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561por Haslbauer, Jasmin D., Zinner, Carl, Stalder, Anna K., Schneeberger, Jan, Menter, Thomas, Bassetti, Stefano, Mertz, Kirsten D., Went, Philip, Matter, Matthias S., Tzankov, Alexandar“…Microvascular dysfunction, evidenced by an upregulation of hemostatic (CD36, PROCR, VWF) and proangiogenic (FLT1, TEK) genes and an increase of fibrin microthrombi and CD105+ microvessels. …”
Publicado 2021
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562por Wang, Bin, Liu, Lixiao, Wu, Jinting, Mao, Xiaolu, Fang, Zhen, Chen, Yingyu, Li, Wenfeng“…Overall, 30 hypoxia- and immune-related genes were identified, and five hypoxia- and immune-related genes (EPO, PLAUR, TEK, TGFA, TGFB1) were ultimately selected. Survival analysis showed that the high-risk score on the hypoxia- and immune-related gene signature was significantly associated with adverse survival outcomes. …”
Publicado 2022
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563por Gilly, Arthur, Klaric, Lucija, Park, Young-Chan, Png, Grace, Barysenka, Andrei, Marsh, Joseph A., Tsafantakis, Emmanouil, Karaleftheri, Maria, Dedoussis, George, Wilson, James F., Zeggini, Eleftheria“…These were split between four cis signals for MARCO, TEK, MMP2 and MPO, and one trans association for GDF2 in the SERPINA11 gene. …”
Publicado 2022
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564por Ma, Yanyun, Wang, Chunxia, Shi, Mengqi, Li, Mingshan, Li, Lin, Che, Tuanjie, Qu, Jing“…Among these, six CpG sites in the CHRM2, LAMA4, COL11A1, FGF10, IGF1 and TEK genes were highly associated with HPV-16-positive cervical cancer, as validated using pyrophosphate sequencing. …”
Publicado 2022
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565por Khan, Hafiz Azhar Ali“…Khan, Lodhran, Bahawalpur, Toba Tek Singh, Bahawalnagar, Rajanpur and Jhang strains exhibited very high levels of resistance (RR > 100) to methomyl; Bhakkar, Kasur, Vehari, Layyah, Muzaffargarh and R.Y. …”
Publicado 2023
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566por Kim, Hyun-Jin, Son, Ho-young, Park, Philiip, Yun, Jae Moon, Kwon, Hyuktae, Cho, Belong, Kim, Jong-Il, Park, Jin-Ho“…We also identified several genetic susceptibility loci (e.g., CHST11, TEK, and ITGA1) implicated in candidate mechanisms such as inflammation and oxidative stress in the discovery step, although their interaction effects were not replicated. …”
Publicado 2023
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567por Fernandez-Aranda, F., Baenas, I., Etxandi, M., Mora-Maltas, B., Granero, R., Tovar, S., Diéguez, C., Potenza, M. N., Jiménez-Murcia, S.“…Potenza Grant / Research support from: Mohegan Sun Casino and Connecticut Council on Problem Gambling, Consultant of: Opiant Pharmaceuticals, Idorsia Pharmaceuticals, Baria-Tek, AXA, Game Day Data and the Addiction Policy Forum; has participated in surveys, mailings or telephone consultations related to drug addiction, impulse control disorders or other health topics; and has consulted for law offices and gambling entities on issues related to impulse control or addictive disorders, Employee of: patent application in Yale University and Novartis, S. …”
Publicado 2023
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568por Wu, Xin, Li, Fenghua, Xie, Wenjie, Gong, Binbin, Fu, Bin, Chen, Weimin, Zhou, Libo, Luo, Lianmin“…RESULTS: A prognostic 9-gene signature with ABCB1, AGER, E2F1, FOXM1, HADH, ISG15, KCNMA1, PLG, and TEK. The patients in the high risk group had apparently poor survival (TCGA: p < 0.001; E-MTAB-1980: p < 0.001). …”
Publicado 2023
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569por Velayudhan, Silpa Mullakkalparambil, Alam, Shahin, Yin, Tong, Brügemann, Kerstin, Buerkert, Andreas, Sejian, Veerasamy, Bhatta, Raghavendra, Schlecht, Eva, König, Sven“…The lead contaminated group revealed sweeps which were annotated with genes involved in carcass traits (TNNC2, SLC12A5, and GABRA4), milk yield (HTR1D, SLCO3A1, TEK, and OPCML), reproduction (GABRA4), hypoxia/stress response (OPRD1 and KDR), cell adhesion (PCDHGC3), inflammatory response (ADORA2A), and immune defense mechanism (ALCAM). …”
Publicado 2023
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570por Dai, Erbin, Liu, Li-Ying, Wang, Hao, McIvor, Dana, Sun, Yun ming, Macaulay, Colin, King, Elaine, Munuswamy-Ramanujam, Ganesh, Bartee, Mee Yong, Williams, Jennifer, Davids, Jennifer, Charo, Israel, McFadden, Grant, Esko, Jeffrey D., Lucas, Alexandra R.“…Inflammatory cell invasion and neointimal hyperplasia were significantly reduced in N-deacetylase-N-sulfotransferase-1 (Ndst1 (f/f) TekCre (+)) heparan sulfate (GAG)-deficient (Ndst1(−/−), p<0.044) and CCR2-deficient (Ccr2(−/−), p<0.04) donor transplants. …”
Publicado 2010
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571por Holopainen, Tanja, Saharinen, Pipsa, D’Amico, Gabriela, Lampinen, Anita, Eklund, Lauri, Sormunen, Raija, Anisimov, Andrey, Zarkada, Georgia, Lohela, Marja, Heloterä, Hanna, Tammela, Tuomas, Benjamin, Laura E., Ylä-Herttuala, Seppo, Leow, Ching Ching, Koh, Gou Young, Alitalo, Kari“…BACKGROUND: Angiopoietin-2 (Ang2), a ligand for endothelial TEK (Tie2) tyrosine kinase receptor, is induced in hypoxic endothelial cells of tumors, where it promotes tumor angiogenesis and growth. …”
