“…CCK8, EdU, clone formation, and senescence-associated β-galactosidase (SA-β-gal) staining assays were performed to assess cell proliferation and cellular senescence phenotypes. …”
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“…A ChIP assay was performed to assess the interaction of the transcription factor YB-1 and associated DNA regions. A double fluorescein reporter gene assay was designed to assess the influence of WT/S102A/S102E YB-1 on the promoter region of PARP1. …”
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“…The active principle is associated with a nucleo-proteid in the extract and may be separated with this nucleo-proteid from the remaining inert albuminous substances. …”
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“…Unless the subcutis of the guinea-pig reacts to toxin-antitoxin mixtures in a manner peculiar to itself, a practical, easily controlled method for active immunization can be worked out which should afford a larger protection than the serum alone and avoid the complications associated with horse serum. That proportion of toxin and antitoxin which would produce the highest desirable immunity consistent with the least discomfort would have to be carefully worked out for the human subject. …”
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“…The development of the constrictor substance, or property, is associated with changes undergone probably by formed elements of the blood when it is shed. …”
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“…With the establishment of a state of anuria in these control animals the hydrogen ion content of the blood has increased, the alkali reserve of the blood has been rapidly depleted, and associated with this change the carbon dioxide tension has been reduced. …”
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“…In its natural habitat, or the crystalline style, it is usually pure, but is sometimes found in association with a tiny spiral organism (Spirillum ostreæ). …”
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“…The peculiar difficulties encountered in filtering herpes virus particularly suggest a source of error of this kind, and if we are right in assuming the intracellular position of this virus in the nervous tissue, it is more than likely that most of the virus obtained in suspension may be closely associated with protein particles derived from the cells. …”
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“…Investigation of bacterial properties associated with virulence has as yet given no definite and positive results.…”
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“…The comparatively high rates of oxygen consumption by the inhibited (unfertilized) eggs of Chaetopterus and Cumingia are not directly associated with nuclear or morphological activity of the cell since they continue at the high rate for hours after cessation of the brief initial nuclear activity, which takes place when the eggs are placed in sea water. 9. …”
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“…The studies of Clark and Ruehl (16), Henrici (17), Bayne-Jones and Adolph (18) and others have demonstrated a marked increase in the size of the bacterial cell associated with the early phases of growth. These authors have dealt chiefly with noncapsulated rod forms and even Clark and Ruehl who included cultures of various cocci do not make reference to variations in capsule size. …”
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“…In conclusion, dose escalation from 64 to 74 Gy using conformal radiotherapy may improve long-term PSA control, but a treatment margin of 1.5 cm is unnecessary and is associated with increased acute bowel and bladder reactions and more late rectal side effects. …”
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“…A clear antagonist, additive or synergic effect of nonsteroidal anti–inflammatory drugs (NSAIDs)–cannabinoid associations was not yet demonstrated. Aim. The present study tried to summarize the existent data on NSAIDS-cannabinoid system interactions. …”
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“…What is the toxicity associated with the use of bortezomib? 3. Which patients are more or less likely to benefit from treatment with bortezomib? …”
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“…Recently researchers have used underwater visual surveys, primarily of limited spatial extent or nonstandard design, to infer negative associations between reef shark abundance and human populations. …”
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“…L'agent causal a été staphylococcus épdermidis dans 5 cas, colibacille dans 2 cas et association staphylococcus-BGN dans 1 cas. Les différentes modalités que nous avons utilisé pour traiter l'infection dans notre ont été un lavage simple, système d'irrigation-drainage et réimplantation simple en un seul temps ou en 2 temps avec couverture systématique par une antibiothérapie adaptée selon l'antibiogramme. …”
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“…HER2 mRNA expression was significantly associated with pCR in the HER2-positive/ESR1-positive tumors (P = 0.004), but not in HER2-positive/ESR1-negative tumors. …”
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“…The pre-genomic era was a time when toxicologic pathologists played a major role in drug development, evaluating the cancer bioassay and the associated dose-setting toxicity studies, and exploring the utility of proposed alternative animal models. …”
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“…HES was significantly associated with more adverse events (5.3% versus 2.8%; P <0.001). …”
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“…The objective of this study was to investigate if unblinding in randomized controlled trials (RCTs) is associated with enhanced placebo effects for intervention groups and nocebo effects for placebo groups. …”
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