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1548821por Edlow, Andrea G., Li, Jonathan Z., Collier, Ai-ris Y., Atyeo, Caroline, James, Kaitlyn E., Boatin, Adeline A., Gray, Kathryn J., Bordt, Evan A., Shook, Lydia L., Yonker, Lael M., Fasano, Alessio, Diouf, Khady, Croul, Natalie, Devane, Samantha, Yockey, Laura J., Lima, Rosiane, Shui, Jessica, Matute, Juan D., Lerou, Paul H., Akinwunmi, Babatunde O., Schmidt, Aaron, Feldman, Jared, Hauser, Blake M., Caradonna, Timothy M., De la Flor, Denis, D’Avino, Paolo, Regan, James, Corry, Heather, Coxen, Kendyll, Fajnzylber, Jesse, Pepin, David, Seaman, Michael S., Barouch, Dan H., Walker, Bruce D., Yu, Xu G., Kaimal, Anjali J., Roberts, Drucilla J., Alter, GalitEnlace del recurso
Publicado 2020
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1548822por Lanini, Simone, Montaldo, Chiara, Nicastri, Emanuele, Vairo, Francesco, Agrati, Chiara, Petrosillo, Nicola, Scognamiglio, Paola, Antinori, Andrea, Puro, Vincenzo, Di Caro, Antonino, De Carli, Gabriella, Navarra, Assunta, Agresta, Alessandro, Cimaglia, Claudia, Palmieri, Fabrizio, D’Offizi, Gianpiero, Marchioni, Luisa, Kobinger, Gary Pignac, Maeurer, Markus, Girardi, Enrico, Capobianchi, Maria Rosaria, Zumla, Alimuddin, Locatelli, Franco, Ippolito, Giuseppe“…Age (OR = 2.59; 95%CI 1.04–6.45; p = 0.042), obesity (OR = 5.13; 95%CI 1.81–14.50; p = 0.002), renal chronic failure (OR = 5.20; 95%CI 1.80–14.97; p = 0.002) and cardiovascular diseases (OR 2.79; 95%CI 1.29–6.03; p = 0.009) were independently associated with poor clinical outcome at 30 days after symptoms’ onset. …”
Publicado 2020
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1548823por Chan, Mark Y., Koh, Karen W. L., Poh, Sock-Cheng, Marchesseau, Stephanie, Singh, Devinder, Han, Yiying, Ng, Faclin, Lim, Eleanor, Prabath, Joseph F., Lee, Chi-Hang, Sim, Hui-Wen, Chen, Ruth, Carvalho, Leonardo, Tan, Sock-Hwee, Loh, Joshua P. Y., Tan, Jack W. C., Kuwelker, Karishma, Amanullah, R. M., Chin, Chee-Tang, Yip, James W. L., Lee, Choy-Yee, Gan, Juvena, Lo, Chew-Yong, Ho, Hee-Hwa, Hausenloy, Derek J., Tai, Bee-Choo, Richards, A. MarkEnlace del recurso
Publicado 2020
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1548824por Zhang, Junji, Zhao, Yuqian, Dai, Yi, Dang, Le, Ma, Li, Yang, Chunxia, Li, Yang, Kong, Linghua, Wei, Lihui, Zhang, Shulan, Liu, Jihong, Xi, Minrong, Chen, Long, Duan, Xianzhi, Xiao, Qing, Abulizi, Guzhalinuer, Zhang, Guonan, Hong, Ying, Gao, Xiaohong, Zhou, Qi, Xie, Xing, Li, Li, Niyazi, Mayinuer, Zhang, Zhifen, Tuo, Jiyu, Ding, Yiling, Si, Manfei, Chen, Fei, Song, Li, Qiao, Youlin, Lang, JingheEnlace del recurso
Publicado 2020
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1548825por Andrew, Melissa K, Kim, Joon Hyung, Matthews, Sean, Dessart, Christophe, levin, myron J, Oostvogels, Lidia, Riley, Megan, Schmader, Kenneth E, McNeil, Shelly, Schuind, Anne, Curran, Desmond“…Given that frailty is strongly associated with vulnerability to illness and adverse health outcomes, we studied how frailty impacts RZV VE, immunogenicity, reactogenicity, and safety. …”
Publicado 2020
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1548826por Biolchi, Alessia, Tomei, Sara, Santini, Laura, Gaetana, Rita La, Mori, Elena, Novy, Patricia, Rappuoli, Rino, Bekkat-Berkani, Rafik, Giuliani, Marzia Monica, Pizza, Mariagrazia, Sciences, Biological“…BACKGROUND: Meningococcal outbreaks have often been associated with N. meningitidis serogroup B (MenB) in high-income countries. …”
