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1861“…Protein kinases are presented according to their group in the human kinome: TK (Trk, RET, EGFR, JAK, VEGFR, SFK, BCR–Abl), CMGC (p38 MAPK, MEK, ERK, JNK, ASK1, CDK, CLK2, DYRK1A, GSK3, CK2), AGC (PKA, PKB, PKC, PKMζ, PKG, ROCK), CAMK, CK1 and atypical/other protein kinases (IKK, mTOR). …”
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1862“…The video can be found here: https://youtu.be/TK-WybKnGJM…”
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1863por Del Burgo, Riccardo“…A simulation software called tkLayout has been used to estimate the performance of different detector layouts. …”
Publicado 2022
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1864por Yang, Canchun, Zeng, Ziliang, Yan, Haolin, Wu, Jionglin, Lv, Xin, Zhang, Di, Zhang, Zhilei, Jiang, Xu, Zhang, Chi, Fu, Guo, Peng, Xiaoshuai, Wang, Zheyu, Zhao, Qiancheng, Li, Wenpeng, Huang, Renyuan, Wang, Qiwei, Li, Bo, Hu, Xumin, Wang, Peng, Gao, Liangbin“…RESULTS: The VBCO could provide comparable restoring of CBVA, GK, TK, and LL in the eggshell osteotomy procedure (all p > 0.05). …”
Publicado 2023
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1865por Gedikbasi, Asuman, Toksoy, Guven, Karaca, Meryem, Gulec, Cagri, Balci, Mehmet Cihan, Gunes, Dilek, Gunes, Seda, Aslanger, Ayca Dilruba, Unverengil, Gokcen, Karaman, Birsen, Basaran, Seher, Demirkol, Mubeccel, Gokcay, Gulden Fatma, Uyguner, Zehra Oya“…Also, it contributes to making treatment-helpful referrals, such as ensuring early access to medication for patients with mutations in the TK2 gene.…”
Publicado 2023
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1866“…Univariate analysis showed a significant correlation between ΔTK, ΔLL, ΔCVA and the amount of mid-term improvement in quality of life, but multivariate analysis did not get a significant result. …”
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1867por Matsumoto, Tomiya, Okuda, Shinya, Nagamoto, Yukitaka, Takahashi, Yoshifumi, Furuya, Masayuki, Iwasaki, Motoki“…Correlations of ΔSL and changes in other spinopelvic parameters (ΔSVA, ΔTPA, ΔTK, ΔLL, ΔSS, ΔPT, and ΔPI-LL) between preoperatively and 3 months postoperatively were examined. …”
Publicado 2023
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1868por Saban, Ricardo, Simpson, Cindy, Vadigepalli, Rajanikanth, Memet, Sylvie, Dozmorov, Igor, Saban, Marcia R“…BACKGROUND: Tachykinins (TK), such as substance P, and their neurokinin receptors which are ubiquitously expressed in the human urinary tract, represent an endogenous system regulating bladder inflammatory, immune responses, and visceral hypersensitivity. …”
Publicado 2007
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1869por Okada, Hideho, Lieberman, Frank S, Walter, Kevin A, Lunsford, L Dade, Kondziolka, Douglas S, Bejjani, Ghassan K, Hamilton, Ronald L, Torres-Trejo, Alejandro, Kalinski, Pawel, Cai, Quan, Mabold, Jennifer L, Edington, Howard D, Butterfield, Lisa H, Whiteside, Theresa L, Potter, Douglas M, Schold, S Clifford, Pollack, Ian F“…In UPCI 99-111, adult participants with newly diagnosed GBM or AA, following GTR and radiation therapy, received two intradermal vaccinations with the TFG-IL4-Neo-TK-transfected fibroblasts admixed with type-1 dendritic cells (DC) loaded with autologous tumor lysate. …”
Publicado 2007
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1870Cell cycle-dependent activity of the novel dual PI3K-MTORC1/2 inhibitor NVP-BGT226 in acute leukemiapor Kampa-Schittenhelm, Kerstin Maria, Heinrich, Michael Charles, Akmut, Figen, Rasp, Katharina Henriette, Illing, Barbara, Döhner, Hartmut, Döhner, Konstanze, Schittenhelm, Marcus Matthias“…In some cases, constitutive AKT activation can be linked to gain-of-function tyrosine kinase (TK) mutations upstream of the PI3K/AKT pathway. …”
