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1281por Török, Szilvia, Almási, Nikoletta, Valkusz, Zsuzsanna, Pósa, Anikó, Varga, Csaba, Kupai, Krisztina“…Furthermore, the expression of members of NETs formation: peptidyl arginine deiminase 4 (PAD4), citrullinated histone H3 (citH3), myeloperoxidase (MPO) and inflammatory regulators, such as nuclear transcription factor-kappa B (NF-κB) and high-mobility group box 1 (HMGB1) were reduced in H(2)S treated group compared to TNBS. …”
Publicado 2021
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1282por Amini, Seyed Mohammad, Mohammadi, Elham, Askarian‐Amiri, Shaghayegh, Azizi, Yaser, Shakeri‐Zadeh, Ali, Neshastehriz, Ali“…Based on Raman and FTIR spectroscopy analysis, chemical binding of API on the surface of Api@AuNPs through hydroxyl and carbonyl functional groups was found to be the main reason for the stability of the Api@AuNPs in comparison with citrate‐coated gold nanoparticles (Cit@AuNPs). The synthesized Api@AuNPs do not cause major toxic effects up to 128 ppm. …”
Publicado 2021
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1283por Cedervall, J., Herre, M., Dragomir, A., Rabelo-Melo, F., Svensson, A., Thålin, C., Rosell, A., Hjalmar, V., Wallén, H., Lindman, H., Pejler, G., Hagström, E., Hultström, M., Larsson, A., Olsson, AK.“…Mice with mammary carcinoma (MMTV-PyMT) had increased plasma levels of NETs measured as H3Cit-DNA complexes, paralleled with elevated coagulation, compared to healthy littermates. …”
Publicado 2022
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1284por Schuster, Sabine, Juhász, Éva, Halmos, Gábor, Neundorf, Ines, Gennari, Cesare, Mező, Gábor“…Considering that the selective release of drugs in cancer cells is of high relevance, we were encouraged to develop cleavable, self-immolative GnRH-III-drug conjugates which consist of a p-aminobenzyloxycarbonlyl (PABC) spacer between a cathepsin B-cleavable dipeptide (Val-Ala, Val-Cit) and the classical anticancer drugs daunorubicin (Dau) and paclitaxel (PTX). …”
Publicado 2022
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1285por Peacock, S., Briggs, D., Barnardo, M., Battle, R., Brookes, P., Callaghan, C., Clark, B., Collins, C., Day, S., Diaz Burlinson, N., Dunn, P., Fernando, R., Fuggle, S., Harmer, A., Kallon, D., Keegan, D., Key, T., Lawson, E., Lloyd, S., Martin, J., McCaughan, J., Middleton, D., Partheniou, F., Poles, A., Rees, T., Sage, D., Santos‐Nunez, E., Shaw, O., Willicombe, M., Worthington, J.“…Guidelines aimed at improving practice based on these issues are presented, and we expect that following these will allow H&I laboratories to contribute to reducing CIT in deceased donor kidney transplantation.…”
Publicado 2021
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1286por Yang, Xin, Wang, Long, Zeng, Jing, Wu, Anguo, Qin, Mi, Wen, Min, Zhang, Ting, Chen, Wang, Mei, Qibing, Qin, Dalian, Yang, Jing, Jiang, Yu, Wu, Jianming“…Until now, there are still no satisfactory medications to treat chemotherapy and radiation-induced thrombocytopenia (CIT and RIT, respectively). Caulis Polygoni Multiflori (CPM), one of the most commonly used Chinese herbs, has been well documented to nourish blood for tranquilizing the mind and treating anemia, suggesting its beneficial effect on hematopoiesis. …”
Publicado 2022
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1287“…In addition, citraconlyated LZ (Cit-LZ) showed reduced spheroid penetration as compared to that of LZ, probably owing to a decrease in protein charge. …”
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1288“…The Caregiver Identity Theory (CIT) was used to guide the study exploring participants’ perception of self-identity within their caregiving relationship and self-identity as a male. …”
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1289por Dolan, Stephen K., Wijaya, Andre, Kohlstedt, Michael, Gläser, Lars, Brear, Paul, Silva-Rocha, Rafael, Wittmann, Christoph, Welch, Martin“…Moreover, through structural and kinetic analysis of the 2-methylcitrate synthase (2-MCS; PrpC) and its paralogue citrate (CIT) synthase (GltA), we show how these two crucial enzymatic steps are interconnected in Pa organic acid assimilation. …”
Publicado 2022
