“…On the univariate analysis, the following variables were significantly associated with BFFS: PSA at diagnosis; clinical stage (cT1 vs cT2); GS at diagnosis; treatment indication (ART vs SRT); pre-RT PSA levels; and RT dose 66 -68 Gy vs. 72 Gy (HR: 2.05; 95%CI: 1.02-4.02, P = 0.04). …”
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“…Production of TNFα by whole blood in response to LPS was associated with serum tH3(24hrs) (r(2) = 0.67). Diminished H3K4me3(24hrs,) H3K27ac(24hrs), and H3K27ac(3m), accompanied the emergence of liver failure. …”
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“…CONCLUSIONS: This study highlights that eight proteins, TNC, FSCN1, SERPINB1, ACTN1, RAB31, COL3A1, COL1A1, CD36, were significantly associated with the mechanisms of invasion and metastasis in Bowen’s disease. …”
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“…STUDY FUNDING/COMPETING INTEREST(S): The ARTCC programme was developed and funded by ESHRE, covering expenses associated with the meetings. The Steering Committee members who are the authors of this article did not receive payments for the completion of this study. …”
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“…A variety of microbes can trigger HLA B27 non-associated reactive arthritis, in which a polyarthritis is more common compared to oligoarthritis. …”
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“…PET CT was performed which showed increased uptake affecting the outer ears bilaterally and suggestion of low- grade uptake associated with the costal cartilages and more apparent xiphisternal uptake, suggestive of RP. …”
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“…It is important that as many children as possible are able to avoid the risks associated with general anaesthetic. Virtual reality was very successful in enabling a young person to have a positive experience of a intraarticular corticosteroid injection having previously been anxious about this treatment. …”
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“…PROBLEM/CONDITION: Sickle cell disease (SCD), an inherited blood disorder affecting an estimated 100,000 persons in the United States, is associated with multiple complications and reduced life expectancy. …”
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“…DESCRIPTION/METHOD: The Children’s Chronic Arthritis Association (CCAA) is a charity offering support to families living with JIA in the UK. …”
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“…Ainsi, chaque patient se voit associé un niveau de risque (une probabilité d'être un cas sévère) et un score de contribution de chacune de ses variables explicatives, permettant de repérer les facteurs de protection et de risque. …”
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“…METHODS: This study is an ongoing, randomised, double-blind, multicentre, active-controlled, phase 3, non-inferiority trial done at 94 community, public health, and hospital-associated clinics located in regions of Europe and North America, where there is a high incidence of HIV or prevalence of people living with HIV, or both. …”
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“…RESULTS: Among those 247 patients with MHD, compared with baseline levels, systolic blood pressure (BP) (149.7 ± 23.6 vs. 137.2 ± 21.0 mmHg, P < 0.001), diastolic BP (90.2 ± 16.1 vs. 84.5 ± 14.1 mmHg, P < 0.001), heart rate (83.5 ± 12.5 vs. 80.0 ± 8.7 bpm, P < 0.001), N-terminal B-type natriuretic peptide precursor (NT-proBNP) [29125.0 (11474.5, 68532.0) vs. 12561.3 (4035.0, 37575.0) pg/ml, P < 0.001], and cardiac troponin I [0.044 (0.025, 0.078) vs. 0.0370 (0.020, 0.064) μg/L, P = 0.009] were markedly decreased after treatment with sacubitril/valsartan. New York Heart Association (NYHA) functional class showed a notable trend of improvement after 3–12 months of follow-up. …”
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“…BACKGROUND: Antipsychotic drugs are the mainstay treatment for schizophrenia, yet they are associated with diverse and potentially dose‐related side effects which can reduce quality of life. …”
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“…However, some studies have found 2MN to be associated with impaired implantation and live birth. …”
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“…Exclusion criteria: oncology patients, genetic disorders affecting the musculoskeletal system, paralysis or inability to move upper extremity prior or after injury, additional ipsilateral upper limb fractures, open injuries, associated vascular injuries as well brachial plexus injuries and nerve damages. …”
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“…CONCLUSION: Il n’existe pas de données définitives indiquant que les vaccins à ARNm seraient responsables du développement d’une auto-immunité, néanmoins la chronologie de la survenue des symptômes fait suggérer une possible association éthiopathogénique entre l’administration du vaccin et la survenue d’un lupus chez des sujets génétiquement prédisposés. …”
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“…Nos objectifs étaient d’évaluer ce risque et de rechercher les facteurs associés à une poussée de LES après un épisode sévère de COVID-19. …”
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“…Concernant la proportion de cellules T auto-réactives des patients lupiques, nous avons observé, qu’après une hausse non significative entre T0 et M1, les cellules auto-réactives diminuaient significativement dans le temps (coefficient β d l’effet fixe associé au temps dans le modèle linéaire à effet mixte = −0,00067, p = 0,015). …”
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“…INTERPRETATION: A single dose of nirsevimab protected healthy infants born at term or preterm from medically attended RSV LRTI, associated hospital admission, and severe RSV. Pharmacokinetic data support efficacy extrapolation to infants with chronic lung disease, congenital heart disease, or extreme prematurity. …”
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