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  1. 1101
    “…An adverse effect of HSV‐TK/GCV gene therapy was acute hepatotoxicity, which was not found after Ad.CAG lacZ gene transfer, but was found after high‐titer Ad.CAGHSV‐TK gene transfer followed by GCV. …”
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    In situ Gene Transfer and Suicide Gene Therapy of Gastric Cancer Induced by N‐Ethyl‐N′‐nitro‐N‐nitrosoguanidine in Dogs
  2. 1102
    “…The results of PI, PT, SS, LL, TK, CL, SVA, PR-T12, SSA and SPA values suggested that age was positively correlated with TK, CL and SVA, while it was negatively correlated with LL, PR-T12 and SSA. …”
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    Characteristics of sagittal spinopelvic alignment in asymptomatic Han Chinese adults
  3. 1103
    “…In this study, we constructed a semi-and pseudotyped-RRV (sp-RRV) system harboring two suicide genes—herpes simplex virus type 1 thymidine kinase (TK) and yeast cytosine deaminase (CD)—to verify the dissemination and antitumor efficacy of our sp-RRV system (spRRVe-sEF1α-TK/sRRVgp-sEF1α-CD) in seven patient-derived glioblastoma stem-like cells (GSCs). …”
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    Novel Semi-Replicative Retroviral Vector Mediated Double Suicide Gene Transfer Enhances Antitumor Effects in Patient-Derived Glioblastoma Models
  4. 1104
    “…Therefore, to investigate the role of these adult-born neurons more precisely, we used nestin-HSV-TK transgenic mice (Nes-TK) to selectively ablate newborn neurons. …”
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    Genetic Ablation of Neural Progenitor Cells Impairs Acquisition of Trace Eyeblink Conditioning
  5. 1105
    “…TkTV1 purified isometric virions were ∼38–40 nm in diameter and were able to transfect T. koningiopsis and C. rosea protoplasts. …”
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    A Novel Totivirus Naturally Occurring in Two Different Fungal Genera
  6. 1106
    “…Co-infections of these diseases often occur in the field, posing significant threat to the swine industry worldwide. gE/gI/TK-gene-deleted vaccines are safe and capable of providing full protection against PR. …”
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    Generation and Immunogenicity of a Recombinant Pseudorabies Virus Co-Expressing Classical Swine Fever Virus E2 Protein and Porcine Circovirus Type 2 Capsid Protein Based on Fosmid Library Platform
  7. 1107
    “…CONCLUSIONS: In the natural sitting position, a reduction in LL was associated with TK, SVA and PT increased, and there were differences between men and women. …”
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    Sagittal Spinal and Pelvic Alignment in Middle-Aged and Older Men and Women in the Natural and Erect Sitting Positions: A Prospective Study in a Chinese Population
  8. 1108
    “…The novel compound shows the same activity against thymidine kinase (TK)-competent (TK(+)) and TK-deficient (TK(−)) VZV strains, pointing to a novel mechanism of antiviral action.…”
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    Identification of an indol-based derivative as potent and selective varicella zoster virus (VZV) inhibitor
  9. 1109
    “…TK mice treated with VGCV were unable to recognize conspecifics as familiar 24 h after initial exposure. …”
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    Adult-Born Neurons in the Hippocampus Are Essential for Social Memory Maintenance
  10. 1110
    “…PURPOSE: Galectin-3 (gal-3) is a soluble glycoprotein that has been associated with diverse forms of phagocytosis, including some mediated by the engulfment receptor MerTK. Retinal pigment epithelium (RPE) in vivo uses MerTK (or the related Tyro3) for phagocytosis of shed outer segment fragments during diurnal outer segment renewal. …”
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    Diurnal Photoreceptor Outer Segment Renewal in Mice Is Independent of Galectin-3
  11. 1111
    “…The effect of Last T1S was significantly associated with the Last CL; the effect of Last TK, with the Last T1S; and the effect of Post PI-LL, with the Last TK (p < .05). …”
