Activation of Liver AMPK with PF-06409577 Corrects NAFLD and Lowers Cholesterol in Rodent and Primate Preclinical Models

por Esquejo, Ryan M., Salatto, Christopher T., Delmore, Jake, Albuquerque, Bina, Reyes, Allan, Shi, Yuji, Moccia, Rob, Cokorinos, Emily, Peloquin, Matthew, Monetti, Mara, Barricklow, Jason, Bollinger, Eliza, Smith, Brennan K., Day, Emily A., Nguyen, Chuong, Geoghegan, Kieran F., Kreeger, John M., Opsahl, Alan, Ward, Jessica, Kalgutkar, Amit S., Tess, David, Butler, Lynne, Shirai, Norimitsu, Osborne, Timothy F., Steinberg, Gregory R., Birnbaum, Morris J., Cameron, Kimberly O., Miller, Russell A.
Publicado 2018

Artificial Intelligence-Assisted Loop Mediated Isothermal Amplification (AI-LAMP) for Rapid Detection of SARS-CoV-2

por Rohaim, Mohammed A., Clayton, Emily, Sahin, Irem, Vilela, Julianne, Khalifa, Manar E., Al-Natour, Mohammad Q., Bayoumi, Mahmoud, Poirier, Aurore C., Branavan, Manoharanehru, Tharmakulasingam, Mukunthan, Chaudhry, Nouman S., Sodi, Ravinder, Brown, Amy, Burkhart, Peter, Hacking, Wendy, Botham, Judy, Boyce, Joe, Wilkinson, Hayley, Williams, Craig, Whittingham-Dowd, Jayde, Shaw, Elisabeth, Hodges, Matt, Butler, Lisa, Bates, Michelle D., La Ragione, Roberto, Balachandran, Wamadeva, Fernando, Anil, Munir, Muhammad
Publicado 2020

Shwachman–Bodian–Diamond syndrome (SBDS) protein is a direct inhibitor of protein phosphatase 2A (PP2A) activity and overexpressed in acute myeloid leukaemia

por Dun, Matthew D., Mannan, Abdul, Rigby, Callum J., Butler, Stephen, Toop, Hamish D., Beck, Dominik, Connerty, Patrick, Sillar, Jonathan, Kahl, Richard G. S., Duchatel, Ryan J., Germon, Zacary, Faulkner, Sam, Chi, Mengna, Skerrett-Byrne, David, Murray, Heather C., Flanagan, Hayley, Almazi, Juhura G., Hondermarck, Hubert, Nixon, Brett, De Iuliis, Geoff, Chamberlain, Janis, Alvaro, Frank, de Bock, Charles E., Morris, Jonathan C., Enjeti, Anoop K., Verrills, Nicole M.
Publicado 2020

Influenza and Respiratory Virus Surveillance, Vaccine Uptake, and Effectiveness at a Time of Cocirculating COVID-19: Protocol for the English Primary Care Sentinel System for 2020-...

por de Lusignan, Simon, Lopez Bernal, Jamie, Byford, Rachel, Amirthalingam, Gayatri, Ferreira, Filipa, Akinyemi, Oluwafunmi, Andrews, Nick, Campbell, Helen, Dabrera, Gavin, Deeks, Alexandra, Elliot, Alex J, Krajenbrink, Else, Liyanage, Harshana, McGagh, Dylan, Okusi, Cecilia, Parimalanathan, Vaishnavi, Ramsay, Mary, Smith, Gillian, Tripathy, Manasa, Williams, John, Victor, William, Zambon, Maria, Howsam, Gary, Nicholson, Brian David, Tzortziou Brown, Victoria, Butler, Christopher C, Joy, Mark, Hobbs, FD Richard
Publicado 2021

‘An Apple a Day’?: Psychiatrists, Psychologists and Psychotherapists Report Poor Literacy for Nutritional Medicine: International Survey Spanning 52 Countries

por Mörkl, Sabrina, Stell, Linda, Buhai, Diana V., Schweinzer, Melanie, Wagner-Skacel, Jolana, Vajda, Christian, Lackner, Sonja, Bengesser, Susanne A., Lahousen, Theresa, Painold, Annamaria, Oberascher, Andreas, Tatschl, Josef M., Fellinger, Matthäus, Müller-Stierlin, Annabel, Serban, Ana C., Ben-Sheetrit, Joseph, Vejnovic, Ana-Marija, Butler, Mary I., Balanzá-Martínez, Vicent, Zaja, Nikola, Rus-Prelog, Polona, Strumila, Robertas, Teasdale, Scott B., Reininghaus, Eva Z., Holasek, Sandra J.
Publicado 2021

