Fine-mapping identifies two additional breast cancer susceptibility loci at 9q31.2

por Orr, Nick, Dudbridge, Frank, Dryden, Nicola, Maguire, Sarah, Novo, Daniela, Perrakis, Eleni, Johnson, Nichola, Ghoussaini, Maya, Hopper, John L., Southey, Melissa C., Apicella, Carmel, Stone, Jennifer, Schmidt, Marjanka K., Broeks, Annegien, Van't Veer, Laura J., Hogervorst, Frans B., Fasching, Peter A., Haeberle, Lothar, Ekici, Arif B., Beckmann, Matthias W., Gibson, Lorna, Aitken, Zoe, Warren, Helen, Sawyer, Elinor, Tomlinson, Ian, Kerin, Michael J., Miller, Nicola, Burwinkel, Barbara, Marme, Frederik, Schneeweiss, Andreas, Sohn, Chistof, Guénel, Pascal, Truong, Thérèse, Cordina-Duverger, Emilie, Sanchez, Marie, Bojesen, Stig E., Nordestgaard, Børge G., Nielsen, Sune F., Flyger, Henrik, Benitez, Javier, Zamora, Maria Pilar, Arias Perez, Jose Ignacio, Menéndez, Primitiva, Anton-Culver, Hoda, Neuhausen, Susan L., Brenner, Hermann, Dieffenbach, Aida Karina, Arndt, Volker, Stegmaier, Christa, Hamann, Ute, Brauch, Hiltrud, Justenhoven, Christina, Brüning, Thomas, Ko, Yon-Dschun, Nevanlinna, Heli, Aittomäki, Kristiina, Blomqvist, Carl, Khan, Sofia, Bogdanova, Natalia, Dörk, Thilo, Lindblom, Annika, Margolin, Sara, Mannermaa, Arto, Kataja, Vesa, Kosma, Veli-Matti, Hartikainen, Jaana M., Chenevix-Trench, Georgia, Beesley, Jonathan, Lambrechts, Diether, Moisse, Matthieu, Floris, Guiseppe, Beuselinck, Benoit, Chang-Claude, Jenny, Rudolph, Anja, Seibold, Petra, Flesch-Janys, Dieter, Radice, Paolo, Peterlongo, Paolo, Peissel, Bernard, Pensotti, Valeria, Couch, Fergus J., Olson, Janet E., Slettedahl, Seth, Vachon, Celine, Giles, Graham G., Milne, Roger L., McLean, Catriona, Haiman, Christopher A., Henderson, Brian E., Schumacher, Fredrick, Le Marchand, Loic, Simard, Jacques, Goldberg, Mark S., Labrèche, France, Dumont, Martine, Kristensen, Vessela, Alnæs, Grethe Grenaker, Nord, Silje, Borresen-Dale, Anne-Lise, Zheng, Wei, Deming-Halverson, Sandra, Shrubsole, Martha, Long, Jirong, Winqvist, Robert, Pylkäs, Katri, Jukkola-Vuorinen, Arja, Grip, Mervi, Andrulis, Irene L., Knight, Julia A., Glendon, Gord, Tchatchou, Sandrine, Devilee, Peter, Tollenaar, Robertus A. E. M., Seynaeve, Caroline M., Van Asperen, Christi J., Garcia-Closas, Montserrat, Figueroa, Jonine, Chanock, Stephen J., Lissowska, Jolanta, Czene, Kamila, Darabi, Hatef, Eriksson, Mikael, Klevebring, Daniel, Hooning, Maartje J., Hollestelle, Antoinette, van Deurzen, Carolien H. M., Kriege, Mieke, Hall, Per, Li, Jingmei, Liu, Jianjun, Humphreys, Keith, Cox, Angela, Cross, Simon S., Reed, Malcolm W. R., Pharoah, Paul D. P., Dunning, Alison M., Shah, Mitul, Perkins, Barbara J., Jakubowska, Anna, Lubinski, Jan, Jaworska-Bieniek, Katarzyna, Durda, Katarzyna, Ashworth, Alan, Swerdlow, Anthony, Jones, Michael, Schoemaker, Minouk J., Meindl, Alfons, Schmutzler, Rita K., Olswold, Curtis, Slager, Susan, Toland, Amanda E., Yannoukakos, Drakoulis, Muir, Kenneth, Lophatananon, Artitaya, Stewart-Brown, Sarah, Siriwanarangsan, Pornthep, Matsuo, Keitaro, Ito, Hidema, Iwata, Hiroji, Ishiguro, Junko, Wu, Anna H., Tseng, Chiu-chen, Van Den Berg, David, Stram, Daniel O., Teo, Soo Hwang, Yip, Cheng Har, Kang, Peter, Ikram, Mohammad Kamran, Shu, Xiao-Ou, Lu, Wei, Gao, Yu-Tang, Cai, Hui, Kang, Daehee, Choi, Ji-Yeob, Park, Sue K., Noh, Dong-Young, Hartman, Mikael, Miao, Hui, Lim, Wei Yen, Lee, Soo Chin, Sangrajrang, Suleeporn, Gaborieau, Valerie, Brennan, Paul, Mckay, James, Wu, Pei-Ei, Hou, Ming-Feng, Yu, Jyh-Cherng, Shen, Chen-Yang, Blot, William, Cai, Qiuyin, Signorello, Lisa B., Luccarini, Craig, Bayes, Caroline, Ahmed, Shahana, Maranian, Mel, Healey, Catherine S., González-Neira, Anna, Pita, Guillermo, Alonso, M. Rosario, Álvarez, Nuria, Herrero, Daniel, Tessier, Daniel C., Vincent, Daniel, Bacot, Francois, Hunter, David J., Lindstrom, Sara, Dennis, Joe, Michailidou, Kyriaki, Bolla, Manjeet K., Easton, Douglas F., dos Santos Silva, Isabel, Fletcher, Olivia, Peto, Julian
Publicado 2015

