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1551041por Maronpot, Robert R.“…The pre-genomic era was a time when toxicologic pathologists played a major role in drug development, evaluating the cancer bioassay and the associated dose-setting toxicity studies, and exploring the utility of proposed alternative animal models. …”
Publicado 2013
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1551042“…HES was significantly associated with more adverse events (5.3% versus 2.8%; P <0.001). …”
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1551043“…The objective of this study was to investigate if unblinding in randomized controlled trials (RCTs) is associated with enhanced placebo effects for intervention groups and nocebo effects for placebo groups. …”
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1551044por Nelson, Gregory, Fike, John, Limoli, Charles, Obenaus, André, Raber, Jacob, Soltesz, Ivan, Vlkolinský, Roman“…This suggests that in the DG the most sensitive targets may be GABA-ergic inhibitory neurons that regulate granular cell excitability. (28)Si ion effects appear to be associated with dendro-somatic coupling expected to affect signaling of the hippocampal neurons to other brain structures and vary between rostral and ventral hippocampal regions. …”
Publicado 2014
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1551045por Vasilopoulou, E., Loubière, L.S., Lash, G.E., Ohizua, O., McCabe, C.J., Franklyn, J.A., Kilby, M.D., Chan, S.Y.“…WHAT IS KNOWN ALREADY: Maternal thyroid dysfunction during early pregnancy is associated with complications of malplacentation including miscarriage and pre-eclampsia. …”
Publicado 2014
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1551046por Bancroft, Elizabeth K., Page, Elizabeth C., Castro, Elena, Lilja, Hans, Vickers, Andrew, Sjoberg, Daniel, Assel, Melissa, Foster, Christopher S., Mitchell, Gillian, Drew, Kate, Mæhle, Lovise, Axcrona, Karol, Evans, D. Gareth, Bulman, Barbara, Eccles, Diana, McBride, Donna, van Asperen, Christi, Vasen, Hans, Kiemeney, Lambertus A., Ringelberg, Janneke, Cybulski, Cezary, Wokolorczyk, Dominika, Selkirk, Christina, Hulick, Peter J., Bojesen, Anders, Skytte, Anne-Bine, Lam, Jimmy, Taylor, Louise, Oldenburg, Rogier, Cremers, Ruben, Verhaegh, Gerald, van Zelst-Stams, Wendy A., Oosterwijk, Jan C., Blanco, Ignacio, Salinas, Monica, Cook, Jackie, Rosario, Derek J., Buys, Saundra, Conner, Tom, Ausems, Margreet G., Ong, Kai-ren, Hoffman, Jonathan, Domchek, Susan, Powers, Jacquelyn, Teixeira, Manuel R., Maia, Sofia, Foulkes, William D., Taherian, Nassim, Ruijs, Marielle, den Enden, Apollonia T. Helderman-van, Izatt, Louise, Davidson, Rosemarie, Adank, Muriel A., Walker, Lisa, Schmutzler, Rita, Tucker, Kathy, Kirk, Judy, Hodgson, Shirley, Harris, Marion, Douglas, Fiona, Lindeman, Geoffrey J., Zgajnar, Janez, Tischkowitz, Marc, Clowes, Virginia E., Susman, Rachel, Ramón y Cajal, Teresa, Patcher, Nicholas, Gadea, Neus, Spigelman, Allan, van Os, Theo, Liljegren, Annelie, Side, Lucy, Brewer, Carole, Brady, Angela F., Donaldson, Alan, Stefansdottir, Vigdis, Friedman, Eitan, Chen-Shtoyerman, Rakefet, Amor, David J., Copakova, Lucia, Barwell, Julian, Giri, Veda N., Murthy, Vedang, Nicolai, Nicola, Teo, Soo-Hwang, Greenhalgh, Lynn, Strom, Sara, Henderson, Alex, McGrath, John, Gallagher, David, Aaronson, Neil, Ardern-Jones, Audrey, Bangma, Chris, Dearnaley, David, Costello, Philandra, Eyfjord, Jorunn, Rothwell, Jeanette, Falconer, Alison, Gronberg, Henrik, Hamdy, Freddie C., Johannsson, Oskar, Khoo, Vincent, Kote-Jarai, Zsofia, Lubinski, Jan, Axcrona, Ulrika, Melia, Jane, McKinley, Joanne, Mitra, Anita V., Moynihan, Clare, Rennert, Gad, Suri, Mohnish, Wilson, Penny, Killick, Emma, Moss, Sue, Eeles, Rosalind A.Enlace del recurso
Publicado 2014
