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153861por Jolliffe, David A, Holt, Hayley, Greenig, Matthew, Talaei, Mohammad, Perdek, Natalia, Pfeffer, Paul, Vivaldi, Giulia, Maltby, Sheena, Symons, Jane, Barlow, Nicola L, Normandale, Alexa, Garcha, Rajvinder, Richter, Alex G, Faustini, Sian E, Orton, Christopher, Ford, David, Lyons, Ronan A, Davies, Gwyneth A, Kee, Frank, Griffiths, Christopher J, Norrie, John, Sheikh, Aziz, Shaheen, Seif O, Relton, Clare, Martineau, Adrian R“…PARTICIPANTS: 6200 people aged ≥16 years who were not taking vitamin D supplements at baseline. INTERVENTIONS: Offer of a postal finger prick test of blood 25(OH)D concentration with provision of a six month supply of lower dose vitamin D (800 IU/day, n=1550) or higher dose vitamin D (3200 IU/day, n=1550) to those with blood 25(OH)D concentration <75 nmol/L, compared with no offer of testing or supplementation (n=3100). …”
Publicado 2022
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153862por Li, Gaojie, Gu, Yuanxia, Zou, Qin, Wang, Yiyi, Xiao, Yue, Xia, Dengmei, Zhan, Tongying, Zhou, Xingli, Wang, Qian, Yan, Wei, Li, Wei“…Based on drug prices during our study period and without taking into consideration access to health insurance, ADA was more cost-effective in real-world practice. …”
Publicado 2022
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153863por Shannon, Oliver M., Allen, Jason D., Bescos, Raul, Burke, Louise, Clifford, Tom, Easton, Chris, Gonzalez, Javier T., Jones, Andrew M., Jonvik, Kristin L., Larsen, Filip J., Peeling, Peter, Piknova, Barbora, Siervo, Mario, Vanhatalo, Anni, McGawley, Kerry, Porcelli, Simone“…It is recommended that athletes looking to benefit from dietary nitrate supplementation should consume 8–16 mmol nitrate acutely or 4–16 mmol/day nitrate chronically (with the final dose ingested 2–4 h pre-exercise) to maximise ergogenic effects, taking into consideration that, from a safety perspective, athletes may be best advised to increase their intake of nitrate via vegetables and vegetable juices. …”
Publicado 2022
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153864por Lau, Vincent I., Fowler, Robert, Pinto, Ruxandra, Tremblay, Alain, Borgia, Sergio, Carrier, François M., Cheng, Matthew P., Conly, John, Costiniuk, Cecilia T., Daley, Peter, Duan, Erick, Durand, Madeleine, Fontela, Patricia S., Farjou, George, Fralick, Mike, Geagea, Anna, Grant, Jennifer, Keynan, Yoav, Khwaja, Kosar, Lee, Nelson, Lee, Todd C., Lim, Rachel, O’Neil, Conar R., Papenburg, Jesse, Semret, Makeda, Silverman, Michael, Sligl, Wendy, Somayaji, Ranjani, Tan, Darrell H.S., Tsang, Jennifer L.Y., Weatherald, Jason, Yansouni, Cedric Philippe, Zarychanski, Ryan, Murthy, Srinivas“…METHODS: Patients with COVID-19 in Canadian hospitals from Aug. 14, 2020, to Apr. 1, 2021, were randomly assigned to receive remdesivir plus usual care versus usual care alone. Taking a public health care payer’s perspective, we collected in-hospital outcomes and health care resource utilization alongside estimated unit costs in 2020 Canadian dollars over a time horizon from randomization to hospital discharge or death. …”
Publicado 2022
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153865por Ssemwogerere, Arnold, Kamya, Javilla Kakooza, Nuwasasira, Lillian, Ahura, Claire, Isooba, Derrick Isaac, Wakida, Edith K., Obua, Celestino, Migisha, Richard“…LTFU was considered for those who were not taking ART refills for a period of ≥ 3 months. We abstracted demographic and clinical data from medical records at the selected clinics. …”
Publicado 2022
