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3por Mohaddesi, Behzad, Dwivedi, Ravindra, Ashok, B. K., Aghera, Hetal, Acharya, Rabinarayan, Shukla, V. J.“…In therapeutically equivalent dose level, analgesic activity was observed only after 180 min while in TED ×2 treated group analgesia was observed at 30 min and lasted even up to 240 min. …”
Publicado 2013
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4“…Experiments were carried out at two-dose levels, that is, therapeutically equivalent dose (TED) and TED × 2. Animals were divided into three groups (six animals in each group), first group serving as a control group, second and third group labeled as test drug group. …”
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5por Berger, Marcel, Matlach, Juliane, Pitz, Susanne, Berres, Manfred, Axmacher, Franz, Kahaly, George J., Brockmann, Marc A., Müller-Eschner, Matthias“…The angle of the medial orbital wall was significantly smaller (p < 0.001) in patients with TED (− 2.3 ± 3.6°) compared to patients with TED + DON (1.0 ± 4.1°). …”
Publicado 2022
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6por Ugradar, Shoaib, Kang, Julia, Kossler, Andrea L., Zimmerman, Erin, Braun, Jenna, Harrison, Andrew R., Bose, Swaraj, Cockerham, Kimberly, Douglas, Raymond S.“…METHODS: In this retrospective review, consecutive patients with chronic stable TED (>2 years), who had received ≥3 infusions of teprotumumab were included. …”
Publicado 2021
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7por Douglas, Raymond S, Couch, Steven, Wester, Sara T, Fowler, Brian T, Liu, Catherine, Subramanian, Prem, Tang, Rosa, Nguyen, Quang T, Maamari, Robi N, Hsu, Kate, Karon, Michael, Stan, Marius“…Methods: Pts met all following criteria: ≥18 yrs, TED 2-10 yrs, inactive disease or >1 yr without progression in proptosis/diplopia/new symptoms, baseline (BL) CAS≤1, increased proptosis ≥3mm before TED or from normal, euthyroid/mildly hypo/hyperthyroid, no prior teprotumumab and no steroids within 3 wks of screen. …”
Publicado 2023
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8por Chng, Chiaw-Ling, Seah, Lay Leng, Yang, Morgan, Shen, Sunny Yu, Koh, Siew Kwan, Gao, Yan, Deng, Lu, Tong, Louis, Beuerman, Roger Wilmer, Zhou, Lei“…For verification of results from discovery phase, sequential window acquisition of all theoretical fragment ion spectra (SWATH) was used to analyze an independent cohort from normal controls, AITD, mild TED and severe TED. Two proteins, S100A4 and PIP showed consistent dysregulation trends in the discovery and validation phase experiments. …”
Publicado 2018
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