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1551047por Vilchis, L Ignacio, Johnson, Christine K, Evenson, Joseph R, Pearson, Scott F, Barry, Karen L, Davidson, Peter, Raphael, Martin G, Gaydos, Joseph K“…Thus, we identified ecological traits and dietary specializations associated with species declines in a community of marine predators that could be reflective of ecosystem change. …”
Publicado 2015
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1551048“…Species with high SLA values were typically associated with faster growth rates, more rapid turnover of leaf material, and shorter lifespans than those species with low SLA. …”
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1551049por Ezebialu, Ifeanyichukwu U, Eke, Ahizechukwu C, Eleje, George U, Nwachukwu, Chukwuemeka E“…Whilst use of TVUS was associated with an increased need for misoprostol for cervical ripening, both methods could be complementary. …”
Publicado 2015
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1551050por Widyastuti, Maria Digna Winda, Bardosh, Kevin Louis, Sunandar, ᅟ, Basri, C., Basuno, E., Jatikusumah, A., Arief, R. A., Putra, A. A. G., Rukmantara, A., Estoepangestie, A. T. S., Willyanto, I., Natakesuma, I. K. G., Sumantra, I. P., Grace, D., Unger, F., Gilbert, J.“…The level of community knowledge about rabies and its associated control programs were generally fair and community attitudes were positive. …”
Publicado 2015
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1551051por Capalbo, Antonio, Ubaldi, Filippo Maria, Cimadomo, Danilo, Maggiulli, Roberta, Patassini, Cristina, Dusi, Ludovica, Sanges, Federica, Buffo, Laura, Venturella, Roberta, Rienzi, Laura“…Higher cellularity was significantly associated with a better quality of the CCS diagnosis (P < 0.01) and with the conclusive diagnosis rate, with nonconcurrent samples showing significantly lower numbers of cells (2.1; 95% CI=1.5–2.7) compared with samples resulting in a conclusive diagnosis (mean cells number 7.5; 95% CI = 7.1–7.9, P < 0.01). …”
Publicado 2016
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1551052por LaRocco, Mark T., Franek, Jacob, Leibach, Elizabeth K., Weissfeld, Alice S., Kraft, Colleen S., Sautter, Robert L., Baselski, Vickie, Rodahl, Debra, Peterson, Edward J., Cornish, Nancy E.“…The purposes of this review were to identify and evaluate preanalytic practices associated with urine specimens and to assess their impact on the accuracy of urine culture microbiology. …”
Publicado 2015
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1551053por Kocagoz, Sevi B., Underwood, Richard J., MacDonald, Daniel W., Gilbert, Jeremy L., Kurtz, Steven M.“…QUESTIONS/PURPOSES: We asked: (1) Do ceramic heads result in less volume of material loss at the head-stem junction compared with CoCr heads; (2) do stem cone tapers have less volumetric material loss compared with CoCr head bore tapers; (3) do visual fretting-corrosion scores correlate with volumetric material loss; and (4) are device, patient, or intraoperative factors associated with volumetric material loss? METHODS: A quantitative method was developed to estimate volumetric material loss from the head and stem taper in previously matched cohorts of 50 ceramic and 50 CoCr head-stem pairs retrieved during revision surgery for causes not related to adverse reactions to metal particles. …”
Publicado 2016
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1551054por Malhi, Gin S., Byrow, Yulisha, Cassidy, Frederick, Cipriani, Andrea, Demyttenaere, Koen, Frye, Mark A., Gitlin, Michael, Kennedy, Sidney H., Ketter, Terence A., Lam, Raymond W., McShane, Rupert, Mitchell, Alex J., Ostacher, Michael J., Rizvi, Sakina J., Thase, Michael E., Tohen, Mauricio“…Honoraria for speaking/advising/consulting, and/or received research funds: AstraZeneca, Brain Canada, Bristol Myers Squibb, Canadian Institutes of Health Research, Canadian Depression Research and Intervention Network, Canadian Network for Mood and Anxiety Treatments, Canadian Psychiatric Association, Coast Capital Savings, Johnson and Johnson, Lundbeck, Lundbeck Institute, Pfizer, Servier, St. …”