Targeted sequencing of the Paget's disease associated 14q32 locus identifies several missense coding variants in RIN3 that predispose to Paget's disease of bone

por Vallet, Mahéva, Soares, Dinesh C., Wani, Sachin, Sophocleous, Antonia, Warner, Jon, Salter, Donald M., Ralston, Stuart H., Albagha, Omar M.E.
Publicado 2015

A novel common variant in DCST2 is associated with length in early life and height in adulthood

por van der Valk, Ralf J.P., Kreiner-Møller, Eskil, Kooijman, Marjolein N., Guxens, Mònica, Stergiakouli, Evangelia, Sääf, Annika, Bradfield, Jonathan P., Geller, Frank, Hayes, M. Geoffrey, Cousminer, Diana L., Körner, Antje, Thiering, Elisabeth, Curtin, John A., Myhre, Ronny, Huikari, Ville, Joro, Raimo, Kerkhof, Marjan, Warrington, Nicole M., Pitkänen, Niina, Ntalla, Ioanna, Horikoshi, Momoko, Veijola, Riitta, Freathy, Rachel M., Teo, Yik-Ying, Barton, Sheila J., Evans, David M., Kemp, John P., St Pourcain, Beate, Ring, Susan M., Davey Smith, George, Bergström, Anna, Kull, Inger, Hakonarson, Hakon, Mentch, Frank D., Bisgaard, Hans, Chawes, Bo, Stokholm, Jakob, Waage, Johannes, Eriksen, Patrick, Sevelsted, Astrid, Melbye, Mads, van Duijn, Cornelia M., Medina-Gomez, Carolina, Hofman, Albert, de Jongste, Johan C., Taal, H. Rob, Uitterlinden, André G., Armstrong, Loren L., Eriksson, Johan, Palotie, Aarno, Bustamante, Mariona, Estivill, Xavier, Gonzalez, Juan R., Llop, Sabrina, Kiess, Wieland, Mahajan, Anubha, Flexeder, Claudia, Tiesler, Carla M.T., Murray, Clare S., Simpson, Angela, Magnus, Per, Sengpiel, Verena, Hartikainen, Anna-Liisa, Keinanen-Kiukaanniemi, Sirkka, Lewin, Alexandra, Da Silva Couto Alves, Alexessander, Blakemore, Alexandra I., Buxton, Jessica L., Kaakinen, Marika, Rodriguez, Alina, Sebert, Sylvain, Vaarasmaki, Marja, Lakka, Timo, Lindi, Virpi, Gehring, Ulrike, Postma, Dirkje S., Ang, Wei, Newnham, John P., Lyytikäinen, Leo-Pekka, Pahkala, Katja, Raitakari, Olli T., Panoutsopoulou, Kalliope, Zeggini, Eleftheria, Boomsma, Dorret I., Groen-Blokhuis, Maria, Ilonen, Jorma, Franke, Lude, Hirschhorn, Joel N., Pers, Tune H., Liang, Liming, Huang, Jinyan, Hocher, Berthold, Knip, Mikael, Saw, Seang-Mei, Holloway, John W., Melén, Erik, Grant, Struan F.A., Feenstra, Bjarke, Lowe, William L., Widén, Elisabeth, Sergeyev, Elena, Grallert, Harald, Custovic, Adnan, Jacobsson, Bo, Jarvelin, Marjo-Riitta, Atalay, Mustafa, Koppelman, Gerard H., Pennell, Craig E., Niinikoski, Harri, Dedoussis, George V., Mccarthy, Mark I., Frayling, Timothy M., Sunyer, Jordi, Timpson, Nicholas J., Rivadeneira, Fernando, Bønnelykke, Klaus, Jaddoe, Vincent W.V.