Publicado 2012
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572por Gibby, Krissa, You, Weon-Kyoo, Kadoya, Kuniko, Helgadottir, Hildur, Young, Lawrence JT, Ellies, Lesley G, Chang, Yunchao, Cardiff, Robert D, Stallcup, William B“…NG2 ablation also diminishes the number of tumor-associated and TEK tyrosine kinase endothelial (Tie2) expressing macrophages in mammary tumors, providing another possible mechanism for reducing tumor vascularization and growth. …”
Publicado 2012
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573por Yan, S. Betty, Peek, Victoria L., Ajamie, Rose, Buchanan, Sean G., Graff, Jeremy R., Heidler, Steven A., Hui, Yu-Hua, Huss, Karen L., Konicek, Bruce W., Manro, Jason R., Shih, Chuan, Stewart, Julie A., Stewart, Trent R., Stout, Stephanie L., Uhlik, Mark T., Um, Suzane L., Wang, Yong, Wu, Wenjuan, Yan, Lei, Yang, Wei J., Zhong, Boyu, Walgren, Richard A.“…In subsequent nonclinical characterization, LY2801653 was found to have potent activity against several other receptor tyrosine oncokinases including MST1R, FLT3, AXL, MERTK, TEK, ROS1, DDR1/2 and against the serine/threonine kinases MKNK1/2. …”
Publicado 2012
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574por Badana, Anil, Chintala, Madhuri, Varikuti, Gayathri, Pudi, Nagaseshu, Kumari, Seema, Kappala, Vijaya Rachel, Malla, Rama Rao“…This study also demonstrated that MβCD treatment caused a respective 2.6- and 2.5-fold depletion of tyrosine protein kinase receptor (TEK) receptor tyrosine kinase levels in both TNBC cell lines. …”
Publicado 2016
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575por Chen, Hao, Ambadapadi, Sriram, Wakefield, Dara, Bartee, Meeyong, Yaron, Jordan R., Zhang, Liqiang, Archer-Hartmann, Stephanie A., Azadi, Parastoo, Burgin, Michelle, Borges, Chad, Zheng, Donghang, Ergle, Kevin, Muppala, Vishnu, Morshed, Sufi, Rand, Kenneth, Clapp, William, Proudfoot, Amanda, Lucas, Alexandra“…In prior work, conditional deficiency of the glycocalyx-modifying enzyme N-deacetylase-N-sulfotransferase-1 (Ndst1(f/f) TekCre(+)) reduced aortic allograft inflammation. …”
Publicado 2018
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576“…This study compared the performance of VisionTek digital microscope (VDM) (Sakura, Japan) and Hamamatsu NanoZoomer C9600-12 single Z-stack digital scan (SZDS) to conventional light microscopy (CLM) for FNA-ROSE. …”
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577por Saik, Olga V., Nimaev, Vadim V., Usmonov, Dilovarkhuja B., Demenkov, Pavel S., Ivanisenko, Timofey V., Lavrik, Inna N., Ivanisenko, Vladimir A.“…In particular, among genes involved in endothelial apoptosis, KDR, TNF, TEK, BMPR2, SERPINE1, IL10, CD40LG, CCL2, FASLG and ABL1 had the highest priority. …”
Publicado 2019
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578por Tsioutsiou, Efthymia Eleni, Giordani, Paolo, Hanlidou, Effie, Biagi, Marco, De Feo, Vincenzo, Cornara, Laura“…Several differences in Traditional Ethnobotanical Knowledge (TEK) were observed in relation to social and cultural components of the population. …”
Publicado 2019
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579por Söderholm, Martin, Pedersen, Annie, Lorentzen, Erik, Stanne, Tara M., Bevan, Steve, Olsson, Maja, Cole, John W., Fernandez-Cadenas, Israel, Hankey, Graeme J., Jimenez-Conde, Jordi, Jood, Katarina, Lee, Jin-Moo, Lemmens, Robin, Levi, Christopher, Mitchell, Braxton D., Norrving, Bo, Rannikmäe, Kristiina, Rost, Natalia S., Rosand, Jonathan, Rothwell, Peter M., Scott, Rodney, Strbian, Daniel, Sturm, Jonathan W., Sudlow, Cathie, Traylor, Matthew, Thijs, Vincent, Tatlisumak, Turgut, Woo, Daniel, Worrall, Bradford B., Maguire, Jane M., Lindgren, Arne, Jern, Christina“…Several variants detected in this study demonstrated suggestive association with outcome (p < 10(−5)), some of which are within or near genes with experimental evidence of influence on ischemic stroke volume and/or brain recovery (e.g., NTN4, TEK, and PTCH1). CONCLUSIONS: In this large GWA study on functional outcome after ischemic stroke, we report one significant variant and several variants with suggestive association to outcome 3 months after stroke onset with plausible mechanistic links to poststroke recovery. …”
Publicado 2019
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580por Vélez, Juan, Lange, Malin K., Zieger, Peter, Yoon, Ilkyu, Failing, Klaus, Bauer, Christian“…Calves within each block were allocated to one of 3 treatments: remaining untreated, fed with SCFP (Diamond V SmartCare(®) at 1 g/d in milk and NutriTek(®) at 5 g/d in starter grain) for the first 63 days of life, or treated with halofuginone (0.1 mg/kg/d) for the first 7 days of life. …”
Publicado 2019
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