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  1. 259901
    por Kopp, Matthias V., Muche-Borowski, Cathleen, Abou-Dakn, Michael, Ahrens, Birgit, Beyer, Kirsten, Blümchen, Katharina, Bubel, Petra, Chaker, Adam, Cremer, Monika, Ensenauer, Regina, Gerstlauer, Michael, Gieler, Uwe, Hübner, Inga-Marie, Horak, Fritz, Klimek, Ludger, Koletzko, Berthold V., Koletzko, Sybille, Lau, Susanne, Lob-Corzilius, Thomas, Nemat, Katja, Peters, Eva M.J., Pizzulli, Antonio, Reese, Imke, Rolinck-Werninghaus, Claudia, Rouw, Elien, Schaub, Bianca, Schmidt, Sebastian, Steiß, Jens-Oliver, Striegel, Anne Kathrin, Szépfalusi, Zsolt, Schlembach, Dietmar, Spindler, Thomas, Taube, Christian, Trendelenburg, Valérie, Treudler, Regina, Umpfenbach, Ulrich, Vogelberg, Christian, Wagenmann, Martin, Weißenborn, Anke, Werfel, Thomas, Worm, Margitta, Sitter, Helmut, Hamelmann, Eckard
    Publicado 2022
    “…This aspect is also reflected in the recommendations on animal husbandry, on which a differentiated statement was made: In families without a recognizable increased allergy risk, pet keeping with cats or dogs should not generally be restricted. …”
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    S3 Guideline Allergy Prevention*
  2. 259902
    “…CONCLUSIONS: The study demonstrates the potential for SS-31 to treat mitochondrial dysfunction in tendinopathy and to aid in tendon healing, based on both in vivo (animal model) and in vitro (human tenocytes) experiments. …”
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    Poster 100: Evaluation of SS-31 as a Potential Therapeutic in the Treatment of Tendinopathy
  3. 259903
    “…METHODS: All procedures were approved by our Institutional Animal Care and Use Committee. A total of 90 12-week-old male C57BL/6J mice were placed into 6 different groups (15 mice per group) (Fig 1A). …”
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    Poster 101: Evaluation of Novel Treatment Agents on Rotator Cuff Tendon and Muscle Pathology in a Murine Subacromial Impingement Model
  4. 259904
    por Tetlow, Lynne C, Woolley, David E
    Publicado 1999
    “…INTRODUCTION: 1α,25-dihydroxyvitamin D(3) [1α,25(OH)(2)D(3)], the biologically active metabolite of vitamin D(3), acts through an intracellular vitamin D receptor (VDR) and has several immunostimulatory effects. Animal studies have shown that production of some matrix metalloproteinases (MMPs) may be upregulated in rat chondrocytes by administration of 1α,25(OH)(2)D(3); and cell cultures have suggested that 1α,25(OH)(2)D(3) may affect chondrocytic function. …”
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    The effects of 1α,25-dihydroxyvitamin D(3) on matrix metalloproteinase and prostaglandin E(2) production by cells of the rheumatoid lesion
  5. 259905
    por Murray, Henry A.
    Publicado 1925
    “…The two processes, anabolism and catabolism, occur together and undoubtedly have some relationship, but surely one is not a measure of the other. In a starving animal, and so probably in a starving embryo, there is a considerable amount of so called basal metabolism. …”
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    PHYSIOLOGICAL ONTOGENY : A. CHICKEN EMBRYOS. II. CATABOLISM. CHEMICAL CHANGES IN FERTILE EGGS DURING INCUBATION. SELECTION OF STANDARD CONDITIONS.
