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1721por Rostamian, Somayeh, van Buchem, Mark A., Jukema, J. Wouter, Gussekloo, Jacobijn, Poortvliet, Rosalinde K. E., de Cren, Anton J. M., Sabayan, Behnam“…Similarly, each point lower performance in “orientation to place” was significantly associated with higher risk of first-time myocardial infarction (HR 1.67, 95% CI 1.25–2.22, P = 0.001), first-time stroke (HR 1.39, 95% CI 1.05–1.82, P = 0.016), cardiovascular mortality (HR 1.35, 95% CI 1.00–1.82, P = 0.054) and non-cardiovascular mortality (HR 1.45, 95% CI 1.20–1.77, P < 0.001). …”
Publicado 2017
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1722por Laviola, Giovanni, Zoratto, Francesca, Ingiosi, Danilo, Carito, Valentina, Huzard, Damien, Fiore, Marco, Macrì, SimoneEnlace del recurso
Publicado 2017
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1723por Qiu, Chengfeng, Zhou, Quan, Li, Xiaohui, Zhang, Zhen, Zeng, Pingyu, Cao, Zeng, Pan, Bingjie, Li, Xiaogang, Chen, Alex F.“…Whether the baseline circulating proprotein convertase subtilisin/Kexin type 9 (PCSK9) concentration associates with cardiovascular risk remains uncertain. …”
Publicado 2017
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1724por Damodaran, Shivashankar, Damaschke, Nathan, Gawdzik, Joseph, Yang, Bing, Shi, Cedric, Allen, Glenn O., Huang, Wei, Denu, John, Jarrard, David“…Acetylation of histone H3K18, associated with gene activation, is enhanced by P300 and opposed by the deacetylase Sirtuin2 (SIRT2). …”
Publicado 2017
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1725por Yue, Yanan, Liu, Jun, Cui, Xiaolong, Cao, Jie, Luo, Guanzheng, Zhang, Zezhou, Cheng, Tao, Gao, Minsong, Shu, Xiao, Ma, Honghui, Wang, Fengqin, Wang, Xinxia, Shen, Bin, Wang, Yizhen, Feng, Xinhua, He, Chuan, Liu, Jianzhao“…Depletions of VIRMA and METTL3 induce 3′UTR lengthening of several hundred mRNAs with over 50% targets in common. VIRMA associates with polyadenylation cleavage factors CPSF5 and CPSF6 in an RNA-dependent manner. …”
Publicado 2018
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1726por Sharma, Sandeep, Sahu, Ranabir, Navathe, Sudhir, Mishra, Vinod K., Chand, Ramesh, Singh, Pawan K., Joshi, Arun K., Pandey, Shree P.Enlace del recurso
Publicado 2018
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1727por Gupta, Ankit, Balabaskaran-Nina, Praveen, Nguitragool, Wang, Saggu, Gagandeep S., Schureck, Marc A., Desai, Sanjay A.Enlace del recurso
Publicado 2018
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1728“…OBJECTIVE: To determine the cost-effectiveness of Gynaecology Teaching Associate (GTA) teaching versus conventional pelvic model (manikin) teaching of pelvic examination skills for final year medical students within a UK undergraduate obstetrics and gynaecology (O&G) curriculum. …”
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1729por Poletaeva, Julia, Dovydenko, Ilya, Epanchintseva, Anna, Korchagina, Kseniya, Pyshnyi, Dmitrii, Apartsin, Evgeny, Ryabchikova, Elena, Pyshnaya, Inna“…Formation of cores was confirmed using gel electrophoresis. Stable associates were prepared, and then enveloped into a lipid layer composed of phosphatidylcholine, phosphatidylethanolamine and novel pH-sensitive lipidoid. …”
Publicado 2018
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1730por Ranti, Juha, Kurki, Samu, Salmenniemi, Urpu, Putkonen, Mervi, Salomäki, Soile, Itälä-Remes, Maija“…Multivariate analysis showed that slow CD8(+) T-cell reconstitution was strongly associated with increased risk of relapse (HR = 3.44, P = 0.026). …”
Publicado 2018
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1731“…The preliminary findings presented detail a transcriptomic signature associated with response to multiple checkpoint inhibitors and suggest novel biological associations that warrant further investigation.…”
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1732por Brzezinski, Rafael Y., Fisher, Eyal, Cohen, Noa, Zwang, Etti, Shefer, Gabi, Stern, Naftali, Zeltser, David, Shapira, Itzhak, Berliner, Shlomo, Rogowski, Ori, Shenhar-Tsarfaty, Shani“…BACKGROUND: Imbalanced autonomic nervous system (ANS) activity is associated with poor cardiovascular outcome. However, clinically validated biomarkers to assess parasympathetic function are not yet available. …”
