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1548441“…CONCLUSIONS: Exebacase used in addition to SoC was associated with a reduction in length of hospital stay and 30-day readmission rates for all causes and for S. aureus compared with SoC alone in patients being treated for MRSA bacteremia/endocarditis. …”
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1548442por Rebeiro, Peter F, Rebeiro, Peter F, Jenkins, Cathy, Bian, Aihua, Lake, Jordan, Lake, Jordan, Bourgi, Kassem, Bourgi, Kassem, Horberg, Michael A, Horberg, Michael A, Moore, Richard, Moore, Richard, Altoff, Keri, Klein, Marina, Eron, Joseph J, Eron, Joseph J, Gill, M John, Kitahata, Mari, Napravnik, Sonia, Silverberg, Michael, Mayor, Angel M, Willig, Amanda, Willig, Amanda, Floris-Moore, Michelle, Sterling, Timothy, Koethe, John R, Koethe, John R“…NNRTI-based ART was associated with a 50% increased risk of DM (HR = 1.50, CI: 1.11–2.03). …”
Publicado 2019
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1548443por Garg, Shikha, O’Halloran, Alissa, O’Halloran, Alissa, Cummings, Charisse N, Cummings, Charisse N, Holstein, Rachel, Kniss, Krista, Anderson, Evan J, Anderson, Evan J, Bennett, Nancy M, Bennett, Nancy M, Billing, Laurie M, Billing, Laurie M, Herlihy, Rachel, Hill, Mary, Irizarry, Lourdes, Irizarry, Lourdes, Kim, Sue, Kim, Sue, Kirley, Pam D, Lynfield, Ruth, Lynfield, Ruth, Monroe, Maya, Monroe, Maya, Spina, Nancy, Talbot, Keipp, Talbot, Keipp, Thomas, Ann, Thomas, Ann, Yousey-Hindes, Kimberly, Budd, Alicia, Brammer, Lynette, Reed, Carrie, Reed, Carrie“…We multiply imputed influenza A subtype for 63% of cases with unknown subtype and based imputation on factors that could be associated with missing subtype including surveillance site, 10-year age groups and month of hospital admission. …”
Publicado 2019
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1548444por Shorr, Andrew F, Schranz, Jennifer, Goldberg, Lisa, Paukner, Susanne, Das, Anita F, Moran, Gregory J, Sandrock, Christian, File, Thomas M, Alexander, Elizabeth, Gelone, Steven P“…BACKGROUND: LP is associated with severe CABP, rapid onset, and high morbidity/mortality. …”
Publicado 2019
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1548445“…Reported prescription opioid misuse is common among adolescents and young adults and often associated with additional substance abuse, underscoring the importance of drug and alcohol screening programs in this population. …”
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1548446por Harris, Samantha, Dykxhoorn, Jennifer, Hollander, Anna-Clara, Dalman, Christina, Kirkbride, James B.“…Finally, while a PTSD diagnosis was over 5 times more common in refugees than the Swedish-born population, it was more strongly associated with increased rates of substance use disorders in the Swedish-born population (aHR: 7.36; 95% CI 6.79–7.96) than non-refugee migrants (HR: 4.88; 95% CI 3.71–6.41; likelihood ratio test [LRT]: p = 0.01). …”
Publicado 2019
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1548447por Neubert, Patrick, Weichselbaum, Andrea, Reitinger, Carmen, Schatz, Valentin, Schröder, Agnes, Ferdinand, John R., Simon, Michaela, Bär, Anna-Lorena, Brochhausen, Christoph, Gerlach, Roman G., Tomiuk, Stefan, Hammer, Karin, Wagner, Stefan, van Zandbergen, Ger, Binger, Katrina J., Müller, Dominik N., Kitada, Kento, Clatworthy, Menna R., Kurts, Christian, Titze, Jens, Abdullah, Zeinab, Jantsch, Jonathan“…Abbreviations: ACT: actins; AKT: AKT serine/threonine kinase 1; ATG2A: autophagy related 2A; ATG4C: autophagy related 4C, cysteine peptidase; ATG7: autophagy related 7; ATG12: autophagy related 12; BECN1: beclin 1; BMDM: bone marrow-derived macrophages; BNIP3: BCL2/adenovirus E1B interacting protein 3; CFU: colony forming units; CM-H(2)DCFDA: 5-(and-6)-chloromethyl-2′,7′-dichlorodihydrofluorescein diacetate, acetyl ester; CTSB: cathepsin B; CYBB: cytochrome b-245 beta chain; DAPI: 4,6-diamidino-2-phenylindole; DMOG: dimethyloxallyl glycine; DPI: diphenyleneiodonium chloride; E. coli: Escherichia coli; FDR: false discovery rate; GFP: green