Publicado 2015

Rare genetic variants in the CFI gene are associated with advanced age-related macular degeneration and commonly result in reduced serum factor I levels

por Kavanagh, David, Yu, Yi, Schramm, Elizabeth C., Triebwasser, Michael, Wagner, Erin K., Raychaudhuri, Soumya, Daly, Mark J., Atkinson, John P., Seddon, Johanna M.
Publicado 2015

A common variant near TGFBR3 is associated with primary open angle glaucoma

por Li, Zheng, Allingham, R. Rand, Nakano, Masakazu, Jia, Liyun, Chen, Yuhong, Ikeda, Yoko, Mani, Baskaran, Chen, Li-Jia, Kee, Changwon, Garway-Heath, David F., Sripriya, Sarangapani, Fuse, Nobuo, Abu-Amero, Khaled K., Huang, Chukai, Namburi, Prasanthi, Burdon, Kathryn, Perera, Shamira A., Gharahkhani, Puya, Lin, Ying, Ueno, Morio, Ozaki, Mineo, Mizoguchi, Takanori, Krishnadas, Subbiah Ramasamy, Osman, Essam A., Lee, Mei Chin, Chan, Anita S.Y., Tajudin, Liza-Sharmini A., Do, Tan, Goncalves, Aurelien, Reynier, Pascal, Zhang, Hong, Bourne, Rupert, Goh, David, Broadway, David, Husain, Rahat, Negi, Anil K., Su, Daniel H, Ho, Ching-Lin, Blanco, Augusto Azuara, Leung, Christopher K.S., Wong, Tina T., Yakub, Azhany, Liu, Yutao, Nongpiur, Monisha E., Han, Jong Chul, Hon, Do Nhu, Shantha, Balekudaru, Zhao, Bowen, Sang, Jinghong, Zhang, NiHong, Sato, Ryuichi, Yoshii, Kengo, Panda-Jonas, Songhomita, Ashley Koch, Allison E., Herndon, Leon W., Moroi, Sayoko E., Challa, Pratap, Foo, Jia Nee, Bei, Jin-Xin, Zeng, Yi-Xin, Simmons, Cameron P., Bich Chau, Tran Nguyen, Sharmila, Philomenadin Ferdinamarie, Chew, Merwyn, Lim, Blanche, Tam, Pansy O.S., Chua, Elaine, Ng, Xiao Yu, Yong, Victor H.K., Chong, Yaan Fun, Meah, Wee Yang, Vijayan, Saravanan, Seongsoo, Sohn, Xu, Wang, Teo, Yik Ying, Cooke Bailey, Jessica N., Kang, Jae H., Haines, Jonathan L., Cheng, Ching Yu, Saw, Seang-Mei, Tai, E-Shyong, Richards, Julia E., Ritch, Robert, Gaasterland, Douglas E., Pasquale, Louis R., Liu, Jianjun, Jonas, Jost B., Milea, Dan, George, Ronnie, Al-Obeidan, Saleh A., Mori, Kazuhiko, Macgregor, Stuart, Hewitt, Alex W., Girkin, Christopher A., Zhang, Mingzhi, Sundaresan, Periasamy, Vijaya, Lingam, Mackey, David A., Wong, Tien Yin, Craig, Jamie E., Sun, Xinghuai, Kinoshita, Shigeru, Wiggs, Janey L., Khor, Chiea-Chuen, Yang, Zhenglin, Pang, Chi Pui, Wang, Ningli, Hauser, Michael A., Tashiro, Kei, Aung, Tin, Vithana, Eranga N.
Publicado 2015

