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  1. 233141
    “…BACKGROUND: Sperm DNA integrity is increasingly seen as a critical characteristic determining reproductive success, both in natural reproduction and in assisted reproductive technologies (ART). Despite this awareness, sperm DNA and nuclear integrity tests are still not part of routine examinations for either infertile men or fertile men wishing to assess their reproductive capacity. …”
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    Online Artículo Texto
    Sperm chromatin structure assay (SCSA(®)) and flow cytometry-assisted TUNEL assay provide a concordant assessment of sperm DNA fragmentation as a function of age in a large cohort of approximately 10,000 patients
  2. 233142
    por Cimini, Christiane Corrêa Rodrigues, Delfino-Pereira, Polianna, Pires, Magda Carvalho, Ramos, Lucas Emanuel Ferreira, Gomes, Angélica Gomides dos Reis, Jorge, Alzira de Oliveira, Fagundes, Ariovaldo Leal, Garcia, Bárbara Machado, Pessoa, Bruno Porto, de Carvalho, Cíntia Alcantara, Ponce, Daniela, Rios, Danyelle Romana Alves, Anschau, Fernando, Vigil, Flavia Maria Borges, Bartolazzi, Frederico, Grizende, Genna Maira Santos, Vietta, Giovanna Grunewald, Goedert, Giulia Maria dos Santos, Nascimento, Guilherme Fagundes, Vianna, Heloisa Reniers, Vasconcelos, Isabela Muzzi, de Alvarenga, Joice Coutinho, Chatkin, José Miguel, Machado Rugolo, Juliana, Ruschel, Karen Brasil, Zandoná, Liege Barella, Menezes, Luanna Silva Monteiro, de Castro, Luís César, Souza, Maíra Dias, Carneiro, Marcelo, Bicalho, Maria Aparecida Camargos, Cunha, Maria Izabel Alcântara, Sacioto, Manuela Furtado, de Oliveira, Neimy Ramos, Andrade, Pedro Guido Soares, Lutkmeier, Raquel, Menezes, Rochele Mosmann, Ribeiro, Antonio Luiz Pinho, Marcolino, Milena Soriano
    Publicado 2023
    “…BACKGROUND: Predicting the need for invasive mechanical ventilation (IMV) is important for the allocation of human and technological resources, improvement of surveillance, and use of effective therapeutic measures. …”
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    Online Artículo Texto
    Assessment of the ABC(2)-SPH risk score to predict invasive mechanical ventilation in COVID-19 patients and comparison to other scores
  3. 233143
    “…STUDY SELECTION CRITERIA: Case–control, cross-sectional, and longitudinal studies were included if they investigated the reliability or validity of various ultrasonography technologies (e.g., brightness-mode, motion-mode, shear wave elastography) in measuring the thickness, excursion, stiffness, or strain rate of any respiratory muscles. …”
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    Reliability and validity of ultrasonography in evaluating the thickness, excursion, stiffness, and strain rate of respiratory muscles in non-hospitalized individuals: a systematic review
  4. 233144
    “…In these situations, whole genome genotyping of orthologous shared single nucleotide polymorphism loci, discovered using next generation sequencing technologies, can provide very large data sets capable of estimating core phylogenetic relationships. …”
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    Phylogeographic reconstruction of a bacterial species with high levels of lateral gene transfer
  5. 233145
    “…CONCLUSIONS: These findings support the use of Web-based tools and mobile technologies to change dietary behavior. The combination of a fully automated Web-based planning tool with mobile text reminders led to lower self-reported consumption of high-fat foods and greater reductions in portion sizes than in a control condition. …”
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    Online Artículo Texto
    Exploratory Study of Web-Based Planning and Mobile Text Reminders in an Overweight Population
  6. 233146
    “…However, large sample numbers are a pre-requisite for the identification of genetic variants underlying complex traits and although technologies are improving rapidly, high-throughput sequencing of large numbers of complete individual genomes remains prohibitively expensive. …”
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    Online Artículo Texto
    Polymorphism discovery and allele frequency estimation using high-throughput DNA sequencing of target-enriched pooled DNA samples
  7. 233147
    “…BACKGROUND: Prevention of the onset of depression in adolescence may prevent social dysfunction, teenage pregnancy, substance abuse, suicide, and mental health conditions in adulthood. New technologies allow delivery of prevention programs scalable to large and disparate populations. …”
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    Online Artículo Texto
    MEMO—A Mobile Phone Depression Prevention Intervention for Adolescents: Development Process and Postprogram Findings on Acceptability From a Randomized Controlled Trial
  8. 233148
    “…This tool can be used as a reference resource for studies in different genetic backgrounds, and provides a framework for transferring genetic information when using different marker technologies. Combined with syntenic approaches, the consensus map will increase marker density in selected genomic regions and will be useful for future faba bean molecular breeding applications.…”
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    Online Artículo Texto
    A reference consensus genetic map for molecular markers and economically important traits in faba bean (Vicia faba L.)