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153866por Dreher, Annegret, Yusuf, Rita, Ashraf, Hasan, Ahmed, Syed A. K. Shifat, Strümpell, Christian, Loerbroks, Adrian“…We also found high levels of social support, vertical trust and beneficial leadership (i.e., supervisors taking decisions free of bias). Garment workers frequently suffered from health complaints, first and foremost headache (68.3%), cold (55.3%), and back pain (50.7%). …”
Publicado 2022
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153867por SefidHaji, Somayeh, Aziznejadroshan, Parvin, Mojaveri, Mohsen Haghshenas, Nikbakht, Hossein-Ali, Qujeq, Durdi, Amiri, Seyedeh Roghieh Jafarian“…Finally, the results of ANCOVA analysis for the effects of the intervention, taking into account the baseline values, showed that the intervention was effective and had the greatest effect on cholesterol levels. …”
Publicado 2022
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153868por Wang, Zhao, Zhang, Sudong, Zhang, Xiaoyu, Liu, Li, Zhou, Lukun, Shen, Yuyan, Zhang, Rongli, He, Yi, Yang, Donglin, Jiang, Erlie, Feng, Xiaoming, Zhou, Jiaxi, Cheng, Tao, Han, Mingzhe, Feng, Sizhou“…RESULTS: Our study showed that the proportion of MAIT cells in grafts was not different from normal controls, but the CD4/8 subsets were altered. Taking the median of the proportion and number of MAIT cells in the graft as the threshold, the results showed that the incidence of grade B-D aGVHD in patients with MAIT cell proportion ≥ 3.03% was significantly higher than that in patients with MAIT cell proportion < 3.03% (56.3%, 95% CI 37.1–71.2 versus 23.1%, 95% CI 13.8–46.2; P = 0.038).The number of MAIT cells in the graft was not associated with aGVHD development (P = 0.173), however, when the graft contained more CD4 positive, CD8 positive, and CD4/CD8 double-positive MAIT cells, the incidence of aGVHD was significantly increased (P = 0.019, P = 0.035 and P = 0.027, respectively). …”
Publicado 2022
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153869“…The intervention consisted of 8 weeks of 20–40 minutes AT protocol at 60–75% HR(max) 3 sessions/week and taking 50,000 IU of Vit D supplement once a week. …”
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153870por Gao, Bo, Li, Xiangrui, Chen, Wenqing, Wang, Shu’an, He, Jian, Liu, Yu, Ding, Chao, Chen, Xiaotian“…Identifying visceral obesity and taking proper actions in gastrointestinal cancers are helpful for overall tumor prognosis.…”
Publicado 2022
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153871“…Unfortunately, writing a useful label function requires substantial error analysis and is a nontrivial task that takes multiple days per function. This bottleneck makes populating a knowledge graph with multiple nodes and edge types practically infeasible. …”
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153872por Qin, Cheng, Li, Tianhao, Wang, Yuanyang, Zhao, Bangbo, Li, Zeru, Li, Tianyu, Yang, Xiaoying, Zhao, Yutong, Wang, Weibin“…In WGCNA, 14 hub genes (COL5A1, FN1, THBS2, etc.) were positively related to high LNR, 104 hub genes (FFAR1, SCG5, TMEM63C, etc.) were negatively related to high LNR. After taking the intersection with GSE101448, 13 genes (CDK5R2, SYT7, CACNA2D2, etc.) which might prevent lymph node metastasis were further selected. …”
Publicado 2022
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153873por Mengesha, Melkamu Merid, Embibel, Mulugeta, Gobena, Tesfaye, Tunje, Abayneh, Jerene, Degu, Hallström, Inger Kristensson“…Good adherence was defined based on a past 30-day physician adherence evaluation of taking ≥ 95% of the prescribed doses. Binary logistic regression was used to identify factors associated with non-adherence to ART. …”
Publicado 2022