Genetic variants in adult bone mineral density and fracture risk genes are associated with the rate of bone mineral density acquisition in adolescence

por Warrington, Nicole M., Kemp, John P., Tilling, Kate, Tobias, Jonathan H., Evans, David M.
Publicado 2015

Genomic prediction of complex human traits: relatedness, trait architecture and predictive meta-models

por Spiliopoulou, Athina, Nagy, Reka, Bermingham, Mairead L., Huffman, Jennifer E., Hayward, Caroline, Vitart, Veronique, Rudan, Igor, Campbell, Harry, Wright, Alan F., Wilson, James F., Pong-Wong, Ricardo, Agakov, Felix, Navarro, Pau, Haley, Chris S.
Publicado 2015

Gene × dietary pattern interactions in obesity: analysis of up to 68 317 adults of European ancestry

por Nettleton, Jennifer A., Follis, Jack L., Ngwa, Julius S., Smith, Caren E., Ahmad, Shafqat, Tanaka, Toshiko, Wojczynski, Mary K., Voortman, Trudy, Lemaitre, Rozenn N., Kristiansson, Kati, Nuotio, Marja-Liisa, Houston, Denise K., Perälä, Mia-Maria, Qi, Qibin, Sonestedt, Emily, Manichaikul, Ani, Kanoni, Stavroula, Ganna, Andrea, Mikkilä, Vera, North, Kari E., Siscovick, David S., Harald, Kennet, Mckeown, Nicola M., Johansson, Ingegerd, Rissanen, Harri, Liu, Yongmei, Lahti, Jari, Hu, Frank B., Bandinelli, Stefania, Rukh, Gull, Rich, Stephen, Booij, Lisanne, Dmitriou, Maria, Ax, Erika, Raitakari, Olli, Mukamal, Kenneth, Männistö, Satu, Hallmans, Göran, Jula, Antti, Ericson, Ulrika, Jacobs,, David R., Van Rooij, Frank J. A., Deloukas, Panos, Sjögren, Per, Kähönen, Mika, Djousse, Luc, Perola, Markus, Barroso, Inês, Hofman, Albert, Stirrups, Kathleen, Viikari, Jorma, Uitterlinden, André G., Kalafati, Ioanna P., Franco, Oscar H., Mozaffarian, Dariush, Salomaa, Veikko, Borecki, Ingrid B., Knekt, Paul, Kritchevsky, Stephen B., Eriksson, Johan G., Dedoussis, George V., Qi, Lu, Ferrucci, Luigi, Orho-Melander, Marju, Zillikens, M. Carola, Ingelsson, Erik, Lehtimäki, Terho, Renström, Frida, Cupples, L. Adrienne, Loos, Ruth J. F., Franks, Paul W.
Publicado 2015

