“…The different TDP-43 patterns were associated with clinically typical AD symptoms in 80% of AD(TDP + CTF) cases, 63,6% of AD(TDP + FL) and 100% of the AD(TDP-) cases. …”
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“…BACKGROUND: Socioeconomic disadvantage is associated with a reduced likelihood of smoking cessation. …”
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“…The ligand-independent pS134-GR transcriptome encompasses TGFβ1 and MAPK signaling gene sets associated with TNBC cell survival and migration/invasion. …”
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“…Among performance-enhancing substances, the most common and known substances are anabolic-androgenic steroids, which are associated with a range of short and long-term adverse medical and psychiatric effects. …”
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“…Significantly, cyanosis (OR[95%CI]: 3.13[1.51–6.51], p = 0.002), jaundice (OR[95%CI]: 2.10[1.07–4.14], p = 0.031), number of invasive devices (OR[95%CI]: 2.52[1.08–5.85], p = 0.031) and contaminated cot (OR[95%CI]: 2.39[1.26–4.55], p = 0.008) were associated with bacteremia due to GNB. Use of tap water only (OR[95%CI]: 2.12[0.88–5.09], p = 0.040) was protective for bacteremia due to GNB. …”
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“…In the adjusted multinomial logistic regression model, men’s age categories 25–34 years (AOR:2.0; 95%CI = 1.5–2.5), 35–44 (AOR: 2.8; 95%CI = (2.0–3.8), and 45(+) years (AOR: 1.5; 95%CI = 1.0–2.6), being rural resident (AOR: 1.60; (95%CI = 1.3–2.2), married and living with partner (AOR: 0.03; (95%CI = 0.01–0.06), who attended secondary (AOR:1.2; (95%CI = 0.8–1.9) and higher (AOR: 1.4; (95%CI = 1.2–2.5) education, whose partner was working (AOR: 1.6; (95%CI = 1.3–2.2), having three and above children (AOR: 0.5; (95%CI = 0.3–0.8), reading newspaper/magazines at least once a week or less than once a week, listening to radio at least once a week, watching television at least once a week and watching television less than once a week were significantly associated with use of male method than traditional/no method as compared to their respective references. …”
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“…Conclusions: Different types of loss-of-function MKRN3 mutations were associated with premature sexual development in both sexes. …”
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“…On the other hand, day 2 SHBG levels correlated positively with weight at 6 (r=0.311, p=0.04) and 24 months (r=0.353, p=0.02) of age. These associations remained significant after adjusting for gender, BW, gestational age, breastfeeding status and fruit juice intake at 6 months (R(2)=0.28, p=0.048) and for gender, BW, gestational age, breastfeeding status, sweet snack intake and screen viewing habits at 24 months (R(2)=0.33, p=0.046). …”
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“…We report a rare case of a post-menopausal woman with hirsutism associated with virilization due to Leydig cell tumors (LCT) of both ovaries. …”
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“…We also compared the AJCC staging systems with the American Thyroid Association (ATA) Risk Classification. Of 814 consecutive pts seen during this period, 94 were excluded either due to their diagnosis being medullary or anaplastic thyroid cancer (37) or because of deficient data. …”
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“…Each infusion comprised gadolinium contrast agent and ~3-4 x 10(10) adeno-associated virus 8 (AAV8) particles containing either a shRNA specific for ESR1 (n=6, ERaKD) or scrambled shRNA (n=5, control). …”
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“…Background: Obesity and type 2 diabetes mellitus (T2DM) are both associated with normal to above average bone mineral density (BMD) but increased risk of fragility fractures. …”
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“…Although the prevalence of diabetes, hepatic steatosis and other co-morbidities associated with metabolic control were similar in both groups at the time of the study, patients with RQ pathogenic variants were diagnosed later in life with diabetes (46.0 ± 4.2 years vs. 35 ± 3.5 years, p = 0.03) and hepatic steatosis (45.3 ± 6.9 years vs. 30.1 ± 3.7 years, p < 0.01. …”
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“…Regardless of their severity, VFx are associated with significant morbidity and carry the highest subsequent fracture rate of any fragility fracture. …”
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“…Background: Hypogonadism and hypocortisolism are present in a sizeable proportion of chronic opioid users. (1) An association with hypothyroidism, however, has not been demonstrated. …”
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“…We show here for the first time that 6 months of metreleptin treatment in humans with LD decreased DNL by 84% and was associated with reductions in glycemia and improved peripheral and hepatic insulin sensitivity. …”
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“…BRAFV600E mutations are found in more than fifty percent of LCH cases and are associated with worse outcomes. This case demonstrates the successful use of targeted BRAF inhibitor therapy in an adult patient with BRAF mutated hypothalamic LCH.…”
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“…The presence of diabetes was associated with higher BPI-SS scores: 3.50 (1.50-5.00) vs. 0 (0-3.25), p = 0.030). …”
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“…Conclusion: Loading dose of cholecalciferol in patients with acromegaly is associated with less production of 3-epi-25(OH)D3, and results in lower inactive fraction of vitamin D than in healthy controls. …”
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“…His abnormal thyroid function tests may be secondary to TSH resistance associated with the GNAS gene mutation. He was told to continue the current dose of calcium carbonate but to discontinue ergocalciferol and cholecalciferol. …”
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