Platform Randomised trial of INterventions against COVID-19 In older peoPLE (PRINCIPLE): protocol for a randomised, controlled, open-label, adaptive platform, trial of community tr...

por Hayward, Gail, Butler, Christopher C, Yu, Ly-Mee, Saville, Benjamin R, Berry, Nicholas, Dorward, Jienchi, Gbinigie, Oghenekome, van Hecke, Oliver, Ogburn, Emma, Swayze, Hannah, Bongard, Emily, Allen, Julie, Tonner, Sharon, Rutter, Heather, Tonkin-Crine, Sarah, Borek, Aleksandra, Judge, David, Grabey, Jenna, de Lusignan, Simon, Thomas, Nicholas P B, Evans, Philip H, Andersson, Monique I, Llewelyn, Martin, Patel, Mahendra, Hopkins, Susan, Hobbs, F D Richard
Publicado 2021

Adjuvant nivolumab for stage III/IV melanoma: evaluation of safety outcomes and association with recurrence-free survival

por Mandalá, Mario, Larkin, James, Ascierto, Paolo A, Del Vecchio, Michele, Gogas, Helen, Cowey, C Lance, Arance, Ana, Dalle, Stéphane, Schenker, Michael, Grob, Jean-Jacques, Chiarion-Sileni, Vanna, Marquez-Rodas, Ivan, Butler, Marcus O, Di Giacomo, Anna Maria, Lutzky, Jose, De La Cruz-Merino, Luis, Atkinson, Victoria, Arenberger, Petr, Hill, Andrew, Fecher, Leslie, Millward, Michael, Khushalani, Nikhil I, de Pril, Veerle, Lobo, Maurice, Weber, Jeffrey
Publicado 2021

RetINal Toxicity And HydroxyChloroquine Therapy (INTACT): protocol for a prospective population-based cohort study

por Daftarian, Narsis, Lima, Adriana, Marozoff, Shelby, Ojo, Dami, Levasseur, Steve D, Maberley, David A L, Hoens, Alison, Esdaile, John, Dawes, Martin, Aviña-Zubieta, J Antonio, Adante, Beatrice, Bhui, Ravinder Dennis, Bhui, Suruchi B, Butler, Michael, Chui, Lica, Erasmus, Murray, Etminan, Mahyar, Godinho, Derek, Hay, Elizabeth, Hollands, Hussein, Hoonjan, Malvinder, Joe, Aaron, Lukaris, Andrew, Mammo, Zaid, Navajas, Eduardo, Pakzad-Vaezi, Kaivon, Sanmugasunderam, Suren, Shojania, Kam
Publicado 2022

Combined impact of lipidomic and genetic aberrations on clinical outcomes in metastatic castration-resistant prostate cancer

por Mak, Blossom, Lin, Hui-Ming, Kwan, Edmond M., Fettke, Heidi, Tran, Ben, Davis, Ian D., Mahon, Kate, Stockler, Martin R., Briscoe, Karen, Marx, Gavin, Zhang, Alison, Crumbaker, Megan, Tan, Winston, Huynh, Kevin, Meikle, Thomas G., Mellett, Natalie A., Hoy, Andrew J., Du, Pan, Yu, Jianjun, Jia, Shidong, Joshua, Anthony M., Waugh, David J., Butler, Lisa M., Kohli, Manish, Meikle, Peter J., Azad, Arun A., Horvath, Lisa G.
Publicado 2022

Differential Immune Checkpoint and Ig-like V-Type Receptor Profiles in COVID-19: Associations with Severity and Treatment

por Lozano-Rodríguez, Roberto, Terrón-Arcos, Verónica, López, Raúl, Martín-Gutiérrez, Juan, Martín-Quirós, Alejandro, Maroun-Eid, Charbel, del Val, Elena Muñoz, Cañada-Illana, Carlos, Pascual Iglesias, Alejandro, Quiroga, Jaime Valentín, Montalbán-Hernández, Karla, Casalvilla-Dueñas, José Carlos, García-Garrido, Miguel A., del Balzo-Castillo, Álvaro, Peinado-Quesada, María A., Gómez-Lage, Laura, Herrero-Benito, Carmen, G. Butler, Ray, Avendaño-Ortiz, José, López-Collazo, Eduardo
Publicado 2022