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153874por Ndaki, Pendo M., Mushi, Martha F., Mwanga, Joseph R., Konje, Eveline T., Mugassa, Stella, Manyiri, Msilikale W., Mwita, Stanley M., Ntinginya, Nyanda E., Mmbaga, Blandina T., Keenan, Katherine, Sabiiti, Wilber, Kesby, Mike, Benitez-Paez, Fernando, Sandeman, Alison, Holden, Matthew T. G., Mshana, Stephen E.“…Female clients were more likely than male to be asked if they were taking other medications (27.2% vs 9.8%), or had seen a doctor (27.8% vs 14.7%), and more likely to be advised to consult a doctor (21.6% vs 9.0%); pharmacies addressed these issues more often than ADDOs (17.7% vs 13.2, 23.9% vs 16.6%, 17.7 vs 10.9% respectively). …”
Publicado 2022
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153875por Madede, Tavares, Damasceno, Albertino, Lunet, Nuno, Augusto, Orvalho, Silva-Matos, Carla, Beran, David, Levitt, Naomi“…Only 10% of people with diabetes were aware of their disease, and only 44% of those taking oral glucose-lowering drugs. The prevalence of IFG over time [2.0% (95CI: 1.1-3.5) vs 4.8% (95CI: 3.6-6.3)] and diabetes [2.9% (95CI: 2.0-4.2) vs 7.4% (95CI: 5.5-10.0)] were more than twofold higher in 2014/2015 than in 2005. …”
Publicado 2022
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153876por Mukamba, Njekwa, Sharma, Anjali, Mwamba, Chanda, Nyirenda, Herbert, Foloko, Marksman, Lumbo, Kasapo, Christopoulos, Katerina, Simbeza, Sandra, Sikombe, Kombatende, Holmes, Charles B., Geng, Elvin H., Sikazwe, Izukanji, Bolton-Moore, Carolyn, Beres, Laura K.“…Patients emphasized that COVID-19 restrictions led to loss of employment and household income, exacerbating poverty and difficulties in taking ART. At individual level, most participants felt motivated to stay healthy during COVID-19 by ART adherence and regular laboratory monitoring. …”
Publicado 2022
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153877“…Group 1 enrolled patients receiving oral rivaroxaban (RA) at 10 mg, Group 2 included patients who received subcutaneous Dalteparin sodium at 2500 IU, while Group 3 included patients taking oral aspirin (ASA) at 100 mg. Patients in all the three groups received treatment once a day for 30 days at 12 h postoperatively. …”
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153878por Lou, Yunlong, Chen, Dandan, Lin, Zheng, Sun, Jianda, Song, Li, Chen, Wenzhong, Zhang, Ming, Chen, Yibiao“…Multivariate analysis showed that NTR was an independent influencing factor of OS (HR 3.00, 95% CI 1.06–8.4, P = 0.038), LPFS (HR 3.08, 95% CI 1.27–7.50, P = 0.013), and DMFS (HR 1.84, 95% CI 0.99–3.42, P = 0.054). Taking OS as the main observation point, the best cut-off point of NTR was 0.95. …”
Publicado 2022
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153879“…Though evidence is lacking; especially in developing countries like Ethiopia, the potential health impact of E. coli O157:H7 can be high where food production, handling and consumption is often taking place under unhygienic conditions. In Ethiopia, studies reported E. coli and E. coli O157: H7 from food of animal origin, mainly meat and milk, and also animal surfaces and feces. …”
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153880por Saita, Sayambhu, Roobsoong, Wanlapa, Khammaneechan, Patthanasak, Sukchan, Phnom, Lawpoolsri, Saranath, Sattabongkot, Jetsumon, Cui, Liwang, Okanurak, Kamolnetr, Phuanukoonnon, Suparat, Parker, Daniel M.“…Five key themes emerged from the qualitative analyses: concern about side effects from taking PQ; disbelief that malaria could be eliminated in this setting; low overall concern about malaria infections; misunderstandings about malaria; and a general need to tailor public health efforts for this unique context. …”
Publicado 2023
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