Publicado 2013
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1871por Yang, Changwei, Yang, Mingyuan, Chen, Yuanyuan, Wei, Xianzhao, Ni, Haijian, Chen, Ziqiang, Li, Jingfeng, Bai, Yushu, Zhu, Xiaodong, Li, Ming“…With regard to the sagittal balance, there were significant differences in age, LL, PT, coronal Cobb angle, degree of apical vertebra rotation, and PI − LL between imbalanced group and balanced group (all P < 0.05); however, no significant difference was observed in gender, TK, TL, SS, and PI. Our study provided the general radiographic parameters of ADS. …”
Publicado 2015
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1872por Miossec, Matthieu J., Valenzuela, Sandro L., Pérez-Losada, Marcos, Johnson, W. Evan, Crandall, Keith A., Castro-Nallar, Eduardo“…METHODS: We assessed eight popular taxonomic profiling pipelines; MetaPhlAn2, metaMix, PathoScope 2.0, Sigma, Kraken, ConStrains, Centrifuge and Taxator-tk, against a battery of metagenomic datasets simulated from real data. …”
Publicado 2020
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1873por Lin, Guanfeng, Wang, Shengru, Yang, Yang, Su, Zhe, Du, You, Xu, Xiaolin, Chai, Xiran, Wang, Yipeng, Yu, Bin, Zhang, Jianguo“…RESULTS: GK improved from a median of 74.1° to 40.0° after surgery, achieving a correction rate of 48.8% with a median correction loss of 0.8°. TK, TL and LL all showed significant difference (P < 0.05) and SVA improved 22.7 (11.6, 30.9) mm post operation. …”
Publicado 2021
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1874por Song, Di‐yu, Zhang, Zi‐fang, Wang, Tian‐hao, Qi, Deng‐bin, Wang, Yan, Zheng, Guo‐quan“…Pre‐operativethoracic kyphosis (TK), thoracolumbar kyphosis (TLK), lumbar lordosis (LL), and sagittal vertical axis (SVA) were 52.4°, 49.1°, 42.7°, and 315 mm, respectively. …”
Publicado 2021
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1875“…The radiological parameters for measuring the sagittal alignment were included: C7-sagittal vertical axis (SVA), T1 pelvic angle (TPA), lumbar lordosis (LL), thoracic kyphosis (TK), pelvic tilt (PT), sacral slope (SS), pelvic incidence (PI). …”
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1876“…There was no significant difference in PI, PT, SS, LL, TK, LSJA, and SVA between the two groups before and 6 months after operation (P > 0.05). …”
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1877“…There was no significant difference in TK, LL and SVA before and after revision surgery (all P > 0.05). …”
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1878por Gmyrek, Grzegorz B., Berube, Amanda N., Sjoelund, Virginie H., Carr, Daniel J. J.“…Collectively, the results suggest (1) the live-attenuated HSV-1 mutant 0∆NLS elicits a robust B cell response that drives select B cell responses greater than the parental HSV-1 and (2) HSV-1 TK and gM are likely expendable components in efficacy of a humoral response to ocular HSV-1 infection.…”
Publicado 2022
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1879por Baek, Suji, Kwon, Seung Hae, Jeon, Joo Yeong, Lee, Gong Yeal, Ju, Hyun Soo, Yun, Hyo Jung, Cho, Dae Jin, Lee, Kang Pa, Nam, Myung Hee“…BACKGROUND: Tyrosine kinase (TK) plays a crucial role in the pathogenesis of idiopathic pulmonary fibrosis. …”
Publicado 2022
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1880por Chen, Kangming, Wu, Jinyan, Huang, Gangyong, Liu, Changquan, Shen, Chao, Zhu, Junfeng, Li, Yang, Li, Tao, Xiao, Fei, Peng, Jianping, Han, Xiuguo, Zhang, Xinhai, Xia, Jun, Chen, Xiaodong“…RESULTS: PT, SS, LL and TK differed significantly between standing and sitting within each group except for TK in degenerative group (32.8 ± 13.9 vs. 32.9 ± 14.2, p = 0.905). …”
Publicado 2022
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