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  1. 154721
    “…In this paper, we try to predict survival outcomes via early changes in the DCE-MRI biomarkers in participants with advanced HCC after 2nd-line targeted therapy following sorafenib failure, taking data from two different prospective clinical trials. …”
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    Early Changes in DCE-MRI Biomarkers May Predict Survival Outcomes in Patients with Advanced Hepatocellular Carcinoma after Sorafenib Failure: Two Prospective Phase II Trials
  2. 154722
    “…Compared to 13,059 patients injured by high-energy transfer (HE cohort), the those injured through low-energy falls (LE cohort) were older (LE cohort, median 74 [IQR 56 to 84] years, versus HE cohort, median 42 [IQR 25 to 60] years; p < 0.001), more often female (LE cohort, 50% [95% CI 48% to 51%], versus HE cohort, 32% [95% CI 31% to 34%]; p < 0.001), more frequently taking pre-injury anticoagulants or/and platelet aggregation inhibitors (LE cohort, 44% [95% CI 42% to 45%], versus HE cohort, 13% [95% CI 11% to 14%]; p < 0.001), and less often presenting with moderately or severely impaired conscious level (LE cohort, 7.8% [95% CI 5.6% to 9.8%], versus HE cohort, 10% [95% CI 8.7% to 12%]; p < 0.001), but had similar in-hospital mortality (LE cohort, 6.3% [95% CI 4.2% to 8.3%], versus HE cohort, 7.0% [95% CI 5.3% to 8.6%]; p = 0.83). …”
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    The burden of traumatic brain injury from low-energy falls among patients from 18 countries in the CENTER-TBI Registry: A comparative cohort study
  3. 154723
    “…The risk for adverse bleeding events while taking chemoprophylaxis and requires further research. …”
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    Venous thromboembolism prophylaxis after ambulatory arthroscopic knee surgery: a systematic review and meta-analysis of incidence and risk factors (109)
  4. 154724
    por Simpson-Yap, Steve, De Brouwer, Edward, Kalincik, Tomas, Rijke, Nick, Hillert, Jan A., Walton, Clare, Edan, Gilles, Moreau, Yves, Spelman, Tim, Geys, Lotte, Parciak, Tina, Gautrais, Clement, Lazovski, Nikola, Pirmani, Ashkan, Ardeshirdavanai, Amin, Forsberg, Lars, Glaser, Anna, McBurney, Robert, Schmidt, Hollie, Bergmann, Arnfin B., Braune, Stefan, Stahmann, Alexander, Middleton, Rodden, Salter, Amber, Fox, Robert J., van der Walt, Anneke, Butzkueven, Helmut, Alroughani, Raed, Ozakbas, Serkan, Rojas, Juan I., van der Mei, Ingrid, Nag, Nupur, Ivanov, Rumen, Sciascia do Olival, Guilherme, Dias, Alice Estavo, Magyari, Melinda, Brum, Doralina, Mendes, Maria Fernanda, Alonso, Ricardo N., Nicholas, Richard S., Bauer, Johana, Chertcoff, Aníbal Sebastián, Zabalza, Anna, Arrambide, Georgina, Fidao, Alexander, Comi, Giancarlo, Peeters, Liesbet
    Publicado 2021
    “…BACKGROUND AND OBJECTIVES: People with multiple sclerosis (MS) are a vulnerable group for severe coronavirus disease 2019 (COVID-19), particularly those taking immunosuppressive disease-modifying therapies (DMTs). …”
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    Associations of Disease-Modifying Therapies With COVID-19 Severity in Multiple Sclerosis
  5. 154725
    “…Interleukin-6 and IL-1b blockers were used as pathogenetic therapy to control hypercytokinemia. Taking into account grade 4 neutropenia, the dose of interleukin blockers was reduced. …”
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    Treatment and in-Hospital Overall Survival in Hematological Patients with Grade 4 Neutropenia and Coronavirus Infection
  6. 154726
    “…Methods: A total of 846 patients were retrospectively evaluated to determine if they were treated with guideline-appropriate anticoagulation while hospitalized with COVID-19, as well as if they developed venous or arterial thrombotic events, or major or minor bleeds. 317 patients were excluded for taking therapeutic anticoagulation prior to admission, or for having a COVID-19 diagnosis >7 days after admission. …”