Publicado 2020
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1548827por Beaver, Ryan, Choi, Hosoon, Jinadatha, Chetan, Kaye, Keith S, Chatterjee, Piyali, Allton, Yonhui, Stibich, Mark, Kilgore, Paul E, Dhar, Sorabh“…BACKGROUND: Klebsiella pneumoniae is among the leading causes of healthcare-associated infections (HAI). Multidrug-resistant (MDR) Klebsiella variants are difficult to treat and have been reported with increasing frequency in hospitals. …”
Publicado 2020
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1548828por Muir, Lori A, Walpole, Susannah M, Warfel, Patricia A, Kwak, Hanna, Phelan, Anne-Marie, Moore, Gary E, Jain, Akash, Keutzer, Tim, Dane, Aaron, Dane, Aaron, Melnick, David, Talley, Angela K“…The most frequent TEAEs were diarrhea (5.0%) and headache (3.8%). No C. difficile-associated TEAEs were observed in the TBP-PI-HBr group; 3 cases occurred in the ertapenem group. …”
Publicado 2020
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1548829“…As increased carbapenem utilization is associated with the development of carbapenem resistance, antimicrobial stewardship has targeted non-carbapenem options. …”
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1548830por Dunn, Keith, Huang, Yangxin, Baugh, Bryan, Bejou, Nika, Luo, Donghan, Campbell, Jennifer, Anderson, David“…BACKGROUND: Ritonavir boosted protease inhibitors have been associated with GI intolerance. A post hoc analysis was conducted to assess the GI profile of D/C/F/TAF in treatment naïve patients. …”
Publicado 2020
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1548831por Collens, Sarah I, Wilcox, Douglas R, Mukerji, Shibani, Mateen, Farrah J, Solomon, Isaac H“…Of the patients who received IVIG, increased time from hospital admission to IVIG administration correlated with worse long-term disability as assessed by modified Rankin Score (mRS) (r=0.72, p=0.02); steroid use was not associated with mRS score. The mortality was 12%. Figure 1. …”
Publicado 2020
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1548832por Viehman, J Alex, Nguyen, M Hong, Garner, Will, Apostolopoulou, Anna, Harris, Gavin H, Lucas, Aaron, Jagadeesan, Vidya, Butler, Sharlay, Rapinski, Glen J, McCreary, Erin K, Arbulu, Ricardo, Ganchuk, Steven, Yang, Anne, Avasarala, Amitha, Trificante, Rosalie, Bollam, Rahul, Zou, Richard H, Moghbeli, Kaveh, Darwish, Malik, Hemadri, Amit, Weslander, Erin, Campfield, Brian T, Michaels, Marian G, Haidar, Ghady, Daley, Jesssica, Martin, Elise, Bariola, J Ryan“…Non-adherence to systemic guidelines was infrequent, and not associated with adverse outcomes. A COVID-19 treatment team of physicians and pharmacists can effectively coordinate therapy across hospitals in the setting of rapidly changing guidelines. …”
Publicado 2020
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1548833por Hsu, Yu-Lung, Chang, Shih-Ni, Kuo, Chin-Chi, Lin, Che-Chen, Lin, Hsiao-Chuan, Lai, Huan-Cheng, Hwang, Kao-Pin, Chiang, Hsiu-Yin“…Significant risk factors associated with GP-UTI in the multivariable analysis were: age >= 24 months [odds ratio (OR) 3.40, 95% confidence interval (CI) 1.40-8.26], serum white blood cell (WBC) (compared to ≥14.4 x 10(3)/μL) [OR 2.18, 95% CI 1.26-3.77], hemoglobin (compared to < 11.3 g/dL) [OR 1.89, 95% CI 1.04-3.45], negative urine leukocyte esterase [OR 3.12, 95% CI 1.83-5.33], negative urine nitrite [OR 4.14, 95% CI 1.88-9.14] and urine WBC (compared to ≥420/μL) [OR 2.16, 95% CI: 1.09, 4.26] (Table 1). …”
