reacted with a significant decrease and the other half with an increase of sTK1. …”
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    Dynamics of Serum Thymidine Kinase 1 at the First Cycle of Neoadjuvant Chemotherapy Predicts Outcome of Disease in Estrogen-Receptor-Positive Breast Cancer
  7. 987
    “…Transketolase (TK) has been previously engineered, using semi-rational directed evolution and substrate walking, to accept increasingly aliphatic, cyclic, and then aromatic substrates. …”
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    Biophysical characterization of the inactivation of E. coli transketolase by aqueous co-solvents
  8. 988
    “…The predicted PT and the TK of the uninstrumented thoracic spine correlated well with postoperative values (uninstrumented TK: R(2) = 0.764, P < .001; PT: R(2) = 0.868, P < .001). …”
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    Can Machine Learning Accurately Predict Postoperative Compensation for the Uninstrumented Thoracic Spine and Pelvis After Fusion From the Lower Thoracic Spine to the Sacrum?
  9. 989
    “…BACKGROUND: The thymidine kinase (tk) mutagenesis assay is often utilized to determine the frequency of herpes simplex virus (HSV) replication-mediated mutations. …”
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    Assessing the contribution of the herpes simplex virus DNA polymerase to spontaneous mutations
  10. 990
    “…BACKGROUND: One of the most frequently used and efficient suicide gene therapies for prostate cancer is HSV-TK/GCV system, but its application has been limited due to lack of favorable gene vector and the reduction of "bystander effect". …”
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    In vitro and in vivo double-enhanced suicide gene therapy mediated by generation 5 polyamidoamine dendrimers for PC-3 cell line
  11. 991
    “…We propose a model that explains how TK1 and dCK “tune” dCTP pools to both trigger and resolve RS in vivo. …”
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    Nucleoside salvage pathway kinases regulate hematopoiesis by linking nucleotide metabolism with replication stress
  12. 992
    “…Therefore, here we investigated the fate of a recombinant BoHV-4 strain expressing luciferase (BoHV-4-A-CMVlucΔTK) after intraperitoneal or intravenous inoculation in mice, by generating a novel recombinant BoHV-4 expressing luciferase (BoHV-4-A-CMVlucΔTK) and by following the virus replication through in vivo imaging analysis. …”
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    In Vivo Image Analysis of BoHV-4-Based Vector in Mice
  13. 993
    “…Compared with WT mice, VEGFR1 TK(-/-) mice exhibited delayed liver repair after hepatic I/R. …”
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    VEGFR1-Positive Macrophages Facilitate Liver Repair and Sinusoidal Reconstruction after Hepatic Ischemia/Reperfusion Injury
  14. 994
    “…TK VI increased auxin content and disrupted auxin response gradients in root tips. …”
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    Cellular and molecular insight into the inhibition of primary root growth of Arabidopsis induced by peptaibols, a class of linear peptide antibiotics mainly produced by Trichoderma spp.
  15. 995
    “…Inhibition of the B2R or ERK1/2 pathway abated the effects of TK, whereas an antagonist of B1R enhanced the effects. …”
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    Tissue Kallikrein Alleviates Cerebral Ischemia-Reperfusion Injury by Activating the B2R-ERK1/2-CREB-Bcl-2 Signaling Pathway in Diabetic Rats
  16. 996
    “…The translocation of HSV-TK provides significant resistance to AZT when compared to bacteria lacking a periplasmic HSV-TK. …”
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    A Positive Selection for Nucleoside Kinases in E. coli
  17. 997
    “…In the presence of bromide ion as template, TK(6+) formed exclusively at 50 °C in the same solvent. …”
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    [C–H···anion] interactions mediate the templation and anion binding properties of topologically non-trivial metal–organic structures in aqueous solutions
  18. 998
    “…Tai-Kadai (TK) is one of the major language families in Mainland Southeast Asia (MSEA), with a concentration in the area of Thailand and Laos. …”
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    New insights from Thailand into the maternal genetic history of Mainland Southeast Asia
  19. 999
    “…Only three chalcones (1c, 2a and 3e) had an inhibitory activity against EGFR-TK with a relative inhibition percentage that was close to the approved drug, erlotinib. …”
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    Biological Evaluation and Molecular Dynamics Simulation of Chalcone Derivatives as Epidermal Growth Factor-Tyrosine Kinase Inhibitors
  20. 1000
    “…OBJECTIVES: The TK behavior of BPA and BPS was investigated by administering the two compounds by intravenous and oral routes in piglet, a known valid model for investigating oral TK. …”
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    Oral Systemic Bioavailability of Bisphenol A and Bisphenol S in Pigs
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