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    Transiency of postoperative cervical kyphosis seen after surgical correction of sagittal malalignment in adult spinal deformity patients
  12. 1112
    “…In the present work, we used the bovine herpesvirus-4-based vector (BoHV-4-A) to deliver PPRV hemagglutinin H antigen (BoHV-4-A-PPRV-H-ΔTK). Vaccination with BoHV-4-A-PPRV-H-ΔTK protected sheep from virulent PPRV challenge and prevented virus shedding. …”
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    Immunization With Bovine Herpesvirus-4-Based Vector Delivering PPRV-H Protein Protects Sheep From PPRV Challenge
  13. 1113
    “…The Herpes Simplex Virus Thymidine Kinase (HSV-TK) and ganciclovir (GCV) system has been extensively studied in the context of SCI and broader CNS disease. …”
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    Neural Progenitor Cells Expressing Herpes Simplex Virus-Thymidine Kinase for Ablation Have Differential Chemosensitivity to Brivudine and Ganciclovir
  14. 1114
    “…Therefore, this study aims to investigate short-, medium-, and long-term health effects of a web-based health program (“TK-HealthCoach”, TK-HC) offered by a national statutory health insurance fund (Techniker Krankenkasse, TK). …”
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    Health Effects of a 12-Week Web-Based Lifestyle Intervention for Physically Inactive and Overweight or Obese Adults: Study Protocol of Two Randomized Controlled Clinical Trials
  15. 1115
    “…RESULTS: Fifteen patients (29 eyes) with TK and atypical corneal involvement due to amyloid deposition were identified. …”
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    Atypical Corneal Phenotype in Patients With Trachoma and Secondary Amyloidosis
  16. 1116
    “…The results showed that the amino acid sequence homology of the gD, gL, and TK proteins of hSD-1 2019 and JL-CC was 97.5%, 94.4%, and 99.1%, respectively. …”
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    Mutation and Interaction Analysis of the Glycoprotein D and L and Thymidine Kinase of Pseudorabies Virus
  17. 1117
    “…As a result, we have been able to produce Tk-hefu-11 that shows an EC(50) of ≈70 nM against K(V)1.3. …”
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    Artificial pore blocker acts specifically on voltage-gated potassium channel isoform K(V)1.6
  18. 1118
    “…Further, the absence of Learning Management Systems (LMS) forced some to use social media platforms to conduct remote teaching, impacting their TK, impacting their TK. Given the low TK levels, it is suggested that higher education institutions increase the use of online learning platforms (e.g., LMS) and technologies (e.g., augmented reality and virtual reality technologies, which will be highly useful especially for practice-based courses). …”
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    Effects of socio-demographic and technological factors on Indonesian lecturers’ TPACK: insights from emergency remote learning
  19. 1119
    “…BACKGROUND: The Thymidine kinase (Tk) mutants generated from the widely used L5178Y mouse lymphoma assay fall into two categories, small colony and large colony. …”
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    Microarray analysis distinguishes differential gene expression patterns from large and small colony Thymidine kinase mutants of L5178Y mouse lymphoma cells
  20. 1120
    “…Life-stage-dependent toxicity and dose-dependent toxicokinetics (TK) were evaluated in Sprague Dawley rats following dietary exposure to 2,4-dichlorophenoxyacetic acid (2,4-D). 2,4-D renal clearance is impacted by dose-dependent saturation of the renal organic anion transporter; thus, this study focused on identifying inflection points of onset of dietary nonlinear TK to inform dose selection decisions for toxicity studies. …”
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    Life-Stage-, Sex-, and Dose-Dependent Dietary Toxicokinetics and Relationship to Toxicity of 2,4-Dichlorophenoxyacetic Acid (2,4-D) in Rats: Implications for Toxicity Test Dose Selection, Design, and Interpretation
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