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1550581por Doyle, Aoife M, Bandason, Tsitsi, Dauya, Ethel, McHugh, Grace, Grundy, Chris, Dringus, Stefanie, Dziva Chikwari, Chido, Ferrand, Rashida A“…Multivariable logistic regression was used to investigate factors associated with mobile phone ownership and with internet access, with adjustment for the one-stage cluster sampling design. …”
Publicado 2021
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1550582por Hashemian, Seyed-Mohammad Reza, Aliannejad, Rasoul, Zarrabi, Morteza, Soleimani, Masoud, Vosough, Massoud, Hosseini, Seyedeh-Esmat, Hossieni, Hamed, Keshel, Saeid Heidari, Naderpour, Zeinab, Hajizadeh-Saffar, Ensiyeh, Shajareh, Elham, Jamaati, Hamidreza, Soufi-Zomorrod, Mina, Khavandgar, Naghmeh, Alemi, Hediyeh, Karimi, Aliasghar, Pak, Neda, Rouzbahani, Negin Hossieni, Nouri, Masoumeh, Sorouri, Majid, Kashani, Ladan, Madani, Hoda, Aghdami, Nasser, Vasei, Mohammad, Baharvand, Hossein“…A low percentage of lymphocytes (< 10%) and leukocytosis were associated with poor outcome (P = 0.02). All six survivors were well with no complaints of dyspnea on day 60 post-infusion. …”
Publicado 2021
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1550583por Chen, Xiaozheng, Gao, Aiqin, Zhang, Fang, Yang, Zijiang, Wang, Shuyun, Fang, Yuying, Li, Juan, Wang, Jingnan, Shi, Wenjing, Wang, Linlin, Zheng, Yan, Sun, Yuping“…The impact of ILT4 and PD-L1 on tumor-associated macrophage (TAM) recruitment and polarization was evaluated using Transwell migration assay, flow cytometry, enzyme linked immunosorbent assay (ELISA) and real-time PCR, while their impact on T cell survival and cytotoxicity was analyzed by CFSE proliferation assay, apoptotic assay, flow cytometry, ELISA and cytolytic assay. …”
Publicado 2021
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1550584por Dudnik, Elizabeth, Moskovitz, Mor, Rottenberg, Yakir, Lobachov, Anastasiya, Mandelboim, Rinat, Shochat, Tzippy, Urban, Damien, Wollner, Mira, Nechushtan, Hovav, Rotem, Ofer, Zer, Alona, Daher, Sameh, Bar, Jair“…In the real-world setting, no statistically significant differences in long-term outcomes with P vs PCT were observed; a prospective randomized trial addressing the comparative efficacy of P and PCT in different patient subgroups is highly anticipated.List of abbreviations: AE - adverse events; ALK - anaplastic lymphoma kinase gene; ALT - alanine aminotransferase; (a)NSCLC - (advanced) non-small cell lung cancer; AST - aspartate aminotransferase; BRAF - v-Raf murine sarcoma viral oncogene homolog B; BRCA2 - BReast CAncer gene 2; c-Met - tyrosine-protein kinase Met; CTCAE, v. 4.03 - Common Terminology Criteria for Adverse Events, version 4.03; CTLA-4 - cytotoxic T-lymphocyte-associated protein 4; ECOG PS - Eastern Cooperative Oncology Group performance status; EGFR - epidermal growth factor receptor gene; FISH - fluorescent in situ hybridization; HER2 - human epidermal growth factor receptor 2; IC - tumor-infiltrating immune cells; ICI - immune check-point inhibitors; IHC - immunohistochemistry; IQR - interquartile range; irAE - immune related adverse events; ISCORT - Israeli Society for Clinical Oncology and Radiotherapy; KRAS - Kirsten rat sarcoma viral oncogene homolog; (m)TTD -(median) time-to-treatment discontinuation; mo - months; (m)OS - (median) overall survival; (m)PFS - (median) progression-free survival; muts/Mb - mutations per megabase; NA - not specified/not available; NOS - not otherwise specified; NR - not reported/not reached; ORR - objective response rate; P - pembrolizumab; PCR - polymerase chain reaction; PCT - combination of pembrolizumab with platinum-based chemotherapy; PD – progression of disease; PD-1 - programmed cell death-1; PD-L1 - programmed cell death ligand-1; pts - patients; RET - proto-oncogene RET; ROS1 - proto-oncogene tyrosine-protein kinase ROS1; SD - standard deviation; STK11 - serine/threonine kinase 11; TC - tumor cells; TMB - Tumor mutation burden; TPS - tumor proportion score.…”
Publicado 2021
