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3121“…Administration of enzalutamide did not reduce testosterone levels, but helped maintain good quality of life, was more cost effective at low doses, and was previously shown to be heart healthy and efficacious during early stages of castration-resistant prostate cancer. Although we do not advocate enzalutamide as a treatment approach in these situations, we believe that a clinical trial to evaluate short-term low-dose treatment using enzalutamide is warranted.…”
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3122“…As La from Phoslock is bio-available to and taken up by the marbled crayfishes (Procambarus fallax f. virginalis), we advocate that the application of in-lake chemical water treatments to mitigate eutrophication should be accompanied by a thorough study on potential side effects.…”
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3123por André, Aurore, Quillévéré, Frédéric, Morard, Raphaël, Ujiié, Yurika, Escarguel, Gilles, de Vargas, Colomban, de Garidel-Thoron, Thibault, Douady, Christophe J.“…Results of these complementary approaches are highly congruent and lead to a molecular taxonomy that ranks 49 genetic types of planktonic foraminifera as genuine (pseudo)cryptic species. Our results advocate for a standardized sequencing procedure allowing homogenous delimitations of (pseudo)cryptic species. …”
Publicado 2014
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3124por Clark, Alex M., Bunin, Barry A., Litterman, Nadia K., Schürer, Stephan C., Visser, Ubbo“…By drastically reducing the time required for scientists to annotate their assays, we can realistically advocate for semantic annotation to become a standard part of the publication process. …”
Publicado 2014
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3125“…Accumulating evidence from anatomical, structural and functional imaging, and lesion studies advocate a cognitive network involving indirect connections between the cerebellum and non-motor areas in the prefrontal cortex. …”
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3126“…Surprisingly, we did not detect any megalin protein in adult terminal ileum and consistently, only extremely low amounts of LRP2 mRNA. Our data therefore advocate that cubilin and amnionless act independently of megalin in adult terminal ileum and that the cubilin‐megalin interdependency accordingly should be considered as tissue and ligand specific.…”
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3127por Lohiniva, Anna-Leena, Barakat, Amal, Dueger, Erica, Restrepo, Suzanne, El Aouad, Rajae“…Decision-making was strongly influenced by family, community, mass media, religious leaders and health providers suggesting that broad communication efforts should also be used to advocate for vaccination. Meaningful communication for future vaccine campaigns must consider these context-specific findings. …”
Publicado 2014
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3128por van der Gronde, Toon, Kempes, Maaike, van El, Carla, Rinne, Thomas, Pieters, Toine“…With better designed studies, more correlation between diverse fields, and more standardisation, it might be possible to elucidate underlying mechanisms. Thus, we advocate maintaining the current case-by-case differentiated approach to evidence-based forensic assessment.…”
Publicado 2014
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3129“…For metagenomic data, it has been observed that the variable coverage and presence of closely related organisms can lead to fragmented assemblies containing chimeric contigs that may reduce the accuracy of downstream analyses and some advocate the use of alternate data reduction techniques. …”
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3130por Gaskell, Katherine M., Rothe, Camilla, Gnanadurai, Roshina, Goodson, Patrick, Jassi, Chikondi, Heyderman, Robert S., Allain, Theresa J., Harrison, Thomas S., Lalloo, David G., Sloan, Derek J., Feasey, Nicholas A.“…National guidelines in Malawi and other African countries now advocate an increased induction dose of 1200mg. We assessed whether this has improved outcomes. …”
Publicado 2014
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3131por Mackey, Tim K, Werb, Daniel, Beletsky, Leo, Rangel, Gudelia, Arredondo, Jaime, Strathdee, Steffanie A“…We argue that Mexico’s reform is consistent with flexibilities allowed under international drug treaty instruments and related commentaries. We also advocate that drug policy reforms and future governance efforts should be based on empirical evidence, emphasize harm reduction practices, and integrate evidence-based evaluation and implementation of drug reform measures.…”
Publicado 2014
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3132por Zhang, Xiulan, Bloom, Gerald, Xu, Xiaoxin, Chen, Lin, Liang, Xiaoyun, Wolcott, Sara J“…Further, it documents how the Ministry of Health viewed its role as both an advocate for the interests of health facilities and health workers and as the agency responsible for ensuring that government health system objectives were met. …”
Publicado 2014
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3133“…A dosage calculation of 3 prism diopters/mm was established. CONCLUSIONS: We advocate a tailored surgical approach in FMNS with infantile unilateral visual loss. …”
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3134“…Wound dehiscence is reduced because this stitch type is stronger and exerts less tension on the tissue than the mattress stitch. We advocate the use of this novel stitch wherever a high-strength, low-tension repair is required. …”
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3135por Specker, Jona, Focquaert, Farah, Raus, Kasper, Sterckx, Sigrid, Schermer, Maartje“…SUMMARY: Based on our discussion of the arguments used in the debate on moral enhancement, and our assessment of this debate, we advocate a shift in focus. Instead of speculating about non-realistic hypothetical scenarios such as the genetic engineering of morality, or morally enhancing ‘the whole of humanity’, we call for a more focused debate on realistic options of biomedical treatment of moral pathologies and the concrete moral questions these treatments raise.…”
Publicado 2014
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3136“…Patients can be directed to HS support groups, where they can openly discuss their frustrations, share their experiences in dealing with HS, and band together to advocate for themselves. HS is misunderstood by both patients and physicians, often resulting in a delay in clinical presentation and diagnosis. …”
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3137por AlYami, Marja A., AlAhmari, Mohammed D., Alotaibi, Hajed, AlRabeeah, Saad, AlBalawi, Ibrahim, Mubasher, Mohamed“…Observations from various cohort studies, observational studies, and previously published literature advocate on the efficacy of NIV for treating non-COPD and non-traumatic AHRF patients. …”
Publicado 2015
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3138“…Objective: Numerous reports advocate that training of the proprioceptive sense is a viable behavioral therapy for improving impaired motor function. …”
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3139“…We recommend clutch volume as a sensitive, fine-grained measure of reproductive effort for research at a wide range of scales and advocate further analysis of ecological correlates of clutch volume in birds and amniotes generally.…”
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3140“…Rheumatoid arthritis comes with a 30% higher probability for cardiovascular disease than the general population. Current guidelines advocate for early and aggressive primary prevention and treatment of risk factors in high-risk populations but this excess risk is under-addressed in RA in real life. …”
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