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    An Inpatient COVID-19 Prophylaxis Protocol and Its Outcomes: Adherence and Efficacy
  7. 154727
    “…Bleeding was reported in 276 (7%) pts with median age of 70years; incidence was 6.6 % in females and 7.6 % in males, 6.5% in non-Hispanic white pts, 8.2 % in non-Hispanic Black pts, and 7.8 % in Hispanic pts. 74% had solid cancer and 29% had hematologic malignancies, 33% had received anti-cancer therapy in preceding 30 days, and 8% had surgery within 4weeks. In pts taking antiplatelet or anticoagulant medications at baseline, 7.2% developed bleeding. …”
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    Bleeding Complications in Patients with Cancer and COVID 19- Analysis from the COVID 19and Cancer Consortium (CCC19) Registry
  8. 154728
    “…CONCLUSION: In the context of the PPPM/3PM, the employment of the described pipeline through the provided webservice, together with the ongoing SARS-CoV-2 genomic sequencing, would help to predict the transmissibility of new variants sequenced from future patients, depending on SARS-CoV-2 genomic sequencing activities and on the specific amino acid replacement and/or on its location on the SARS-CoV-2 spike RBD, to put in play all the possible counteractions for preventing the most deleterious scenarios of new outbreaks, taking into consideration that a greater transmissibility has not to be necessarily related to a more severe manifestation of the disease. …”
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    Modeling SARS-CoV-2 spike/ACE2 protein–protein interactions for predicting the binding affinity of new spike variants for ACE2, and novel ACE2 structurally related human protein targets, for COVID-19 handling in the 3PM context
  9. 154729
    “…We can hypothesise that attempts to innovate the biomechanics of the treatments is missing the fundamental issue surrounding SpA back pain highlighted by NASS; TTD takes too long for too many.  There is a feasible argument therefore that it is the structures of how we operate as HCPs that is reducing the efficacy of said treatments. …”
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    O10 Multi-disciplinary working in SpA diagnosis: case study
  10. 154730
    “…The main source for vitamin D is the body’s skin which absorbs the sun’s ultraviolet rays and convert them into vitamin D; at the same time, deficiency can occur or people may not get enough supplementation; this occurs mainly in old age, not taking healthy food, or have darker skin, and this deficient cases can raise the risk of severe COVID-19 if infected. …”
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    Cholecalciferol level and its impact on COVID-19 patients
  11. 154731
    “…BACKGROUND: Oral pre-exposure prophylaxis has been introduced in more than 70 countries, including many in sub-Saharan Africa, but women experience considerable barriers to daily pill-taking, such as stigma, judgement, and the fear of violence. …”
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    Cabotegravir for the prevention of HIV-1 in women: results from HPTN 084, a phase 3, randomised clinical trial
  12. 154732
    “…In accord herewith, one may enhance the reaction rate by adding AMP(2−) to the [Cu(2)(ATP)](2)(OH)(−) solution, as this leads to the formation of mixed stacked Cu(3)(ATP)(AMP)(OH)(−) species, in which AMP(2−) takes over the structuring role, while the other “half” of the molecule undergoes dephosphorylation. …”
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    Coordination Chemistry of Nucleotides and Antivirally Active Acyclic Nucleoside Phosphonates, including Mechanistic Considerations †
  13. 154733
    “…The transabdominal selective reduction of twin pregnancy should be considered for a lower rate of miscarriage or premature delivery if the reduction week takes place earlier in pregnancy. The rate of preterm delivery was the lowest when transabdominal selective reduction was completed before 22 weeks of gestation. …”