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1550585por Logunov, Denis Y, Dolzhikova, Inna V, Shcheblyakov, Dmitry V, Tukhvatulin, Amir I, Zubkova, Olga V, Dzharullaeva, Alina S, Kovyrshina, Anna V, Lubenets, Nadezhda L, Grousova, Daria M, Erokhova, Alina S, Botikov, Andrei G, Izhaeva, Fatima M, Popova, Olga, Ozharovskaya, Tatiana A, Esmagambetov, Ilias B, Favorskaya, Irina A, Zrelkin, Denis I, Voronina, Daria V, Shcherbinin, Dmitry N, Semikhin, Alexander S, Simakova, Yana V, Tokarskaya, Elizaveta A, Egorova, Daria A, Shmarov, Maksim M, Nikitenko, Natalia A, Gushchin, Vladimir A, Smolyarchuk, Elena A, Zyryanov, Sergey K, Borisevich, Sergei V, Naroditsky, Boris S, Gintsburg, Alexander L“…Most reported adverse events were grade 1 (7485 [94·0%] of 7966 total events). 45 (0·3%) of 16 427 participants in the vaccine group and 23 (0·4%) of 5435 participants in the placebo group had serious adverse events; none were considered associated with vaccination, with confirmation from the independent data monitoring committee. …”
Publicado 2021
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1550586por Filippelli, Mariaelena, Campagna, Giuseppe, Vito, Pasquale, Zotti, Tiziana, Ventre, Luca, Rinaldi, Michele, Bartollino, Silvia, dell'Omo, Roberto, Costagliola, Ciro“…Conclusions: Pro-inflammatory cytokines are associated with inflammation and angiogenesis, although there is a discrete variability in the doses of the mediators investigated among the different vitreous samples. …”
Publicado 2021
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1550587por Abd Elfatah, Khaled Saad, Elabasy, Moshira Abas, El-khyate, Faris, Elmahallawy, Ehab Kotb, Mosad, Samah M., El-Gohary, Fatma A., Abdo, Walied, Al-Brakati, Ashraf, Seadawy, Mohamed G., Tahoon, Abd Elnaby, El-Gohary, Abd Elgalil“…The histopathological findings of the experimentally infected chickens showed marked pulmonary congestion and pneumonia associated with complete bronchial stenosis. The spleen showed histocytic cell proliferation with marked lymphoid depletion, while the brain had malacia and diffuse gliosis. …”
Publicado 2021
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1550588por Adamson, Douglas, Byrne, Anthony, Porter, Catharine, Blazeby, Jane, Griffiths, Gareth, Nelson, Annmarie, Sewell, Bernadette, Jones, Mari, Svobodova, Martina, Fitzsimmons, Deborah, Nixon, Lisette, Fitzgibbon, Jim, Thomas, Stephen, Millin, Anthony, Crosby, Tom, Staffurth, John, Hurt, Christopher“…For a minority of patients clinically considered to be at high risk of tumour bleeding, concurrent palliative radiotherapy might reduce bleeding risk and the need for associated interventions. FUNDING: National Institute for Health Research Health Technology Assessment Programme.…”
Publicado 2021
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1550589por Stassen, H. H., Bachmann, S., Bridler, R., Cattapan, K., Herzig, D., Schneeberger, A., Seifritz, E.“…The study protocol included (1) assessment of previous history by the SADS Syndrome Check List SSCL-16 (lifetime version); (2) repeated measurements over 5 weeks assessing the time course of improvement by the Hamilton Depression Scale HAM-D and the Positive and Negative Syndrome Scale PANSS, along with medication and unwanted side effects through the Medication and Side Effects Inventory MEDIS; and (3) the collection of blood samples from which DNA and serum were extracted. The association between inflammatory response system and psychiatric disorders was detailed by fitting multi-layer Neural Net (NN) models to the observed data (“supervised learning”). …”
Publicado 2020
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1550590por Yaya, Sanni, Zegeye, Betregiorgis, Ahinkorah, Bright Opoku, Seidu, Abdul-Aziz, Ameyaw, Edward Kwabena, Adjei, Nicholas Kofi, Shibre, Gebretsadik“…This study sought to examine the factors associated with skilled childbirth services utilization among married women in Cameroon. …”
Publicado 2021
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1550591por Karkouti, Keyvan, Bartoszko, Justyna, Grewal, Deep, Bingley, Cielo, Armali, Chantal, Carroll, Jo, Hucke, Hans-Peter, Kron, Amie, McCluskey, Stuart A., Rao, Vivek, Callum, JeannieEnlace del recurso
Publicado 2021
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1550592por Yao, Ruofan, Martin, Courtney B., Haase, Victoria S., Tse, Beverly C., Nishino, Melissa, Gheorghe, Ciprian, Balli, Kevin“…Initial clinical characteristics identified at the time of diagnosis were compared between patients who required advanced respiratory support and those who were asymptomatic or had mild symptoms for those diagnosed during the period of April 2020 to November 2020. Risk factors associated with a requirement for advanced respiratory support were used to create the Obstetric Warning Score system. …”
