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  1. 233301
    “…Here we report chronic SARS-CoV-2 with reduced sensitivity to neutralising antibodies in an immune suppressed individual treated with convalescent plasma, generating whole genome ultradeep sequences by both short and long read technologies over 23 time points spanning 101 days. Although little change was observed in the overall viral population structure following two courses of remdesivir over the first 57 days, N501Y in Spike was transiently detected at day 55 and V157L in RdRp emerged. …”
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    Neutralising antibodies in Spike mediated SARS-CoV-2 adaptation
  2. 233302
    “…On the other hand, the advances in sequencing technologies, together with community efforts, have made publicly available a large amount of genomic data. …”
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    Online Artículo Texto
    Explore the genetics of weedy traits using rice 3K database
  3. 233303
    “…BACKGROUND: Recent DNA/RNA sequencing and other multi-omics technologies have advanced the understanding of the biology and pathophysiology of AD, yet there is still a lack of disease-modifying treatments for AD. …”
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    Online Artículo Texto
    AlzGPS: a genome-wide positioning systems platform to catalyze multi-omics for Alzheimer’s drug discovery
  4. 233304
    “…The comments revealed 7 different categories of user requirements with noticeable differences between those of physicians and nurses: technological challenges, keep track of time, documentation and history, disturbing element, improvement areas: functions, improvement areas: design, and better guidance. …”
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    Mobile App Support for Cardiopulmonary Resuscitation: Development and Usability Study
  5. 233305
    “…The framework provides the technological foundation for improving the clinical workflow and can serve as a biomarker extraction tool in cerebrovascular diseases.…”
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    Online Artículo Texto
    BRAVE-NET: Fully Automated Arterial Brain Vessel Segmentation in Patients With Cerebrovascular Disease
  6. 233306
    “…We assess the improvements in lesion detectability and image quality between three generations of PET scanners with different detector technologies. The results are used to suggest an optimized protocol. …”
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    Comparing lesion detection efficacy and image quality across different PET system generations to optimize the iodine-124 PET protocol for recurrent thyroid cancer
  7. 233307
    por Chen, Hao, Lu, Yan, Lu, Dongsheng, Xu, Shuhua
    Publicado 2021
    “…The advance of next-generation sequencing (NGS) technologies increasingly improves the resolution of the non-recombining region of the Y-chromosome (NRY). …”
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    Y-LineageTracker: a high-throughput analysis framework for Y-chromosomal next-generation sequencing data
  8. 233308
    “…BACKGROUND: The retinal and cerebral microvasculature share similar embryological origins and physiological characteristics. Improved imaging technologies provide opportunistic non-invasive assessment of retinal microvascular parameters (RMPs) against cognitive outcomes. …”
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    Online Artículo Texto
    Retinal microvascular parameters are not significantly associated with mild cognitive impairment in the Northern Ireland Cohort for the Longitudinal Study of Ageing
  9. 233309
    “…INTRODUCTION: Deep Learning (DL) and Artificial Intelligence (AI) have become widespread due to the advanced technologies and availability of digital data. Supervised learning algorithms have shown human-level performance or even better and are better feature extractor-quantifier than unsupervised learning algorithms. …”
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    Online Artículo Texto
    Evaluating the Viability of a Smartphone-Based Annotation Tool for Faster and Accurate Image Labelling for Artificial Intelligence in Diabetic Retinopathy
  10. 233310
    “…Discussion: The STAR-C research programme will address the knowledge and practice research gaps in the use of information technologies in health promotion and non-communicable disease (NCD) prevention programmes in order to narrow the health inequality gaps. …”
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    Sustainable Behavior Change for Health Supported by Person-Tailored, Adaptive, Risk-Aware Digital Coaching in a Social Context: Study Protocol for the STAR-C Research Programme
  11. 233311
    “…Five types of NC demands can be identified: demands relating to daily life, alternative medicine, structure of the treatment pathway, administrative and logistic assistance and demands relating to new technologies. CONCLUSIONS: This study shows that HCOs should be able to consider non-clinical demands in addition to those referring to clinical needs. …”