  6. 259906
    por Kanwit Craig, Alexa
    Publicado 2018
    “…However, emerging evidence from animal models has shown rapid temperature changes following surgery may diminish or even negate the neuroprotective effect of intraoperative hypothermia. …”
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    2335: Delayed rewarming for neuroprotection in infants following congenital heart surgery: A safety study
  7. 259907
    “…This study could lead to clinical translation by moving into larger animal studies and eventually clinical trials. The success of this study was determined by analyzing the results of echocardiography data on cardiac function (ejection fraction, fractional shortening, and left ventricle inner diameter) and assessment of histological staining on cardiac tissue (fibrotic tissue formation, infarct size, wall thinning, blood vessel cell counts, and vessel size quantification) after MI. …”
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    3395 An Injectable Sulfonated Reversible Thermal Gel for Controlled and Localized Delivery of Vascular Endothelial Growth Factor to Promote Cardiac Protection After a Myocardial Infarction
  8. 259908
    “…Evidence favoring the use of adjunctive clindamycin in iBHS is predominantly from in vitro and animal studies. Clinical studies, limited to single-center series or active surveillance, have yielded mixed results. …”
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    473. Impact of Adjunctive Clindamycin in Invasive β-Hemolytic Streptococcal Infections: A Propensity Score-matched Analysis of 1956 β-lactam Treated Patients from 118 US Hospitals
  9. 259909
    “…Co-designed with parents and based on decades of parenting research, Parent Positive consists of three elements: (i) Parenting Boosters: where advice, delivered in the form of narrated animations, videos, graphics and text is provided to help parents with eight common parenting challenges; (ii) Parenting Exchange: a facilitated parent-to-parent communication and peer support platform and; (iii) Parent Resources: giving access to carefully selected high-quality, evidence-based online parenting resources. …”
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    Supporting Parents & Kids Through Lockdown Experiences (SPARKLE): A digital parenting support app implemented in an ongoing general population cohort study during the COVID-19 pandemic: A structured summary of a study protocol for a randomised controlled trial
  10. 259910
    “…These recent findings have resulted in a renewed interest in the ACL repair (ACL-r) procedure as a potentially more joint “friendly” secondary to less surgical trauma with the preservation of the native ACL ligament. In several animal models and in human clinical data, ACL remnant preservation and ACL entire ligament repair/preservation has been shown to benefit lower extremity and knee biomechanics, proprioception, and short term clinical outcomes. …”
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    Paper 84: Differences in Metrics of Knee Joint Loading Between Individuals Following a Primary Anterior Cruciate Ligament Repair (ACL-R) Surgery Versus Those Who Underwent a Standard ACL Reconstruction with a Patella Bone-Tendon-Bone Autograft (ACLR)
  11. 259911
    “…Sixty-four skeletally mature New Zealand White rabbits at seven months old were used in this study. Animal procedure: Before surgery, bone marrow aspirate was collected through the iliac crests in each rabbit under anesthesia and processed via a two-step centrifugation method to prepare BMAC. …”
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    Paper 40: Improved Cartilage Healing with Microfracture Augmented with Fisetin & Bone Marrow Aspirate Concentrate in Acute Osteochondral Defect
  12. 259912
    “…METHODS: All procedures were approved by our Institutional Animal Care and Use Committee (Protocol# 2019-0021). …”
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    Poster 130: Tendon-to-bone Healing in a CCR2 Knockout Mouse Model of Delayed Rotator Cuff Repair
  13. 259913
    por Marie, Ditte, Saunte, Lindhardt
    Publicado 2022
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    S6.2b In vitro susceptibility testing of dermatophytes: toward standardization
  14. 259914
    “…BACKGROUND: The gel-forming O-glycoprotein Mucin-2 (MUC2) is a key mediator of host-microbe homeostasis in part by forming a barrier to segregate inflammatory microbes from distal colon tissues. While animal models have provided insights into how Muc2 functions, relatively few studies have explored human MUC2. …”
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    A70 FECAL-ADHERENT MUCUS IS A NON-INVASIVE SOURCE OF PRIMARY HUMAN MUC2 FOR STRUCTURAL AND FUNCTIONAL CHARACTERIZATION IN HEALTH AND DISEASE
  15. 259915
    “…It is a challenge to isolate and characterize the effective components of centipedes due to limited peptide purification technologies for animal-derived medicines. AIM: To purify, characterize, and synthesize the bioactive components with the strongest antihepatoma activity from centipedes and determine the antihepatoma mechanism. …”
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    Antihepatoma peptide, scolopentide, derived from the centipede scolopendra subspinipes mutilans
  16. 259916
    por Hayman, J. M., Starr, Isaac
    Publicado 1925
    “…The blood pressure curve of this animal showed rhythmically occurring waves of the Traube-Hering type and dyspnea was noted. …”
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    EXPERIMENTS ON THE GLOMERULAR DISTRIBUTION OF BLOOD IN THE MAMMALIAN KIDNEY
  17. 259917
    “…As biopsy is the only way to obtain first-trimester decidua from pregnant women living with HIV on PI-cART, ethics approval and participant consent are difficult to obtain. Furthermore, our animal model is limited to the study of cART and does not include HIV. …”
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    Periconceptional exposure to lopinavir, but not darunavir, impairs decidualization: a potential mechanism leading to poor birth outcomes in HIV-positive pregnancies
  18. 259918
    “…CONCLUSIONS: The GnRH-a injection could achieve the desired effect. The animal model successfully achieved a significant decrease in the E2, FSH, and LH levels in rats, and could cause the rats to have rising body surface temperature similar to hot flashes in the perimenopausal period. …”
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    GnRH-a-Induced Perimenopausal Rat Modeling and Black Cohosh Preparations’ Effect on Rat’s Reproductive Endocrine
  19. 259919
    “…CONCLUSION: PTHrP acts through the Met pathway in CRC cells and regulates Met expression in a CRC animal model. More basic and clinical studies are needed to further evaluate the PTHrP/Met relationship.…”
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    Involvement of Met receptor pathway in aggressive behavior of colorectal cancer cells induced by parathyroid hormone-related peptide
  20. 259920
    por Lukas, W., Remi, C.
    Publicado 2023
    “…En effet, dans un modèle animal ex vivo, il est observé lors de l’inflation pulmonaire avec un gaz et non avec un liquide. …”
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    The Avalanche Study
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