fluorescent protein; GSEA: gene set enrichment analysis; GO: gene ontology; HIF1A: hypoxia inducible factor 1, alpha subunit; HUGO: human genome organization; HS: high salt (+ 40 mM of NaCl to standard cell culture conditions); HSP90: heat shock 90 kDa proteins; LDH: lactate dehydrogenase; LPS: lipopolysaccharide; Lyz2/LysM: lysozyme 2; NFAT5/TonEBP: nuclear factor of activated T cells 5; MΦ: macrophages; MAP1LC3/LC3: microtubule associated protein 1 light chain 3; MFI: mean fluorescence intensity; MIC: minimum inhibitory concentration; MOI: multiplicity of infection; MTOR: mechanistic target of rapamycin kinase; NaCl: sodium chloride; NES: normalized enrichment score; n.s.: not significant; NO: nitric oxide; NOS2/iNOS: nitric oxide synthase 2, inducible; NS: normal salt; PCR: polymerase chain reaction; PGK1: phosphoglycerate kinase 1; PHOX: phagocyte oxidase; RFP: red fluorescent protein; RNA: ribonucleic acid; ROS: reactive oxygen species; sCFP3A: super cyan fluorescent protein 3A; SBFI: sodium-binding benzofuran isophthalate; SLC2A1/GLUT1: solute carrier family 2 (facilitated glucose transporter), member 1; SQSTM1/p62: sequestosome 1; ULK1: unc-51 like kinase 1; v-ATPase: vacuolar-type H(+)-ATPase; WT: wild type…”
Publicado 2019
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1548448por Livingston, Man J., Wang, Jinghong, Zhou, Jiliang, Wu, Guangyu, Ganley, Ian G., Hill, Joseph A., Yin, Xiao-Ming, Dong, Zheng“…Abbreviations: ACTB: actin, beta; ATG: autophagy related; BNIP3: BCL2 interacting protein 3; BNIP3L/NIX: BCL2 interacting protein 3 like; BUN: blood urea nitrogen; CASP3: caspase 3; CCCP: carbonyl cyanide 3-chlorophenylhydrazone; COX4I1: cytochrome c oxidase subunit 4I1; COX8: cytochrome c oxidase subunit 8; DAPI: 4ʹ,6-diamidino-2-phenylindole; DNM1L: dynamin 1 like; EGFP: enhanced green fluorescent protein; EM: electron microscopy; ER: endoplasmic reticulum; FC: floxed control; FIS1: fission, mitochondrial 1; FUNDC1: FUN14 domain containing 1; H-E: hematoxylin-eosin; HIF1A: hypoxia inducible factor 1 subunit alpha; HSPD1: heat shock protein family D (Hsp60) member 1; IMMT/MIC60: inner membrane mitochondrial protein; IPC: ischemic preconditioning; I-R: ischemia-reperfusion; IRI: ischemia-reperfusion injury; JC-1: 5,5ʹ,6,6ʹ-tetrachloro-1,1ʹ,3,3ʹ-tetraethylbenzimidazolylcarbocyanine iodide; KO: knockout; MAP1LC3B/LC3B: microtubule associated protein 1 light chain 3 beta; mito-QC: mito-quality control; mRFP: monomeric red fluorescent protein; NAC: N-acetylcysteine; PINK1: PTEN induced putative kinase 1; PPIB: peptidylprolyl isomerase B; PRKN: parkin RBR E3 ubiquitin protein ligase; ROS: reactive oxygen species; RPTC: rat proximal tubular cells; SD: standard deviation; sIPC: simulated IPC; SQSTM1/p62: sequestosome 1; TOMM20: translocase of outer mitochondrial membrane 20; TUNEL: terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling…”
Publicado 2019
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1548449por Yuan, Hui, Wang, Yong, Liu, Peng-Fei, Yue, Yun-Long, Guo, Jin-Song, Wang, Zhen-ChangEnlace del recurso
Publicado 2019
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1548450“…CONCLUSION: OJ-induced liver injury and hepatocyte apoptosis are associated with the activation of the PERK-CHOP-GADD34 pathway and increased Bax/Bcl-2 ratio. …”
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1548451Range Variability in CMR Feature Tracking Multilayer Strain across Different Stages of Heart Failurepor Tanacli, Radu, Hashemi, Djawid, Lapinskas, Tomas, Edelmann, Frank, Gebker, Rolf, Pedrizzetti, Gianni, Schuster, Andreas, Nagel, Eike, Pieske, Burkert, Düngen, Hans-Dirk, Kelle, Sebastian“…Heart failure (HF) is associated with progressive ventricular remodeling and impaired contraction that affects distinctly various regions of the myocardium. …”
Publicado 2019