Low-dose trimethoprim-sulfamethoxazole for the treatment of Pneumocystis jirovecii pneumonia (LOW-TMP): protocol for a phase III randomised, placebo-controlled, dose-comparison tri...

por Sohani, Zahra N., Butler-Laporte, Guillaume, Aw, Andrew, Belga, Sara, Benedetti, Andrea, Carignan, Alex, Cheng, Matthew P., Coburn, Bryan, Costiniuk, Cecilia T, Ezer, Nicole, Gregson, Dan, Johnson, Andrew, Khwaja, Kosar, Lawandi, Alexander, Leung, Victor, Lother, Sylvain, MacFadden, Derek, McGuinty, Michaeline, Parkes, Leighanne, Qureshi, Salman, Roy, Valerie, Rush, Barret, Schwartz, Ilan, So, Miranda, Somayaji, Ranjani, Tan, Darrell, Trinh, Emilie, Lee, Todd C., McDonald, Emily G.
Publicado 2022

Unified classification and risk-stratification in Acute Myeloid Leukemia

por Tazi, Yanis, Arango-Ossa, Juan E., Zhou, Yangyu, Bernard, Elsa, Thomas, Ian, Gilkes, Amanda, Freeman, Sylvie, Pradat, Yoann, Johnson, Sean J., Hills, Robert, Dillon, Richard, Levine, Max F., Leongamornlert, Daniel, Butler, Adam, Ganser, Arnold, Bullinger, Lars, Döhner, Konstanze, Ottmann, Oliver, Adams, Richard, Döhner, Hartmut, Campbell, Peter J., Burnett, Alan K., Dennis, Michael, Russell, Nigel H., Devlin, Sean M., Huntly, Brian J. P., Papaemmanuil, Elli
Publicado 2022

A Novel Role for DNA-PK in Metabolism by Regulating Glycolysis in Castration-Resistant Prostate Cancer

por Dylgjeri, Emanuela, Kothari, Vishal, Shafi, Ayesha A., Semenova, Galina, Gallagher, Peter T., Guan, Yi F., Pang, Angel, Goodwin, Jonathan F., Irani, Swati, McCann, Jennifer J., Mandigo, Amy C., Chand, Saswati, McNair, Christopher M., Vasilevskaya, Irina, Schiewer, Matthew J., Lallas, Costas D., McCue, Peter A., Gomella, Leonard G., Seifert, Erin L., Carroll, Jason S., Butler, Lisa M., Holst, Jeff, Kelly, William K., Knudsen, Karen E.
Publicado 2022

Clonal diversification and histogenesis of malignant germ cell tumours

por Oliver, Thomas R. W., Chappell, Lia, Sanghvi, Rashesh, Deighton, Lauren, Ansari-Pour, Naser, Dentro, Stefan C., Young, Matthew D., Coorens, Tim H. H., Jung, Hyunchul, Butler, Tim, Neville, Matthew D. C., Leongamornlert, Daniel, Sanders, Mathijs A., Hooks, Yvette, Cagan, Alex, Mitchell, Thomas J., Cortes-Ciriano, Isidro, Warren, Anne Y., Wedge, David C., Heer, Rakesh, Coleman, Nicholas, Murray, Matthew J., Campbell, Peter J., Rahbari, Raheleh, Behjati, Sam
Publicado 2022

The architecture of clonal expansions in morphologically normal tissue from cancerous and non-cancerous prostates

por Buhigas, Claudia, Warren, Anne Y., Leung, Wing-Kit, Whitaker, Hayley C., Luxton, Hayley J., Hawkins, Steve, Kay, Jonathan, Butler, Adam, Xu, Yaobo, Woodcock, Dan J., Merson, Sue, Frame, Fiona M., Sahli, Atef, Abascal, Federico, Martincorena, Iñigo, Bova, G. Steven, Foster, Christopher S., Campbell, Peter, Maitland, Norman J., Neal, David E., Massie, Charlie E., Lynch, Andy G., Eeles, Rosalind A., Cooper, Colin S., Wedge, David C., Brewer, Daniel S.
Publicado 2022

Monkeypox Case Investigation — Cook County Jail, Chicago, Illinois, July–August 2022

por Hagan, Liesl M., Beeson, Amy, Hughes, Sarah, Hassan, Rashida, Tietje, Lauren, Meehan, Ashley A., Spencer, Hillary, Turner, Janice, Richardson, Morgan, Howard, Jourdan, Schultz, Anne, Ali, Salma, Butler, Margaret Mary, Arce Garza, Diana, Morgan, Clint N., Kling, Chantal, Baird, Nicolle, Townsend, Michael B., Carson, William C., Lowe, David, Wynn, Nhien T., Black, Stephanie R., Kerins, Janna L., Rafinski, Josh, Defuniak, Andrew, Auguston, Priscilla, Mosites, Emily, Ghinai, Isaac, Zawitz, Chad
Publicado 2022

