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  1. 1941
    “…Moreover, SLFN11 expression was inhibited by the ETS inhibitor TK216. Our study reveals that SLFN11 expression is regulated via the JAK, AKT and ERK, and ETS axis. …”
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    Schlafen 11 expression in human acute leukemia cells with gain-of-function mutations in the interferon-JAK signaling pathway
  2. 1942
    por Wei, Yifeng, Tong, Yang, Zhang, Yan
    Publicado 2022
    “…Studies in recent years have uncovered an unexpectedly diverse array of sulfoglycolytic pathways in different bacteria, including one analogous to the Embden–Meyerhof–Parnas pathway (sulfo-EMP), one analogous to the Entner–Doudoroff pathway (sulfo-ED), and two involving sulfo-sugar cleavage by a transaldolase (sulfo-TAL) and transketolase (sulfo-TK), respectively, analogous to reactions in the pentose phosphate (PP) pathway. …”
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    New mechanisms for bacterial degradation of sulfoquinovose
  3. 1943
    “…RESULTS: A population of F(2:9) recombinant inbred lines (RILs) was derived from the cross between an elite japonica Taiwanese cultivar ‘Taikeng 16 (TK16)’ and an indica variety ‘Budda’. ‘Budda’ was found highly resistant to all 24 representative isolates of the F. fujikuroi population in Taiwan. …”
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    Identification of qBK2.1, a novel QTL controlling rice resistance against Fusarium fujikuroi
  4. 1944
    “…Plasma deoxyuridine (dUrd) levels and thymidine kinase 1 (TK1) activity were measured before each scan. Patients were then treated with the combination therapy. …”
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    A Subset of Non-Small Cell Lung Cancer Patients Treated with Pemetrexed Show (18)F-Fluorothymidine “Flare” on Positron Emission Tomography
  5. 1945
    “…Perioperatively, all spinopelvic parameters regarding to TK, LL, SS, PT, TPA, SVA, and mismatch (PI‐LL) had significant changes (P < 0.001). …”
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    Association of Sagittal Spinopelvic Realignment with Correction in Lower Lumbar Lordosis after Surgical Treatment in Degenerative Lumbar Scoliosis
  6. 1946
    “…In the sagittal plane, PSF patients had significantly larger lumbar lordosis (LL, 59.1° ± 10.5°), thoracic kyphosis (TK, 37.2° ± 13.3°) and proximal junctional angle (PJA, 13.3° ± 6.1°) at the last follow‐up than the ASF (LL: 43.4° ± 9.4°; TK: 20.7° ± 8.4°; PJA: 4.7° ± 3.4°; P < 0.05), but without significant difference in proximal junctional kyphosis (PJK) and sagittal vertical axis (SVA) (P > 0.05). …”
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    Anterior Selective Lumbar Fusion Saving More Distal Fusion Segments Compared with Posterior Approach in the Treatment of Adolescent Idiopathic Scoliosis with Lenke Type 5: A Cohort Study with More Than 8‐Year Follow‐up
  7. 1947
    “…After bracing, TK and LL decreased slightly (from 29° ± 6° and 42° ± 8° to 23° ± 3° and 38° ± 6°; p < 0.001), whereas the thoracolumbar junction (TLJ) value increased (from 3° ± 3° to 11° ± 3°; p < 0.001). …”
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    Do the three-dimensional parameters of brace-wearing patients with AIS change when transitioning from standing to sitting position? A preliminary study on Lenke I
  8. 1948
    “…Compared with the preoperative values, the C(7)T, GK, TK, TLK, LK, AFL, PT, SS and SVA values of all patients were significantly improved at the last follow-up (P < 0.05); GK improved from 81.62 ± 16.11 to 50.15 ± 8.55, with an average of 31° of correction (F = 75.945, P<0.001). …”
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    Treatment of ankylosing spondylitis complicated with a thoracolumbar Andersson lesion by posterior closed osteotomy, debridement and fusion through the fracture line
  9. 1949
    “…Upon dual inputs of tumor-associated GSH and TK1 mRNA, DNA logic circuits perform “AND” logic computation and initiate the toehold-mediated strand displacement reaction. …”
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    Smart down/upconversion nanomachines integrated with “AND” logic computation and enzyme-free amplification for NIR-II fluorescence-assisted precise and enhanced photodynamic therapy
  10. 1950
    “…EMF fungi and soil bacteria were correlated with edaphic factors, especially the soil pH, TP, and TK, caused by stand development. The results show that the community characteristics of ECM fungi and bacteria in the typical tree species of the Junzifeng National Nature Reserve reflect the critical role of soil microorganisms in stabilizing forest ecosystems.…”
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    The Ectomycorrhizal Fungi and Soil Bacterial Communities of the Five Typical Tree Species in the Junzifeng National Nature Reserve, Southeast China
  11. 1951
    “…DHC exposure in the human TK6 lymphoblastoid cell line also caused concentration-dependent increases in p53 acetylation and cytotoxicity. …”
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    The Flavoring Agent Dihydrocoumarin Reverses Epigenetic Silencing and Inhibits Sirtuin Deacetylases
  12. 1952
    por Sahin, Fikret, Sladek, Todd L.