Publicado 2018
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1733por Huang, Suli, Lv, Ziquan, Wen, Ying, Wei, Yazhen, Zhou, Li, Ke, Yuebin, Zhang, Yanwei, Xu, Qianhui, Li, Lu, Guo, Yinsheng, Li, Di, Xie, Changhui, Guo, Yi, Cheng, Jinquan“…The blood level of miR‐129‐2‐3p was significantly lower in IS patients (P < 0.05), and negatively associated with the risk of IS (adjusted OR: 0.88; 95% CI: 0.80‐0.98; P = 0.021) by multivariable logistic regression analysis. …”
Publicado 2018
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1734“…Further studies revealed that NAF1 was transcriptionally regulated by c-Myc, NRF2, and telomerase reverse transcriptase (TERT), which are the key molecules associated with malignant progression of gliomas. Moreover, we demonstrated that NAF1 was a functional oncogene in glioma cells through promoting cell growth in vitro and in vivo, survival, migration, and invasion. …”
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1735por Cuyàs, Elisabet, Buxó, Maria, Ferri Iglesias, Maria José, Verdura, Sara, Pernas, Sonia, Dorca, Joan, Álvarez, Isabel, Martínez, Susana, Pérez-Garcia, Jose Manuel, Batista-López, Norberto, Rodríguez-Sánchez, César A., Amillano, Kepa, Domínguez, Severina, Luque, Maria, Morilla, Idoia, Stradella, Agostina, Viñas, Gemma, Cortés, Javier, Joven, Jorge, Brunet, Joan, López-Bonet, Eugeni, Garcia, Margarita, Saidani, Samiha, Queralt Moles, Xavier, Martin-Castillo, Begoña, Menendez, Javier A.“…Background: The minor allele (C) of the single-nucleotide polymorphism (SNP) rs11212617, located near the ataxia telangiectasia mutated (ATM) gene, has been associated with an increased likelihood of treatment success with metformin in type 2 diabetes. …”
Publicado 2019
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1736por Daws, Michael R., Nakken, Britt, Lobato-Pascual, Ana, Josien, Régis, Dissen, Erik, Fossum, Sigbjørn“…This association allowed efficient phagocytosis of antibody-coated beads. …”
Publicado 2019
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1737por Davies, Richard, Hammenfors, Daniel, Bergum, Brith, Vogelsang, Petra, Gavasso, Sonia, Brun, Johan G., Jonsson, Roland, Appel, Silke“…Increases in pSTAT1 Y701 were associated with the presence of autoantibodies. Our results indicate involvement of both STAT3 S727 and STAT1 Y701 pathways in pSS patients. …”
Publicado 2018
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1738por Kaida, Angela, Carter, Allison, Nicholson, Valerie, Lemay, Jo, O’Brien, Nadia, Greene, Saara, Tharao, Wangari, Proulx-Boucher, Karène, Gormley, Rebecca, Benoit, Anita, Bernier, Mélina, Thomas-Pavanel, Jamie, Lewis, Johanna, de Pokomandy, Alexandra, Loutfy, Mona“…METHODS: Through our work on the Canadian HIV Women’s Sexual and Reproductive Health Cohort Study (CHIWOS), Canada’s largest community-collaborative longitudinal cohort of women living with HIV (n = 1422), we developed a comprehensive, regionally tailored approach for hiring, training, and supporting women living with HIV as Peer Research Associates (PRAs). To reflect the diversity of women with HIV in Canada, we initially hired 37 PRAs from British Columbia, Ontario, and Quebec, prioritizing women historically under-represented in research, including women who use or have used illicit drugs, and women living with HIV of other social identities including Indigenous, racialized, LGBTQ2S, and sex work communities, noting important points of intersection between these groups. …”
Publicado 2019
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1739“…Here, to explore the trafficking mechanism of LeEIX2-mediated immune signaling, we used a proteomic approach to identify LeEIX2-associating proteins. We report the identification of SlDRP2A, a dynamin related protein, as an associating partner for LeEIX2. …”
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1740por Michalik, Katarzyna, Szklarzewicz, Teresa, Kalandyk-Kołodziejczyk, Małgorzata, Michalik, Anna“…In contrast to most plant sap-sucking hemipterans, the bacterial associates of O. urticae, M. pini, and S. gorodetskia are not harbored in specialized bacteriocytes, but are dispersed in the cells of different organs. …”
Publicado 2019
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