“…During a 24-month period were randomly selected 301 patients and a conditional inference tree (CIT) was used as the basis of the prognostic rule. …”
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“…No difference in baseline [(123)I]β-CIT SERT availability was found. The midbrain SERT-to-striatal DAT ratio for whole striatum was significantly lower in patients with PD compared to MSA (P = 0.049). …”
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“…The CS reaction comprises two half-reactions: a Claisen aldol condensation of acetyl-CoA (AcCoA) and oxaloacetate (OAA) that forms citryl-CoA (CitCoA), and CitCoA hydrolysis. Protein conformational changes that ‘close’ the active site play an important role in the assembly of a catalytically competent condensation active site. …”
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“…The severity of 6-OHDA lesions and treatment effects were monitored in vivo using (123)I-FP-CIT (DaTSCAN) SPECT. Quantitative analysis of (123)I-FP-CIT SPECT showed a significant increase of dopamine transporter binding activity in lesioned animals treated with CDNF. …”
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“…Enzymatic conversion of l-Arg to l-Cit derivatives could be monitored by (1)H NMR. …”
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“…Based on their cross-reaction with citrulline-peptides, we designed a novel multi-epitope peptide, containing Cit-Gly and Ala-Cit motifs in two–two copies, separated with a short, neutral spacer. …”
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“…Brain MRI showed enlargement of the ventricles and narrowing of the high convexity cerebrospinal fluid (CSF) spaces with relative dilated Sylvian fissure, the supporting features of NPH. 18F-fluorinated-N-3-fluoropropyl-2-b-carboxymethoxy-3-b-(4-iodophenyl) nortropane ((18)F-FP-CIT) PET showed decreased FP-CIT binding in the left posterior putamen and (18)F-fluorodeoxyglucose PET showed decreased metabolism in the left basal ganglia, consistent with findings of MSA. …”
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“…Pearson Correlation test was used to study correlation of BBPS scores with CIT, gender, BMI, adenoma and polyp detection. RESULTS: In this study 201 patients undergoing colonoscopy were included. …”
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“…By using these antibodies, we detected native LL37 or cit-LL37 in SLE and rheumatoid arthritis (RA) sera, and in LE skin, by ELISA and immunohistochemistry, respectively. …”
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“…Initially, Fluorodeoxyglucose positron emission tomography as well as neuropsychological assessment were suspicious for a possible DLB diagnosis in our patient while core clinical criteria were missing and the indicative biomarker 123I-FP-CIT SPECT was negative. Follow up was performed two years later and the patients showed several core and supportive clinical features of DLB and 123I-FP-CIT SPECT showed a pathological pattern. …”
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“…Finally, patients with anti-cit-HSA were more frequently treated with biologics and combination regimens than patients without these autoantibodies. …”
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“…The electrodes are based on the use of citicolinium/phosphomolybdate [Cit](2)[PM] (sensor I) and citicolinium/tetraphenylborate [Cit][TPB] (sensor II) ion association complexes. …”
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“…The effects of precursor enhancement on crocetin production were investigated by blocking the genes involved in glyoxylate cycle [citric acid synthase (CIT2) and malic acid synthase (MLS1)]. Crocetin titer was promoted by 50% by ΔCIT2 compared to that of the starting strain. …”
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“…Additionally we evaluated (123)I-FP-CIT SPECT binding to striatal dopamine transporter in subjects with clinical manifestations suggestive of Parkinson's Disease and recorded therapeutic management and clinical evolution for 6-months. …”
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“…The research field of cancer immunotherapy (CIT) still faces many challenges in pursuing the broader social goal of “curing cancer.” …”
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“…The most abundant determinant was bla(CIT) and bla(EBC), bla(FOX), and bla(DHA) had the next ranks, respectively. …”
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“…He was treated with induction therapy consisting of 4 cycles of anthracycline-based chemoimmunotherapy (CIT) and 2 cycles of platinum-based CIT with intrathecal methotrexate for CNS prophylaxis followed by continuous maintenance therapy with ibrutinib. …”
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“…In chronic lymphocytic leukemia (CLL), TP53 abnormalities are associated with reduced survival and resistance to chemoimmunotherapy (CIT). The recommended threshold to clinically report TP53 mutations is a matter of debate given that next-generation sequencing technologies can detect mutations with a limit of detection of approximately 1% with high confidence. …”
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“…The study aims to meet R22 requirements based on the EN45545 standard for fire protection of railway vehicles, according to which limiting oxygen index (LOI), smoke density, and conventional index of toxicity (CIT) values under HL3 hazard levels have to be min 32%, max 300, and max 1.5, respectively. 15FR-2MH, 15FR-5MH, 15FR-1MH-1ZB, 15FR-1MH-1BOH, and 15FR-1MH-1SIL composites exhibited both the required smoke density, CIT, and LOI values for R22. …”
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“…Immunohistochemistry and immunofluorescence analysis evaluate the release of myeloperoxidase (MPO), neutrophil elastase (NE), and citrullination of histone H3 (CitH3). Beclin-1 and LC3B expressions were determined using western blotting and immunofluorescence. …”
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