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    What matters to patients? A mixed method study of the importance and consideration of oncology patient demands
  12. 233312
    “…Focus group participants cited obstacles to implementing Success strategies (e.g., providing feedback), including difficulty in providing feedback in large courses, lacking time and assistant teachers, limited knowledge of technologies, and lacking skills related to guiding effective student peer feedback. …”
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    Faculty’s attitudes and perceptions related to applying motivational principles to their teaching: a mixed methods study
  13. 233313
    “…CONCLUSIONS: We show that a hybrid approach of integrating multiple sequencing technologies with chromosome conformation information results in an accurate de novo chromosome-scale assembly of O. dioica’s highly polymorphic genome. …”
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    Telomere-to-telomere assembly of the genome of an individual Oikopleura dioica from Okinawa using Nanopore-based sequencing
  14. 233314
    “…In such high-field magnets, the design pre-stress can reach considerable values (150–200 MPa) and, since Nb(3)Sn is a brittle compound, this can constitute a technological difficult challenge. Due to the significant impact that a transverse load can have on the performances of a Nb(3)Sn magnet, CERN has launched a campaign of critical current measurements of reacted and impregnated Nb(3)Sn cables subjected to transverse pressure up to about 210 MPa. …”
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    On the mechanisms governing the critical current reduction in Nb(3)Sn Rutherford cables under transverse stress
  15. 233315
    “…Moreover, a combination of third- (PacBio) and second-generation (Illumina) sequencing technologies was applied to sequence full-length transcriptomes of okra. …”
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    Comparative physiological and full-length transcriptome analyses reveal the molecular mechanism of melatonin-mediated salt tolerance in okra (Abelmoschus esculentus L.)
  16. 233316
    “…RESULTS: The most common indication for the use of a rapid exchange extension catheter was vascular tortuosity (37.8%), followed by heavy calcification (28.9%), long lesions (20.0%), proximal stent (6.7%), in-stent restenosis (5.2%), and coronary origin anomalies (1.5%). The following technologies failed in passing targeted lesions before delivering the rapid exchange catheter: Multiple predilatation technique (57%), buddy wire technique (33.4%), balloon anchoring technique (5.9%), and cutting balloon modification (3.7%). …”
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    Application of a rapid exchange extension catheter technique in type B2/C nonocclusive coronary intervention via a transradial approach
  17. 233317
    “…Particularly, web-based technologies could be an accessible way to increase motivation and volition for PA and maintain daily PA routines.…”
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    Online Artículo Texto
    Is Physical Activity Associated with Less Depression and Anxiety During the COVID-19 Pandemic? A Rapid Systematic Review
  18. 233318
    “…The complex genomic organization of NCF1 poses a difficulty for high-throughput genotyping techniques and variants in this gene should be carefully evaluated when using the next generation and Sanger sequencing technologies. The p.Arg90His variant is found at a variable allele frequency in different populations, and is higher in people of South East Asian ancestry. …”
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    Homozygous variant p. Arg90His in NCF1 is associated with early-onset Interferonopathy: a case report
  19. 233319
    “…Further studies of novel thrombus aspiration technologies are warranted to improve patient outcomes. …”
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    Micro-CT-Based Quantification of Extracted Thrombus Burden Characteristics and Association With Angiographic Outcomes in Patients With ST-Elevation Myocardial Infarction: The QUEST-STEMI Study
  20. 233320
    “…CONCLUSIONS: 3DP and CFD models based on image data can be used for in vitro surgical simulation. These emerging technologies are now changing traditional models of diagnosis and treatment, and the role of imaging data will no longer be limited to diagnosis but will contribute more to assisting surgeons in choosing treatment strategies.…”
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    Hemodynamic testing using three-dimensional printing and computational fluid dynamics preoperatively may provide more information in mitral repair than traditional image dataset
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