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1550601por Menni, Cristina, Klaser, Kerstin, May, Anna, Polidori, Lorenzo, Capdevila, Joan, Louca, Panayiotis, Sudre, Carole H, Nguyen, Long H, Drew, David A, Merino, Jordi, Hu, Christina, Selvachandran, Somesh, Antonelli, Michela, Murray, Benjamin, Canas, Liane S, Molteni, Erika, Graham, Mark S, Modat, Marc, Joshi, Amit D, Mangino, Massimo, Hammers, Alexander, Goodman, Anna L, Chan, Andrew T, Wolf, Jonathan, Steves, Claire J, Valdes, Ana M, Ourselin, Sebastien, Spector, Tim D“…FUNDING: ZOE Global, National Institute for Health Research, Chronic Disease Research Foundation, National Institutes of Health, UK Medical Research Council, Wellcome Trust, UK Research and Innovation, American Gastroenterological Association.…”
Publicado 2021
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1550602por Lescure, François-Xavier, Honda, Hitoshi, Fowler, Robert A, Lazar, Jennifer Sloane, Shi, Genming, Wung, Peter, Patel, Naimish, Hagino, Owen“…BACKGROUND: Elevated proinflammatory cytokines are associated with greater COVID-19 severity. We aimed to assess safety and efficacy of sarilumab, an interleukin-6 receptor inhibitor, in patients with severe (requiring supplemental oxygen by nasal cannula or face mask) or critical (requiring greater supplemental oxygen, mechanical ventilation, or extracorporeal support) COVID-19. …”
Publicado 2021
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1550603“…This result may be associated with less corneal volume sculpted by laser for the higher astigmatism treatment, leading to fewer biochemical responses and les change in corneal aspherity. …”
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1550604por Hayes, Joseph F., Osborn, David P. J., Francis, Emma, Ambler, Gareth, Tomlinson, Laurie A., Boman, Magnus, Wong, Ian C. K., Geddes, John R., Dalman, Christina, Lewis, Glyn“…Notably, lithium duration and toxicity were not associated with high-risk trajectory.…”
Publicado 2021
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1550605por Limumpornpetch, Padiporn, Morgan, Ann W, Tiganescu, Ana, Nyaga, Victoria N, Rodriguez, Mar Pujades, Baxter, Paul D, Stewart, Paul Michael“…Background: Glucocorticoids (GCs) are widely used as therapeutic agents with prevalence 0.9–3.7%, but they are associated with significant side effects. Understanding of mortality ratios and causes of death from GC use is poorly appreciated and likely to help shape future stratification of clinical practice. …”
Publicado 2021
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1550606por de Freitas, Maria Cristina Foss, Akinci, Baris, Corsa, Callie, Rothberg, Amy E, MacDougald, Ormond A, Oral, Elif A“…Animal studies from our group have identified an association between adipose tissue loss and an increase in bone mineral density (BMD) in a mouse model with adipose tissue specific knockout of LMNA gene. …”
Publicado 2021
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1550607por Povaliaeva, Alexandra, Rozhinskaya, Liudmila Ya, Pigarova, Ekaterina A, Dzeranova, Larisa K, Katamadze, Nino N, Malysheva, Natalya, Nikankina, Larisa, Bogdanov, Viktor, Ioutsi, Vitaliy, Mokrysheva, Natalia G“…The observed profound vitamin D deficiency and association of vitamin D levels with markers of disease severity indicate the importance of vitamin D supplementation in these patients.…”
Publicado 2021
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1550608“…In pilot studies, early initiation of GH has been associated with favorable growth responses in short SGA children. …”
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1550609por Dichtel, Laura E, Subudhi, Sonu, Drescher, Hannah, Bartsch, Lea, Osganian, Stephanie, Chicote, Mark, Masia, Ricard, Bredella, Miriam, Bhatia, Sangeeta, Lauer, Georg, Miller, Karen Klahr, Corey, Kathleen“…This is consistent with our prior finding that histologic NASH and fibrosis are associated with lower serum IGF-1 levels. Moreover, we demonstrated that hepatic IGF-1R and GHR gene expression is not lower in liver tissue from patients with NAFLD and does not decline across disease severity. …”
Publicado 2021
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1550610“…Carrageenan-challenged experimental animals were screened for one inflammatory marker enzyme myeloperoxidase (MPO), inflammatory products such as Prostaglandrin E(2) (PGE(2)), and eight different cytokines markers (TNFα, IL-6, IFN γ, IL-1α, IL-1β, MCP-1, Rantes, and MIP) associated with inflammation reveals that LF (100 mg/kg, oral route) of Crateva adansonii shows prominent anti-inflammatory activity than reference standard indomethacin (10 mg/kg, oral route) over all these biological tested parameters. …”