  9. 233149
    “…Genome-wide profiling has become a powerful method for assessing immune responses on a systems scale, but technologies that can measure the plasma proteome still face considerable challenges. …”
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    A transcriptomic reporter assay employing neutrophils to measure immunogenic activity of septic patients’ plasma
  10. 233150
    “…METHODS: In this system, 4 × 10(5) cells/ml of UCB-MNCs were inoculated in serum-free Stemspan® medium (Stemcell technologies, vancouver, BC, Canada) supplied with standard basal cytokine combination of 100 ng/ml SCF, 50 ng/ml FL and 100 ng/ml TPO and supported by a bone marrow mesenchymal stromal cell layer. …”
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    Online Artículo Texto
    Low-dose insulin-like growth factor binding proteins 1 and 2 and angiopoietin-like protein 3 coordinately stimulate ex vivo expansion of human umbilical cord blood hematopoietic stem cells as assayed in NOD/SCID gamma null mice
  11. 233151
    “…However, despite widespread support for the use of mobile health technologies, evidence for its role in health care is sparse. …”
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    Mobile Phone Intervention Reduces Perinatal Mortality in Zanzibar: Secondary Outcomes of a Cluster Randomized Controlled Trial
  12. 233152
    “…BACKGROUND: Dramatic improvements in DNA-sequencing technologies and computational analyses have led to wide use of whole exome sequencing (WES) to identify the genetic basis of Mendelian disorders. …”
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    FLAGS, frequently mutated genes in public exomes
  13. 233153
    por Gaye, Amadou, Marcon, Yannick, Isaeva, Julia, LaFlamme, Philippe, Turner, Andrew, Jones, Elinor M, Minion, Joel, Boyd, Andrew W, Newby, Christopher J, Nuotio, Marja-Liisa, Wilson, Rebecca, Butters, Oliver, Murtagh, Barnaby, Demir, Ipek, Doiron, Dany, Giepmans, Lisette, Wallace, Susan E, Budin-Ljøsne, Isabelle, Oliver Schmidt, Carsten, Boffetta, Paolo, Boniol, Mathieu, Bota, Maria, Carter, Kim W, deKlerk, Nick, Dibben, Chris, Francis, Richard W, Hiekkalinna, Tero, Hveem, Kristian, Kvaløy, Kirsti, Millar, Sean, Perry, Ivan J, Peters, Annette, Phillips, Catherine M, Popham, Frank, Raab, Gillian, Reischl, Eva, Sheehan, Nuala, Waldenberger, Melanie, Perola, Markus, van den Heuvel, Edwin, Macleod, John, Knoppers, Bartha M, Stolk, Ronald P, Fortier, Isabel, Harris, Jennifer R, Woffenbuttel, Bruce HR, Murtagh, Madeleine J, Ferretti, Vincent, Burton, Paul R
    Publicado 2014
    “…DataSHIELD provides a novel technological solution that can circumvent some of the most basic challenges in facilitating the access of researchers and other healthcare professionals to individual-level data. …”
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    DataSHIELD: taking the analysis to the data, not the data to the analysis
  14. 233154
    “…There is an urgent need to identify or develop new insecticides and technologies to limit the vulnerability of ITNs to insecticide resistance.…”
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    A cohort study of the effectiveness of insecticide-treated bed nets to prevent malaria in an area of moderate pyrethroid resistance, Malawi
  15. 233155
    “…CONCLUSIONS: This study explores the use of widely-available text messaging and voice technologies for insulin titration. We aim to show that remote insulin titration is clinically effective, feasible, satisfactory, and cost saving for low-income patients in a busy, urban clinic. …”
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    The Mobile Insulin Titration Intervention (MITI) for Insulin Glargine Titration in an Urban, Low-Income Population: Randomized Controlled Trial Protocol
  16. 233156
    “…CLE was performed soon after resection with the Cellvizio® Endomicroscopy System (Mauna Kea Technologies, Paris, France), by using a Coloflex UHD-type probe; intravenous fluorescein was used as contrast-enhancing agent. …”
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    Confocal laser endomicroscopy in breast surgery: a pilot study
  17. 233157
    “…Thus, characterizing genome-wide the transcriptional changes that occur after memory acquisition and retrieval is of broad interest and importance. Genome-wide technologies are commonly used to interrogate transcriptional changes in discovery-based approaches. …”
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    Memory acquisition and retrieval impact different epigenetic processes that regulate gene expression
  18. 233158
    “…BACKGROUND: The invention of high throughput sequencing technologies has led to the discoveries of hundreds of thousands of genetic variants associated with thousands of human diseases. …”
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    Online Artículo Texto
    Disease-associated variants in different categories of disease located in distinct regulatory elements
  19. 233159
    “…As women worldwide embrace modern technologies, e-health innovations may provide opportune and convenient methods of implementing programs and strategies to target PA in an effort to improve MVPA levels and cardiometabolic health. …”
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    Online Artículo Texto
    E-health physical activity interventions and moderate-to-vigorous intensity physical activity levels among working-age women: a systematic review protocol
  20. 233160
    “…BACKGROUND: In the healthcare sector, it is crucial to identify sustainable strategies in order to allow the introduction and use of innovative technologies. Now, and over the next few years, the expiry of patents for different antiretroviral drugs offers an opportunity to increase the efficiency of resources allocation. …”
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    New Highly Active Antiretroviral drugs and generic drugs for the treatment of HIV infection: a budget impact analysis on the Italian National Health Service (Lombardy Region, Northern Italy)
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