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  1. 1521
    “…Enhanced green fluorescent protein (eGFP) DNA and the mini-F sequences were inserted into the gene encoding HVT thymidine kinase (TK) by homologous recombination in chicken embryo fibroblasts (CEFs), and the constructed HVT-BAC vector was used to transform Escherichia coli (pHVT-BAC). …”
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    Removal of Inserted BAC after linearizatiON (RIBON)—a novel strategy to excise the mini-F sequences from viral BAC vectors
  2. 1522
    “…In this study, we examined the effects of a new selective MMP inhibitor, MMI‐166, on tumor growth, angiogenesis and metastasis in a liver meta‐static model of human xenotransplanted colon cancer (TK‐4). We also investigated the synergistic effects of MMI‐166 and a conventional cytotoxic agent, mitomycin C (MMC), in this model. …”
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    Effect of Combination Therapy with Matrix Metalloproteinase Inhibitor MMI‐166 and Mitomycin C on the Growth and Liver Metastasis of Human Colon Cancer
  3. 1523
    “…This TK-deleted virus, deVV5-fcu1 replicated efficiently in human tumor cells, and was notably attenuated in normal primary cells. …”
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    Vaccinia Virus Shuffling: deVV5, a Novel Chimeric Poxvirus with Improved Oncolytic Potency
  4. 1524
    por Nakamura, Toshitsugu
    Publicado 2018
    “…SCD can be differentiated from epidermal keratinization (EK) and trichilemmal keratinization (TK) based on the expression pattern of beta-catenin, ssDNA, and caspase-14/CD138. …”
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    Shadow Cell Differentiation: A Comparative Analysis of Modes of Cell Death with Apoptosis and Epidermal/Trichilemmal Keratinization
  5. 1525
    “…Thirty-six canine mammary carcinoma patients received injections of canine interferon-β (cIFN-β) and HSV-thymidine kinase/ganciclovir (HSV-tk/GCV) carrying lipoplexes, into the tumor bed, immediately after surgery. …”
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    Combination of Suicide and Cytokine Gene Therapies as Surgery Adjuvant for Canine Mammary Carcinoma
  6. 1526
    “…This TK-deleted Raccoonpox virus was notably attenuated in normal primary cells but replicated efficiently in numerous tumor cell lines. …”
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    Oncolytic properties of non-vaccinia poxviruses
  7. 1527
    “…Tyrosine kinase (TK), vascular endothelial growth factor (VEGF), and matrix metalloproteinases (MMP) are important cancer therapeutic target proteins. …”
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    Potential Anti-Cancer Flavonoids Isolated From Caesalpinia bonduc Young Twigs and Leaves: Molecular Docking and In Silico Studies
  8. 1528
    “…These findings provide new insight into PCa pathogenesis, and identify LMNB1, TK1, RACGAP1 and ZWINT as candidate biomarkers for diagnosis and prognosis of PCa.…”
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    Identification of hub genes in prostate cancer using robust rank aggregation and weighted gene co-expression network analysis
  9. 1529
    “…The lycopene produced by TK-3 was quantified as 0.49 ​g/kg CDW (cell dry weight).…”
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    Engineering the carotenoid biosynthetic pathway in Rhodothermus marinus for lycopene production
  10. 1530
    “…Here, we studied the oncolytic activity of VV thymidine kinase (TK)-ribonucleotide reductase (RR)-/green fluorescent protein (GFP) against MPM. …”
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    High Oncolytic Activity of a Double-Deleted Vaccinia Virus Copenhagen Strain against Malignant Pleural Mesothelioma
  11. 1531
    “…Limited studies are available on EGFR-TK mutations in the head and neck squamous cell carcinoma (HNSCC) globally. …”
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    Study of EGFR mutations in head and neck squamous cell carcinomas
  12. 1532
    “…All target compounds performed significantly inhibitory effects against wild type epidermal growth factor receptor tyrosine kinase (EGFR(wt)-TK) and tumour cells (A431, A549, MCF-7, and NCI-H1975). …”
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    Synthesis and preliminary structure-activity relationship study of 3-methylquinazolinone derivatives as EGFR inhibitors with enhanced antiproliferative activities against tumour cells
  13. 1533
    “…Pearson correlation analysis showed that soil pH, SOC, TN, TP, and TK were the main environmental factors that affected the diversity and richness of soil bacterial communities. …”
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    Effects of organic materials on soil bacterial community structure in long-term continuous cropping of tomato in greenhouse
  14. 1534
    “…The fluorophilic effect mediated efficient cellular uptake and endosomal escape while ROS-responsive TK linker allowed the polyplex disassembly to decrease the cytotoxicity of the polycations and improve the release of payloads at specific sites. …”
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    ROS responsive polyethylenimine-based fluorinated polymers for enhanced transfection efficiency and lower cytotoxicity
  15. 1535
    “…Results indicated that pH, EC, total phosphorus (TP) and total potassium (TK) were increased and total organic carbon (TOC) and total nitrogen (TN) were decreased during the composting of industrial sludge with biochar compared with the control (sludge without biochar). …”
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    Application of Rice Husk Biochar and Earthworm on Concentration and Speciation of Heavy Metals in Industrial Sludge Treatment
  16. 1536
    por Ñamendys-Silva, Silvio A.
    Publicado 2020
    “…Healthcare workers can be infected in the community, and in interactions with colleagues; therefore, such infections are not always the result of acquisition from infected patients https://bit.ly/30opbTk…”
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    Healthcare workers with COVID-19 in Mexico
  17. 1537
    por Pardo Carpio, Fernando
    Publicado 2000
    Libro
    VHDL : Lenguaje para síntesis y modelado de circuitos /
  18. 1538
    por Bijnens, J, Meißner, Ulf G
    Publicado 1996
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    Workshop on the Standard Model at Low Energies
  19. 1539
    “…Radiographic parameters showed that SVA, PT, and PI-LL mismatch were significantly decreased, while C2C7 Cobb, TK, SS, and LL were significantly increased after the intervention. …”
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    A Change in Global Sagittal Alignment after Transforaminal Epidural Steroid Injections in Lumbar Spinal Stenosis
  20. 1540
    “…Posterior-only approach is safe and effective method for correction of the TK and improving the signs and symptoms of the patients.…”
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    Atypical Scheuermann's disease with severe kyphosis and negative sagittal balance in the thoracolumbar region: A case report and literature review
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