Publicado 2016
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1551055“…We searched another 23 websites and online databases for grey literature up to August 2015, including the World Bank, the International Monetary Fund, the U4 Anti‐Corruption Resource Centre, Transparency International, healthcare anti‐fraud association websites and trial registries. We conducted citation searches in Science Citation Index and Google Scholar, and searched PubMed for related articles up to August 2015. …”
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1551056por Ascierto, Paolo A., Agarwala, Sanjiv, Botti, Gerardo, Cesano, Alessandra, Ciliberto, Gennaro, Davies, Michael A., Demaria, Sandra, Dummer, Reinhard, Eggermont, Alexander M., Ferrone, Soldano, Fu, Yang Xin, Gajewski, Thomas F., Garbe, Claus, Huber, Veronica, Khleif, Samir, Krauthammer, Michael, Lo, Roger S., Masucci, Giuseppe, Palmieri, Giuseppe, Postow, Michael, Puzanov, Igor, Silk, Ann, Spranger, Stefani, Stroncek, David F., Tarhini, Ahmad, Taube, Janis M., Testori, Alessandro, Wang, Ena, Wargo, Jennifer A., Yee, Cassian, Zarour, Hassane, Zitvogel, Laurence, Fox, Bernard A., Mozzillo, Nicola, Marincola, Francesco M., Thurin, Magdalena“…Specifically, many clinical successes have been using checkpoint receptor blockade, including T cell inhibitory receptors such as cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) and the programmed cell death-1 (PD-1) and its ligand PD-L1. …”
Publicado 2016
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1551057por Silver, Lynn D., Ng, Shu Wen, Ryan-Ibarra, Suzanne, Taillie, Lindsey Smith, Induni, Marta, Miles, Donna R., Poti, Jennifer M., Popkin, Barry M.“…This study examines the association of the first penny per ounce SSB excise tax in the United States, in Berkeley, California, with beverage prices, sales, store revenue/consumer spending, and usual beverage intake. …”
Publicado 2017
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1551058“…In the single large trial from Afghanistan, the trial authors reported that vitamin D supplementation was associated with an increase in repeat episodes of pneumonia confirmed by chest radiograph (RR 1.69, 95% CI 1.28 to 2.21; one trial, 3046 participants), but not reflected in the outcome of confirmed or unconfirmed pneumonia (RR 1.06, 95% CI 1.00 to 1.13; one trial, 3046 participants). …”
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1551059por Kinenkinda, Xavier, Mukuku, Olivier, Chenge, Faustin, Kakudji, Prosper, Banzulu, Peter, Kakoma, Jean-Baptiste, Kizonde, Justin“…CONCLUSION: This study shows that cesarean section in our working condition is associated to a significant maternal and perinatal mortality. …”
Publicado 2017
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1551060por Perl, Alexander E., Altman, Jessica K., Cortes, Jorge, Smith, Catherine, Litzow, Mark, Baer, Maria R., Claxton, David, Erba, Harry P., Gill, Stan, Goldberg, Stuart, Jurcic, Joseph G., Larson, Richard A., Liu, Chaofeng, Ritchie, Ellen, Schiller, Gary, Spira, Alexander I., Strickland, Stephen A., Tibes, Raoul, Ustun, Celalettin, Wang, Eunice S., Stuart, Robert, Röllig, Christoph, Neubauer, Andreas, Martinelli, Giovanni, Bahceci, Erkut, Levis, Mark“…BACKGROUND: Fms-like tyrosine kinase 3-internal tandem duplication (FLT3-ITD) mutations are common in acute myeloid leukemia (AML) and are associated with rapid relapse and short survival. In relapsed/refractory (R/R) AML, the clinical benefit of FLT3 inhibitors has been limited by rapid generation of resistance mutations, especially FLT3-D835. …”
Publicado 2017
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