Genome-wide scan identifies CDH13 as a novel susceptibility locus contributing to blood pressure determination in two European populations

por Org, Elin, Eyheramendy, Susana, Juhanson, Peeter, Gieger, Christian, Lichtner, Peter, Klopp, Norman, Veldre, Gudrun, Döring, Angela, Viigimaa, Margus, Sõber, Siim, Tomberg, Kärt, Eckstein, Gertrud, Kelgo, Piret, Rebane, Tiina, Shaw-Hawkins, Sue, Howard, Philip, Onipinla, Abiodun, Dobson, Richard J., Newhouse, Stephen J., Brown, Morris, Dominiczak, Anna, Connell, John, Samani, Nilesh, Farrall, Martin, Caulfield, Mark J., Munroe, Patricia B., Illig, Thomas, Wichmann, H.-Erich, Meitinger, Thomas, Laan, Maris
Publicado 2009

Integrated associations of genotypes with multiple blood biomarkers linked to coronary heart disease risk

por Drenos, Fotios, Talmud, Philippa J., Casas, Juan P., Smeeth, Liam, Palmen, Jutta, Humphries, Steve E., Hingorani, Aroon D.
Publicado 2009

Identification of AF4/FMR2 family, member 3 (AFF3) as a novel rheumatoid arthritis susceptibility locus and confirmation of two further pan-autoimmune susceptibility genes

por Barton, Anne, Eyre, Steve, Ke, Xiayi, Hinks, Anne, Bowes, John, Flynn, Edward, Martin, Paul, Wilson, Anthony G., Morgan, Ann W., Emery, Paul, Steer, Sophia, Hocking, Lynne J., Reid, David M., Harrison, Pille, Wordsworth, Paul, Thomson, Wendy, Worthington, Jane
Publicado 2009

Positive selection of a CD36 nonsense variant in sub-Saharan Africa, but no association with severe malaria phenotypes

por Fry, Andrew E., Ghansa, Anita, Small, Kerrin S., Palma, Alejandro, Auburn, Sarah, Diakite, Mahamadou, Green, Angela, Campino, Susana, Teo, Yik Y., Clark, Taane G., Jeffreys, Anna E., Wilson, Jonathan, Jallow, Muminatou, Sisay-Joof, Fatou, Pinder, Margaret, Griffiths, Michael J., Peshu, Norbert, Williams, Thomas N., Newton, Charles R., Marsh, Kevin, Molyneux, Malcolm E., Taylor, Terrie E., Koram, Kwadwo A., Oduro, Abraham R., Rogers, William O., Rockett, Kirk A., Sabeti, Pardis C., Kwiatkowski, Dominic P.
Publicado 2009

Combined effects of three independent SNPs greatly increase the risk estimate for RA at 6q23

por Orozco, Gisela, Hinks, Anne, Eyre, Steve, Ke, Xiayi, Gibbons, Laura J., Bowes, John, Flynn, Edward, Martin, Paul, Wilson, Anthony G., Bax, Deborah E., Morgan, Ann W., Emery, Paul, Steer, Sophia, Hocking, Lynne, Reid, David M., Wordsworth, Paul, Harrison, Pille, Thomson, Wendy, Barton, Anne, Worthington, Jane
Publicado 2009

A common genetic variant in the 15q24 nicotinic acetylcholine receptor gene cluster (CHRNA5–CHRNA3–CHRNB4) is associated with a reduced ability of women to quit smoking in pregnancy

por Freathy, Rachel M., Ring, Susan M., Shields, Beverley, Galobardes, Bruna, Knight, Beatrice, Weedon, Michael N., Smith, George Davey, Frayling, Timothy M., Hattersley, Andrew T.
Publicado 2009

A polygenic basis for four classical Fredrickson hyperlipoproteinemia phenotypes that are characterized by hypertriglyceridemia

por Hegele, Robert A., Ban, Matthew R., Hsueh, Neil, Kennedy, Brooke A., Cao, Henian, Zou, Guang Yong, Anand, Sonia, Yusuf, Salim, Huff, Murray W., Wang, Jian
Publicado 2009