Genome-wide association study of toxic metals and trace elements reveals novel associations

por Ng, Esther, Lind, P. Monica, Lindgren, Cecilia, Ingelsson, Erik, Mahajan, Anubha, Morris, Andrew, Lind, Lars
Publicado 2015

Dissecting the genetics of the human transcriptome identifies novel trait-related trans-eQTLs and corroborates the regulatory relevance of non-protein coding loci(†)

por Kirsten, Holger, Al-Hasani, Hoor, Holdt, Lesca, Gross, Arnd, Beutner, Frank, Krohn, Knut, Horn, Katrin, Ahnert, Peter, Burkhardt, Ralph, Reiche, Kristin, Hackermüller, Jörg, Löffler, Markus, Teupser, Daniel, Thiery, Joachim, Scholz, Markus
Publicado 2015

Genetic determinants of telomere length and risk of common cancers: a Mendelian randomization study

por Zhang, Chenan, Doherty, Jennifer A., Burgess, Stephen, Hung, Rayjean J., Lindström, Sara, Kraft, Peter, Gong, Jian, Amos, Christopher I., Sellers, Thomas A., Monteiro, Alvaro N.A., Chenevix-Trench, Georgia, Bickeböller, Heike, Risch, Angela, Brennan, Paul, Mckay, James D., Houlston, Richard S., Landi, Maria Teresa, Timofeeva, Maria N., Wang, Yufei, Heinrich, Joachim, Kote-Jarai, Zsofia, Eeles, Rosalind A., Muir, Ken, Wiklund, Fredrik, Grönberg, Henrik, Berndt, Sonja I., Chanock, Stephen J., Schumacher, Fredrick, Haiman, Christopher A., Henderson, Brian E., Amin Al Olama, Ali, Andrulis, Irene L., Hopper, John L., Chang-Claude, Jenny, John, Esther M., Malone, Kathleen E., Gammon, Marilie D., Ursin, Giske, Whittemore, Alice S., Hunter, David J., Gruber, Stephen B., Knight, Julia A., Hou, Lifang, Le Marchand, Loic, Newcomb, Polly A., Hudson, Thomas J., Chan, Andrew T., Li, Li, Woods, Michael O., Ahsan, Habibul, Pierce, Brandon L.
Publicado 2015

Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans

por Amin Al Olama, Ali, Dadaev, Tokhir, Hazelett, Dennis J., Li, Qiuyan, Leongamornlert, Daniel, Saunders, Edward J., Stephens, Sarah, Cieza-Borrella, Clara, Whitmore, Ian, Benlloch Garcia, Sara, Giles, Graham G., Southey, Melissa C., Fitzgerald, Liesel, Gronberg, Henrik, Wiklund, Fredrik, Aly, Markus, Henderson, Brian E., Schumacher, Fredrick, Haiman, Christopher A., Schleutker, Johanna, Wahlfors, Tiina, Tammela, Teuvo L., Nordestgaard, Børge G., Key, Tim J., Travis, Ruth C., Neal, David E., Donovan, Jenny L., Hamdy, Freddie C., Pharoah, Paul, Pashayan, Nora, Khaw, Kay-Tee, Stanford, Janet L., Thibodeau, Stephen N., Mcdonnell, Shannon K., Schaid, Daniel J., Maier, Christiane, Vogel, Walther, Luedeke, Manuel, Herkommer, Kathleen, Kibel, Adam S., Cybulski, Cezary, Wokołorczyk, Dominika, Kluzniak, Wojciech, Cannon-Albright, Lisa, Brenner, Hermann, Butterbach, Katja, Arndt, Volker, Park, Jong Y., Sellers, Thomas, Lin, Hui-Yi, Slavov, Chavdar, Kaneva, Radka, Mitev, Vanio, Batra, Jyotsna, Clements, Judith A., Spurdle, Amanda, Teixeira, Manuel R., Paulo, Paula, Maia, Sofia, Pandha, Hardev, Michael, Agnieszka, Kierzek, Andrzej, Govindasami, Koveela, Guy, Michelle, Lophatonanon, Artitaya, Muir, Kenneth, Viñuela, Ana, Brown, Andrew A., Freedman, Mathew, Conti, David V., Easton, Douglas, Coetzee, Gerhard A., Eeles, Rosalind A., Kote-Jarai, Zsofia
Publicado 2015