Publicado 2020
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1548834por Haddadin, Zaid, Rankin, Danielle A, Yanis, Ahmad, Shawareb, Yanal, Hamdan, Olla, Saada, Malek, Hilal, Sara, Alhajajra, Ahmad, Marar, Basima, Khuri-Bulos, Najwa“…BACKGROUND: Respiratory syncytial virus (RSV) is the leading cause of acute respiratory infections (ARI) hospitalizations in young children and is associated with increased severity compared to other viruses. …”
Publicado 2020
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1548835por Castanheira, Mariana, Woosley, Leah, Motyl, Mary, Han, Seongah, Campbell, Havilland“…BACKGROUND: Invasive aspergillosis (IA) is a life-threatening disease with limited treatment options and is associated with delays in effective treatment and significant early mortality. …”
Publicado 2020
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1548836por Gandhi, Rajesh, Cyktor, Joshua, Bosch, Ronald, Mar, Hanna, Laird, Gregory, Martin, Albine, Collier, Ann, Riddler, Sharon, Macatangay, Bernard, Rinaldo, Charles, Eron, Joseph J, Siliciano, Janet, McMahon, Deborah, Mellors, John“…At timepoint 1, intact provirus levels on ART correlated with total HIV-1 DNA and residual plasma viremia, but there was no evidence for associations between intact provirus levels and inflammation or immune activation. …”
Publicado 2020
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1548837por Rios, Patricia De Los, Allan, Brent, Okoli, Chinyere, Young, Benjamin, Castellanos, Erika, Brough, Garry, Eremin, Anton, Corbelli, Giulio Maria, Muchenje, Marvelous, Britton, Marta M C, Van de Velde, Nicolas“…Difficulty swallowing, any side effects, and privacy concerns were associated with increased odds of suboptimal overall health (AOR 2.10, 1.88, and 1.43, respectively) and suboptimal adherence (AOR 2.51, 1.50, and 1.87, respectively; all P< 0.05); results for other outcomes are in Figure 2. …”
Publicado 2020
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1548838por Tipping, Robert, Du, Jiejun, Losada, Maria C, Brown, Michelle L, Young, Katherine, Butterton, Joan R, Paschke, Amanda, Chen, Luke F“…BACKGROUND: In the RESTORE-IMI 2 trial, imipenem/cilastatin/relebactam (IMI/REL) was non-inferior to PIP/TAZ for treating hospital-acquired/ventilator-associated bacterial pneumonia (HABP/VABP) in the primary endpoint of Day 28 all-cause mortality (D28 ACM) and the key secondary endpoint of clinical response (CR) at early follow-up (EFU; 7-14 d after end of therapy). …”
Publicado 2020
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1548839por Holstein, Rachel, Dawood, Fatima S, Kirley, Pam Daily, Herlihy, Rachel, Yousey-Hindes, Kim, Fawcett, Emily, Monroe, Maya, Kim, Sue, Lynfield, Ruth, McMullen, Chelsea L, Muse, Alison, Billing, Laurie M, Sutton, Melissa, Talbot, Helen, Risk, Ilene, Garg, Shikha“…BACKGROUND: Pregnant women are at high-risk for influenza-associated hospitalization. We used data from the U.S. …”
Publicado 2020
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1548840por Hu, Tianyan, Sarpong, Eric, Song, Yan, Done, Nicolae, liu, Qing, Signorovitch, James, Petigara, Tanaz“…To demonstrate the potential value of V114, it is important to estimate the remaining burden associated with pneumococcal pneumonia (PP). This study was to estimate incidence rates (IRs) of non-invasive PP before and after PCV7 and PCV13 introduction in children in the US. …”
Publicado 2020
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