Investigating the genetic association between ERAP1 and ankylosing spondylitis

por Harvey, David, Pointon, Jennifer J., Evans, David M., Karaderi, Tugce, Farrar, Claire, Appleton, Louise H., Sturrock, Roger D., Stone, Millicent A., Oppermann, Udo, Brown, Matthew A., Wordsworth, B. Paul
Publicado 2009

A non-synonymous variant in ADH1B is strongly associated with prenatal alcohol use in a European sample of pregnant women

por Zuccolo, Luisa, Fitz-Simon, Nicola, Gray, Ron, Ring, Susan M., Sayal, Kapil, Smith, George Davey, Lewis, Sarah J.
Publicado 2009

Life course variations in the associations between FTO and MC4R gene variants and body size

por Hardy, Rebecca, Wills, Andrew K., Wong, Andrew, Elks, Cathy E., Wareham, Nicholas J., Loos, Ruth J.F., Kuh, Diana, Ong, Ken K.
Publicado 2010

Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes

por Perry, John R.B., Weedon, Michael N., Langenberg, Claudia, Jackson, Anne U., Lyssenko, Valeriya, Sparsø, Thomas, Thorleifsson, Gudmar, Grallert, Harald, Ferrucci, Luigi, Maggio, Marcello, Paolisso, Giuseppe, Walker, Mark, Palmer, Colin N.A., Payne, Felicity, Young, Elizabeth, Herder, Christian, Narisu, Narisu, Morken, Mario A., Bonnycastle, Lori L., Owen, Katharine R., Shields, Beverley, Knight, Beatrice, Bennett, Amanda, Groves, Christopher J., Ruokonen, Aimo, Jarvelin, Marjo Riitta, Pearson, Ewan, Pascoe, Laura, Ferrannini, Ele, Bornstein, Stefan R., Stringham, Heather M., Scott, Laura J., Kuusisto, Johanna, Nilsson, Peter, Neptin, Malin, Gjesing, Anette P., Pisinger, Charlotta, Lauritzen, Torsten, Sandbaek, Annelli, Sampson, Mike, Zeggini, MAGIC, Ele, Lindgren, Cecilia M., Steinthorsdottir, Valgerdur, Thorsteinsdottir, Unnur, Hansen, Torben, Schwarz, Peter, Illig, Thomas, Laakso, Markku, Stefansson, Kari, Morris, Andrew D., Groop, Leif, Pedersen, Oluf, Boehnke, Michael, Barroso, Inês, Wareham, Nicholas J., Hattersley, Andrew T., McCarthy, Mark I., Frayling, Timothy M.
Publicado 2010

An integrated expression phenotype mapping approach defines common variants in LEP, ALOX15 and CAPNS1 associated with induction of IL-6

por Fairfax, Benjamin P., Vannberg, Fredrik O., Radhakrishnan, Jayachandran, Hakonarson, Hakon, Keating, Brendan J., Hill, Adrian V.S., Knight, Julian C.
Publicado 2010

Comprehensive follow-up of the first genome-wide association study of multiple sclerosis identifies KIF21B and TMEM39A as susceptibility loci

por McCauley, Jacob L., Zuvich, Rebecca L., Beecham, Ashley H., De Jager, Philip L., Konidari, Ioanna, Whitehead, Patrice L., Aubin, Cristin, Ban, Maria, Pobywajlo, Susan, Briskin, Rebeccah, Romano, Susan, Aggarwal, Neelum T., Piccio, Laura, McArdle, Wendy L., Strachan, David P., Evans, Denis, Cross, Anne H., Cree, Bruce, Rioux, John D., Barcellos, Lisa F., Ivinson, Adrian J., Compston, Alastair, Hafler, David A., Hauser, Stephen L., Oksenberg, Jorge R., Sawcer, Stephen J., Pericak-Vance, Margaret A., Haines, Jonathan L.
Publicado 2010