    Publicado 2010
    “…For example, E2F-1 acts as part of the repression complex with pRB in the expression of DHFR, b-myb, TK and cdc2 in asynchronously growing cells; on the other hand, E2F-1 acts as an activator in the expression of the same genes in cells that are re-entering the cycle.…”
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    E2F-1 has dual roles depending on the cell cycle
  13. 1953
    “…Bioinformatic analyses revealed a number of putative TH responsive elements (TRE) located in the critical regulatory regions of HSV-1 genes such as thymidine kinase (TK), latency associated transcript (LAT), etc. Studies using neuronal cell lines have provided evidences demonstrating that liganded TR regulated viral gene expression via chromatin modification and controlled viral replication. …”
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    Effects of thyroid hormone on HSV-1 gene regulation: implications in the control of viral latency and reactivation
  14. 1954
    “…In the present study we observed that exposure of normal mitogenically stimulated lymphocytes or tumor cell lines A549, TK6 and A431 to metformin, the specific activator of 5'AMP-activated protein kinase (AMPK) and an inhibitor of mTOR signaling, resulted in attenuation of constitutive H2AX phosphorylation and ATM activation. …”
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    Genome protective effect of metformin as revealed by reduced level of constitutive DNA damage signaling
  15. 1955
    “…The quantification of DCE-MRI is preferable; therefore, many compartment model analyses have been proposed. The Toft and Kermode (TK) model is one of the most popular compartment models, which provide information about the influx forward volume transfer constant from plasma into the extravascular-extracellular space (EES) and the fractional volume of EES per unit volume of tissue is used in many clinical studies. …”
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    The Principal of Dynamic Contrast Enhanced MRI, the Method of Pharmacokinetic Analysis, and Its Application in the Head and Neck Region
  16. 1956
    “…In particular, mutations of the EGFR TK domain have been shown to increase the sensitivity of the EGFR to exogenous growth factors and, at the same time, to EGFR TKIs such as gefitinib. …”
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    Optimizing response to gefitinib in the treatment of non-small-cell lung cancer
  17. 1957
    “…In this study, seven luciferase expression vectors, which contained potential mouse apolipoprotein C2 gene promoters, were constructed and co-transfected with pRL-TK into HEK293T cells to investigate apolipoprotein C2 promoter activity. …”
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    Cloning and characterization of an apolipoprotein C2 promoter in the mouse central nervous system
  18. 1958
    por Glaab, Enrico, Schneider, Reinhard
    Publicado 2015
    “…Availability and implementation: Freely available at http://www.repexplore.tk Contact: enrico.glaab@uni.lu Supplementary information: Supplementary data are available at Bioinformatics online.…”
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    RepExplore: addressing technical replicate variance in proteomics and metabolomics data analysis
  19. 1959
    “…The abundance of Ncs2p and Ncs6p, two members of the URM1 pathway responsible for the thiolation of wobble uridines in cytoplasmic tRNAs tK(UUU), tQ(UUG) and tE(UUC), is down-regulated in a proteasomal dependent fashion. …”
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    Protein degradation and dynamic tRNA thiolation fine-tune translation at elevated temperatures
  20. 1960
    por Dissous, Colette
    Publicado 2015
    “…They contain an extracellular Venus FlyTrap module similar to the ligand-binding domain of G protein-coupled receptors of class C and an intracellular TK domain similar to that of insulin receptors. …”
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    Venus Kinase Receptors at the Crossroads of Insulin Signaling: Their Role in Reproduction for Helminths and Insects
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