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  1. 1261
    “…TK5048 and its derivatives, AM‐132, AM‐138, and AM‐97, are recently developed antimitotic (AM) compounds. …”
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    Enhancement of in vivo Antitumor Activity of a Novel Antimitotic 1‐Phenylpropenone Derivative, AM‐132, by Tumor Necrosis Factor‐cc or Interleukin‐6
  2. 1262
    “…We show that a fast proliferating variety of hAMSCs expressing thymidine kinase (TK) has therapeutic capacity equivalent to that of TK-expressing hAMSCs and can be used in a multiple-inoculation procedure to reduce GB tumors to a chronically inhibited state. …”
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    Glioblastoma Bystander Cell Therapy: Improvements in Treatment and Insights into the Therapy Mechanisms
  3. 1263
    “…Different taxa that were core-enriched from the dominant taxa in the bulk soil, rhizosphere soil, and root endosphere displayed varied time–decay relationships. Soil total potassium (TK) as a key factor regulated the temporal variation in some individual taxa in the bulk and rhizosphere soils; these taxa were associated with the adjustment of root secondary metabolites across different TK levels. …”
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    Soil potassium is correlated with root secondary metabolites and root-associated core bacteria in licorice of different ages
  4. 1264
    por Li, Wei, Zlatanova, Sisi
    Publicado 2021
    “…Furthermore, we extend a significant GSG detection problem to top-k geo-social group (TkGSG) mining. Rather than extracting all qualified GSGs in a network, TkGSG aims to return k feasibility groups to guarantee the diversity. …”
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    Significant Geo-Social Group Discovery over Location-Based Social Network †
  5. 1265
    “…RESULTS: Our results show that GFAP‐Tk male rats present a heightened acute stress response. …”
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    Suppression of adult cytogenesis in the rat brain leads to sex‐differentiated disruption of the HPA axis activity
  6. 1266
    “…Outputs from a physiologically based toxicokinetic (PB-TK) model for fish were visualized by mapping time-series data for specific tissues onto a three-dimensional representation of a rainbow trout. …”
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    Three-dimensional visualization of physiologically based kinetic model outputs.
  7. 1267
    por Belk, A T
    Publicado 1991
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    K0 production and data acquisition with aleph
  8. 1268
    “…METHODS: We analyzed node ages in Isoetes using two genomic data sets (plastome and nuclear ribosomal cistron), three clock models implemented in MrBayes (ILN, WN, and TK02 models), and a conservative approach to calibration. …”
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    No phylogenomic support for a Cenozoic origin of the “living fossil” Isoetes
  9. 1269
    “…Calcium imaging analysis revealed that mechanical threats are encoded in Tk-GAL4(2) ∩ Vglut neurons as elevated activity. …”
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    Threat gates visual aversion via theta activity in Tachykinergic neurons
  10. 1270
    “…Kyphosis of the five apical vertebrae and TK were significantly greater in the surgery with the outrigger (p = 0.002). …”
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    Rod Rotation with Outrigger Is Substantial for Correcting Apical Hypokyphosis in Patients with Adolescent Idiopathic Scoliosis: Novel Outrigger Device for Concave Rod Rotation
  11. 1271
    “…The cytotoxicity and the antivirus activity of Pd(II) and Pt(II) complexes with pyridine-2-carbaldehyde thiosemicarbazone (HFoTsc) against HSV replication were evaluated on four HSV strains—two wt strains Victoria (HSV-1) and BJA (HSV-2) and two ACV(R) mutants with different tk gene mutations R-100 (TK(A), HSV-1) and PU (TK(N), HSV-2). …”
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    Platinum(II) and Palladium(II) Complexes of Pyridine-2-Carbaldehyde Thiosemicarbazone as Alternative Antiherpes Simplex Virus Agents
  12. 1272
    “…Fibroatheromas were grouped into early fibroatheroma, late fibroatheroma, thick-cap fibroatheroma (TkCFA), and thin-cap fibroatheroma. RESULTS: Mean patient age was 45±11 years old and 71% were males. …”
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    Progression and Observational Frequency of Atheromatous Plaques in Autopsied Coronary Arteries
  13. 1273
    “…Our study herein demonstrates the generation of the triple mosaic Ad vector with pK, HSV-1 TK, and mRFP1 at the carboxyl termini of Ad minor capsid protein IX (pIX). …”
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    Derivation of a Triple Mosaic Adenovirus for Cancer Gene Therapy
  14. 1274
    por Fisher, Robin, Xie, Yuan-Yun
    Publicado 2010
    “…The volume, area and thickness of the pallium were measured in an E12–P4 (postnatal age 4) longitudinal study with comparisons between ablated (HSV-TK(+/0)) and control (HSV-TK(0/0)) littermates. …”
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    Growth defects in the dorsal pallium after genetically targeted ablation of principal preplate neurons and neuroblasts: a morphometric analysis
  15. 1275
    “…The aim of this study is to find out whether HBx protein expression affects antiproliferative effect of an epidermal growth factor receptor-tyrosine kinase (EGFR-TK) inhibitor and a MEK inhibitor in HepG2 and Huh-7 cell lines. …”
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    Could HBx Protein Expression Affect Signal Pathway Inhibition by Gefitinib or Selumetinib, a MEK Inhibitor, in Hepatocellular Carcinoma Cell Lines?
  16. 1276
    “…Using in vivo syngeneic esophageal carcinoma models, combining surgery, chemotherapy and AdV-tk/GCV improved survival (P=0.007) and decreased disease recurrence (P<0.001). …”
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    Neoadjuvant in situ gene-mediated cytotoxic immunotherapy improves postoperative outcomes in novel syngeneic esophageal carcinoma models
  17. 1277
    “…HSV-TK gene expression was controlled by the adenoviral E4 promoter, which is activated in the presence of the adenoviral E1 gene products (i.e., when adenovirus is present in the cell). …”
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    Combinatorial targeting of 2 different steps in adenoviral DNA replication by herpes simplex virus thymidine kinase and artificial microRNA expression for the inhibition of virus multiplication in the presence of ganciclovir
  18. 1278
    “…Förster resonance energy transfer between fluorophores attached to the IR tyrosine kinase (TK) domain showed that a change in the TK domain occurred upon prolonged, but not short-term, insulin exposure. …”
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    Insulin Resistance Induced by Hyperinsulinemia Coincides with a Persistent Alteration at the Insulin Receptor Tyrosine Kinase Domain
  19. 1279
    “…Micafungin (2 μg/ml) was fungicidal (≥ 3 log(10) reduction) in TK against 5 out of 14 (36%) strains of C. albicans complex. …”
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    Postantifungal Effect of Micafungin against the Species Complexes of Candida albicans and Candida parapsilosis
  20. 1280
    “…No expression of the first ten amino acids of the MerTK mutant fused with the DsRed2 fluorescent protein was detected in HEK293T cells, indicating that the mutation affects the translation initiation site of the gene that may lead to loss of function of the MerTK signaling pathway. …”
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    A novel start codon mutation of the MERTK gene in a patient with retinitis pigmentosa
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