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121por Gatza, Catherine E., Elderbroom, Jennifer L., Oh, Sun Young, Starr, Mark D., Nixon, Andrew B., Blobe, Gerard C.“…Inhibition of TβRIII shedding through treatment with TAPI-2 or expression of a non-shedding TβRIII mutant rescued TβRIII mediated inhibition of BMP induced Smad1/5/8 phosphorylation and BMP induced migration and/or invasion in both in normal mammary epithelial cells and breast cancer cells. …”
Publicado 2014
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122por Deora, Arun, Hegde, Subramanya, Lee, Jacqueline, Choi, Chee-Ho, Chang, Qing, Lee, Cheryl, Eaton, Lucia, Tang, Hua, Wang, Dongdong, Lee, David, Michalak, Mark, Tomlinson, Medha, Tao, Qingfeng, Gaur, Nidhi, Harvey, Bohdan, McLoughlin, Shaun, Labkovsky, Boris, Ghayur, Tariq“…Here, we demonstrate biochemically that TmTNF is transiently expressed on the surface of lipopolysaccharide-stimulated primary human monocytes, macrophages, and monocyte-derived dendritic cells (DCs) and expression of TmTNF on the cell surface is enhanced following treatment of cells with TAPI-2, a TACE inhibitor. Importantly, binding of anti-TNFs to TmTNF on DCs results in rapid internalization of the anti-TNF/TmTNF complex first into early endosomes and then lysosomes. …”
Publicado 2017
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123“…Treatment with an NRG1-cleavage inhibitor (TAPI2) or an inhibitor of NRG1-binding (anti-HER3 antibody) reduced HER2 phosphorylation and partially mitigated stretch-induced permeability, with the upregulation of claudin-7. …”
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124por Karampatzakis, Alexandros, Brož, Petr, Rey, Camille, Önfelt, Björn, Cruz De Matos, Gabriela Dos Santos, Rycroft, Daniel, Ambrose, Ashley, Davis, Daniel M.“…Inhibition of CD16 shedding with TAPI-0 led to reduced detachment and serial killing. …”
Publicado 2021
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125por Spangenberg, Lucía, Guecaimburú, Rosario, Tapié, Alejandra, Vivas, Susana, Rodríguez, Soledad, Graña, Martín, Naya, Hugo, Raggio, VíctorEnlace del recurso
Publicado 2021
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126por Kagawa, Kumiko, Nakano, Ayako, Miki, Hirokazu, Oda, Asuka, Amou, Hiroe, Takeuchi, Kyoko, Nakamura, Shingen, Harada, Takeshi, Fujii, Shiro, Yata, Kenichiro, Ozaki, Shuji, Matsumoto, Toshio, Abe, Masahiro“…The DR4 levels in these conditioned media were reduced by TACE inhibition by the TACE inhibitor TAPI-0 as well as TACE siRNA. Conversely, the TACE inhibition restored surface levels of DR4 but not DR5 in these cells without affecting DR4 mRNA levels. …”
Publicado 2012
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127por Arenaccio, Claudia, Anticoli, Simona, Manfredi, Francesco, Chiozzini, Chiara, Olivetta, Eleonora, Federico, Maurizio“…Treatment with either TAPI-2, i.e., a specific inhibitor of the pro-TNFα-processing ADAM17 enzyme, or anti-TNFα Abs abolished HIV-1 activation. …”
Publicado 2015
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128por Miao, Kun, Zhou, Ling, Ba, Hongping, Li, Chenxi, Gu, Haiyan, Yin, Bingjiao, Wang, Jing, Yang, Xiang-ping, Li, Zhuoya, Wang, Dao Wen“…Suppressing TNF-α converting enzyme by TNF-α Protease Inhibitor-1 (TAPI-1) to increase endogenous tmTNF-α expression significantly alleviated TAC-induced cardiac hypertrophy. …”
Publicado 2020
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129por Adil, Muhammad, Lee, Keanchuan, Mohd Zaid, Hasnah, A. Shukur, M. Fadhllullah, Manaka, Takaaki“…The displacement tests were conducted in water-wet sandpacks at 95˚C, by employing crude oil from Tapis. Three tertiary recovery scenarios have been performed, including (i) SDBS surfactant flooding as a reference, (ii) ZnO-NFs flooding, and (iii) EM-assisted ZnO-NFs flooding. …”
Publicado 2020