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1548452“…PURPOSE: (1) To define the characteristics of pitchers drafted after UCLR associated with placement in AAA and MLB professional levels and completion of a career of at least 3 years, (2) to define characteristics placing pitchers at risk for reinjury after surgery, (3) to compare the professional-level placement and career duration of the UCLR cohort with a matched control group, and (4) to evaluate the accuracy of team physician predraft risk assessments to predict elbow reinjury in pitchers with a history of UCLR. …”
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1548453por Howard, Robert, Zubko, Olga, Bradley, Rosie, Harper, Emma, Pank, Lynn, O’Brien, John, Fox, Chris, Tabet, Naji, Livingston, Gill, Bentham, Peter, McShane, Rupert, Burns, Alistair, Ritchie, Craig, Reeves, Suzanne, Lovestone, Simon, Ballard, Clive, Noble, Wendy, Nilforooshan, Ramin, Wilcock, Gordon, Gray, RichardEnlace del recurso
Publicado 2019
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1548454por Din, U.S.U., Brook, M.S., Selby, A., Quinlan, J., Boereboom, C., Abdullah, H., Franchi, M., Narici, M.V., Phillips, B.E., Williams, J.W., Rathmacher, J.A., Wilkinson, D.J., Atherton, P.J., Smith, K.“…Age-related sarcopenia and dynapenia are associated with frailty and metabolic diseases. Resistance exercise training (RET) adjuvant to evidence-based nutritional intervention(s) have been shown as mitigating strategies. …”
Publicado 2019
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1548455por Williamson, Heidi, Hamlet, Claire, White, Paul, Marques, Elsa M R, Paling, Thomas, Cadogan, Julia, Perera, Rohan, Rumsey, Nichola, Hayward, Leighton, Harcourt, Diana“…OBJECTIVE: To establish the feasibility of evaluating YPF for 12-17 year olds self-reporting appearance-related distress and/or bullying associated with a visible difference. METHODS: Randomized controlled trial with nested qualitative and economic study evaluating YPF compared with usual care (UC). …”
Publicado 2019
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1548456por Mayer, Gwendolyn, Gronewold, Nadine, Alvarez, Simone, Bruns, Bastian, Hilbel, Thomas, Schultz, Jobst-Hendrik“…When asked about potential risks, all groups reported slight concerns regarding data security (mean 0.85, SD 1.09; 95% CI 0.72-0.98). Patient age was associated with several attitudes toward e-mental health apps (future expectations: r=–0.31, P=.005; total risk score: r=0.22, P=.05). …”
Publicado 2019
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1548457por Garcia, M. Kay, Meng, Zhiqiang, Rosenthal, David I., Shen, Yehua, Chambers, Mark, Yang, Peiying, Wei, Qi, Hu, Chaosu, Wu, Caijun, Bei, Wenying, Prinsloo, Sarah, Chiang, Joseph, Lopez, Gabriel, Cohen, LorenzoEnlace del recurso
Publicado 2019
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1548458por Gharahdaghi, Nima, Rudrappa, Supreeth, Brook, Matthew S., Idris, Iskandar, Crossland, Hannah, Hamrock, Claire, Abdul Aziz, Muhammad Hariz, Kadi, Fawzi, Tarum, Janelle, Greenhaff, Paul L., Constantin‐Teodosiu, Dumitru, Cegielski, Jessica, Phillips, Bethan E., Wilkinson, Daniel J., Szewczyk, Nathaniel J., Smith, Kenneth, Atherton, Philip J.“…BACKGROUND: The andropause is associated with declines in serum testosterone (T), loss of muscle mass (sarcopenia), and frailty. …”
Publicado 2019
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1548459por Shen, Qi‐jie, Zhang, Jin‐li, Xing, Guo‐sheng, Liu, Zhong‐yu, Li, En‐qi, Zhao, Bao‐cheng, Zheng, Yu‐chen, Cao, Qing, Zhang, TaoEnlace del recurso
Publicado 2019
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1548460por Violette, Lauren R, Niemann, Lisa A, McMahan, Vanessa M, Katz, David A, Chavez, Pollyanna R, Clark, Hollie A, Cornelius-Hudson, Andy, Ethridge, Steven F, McDougal, Sarah J, Ure II, George, Stekler, Joanne D, Delaney, Kevin P“…OBJECTIVE: The objective of this study was to develop survey questions addressing aggregate and partner-specific group sex behaviors to measure prevalence of GSEs and associated risks in persons participating in Project Diagnostic Evaluation To Expand Critical Testing Technologies (DETECT), including MSM seeking HIV and STD testing at a public clinic in Seattle, Washington. …”
Publicado 2019
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