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1290por Qiao, Shan, Sun, Quan-ye, Zhou, Peng, Zhang, Shan-chao, Wang, Zhi-hao, Li, Hai-yun, Wang, Ai-hua, Liu, Xue-wu, Xin, Tao“…Moreover, IL-6, IL-8, and TNF-α levels were positively correlated with H3Cit levels. CONCLUSION: We provide evidence that NETs may play a role in anti-NMDAR encephalitis, providing clues for elucidation of the pathogenesis of this disease.…”
Publicado 2022
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1291“…Each group was further divided into two subgroups based on photoinitiator systems – combination of camphorquinone (CQ), Ivocerin, and 2,4,6-trimethylbenzoyl diphenylphosphine oxide (Subgroup CIT) and only CQ (Subgroup C) in the composite. …”
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1292“…Here, we elucidated a shared biochemical function of LACC1 in mice and humans, converting L-citrulline (L-Cit) to L-ornithine (L-Orn) and isocyanic acid (HNCO) and serving as a bridge between proinflammatory nitric oxide synthase (NOS2) and polyamine immunometabolism. …”
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1293por Farshchi, Fatemeh, Saadati, Arezoo, Hasanzadeh, Mohammad, Liu, Yuqian, Seidi, Farzad“…Different types of AgNPs showed different lower limits of quantification (LLOQ). The AgNPs-Cit and AgNPrs could identify acetaldehyde with linear range of 10(−7) to 10 M and an LLOQ of 10(−7) M. …”
Publicado 2023
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1294“…Studies have shown clear progression-free survival (PFS) benefit of these agents, as well as overall survival (OS) benefit in some instances, when compared with chemoimmunotherapy (CIT). Building on these successes, novel–novel combinations, including doublets and triplets, are under development with study designs exploring fixed and depth-of-response-driven durations. …”
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1295por Dinarieva, Tatiana Yu., Klimko, Alena I., Kahnt, Jörg, Cherdyntseva, Tatiana A., Netrusov, Alexander I.“…Downregulated proteins participate in ROS defense (AhpC), citrate and pyruvate consumption (CitE, PflB), oxaloacetate production (AvtA), arginine synthesis (ArgG), amino acid transport (GlnQ), and deoxynucleoside biosynthesis (RtpR). …”
Publicado 2023
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1296“…After treatment with either normothermia (NT) or therapeutic hypothermia (TH), we observed a significantly enhanced expression level of the NETosis marker Citrullinated H3 (Cit-H3), which was significantly more pronounced in animals treated with TH than in those treated with NT. …”
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1297por Jeong, Seongtae, Lee, Bok-Sim, Jung, Seung Eun, Yoon, Yoojin, Song, Byeong-Wook, Kim, Il-Kwon, Choi, Jung-Won, Kim, Sang Woo, Lee, Seahyoung, Lim, Soyeon“…According to our data, citreoviridin (CIT) has both an anti-VC effect and anti-osteoclastic effect in vSMCs and in Raw 264.7 cells, respectively, suggesting its potential as an effective therapeutic agent for both VC and osteoporosis.…”
Publicado 2023
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1298por Verdú-Andrés, S, Amaldi, U, Bonomi, R, Degiovanni, A, Garlasché, M, Garonna, A, Mellace, C, Pearce, P, S. Verdú-Andrés, Wegner, R“…The 19 mm-long cell is foreseen to be excited at 200 Hz by 3 us RF pulses and should reach a 40 MV/m accelerating gradient, which corresponds to a peak surface electric field Es of 260 MV/m. …”
Publicado 2010
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1299por Inkret, Suzana, Ćurlin, Marija, Smokrović, Kristina, Kalčec, Nikolina, Peranić, Nikolina, Maltar-Strmečki, Nadica, Domazet Jurašin, Darija, Dutour Sikirić, Maja“…Motivated by this lack of data in this study we investigated the influence of AgNPs stabilized with citrate (cit-AgNPs), poly(vinylpyrrolidone) (PVP-AgNPs), and sodium bis(2-ethylhexyl) sulfosuccinate (AOT-AgNPs) in the concentration range 5–25 mg dm(−3) on the precipitation of CaPs. …”
Publicado 2023
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1300por Jawaid, Talha, Alaseem, Ali Mohammed, Khan, Mohammed Moizuddin, Mukhtar, Beenish, Kamal, Mehnaz, Anwer, Razique, Ahmed, Saif, Alam, Aftab“…The percentage % of entrapment efficiency (%EE) of nanoemulsions loaded with CIT was very high at the beginning of the study, at 95.5 ± 4.775%. …”
Publicado 2023
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