Publicado 2021
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1550593por Petersen, Erika A., Stauss, Thomas G., Scowcroft, James A., Brooks, Elizabeth S., White, Judith L., Sills, Shawn M., Amirdelfan, Kasra, Guirguis, Maged N., Xu, Jijun, Yu, Cong, Nairizi, Ali, Patterson, Denis G., Tsoulfas, Kostandinos C., Creamer, Michael J., Galan, Vincent, Bundschu, Richard H., Paul, Christopher A., Mehta, Neel D., Choi, Heejung, Sayed, Dawood, Lad, Shivanand P., DiBenedetto, David J., Sethi, Khalid A., Goree, Johnathan H., Bennett, Matthew T., Harrison, Nathan J., Israel, Atef F., Chang, Paul, Wu, Paul W., Gekht, Gennady, Argoff, Charles E., Nasr, Christian E., Taylor, Rod S., Subbaroyan, Jeyakumar, Gliner, Bradford E., Caraway, David L., Mekhail, Nagy A.Enlace del recurso
Publicado 2021
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1550594por Finelli, Lyn, Gupta, Vikas, Petigara, Tanaz, Yu, Kalvin, Bauer, Karri A., Puzniak, Laura A.Enlace del recurso
Publicado 2021
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1550595“…BACKGROUND: Type 1 diabetes (T1DM) is associated with premature cardiovascular disease (CVD) and a pro-inflammatory state whilst the proangiogenic miR-126-3p/-5p may play a role in CVD. …”
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1550596por Shalaby, Reham, Vuong, Wesley, Hrabok, Marianne, Gusnowski, April, Mrklas, Kelly, Li, Daniel, Snaterse, Mark, Surood, Shireen, Cao, Bo, Li, Xin-Min, Greiner, Russell, Greenshaw, Andrew James, Agyapong, Vincent Israel Opoku“…This free service aims to promote psychological resilience and alleviate pandemic-associated stress, anxiety, and depression symptoms during the COVID-19 pandemic. …”
Publicado 2021
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1550597por Thombs, Brett D, Kwakkenbos, Linda, Levis, Brooke, Bourgeault, Angelica, Henry, Richard S, Levis, Alexander W, Harb, Sami, Tao, Lydia, Carrier, Marie-Eve, Bustamante, Laura, Duchek, Delaney, Dyas, Laura, El-Baalbaki, Ghassan, Ellis, Kelsey, Rice, Danielle B, Wurz, Amanda, Nordlund, Julia, Gagarine, Maria, Turner, Kimberly A, Østbø, Nora, Culos-Reed, Nicole, Hebblethwaite, Shannon, Patten, Scott, Bartlett, Susan J, Varga, John, Mouthon, Luc, Markham, Sarah, Martin, Michael S, Benedetti, Andrea“…FUNDING: Canadian Institutes of Health Research (CIHR; VR4-172745, MS1-173066); McGill Interdisciplinary Initiative in Infection and Immunity Emergency COVID-19 Research Fund; Scleroderma Canada, made possible by an educational grant for patient support programming from Boehringer Ingelheim; the Scleroderma Society of Ontario; Scleroderma Manitoba; Scleroderma Atlantic; Scleroderma Australia; Scleroderma New South Wales; Scleroderma Victoria; Scleroderma Queensland; Scleroderma SASK; the Scleroderma Association of BC; and Sclérodermie Québec.…”
Publicado 2021
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1550598por Pang, Hilary Y. M., Chalmers, Kelsey, Landon, Bruce, Elshaug, Adam G., Matelski, John, Ling, Vicki, Krzyzanowska, Monika K., Kulkarni, Girish, Erickson, Bradley A., Cram, PeterEnlace del recurso
Publicado 2021
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1550599por Ostheimer, C., Mäurer, M., Ebert, N., Schmitt, D., Krug, D., Baumann, R., Henkenberens, C., Giordano, F. A., Sautter, L., López, Guerra, Fleischmann, D. F., Niyazi, M., Käsmann, L., Kaul, D., Thieme, A. H., Billiet, C., Dobiasch, S., Arnold, C. R., Oertel, M., Haussmann, J., Gauer, T., Goy, Y., Suess, C., Ziegler, S., Panje, C. M., Baues, C., Trommer, M., Skripcak, T., Medenwald, D.“…In patients with available data on both GTV1 and GTV2, absolute GTV1 before RT was not significantly associated with survival (HR 0–69, 0.32–1.49, p > 0.05) but GTV2 significantly predicted OS in a model adjusted for age, T stage, and chemotherapy, with an HR of 3.7 (1.01–13.53, p = 0.04) per 300 ml. …”
Publicado 2021
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1550600por Jorge, Danilo Moyses, Tavares Neto, José Edísio da Silva, Poli-Neto, Omero Benedicto, Scott, Ingrid U., Jorge, Rodrigo“…CONCLUSION: PPV with preoperative IVB is associated with more rapid clearance of VH and improvement in BCVA than IVB injections alone. …”
Publicado 2021
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