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130por Huang, Kaichi, Jahani, Mojtaba, Gouzy, Jérôme, Legendre, Alexandra, Carrere, Sébastien, Lázaro-Guevara, José Miguel, González Segovia, Eric Gerardo, Todesco, Marco, Mayjonade, Baptiste, Rodde, Nathalie, Cauet, Stéphane, Dufau, Isabelle, Staton, S. Evan, Pouilly, Nicolas, Boniface, Marie-Claude, Tapy, Camille, Mangin, Brigitte, Duhnen, Alexandra, Gautier, Véronique, Poncet, Charles, Donnadieu, Cécile, Mandel, Tali, Hübner, Sariel, Burke, John M., Vautrin, Sonia, Bellec, Arnaud, Owens, Gregory L., Langlade, Nicolas, Muños, Stéphane, Rieseberg, Loren H.Enlace del recurso
Publicado 2023
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131por Martinez Palacios, Paulina, Jacquemot, Marie-Pierre, Tapie, Marion, Rousselet, Agnès, Diop, Mamoudou, Remoué, Carine, Falque, Matthieu, Lloyd, Andrew, Jenczewski, Eric, Lassalle, Gilles, Chévre, Anne-Marie, Lelandais, Christine, Crespi, Martin, Brabant, Philippe, Joets, Johann, Alix, KarineEnlace del recurso
Publicado 2019
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132por Sapoval, M., Gaultier, A.L., Del Giudice, C., Pellerin, O., Kassis-Chikhani, N., Lemarteleur, V., Fouquet, V., Tapie, L., Morenton, P., Tavitian, B., Attal, J.P.Enlace del recurso
Publicado 2020
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133por Monti, Dominique, Hubas, Cedric, Lourenço, Xavier, Begarin, Farid, Haouisée, Alexandre, Romana, Laurence, Lefrançois, Estelle, Jestin, Alexandra, Budzinski, Hélène, Tapie, Nathalie, Risser, Théo, Mansot, Jean-Louis, Keith, Philippe, Gros, Olivier, Lopez, Pascal-Jean, Lauga, BéatriceEnlace del recurso
Publicado 2020
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134“…The displacement tests were conducted in water-wet sandpacks at 95 °C, by employing crude oil from Tapis. Alumina nanofluids (Al(2)O(3)-NFs) of four different phases (α, κ, θ and γ) and particle sizes (25–94.3 nm) were prepared by dispersing 0.01 wt. % NPs in brine (3 wt. % NaCl) together with SDBS as a dispersant. …”
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135por Gbeasor-Komlanvi, F.A., Afanvi, K.A., Konu, Y.R., Agbobli, Y., Sadio, A.J., Tchankoni, M.K., Zida-Compaore, W.I.C., Nayo-Apetsianyi, J., Agoro, S., Lambokale, A., Nyametso, D., N'tapi, T., Aflagah, K., Mijiyawa, M., Ekouevi, D.K.Enlace del recurso
Publicado 2021
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136“…Inhibition of ADAM proteases with TAPI-0 resulted in reduced shedding of the sorting receptor SORT1, and an attenuated cytokine response suggesting a direct link between cell surface shedding and cytokine secretion rates.…”
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138por Liu, Qin-she, Wang, Hai-fang, Sun, An-ke, Huo, Xue-ping, Liu, Jin-lian, Ma, Shu-hui, Peng, Ning, Hu, Jun“…Furthermore, mechanistic investigation demonstrated that TNFR1-mediated IκBα degradation was reversed by the use of TAPI-0, an inhibitor of TNFα converting enzyme (TACE), suggesting the involvement of TACE in the modulation of surface TNFR1 level by AST. …”
Publicado 2014
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139por Yayama, Katsutoshi, Sasahara, Tomoya, Ohba, Hisaaki, Funasaka, Ayaka, Okamoto, Hiroshi“…Furthermore, a metalloproteinase inhibitor TAPI-0 [N-(R)-[2-(hydroxyaminocarbonyl) methyl]-4-methylpentanoyl-l-naphthylalanyl-l-alanine amide] and an inhibitor of heparin-binding EGF (CRM 197) not only abrogated the OVA-induced aortic contraction, but also OVA-induced EGFR and MYPT1 phosphorylation, suggesting the involvement of EGFR transactivation. …”
Publicado 2014
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140por Adil, Muhammad, Lee, Keanchuan, Mohd Zaid, Hasnah, Ahmad Latiff, Noor Rasyada, Alnarabiji, Mohamad Sahban“…Two-phase displacement experiments were performed in sandpacks under the water-wet condition at 95°C, with permeability in the range of 265–300 mD. A crude oil from Tapis oil field was employed; while ZnO nanofluids of two different particle sizes (55.7 and 117.1 nm) were prepared using 0.1 wt. % nanoparticles that dispersed into brine (3 wt. % NaCl) along with SDBS as a dispersant. …”
Publicado 2018
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