Genome-wide association analysis on normal hearing function identifies PCDH20 and SLC28A3 as candidates for hearing function and loss

por Vuckovic, Dragana, Dawson, Sally, Scheffer, Deborah I., Rantanen, Taina, Morgan, Anna, Di Stazio, Mariateresa, Vozzi, Diego, Nutile, Teresa, Concas, Maria P., Biino, Ginevra, Nolan, Lisa, Bahl, Aileen, Loukola, Anu, Viljanen, Anne, Davis, Adrian, Ciullo, Marina, Corey, David P., Pirastu, Mario, Gasparini, Paolo, Girotto, Giorgia
Publicado 2015

Genome-wide enrichment analysis between endometriosis and obesity-related traits reveals novel susceptibility loci

por Rahmioglu, Nilufer, Macgregor, Stuart, Drong, Alexander W., Hedman, Åsa K., Harris, Holly R., Randall, Joshua C., Prokopenko, Inga, Nyholt, Dale R., Morris, Andrew P., Montgomery, Grant W., Missmer, Stacey A., Lindgren, Cecilia M., Zondervan, Krina T.
Publicado 2015

Genome-wide association study identifies SNPs in the MHC class II loci that are associated with self-reported history of whooping cough

por McMahon, George, Ring, Susan M., Davey-Smith, George, Timpson, Nicholas J.
Publicado 2015

Multiple breast cancer risk variants are associated with differential transcript isoform expression in tumors

por Caswell, Jennifer L., Camarda, Roman, Zhou, Alicia Y., Huntsman, Scott, Hu, Donglei, Brenner, Steven E., Zaitlen, Noah, Goga, Andrei, Ziv, Elad
Publicado 2015

Methylation quantitative trait locus analysis of osteoarthritis links epigenetics with genetic risk

por Rushton, Michael D., Reynard, Louise N., Young, David A., Shepherd, Colin, Aubourg, Guillaume, Gee, Fiona, Darlay, Rebecca, Deehan, David, Cordell, Heather J., Loughlin, John
Publicado 2015

Prenatal and early life influences on epigenetic age in children: a study of mother–offspring pairs from two cohort studies

por Simpkin, Andrew J., Hemani, Gibran, Suderman, Matthew, Gaunt, Tom R., Lyttleton, Oliver, Mcardle, Wendy L., Ring, Susan M., Sharp, Gemma C., Tilling, Kate, Horvath, Steve, Kunze, Sonja, Peters, Annette, Waldenberger, Melanie, Ward-Caviness, Cavin, Nohr, Ellen A., Sørensen, Thorkild I. A., Relton, Caroline L., Smith, George Davey
Publicado 2016

Genome-wide association study identifies common and low-frequency variants at the AMH gene locus that strongly predict serum AMH levels in males

por Perry, John R.B., McMahon, George, Day, Felix R., Ring, Susan M, Nelson, Scott M., Lawlor, Debbie A.
Publicado 2016

Chronic gastroesophageal reflux disease shares genetic background with esophageal adenocarcinoma and Barrett's esophagus

por Gharahkhani, Puya, Tung, Joyce, Hinds, David, Mishra, Aniket, Vaughan, Thomas L., Whiteman, David C., MacGregor, Stuart
Publicado 2016