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    Correlation analysis of adverse outcomes for the selective reduction of twin pregnancies
  14. 154734
    “…. >50,000 BDT: AOR = 0.727, 95% CI = 0.540, 0.979; p = 0.036), and who were taking larger meals/snacks (increased vs. unchanged: AOR = 2.806, 95% CI = 2.190, 3.596; p < 0.001) and had conflicts/arguments with others (no vs. yes: AOR = 0.524, 95% CI = 0.418, 0.657; p < 0.001), were significantly more physically inactive. …”
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    Impact of Prolonged COVID-19 Lockdown on Body Mass Index, Eating Habits, and Physical Activity of University Students in Bangladesh: A Web-Based Cross-Sectional Study
  15. 154735
    “…Exploring and integrating molecular techniques into national surveillance programme could improve the sensitivity of surveillance system and provide guidance on taking actions against schistosomiasis. GRAPHICAL ABSTRACT: [Image: see text] SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s40249-022-00995-9.…”
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    Molecular evidence on the presence of Schistosoma japonicum infection in snails along the Yangtze River, 2015–2019
  16. 154736
    “…The first visit consisted of medical history taking and explaining the study design. On the second visit, the participants were subjected to an incremental test to determine their maximal rate of oxygen consumption (VO(2max)) that was required to prescribe the intensity of the submaximal exercise protocol. …”
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    A Single Bout of Fatiguing Aerobic Exercise Induces Similar Pronounced Immunological Responses in Both Sexes
  17. 154737
    por Long, Guangli
    Publicado 2022
    “…BACKGROUND: Auricularia auricula grows in high environmental conditions and takes a long time to produce. The environmental quality control of Auricularia auricula has gradually become the biggest bottleneck and obstacle restricting its quality production. …”
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    DESIGN OF INDOOR AGARIC CULTIVATION MONITORING DEVICE BASED ON INTERNET OF THINGS AND EMOTIONAL BEHAVIOR CHANGE
  18. 154738
    por Long, Chang, Li, Jianghao
    Publicado 2022
    “…RESEARCH OBJECTS AND METHODS: Using the method of literature research and taking western patriotism education as the comparative object, this study makes a multi-dimensional and multi-dimensional comparative study on the characteristics of Chinese patriotism education, including the importance, main contents, development scope, cultural background, methods and approaches of patriotism education, as well as the main psychological concepts, and analyzes the similarities and differences between Chinese and Western patriotism education. …”
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    ANALYSIS AND INTERNATIONAL COMPARISON OF THE CHANGE OF PATRIOTIC EDUCATION EMOTION AND BEHAVIOR IN THE ERA OF SELF MEDIA
  19. 154739
    “…RESEARCH OBJECTS AND METHODS: This paper adopts WHOQOL-BREF questionnaire and takes netizens as respondents. The questionnaire was anonymously distributed to 8 provinces (cities) including Beijing, Shanghai, Fujian, Guangdong, Jiangsu, Zhejiang, Anhui and Jiangxi. …”
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    STUDY ON GENDER DIFFERENCES OF INTERNET USERS' PSYCHOLOGICAL AND EMOTIONAL BEHAVIOR CHANGES BASED ON PLS-SEM
  20. 154740
    “…Then, considering the fuzziness and uncertainty of qualitative and quantitative description of evaluation indicators, the comprehensive evaluation method based on cloud model is used to evaluate the vulnerability risk of collaborative innovation network. Finally, taking the vulnerability risk analysis of project product collaborative innovation network of enterprise a as an example, the risk assessment analysis is carried out. …”
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    RESEARCH ON VULNERABILITY RISK ASSESSMENT OF COLLABORATIVE INNOVATION NETWORK DRIVEN BY MULTI-AGENT EMOTIONAL BEHAVIOR
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