Staff perspectives on barriers and enablers to implementing alternative source plasma eligibility criteria for gay, bisexual, and other men who have sex with men

por Castillo, Gisell, Vesnaver, Elisabeth, Gibson, Emily, Butler‐Foster, Terrie, Goldman, Mindy, Hill, Nolan E., Rosser, Andrew, Lapierre, Don, Rubini, Kyle A., MacDonagh, Richard, Miguel, Glenndl, Palumbo, Amelia, MacPherson, Paul, Randall, Taylor, Osbourne‐Sorrell, William, O'Brien, Sheila F., Bridel, William, Otis, Joanne, Greaves, Mark, Al‐Bakri, Taim Bilal, Reid, Marco, Labrecque, Maximilian, Germain, Marc, Orvis, Shane, Clapperton, Andrew T., Devine, Dana, Presseau, Justin
Publicado 2022

Molnupiravir plus usual care versus usual care alone as early treatment for adults with COVID-19 at increased risk of adverse outcomes (PANORAMIC): an open-label, platform-adaptive...

por Butler, Christopher C, Hobbs, F D Richard, Gbinigie, Oghenekome A, Rahman, Najib M, Hayward, Gail, Richards, Duncan B, Dorward, Jienchi, Lowe, David M, Standing, Joseph F, Breuer, Judith, Khoo, Saye, Petrou, Stavros, Hood, Kerenza, Nguyen-Van-Tam, Jonathan S, Patel, Mahendra G, Saville, Benjamin R, Marion, Joe, Ogburn, Emma, Allen, Julie, Rutter, Heather, Francis, Nick, Thomas, Nicholas P B, Evans, Philip, Dobson, Melissa, Madden, Tracie-Ann, Holmes, Jane, Harris, Victoria, Png, May Ee, Lown, Mark, van Hecke, Oliver, Detry, Michelle A, Saunders, Christina T, Fitzgerald, Mark, Berry, Nicholas S, Mwandigha, Lazaro, Galal, Ushma, Mort, Sam, Jani, Bhautesh D, Hart, Nigel D, Ahmed, Haroon, Butler, Daniel, McKenna, Micheal, Chalk, Jem, Lavallee, Layla, Hadley, Elizabeth, Cureton, Lucy, Benysek, Magdalena, Andersson, Monique, Coates, Maria, Barrett, Sarah, Bateman, Clare, Davies, Jennifer C, Raymundo-Wood, Ivy, Ustianowski, Andrew, Carson-Stevens, Andrew, Yu, Ly-Mee, Little, Paul
Publicado 2023

Coulomb excitation of $^{68}_{28}Ni_{40}$ at safe energies

por Bree, N, Stefanescu, I, Butler, P A, Cederkäll, J, Davinson, T, Delahaye, P, Eberth, J, Fedorov, D, Fedosseev, V, Fraile, L M, Franchoo, S, Georgiev, G, Gladnishki, K, Huyse, M, Ivanov, O, Iwanicki, J, Jolie, J, Köster, U, Kröll, T, Krücken, R, Marsh, B A, Niedermaier, O, Reiter, P, Scheit, H, Schwalm, D, Sieber, T, Vande Walle, J, Van Duppen, P, Warr, N, Weisshaar, D, Wenander, F, Zemlyanoy, S, Instituutvoor Kern-en Stralingsfysica, Leuven, K U
Publicado 2008

Coulomb excitation of $^{116}$Te: a study of collectivity above the $Z = 50$ shell gap

por Grahn, T, Pakarinen, J, Wenander, F, Bäck, T, Cederwall, B, Johnson, A, Bree, N, Darby, I G, Diriken,J, Huyse, M, Van Duppen, P, O’Donnell, D, Simpson, J, Julin, R, Rahkila, P, Sandzelius, M, Butler, P A, Gaffney, L P, Grahn, T, Joss, D T, Page, R D, Paul, E S, Scheck, M, Cederkäll, J, Ekström, A, Fahlander, C, Hadinia, B, Smith, J F, Jenkins, D G, Nara Singh, B S, Wadsworth, R
Publicado 2010