European lactase persistence genotype shows evidence of association with increase in body mass index

por Kettunen, Johannes, Silander, Kaisa, Saarela, Olli, Amin, Najaf, Müller, Martina, Timpson, Nicholas, Surakka, Ida, Ripatti, Samuli, Laitinen, Jaana, Hartikainen, Anna-Liisa, Pouta, Anneli, Lahermo, Päivi, Anttila, Verneri, Männistö, Satu, Jula, Antti, Virtamo, Jarmo, Salomaa, Veikko, Lehtimäki, Terho, Raitakari, Olli, Gieger, Christian, Wichmann, Erich H., Van Duijn, Cornelia M., Smith, George Davey, McCarthy, Mark I., Järvelin, Marjo-Riitta, Perola, Markus, Peltonen, Leena
Publicado 2010

Dense mapping of MYH9 localizes the strongest kidney disease associations to the region of introns 13 to 15

por Nelson, George W., Freedman, Barry I., Bowden, Donald W., Langefeld, Carl D., An, Ping, Hicks, Pamela J., Bostrom, Meredith A., Johnson, Randall C., Kopp, Jeffrey B., Winkler, Cheryl A.
Publicado 2010

African ancestry allelic variation at the MYH9 gene contributes to increased susceptibility to non-diabetic end-stage kidney disease in Hispanic Americans

por Behar, Doron M., Rosset, Saharon, Tzur, Shay, Selig, Sara, Yudkovsky, Guennady, Bercovici, Sivan, Kopp, Jeffrey B., Winkler, Cheryl A., Nelson, George W., Wasser, Walter G., Skorecki, Karl
Publicado 2010

Independent and population-specific association of risk variants at the IRGM locus with Crohn's disease

por Prescott, Natalie J., Dominy, Katherine M., Kubo, Michiaki, Lewis, Cathryn M., Fisher, Sheila A., Redon, Richard, Huang, Ni, Stranger, Barbara E., Blaszczyk, Katarzyna, Hudspith, Barry, Parkes, Gareth, Hosono, Naoya, Yamazaki, Keiko, Onnie, Clive M., Forbes, Alastair, Dermitzakis, Emmanouil T., Nakamura, Yusuke, Mansfield, John C., Sanderson, Jeremy, Hurles, Matthew E., Roberts, Roland G., Mathew, Christopher G.
Publicado 2010

Genome-wide association identifies ATOH7 as a major gene determining human optic disc size

por Macgregor, Stuart, Hewitt, Alex W., Hysi, Pirro G., Ruddle, Jonathan B., Medland, Sarah E., Henders, Anjali K., Gordon, Scott D., Andrew, Toby, McEvoy, Brian, Sanfilippo, Paul G., Carbonaro, Francis, Tah, Vikas, Li, Yi Ju, Bennett, Sonya L., Craig, Jamie E., Montgomery, Grant W., Tran-Viet, Khanh-Nhat, Brown, Nadean L., Spector, Timothy D., Martin, Nicholas G., Young, Terri L., Hammond, Christopher J., Mackey, David A.
Publicado 2010

Genome-wide association study of circulating vitamin D levels

por Ahn, Jiyoung, Yu, Kai, Stolzenberg-Solomon, Rachael, Simon, K. Claire, McCullough, Marjorie L., Gallicchio, Lisa, Jacobs, Eric J., Ascherio, Alberto, Helzlsouer, Kathy, Jacobs, Kevin B., Li, Qizhai, Weinstein, Stephanie J., Purdue, Mark, Virtamo, Jarmo, Horst, Ronald, Wheeler, William, Chanock, Stephen, Hunter, David J., Hayes, Richard B., Kraft, Peter, Albanes, Demetrius
Publicado 2010

Copy number, linkage disequilibrium and disease association in the FCGR locus

por Niederer, Heather A., Willcocks, Lisa C., Rayner, Tim F., Yang, Wanling, Lau, Yu Lung, Williams, Thomas N., Scott, J. Anthony G., Urban, Britta C., Peshu, Norbert, Dunstan, Sarah J., Hien, Tran Tinh, Phu, Nguyen Hoan, Padyukov, Leonid, Gunnarsson, Iva, Svenungsson, Elisabet, Savage, Caroline O., Watts, Richard A., Lyons, Paul A., Clayton, David G., Smith, Kenneth G.C.
Publicado 2010