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1550611Publicado 2021“…Hazard ratios (HR) associated with a reduction of systolic blood pressure by 5 mm Hg for a major cardiovascular event were 0·91, 95% CI 0·89–0·94 for partipants without previous cardiovascular disease and 0·89, 0·86–0·92, for those with previous cardiovascular disease. …”
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1550612por Główczyńska, Renata, Piotrowicz, Ewa, Szalewska, Dominika, Piotrowicz, Ryszard, Kowalik, Ilona, Pencina, Michael J., Zaręba, Wojciech, Banach, Maciej, Orzechowski, Piotr, Pluta, Sławomir, Irzmański, Robert, Kalarus, Zbigniew, Opolski, Grzegorz“…In contrast, among patients without DM, HCTR was associated with greater 9-week changes than UC in exercise time, which resulted in a statistically significant interaction between patients with and without DM: difference in changes in exercise time between HCTR versus UC was 12.0 s [95% CI − 15.1, 39.1 s] in DM and 43.1 s [95% CI 24.0, 63.0 s] in non-DM, interaction p-value = 0.016. …”
Publicado 2021
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1550613por Zhou, Zhi, Ni, Hai‐jian, Zhao, Wei, Gu, Guang‐fei, Chen, Jia, Zhu, Yan‐jie, Feng, Chao‐bo, Gong, Hao‐yu, Fan, Yun‐shan, He, Shi‐shengEnlace del recurso
Publicado 2021
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1550614por Zheng, Qing-yuan, Li, Rui, Ni, Ming, Ren, Peng, Ji, Quan-bo, Sun, Jing-yang, Li, Jun-cheng, Chen, Ji-ying, Zhang, Guo-qiangEnlace del recurso
Publicado 2021
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1550615por Jayaraman, Chandrasekaran, Mummidisetty, Chaithanya K., Albert, Mark V., Lipschutz, Robert, Hoppe-Ludwig, Shenan, Mathur, Gayatri, Jayaraman, Arun“…Trial registration This study is registered on clinical trials.gov with the study title “Functional outcomes in dysvascular transfemoral amputees” and the associated ClinicalTrials.gov Identifier: NCT01537211. …”
Publicado 2021
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1550616por Ku, Min-Chi, Kober, Frank, Lai, Yi-Ching, Pohlmann, Andreas, Qadri, Fatimunnisa, Bader, Michael, Carrier, Lucie, Niendorf, Thoralf“…This myocardial microvascular dysfunction was observed and associated with a reduction in regional MBF, mainly in the interventricular septal and inferior areas of the myocardium. …”
Publicado 2021
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1550617por Marty, Tom, Foulquié, Pierre, Dang-Vu, Laurent, Renner, Simon, Mebarki, Adel, Texier, Nathalie, Schück, Stéphane“…MATÉRIEL ET MÉTHODE: Les messages d’étudiants ont été recueillis sur le réseaux social Twitter de novembre 2020 au 31 janvier 2021 (mention du #ÉtudiantFantôme ou hashtag associé, ou mention du statut d’étudiant dans leur description). …”
Publicado 2021
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1550618por Bowman, Clive E.“…It is suggested that possible zoophagy (hypocarnivory) is associated with low chelal adductive force together with a small or large gape depending upon the size of the nematode being consumed. …”
Publicado 2021
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1550619por Bauer, Axel, Schreinlechner, Michael, Sappler, Nikolay, Dolejsi, Theresa, Tilg, Herbert, Aulinger, Benedikt A, Weiss, Günter, Bellmann-Weiler, Rosa, Adolf, Christian, Wolf, Dominik, Pirklbauer, Markus, Graziadei, Ivo, Gänzer, Hannes, von Bary, Christian, May, Andreas E, Wöll, Ewald, von Scheidt, Wolfgang, Rassaf, Tienush, Duerschmied, Daniel, Brenner, Christoph, Kääb, Stefan, Metzler, Bernhard, Joannidis, Michael, Kain, Hans-Ulrich, Kaiser, Norbert, Schwinger, Robert, Witzenbichler, Bernhard, Alber, Hannes, Straube, Florian, Hartmann, Niels, Achenbach, Stephan, von Bergwelt-Baildon, Michael, von Stülpnagel, Lukas, Schoenherr, Sebastian, Forer, Lukas, Embacher-Aichhorn, Sabine, Mansmann, Ulrich, Rizas, Konstantinos D, Massberg, Steffen“…Discontinuation was associated with a significantly lower AUC(SOFA) (0·00 [0·00–9·25] vs 3·50 [0·00–23·50]; p=0·040), mean SOFA score (0·00 [0·00–0·31] vs 0·12 [0·00–0·78]; p=0·040), and 30-day SOFA score (0·00 [10–90th percentile, 0·00–1·20] vs 0·00 [0·00–24·00]; p=0·023). …”
Publicado 2021
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1550620por Campi, Irene, Gennari, Luigi, Merlotti, Daniela, Mingiano, Christian, Frosali, Alessandro, Giovanelli, Luca, Torlasco, Camilla, Pengo, Martino F., Heilbron, Francesca, Soranna, Davide, Zambon, Antonella, Di Stefano, Marta, Aresta, Carmen, Bonomi, Marco, Cangiano, Biagio, Favero, Vittoria, Fatti, Letizia, Perego, Giovanni Battista, Chiodini, Iacopo, Parati, Gianfranco, Persani, Luca“…We aimed to assess if 25-hydroxyvitamin-D (25OHD) levels are associated with interleukin 6 (IL-6) levels and with disease severity and mortality in COVID-19. …”
Publicado 2021
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