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  1. 1401
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    High Prevalence of Antibiotic-Resistant Mycoplasma genitalium in Nongonococcal Urethritis: The Need for Routine Testing and the Inadequacy of Current Treatment Options
  2. 1402
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    Whole-Genome Sequencing Shows That Patient-to-Patient Transmission Rarely Accounts for Acquisition of Staphylococcus aureus in an Intensive Care Unit
  3. 1403
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    Statins and the Risk of Herpes Zoster: A Population-Based Cohort Study
  4. 1404
    “…RESULTS: In this study, the genes closely related to itaconic acid production, including cadA, mfsA, mttA, ATEG_09969, gpdA, ATEG_01954, acoA, mt-pfkA and citA, were identified and overexpressed in an industrial A. terreus strain respectively. …”
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    Improving itaconic acid production through genetic engineering of an industrial Aspergillus terreus strain
  5. 1405
    “…Motor and exploratory behaviors were assessed for 30 min in an open field prior to administration of [(123)I]FP-CIT. Dopamine transporter binding was measured with small animal single-photon emission computed tomography (SPECT) 2 h after radioligand administration for 60 min. …”
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    Relationship between L-DOPA-induced reduction in motor and exploratory activity and degree of DAT binding in the rat
  6. 1406
    “…ESBL genes (bla (SHV), bla (TEM), bla (OXA), and bla (CTX-M)) and ampC genes (bla (MOX,) bla (FOX,) bla (MIR(ACT-1),) bla (DHA,) bla (CIT) and bla (ACC)) were subsequently detected among the 15 isolates. …”
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    Antimicrobial Resistance of Shigella flexneri Serotype 1b Isolates in China
  7. 1407
    “…Fourteen heavy alcohol drinking smokers (n=6) and nonsmokers (n=8) and 14 age-matched control smokers (n=6) and nonsmokers (n=8) were imaged with [(123)]β-CIT SPECT. Alcohol drinking smokers and nonsmokers consumed 134.3±100.3 and 196.5±139.9 drinks, respectively over the previous month and were imaged during acute withdrawal, e.g., within 5 days of their last drink. …”
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    DOPAMINE AND SEROTONIN TRANSPORTER AVAILABILITY DURING ACUTE ALCOHOL WITHDRAWAL: EFFECTS OF COMORBID TOBACCO SMOKING
  8. 1408
    “…This plasmid is an IncA/C incompatibility type composed of 155 predicted coding sequences and shares homology with plasmids of E. coli pNDM-1_Dok01, Klebsiella pNDM-KN, and Citrobacter pNDM-CIT. In pNDM-SAL, gene cluster containing bla(NDM-1) was located between IS26 and IS4321 elements. …”
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    Attributes of carbapenemase encoding conjugative plasmid pNDM-SAL from an extensively drug-resistant Salmonella enterica Serovar Senftenberg
  9. 1409
    “…RESULTS: A serum metabolite signature of impaired urea cycle function (i.e. higher [ARG]:[ORN + CIT]) was observed in human (CTRL: 0.45 ± 0.03, AD: 1.29 ± 0.04; p < 0.001) and mouse (AAV-miR-NC: 0.97 ± 0.13, AAV-miR-GR: 2.20 ± 0.19; p < 0.001) GC/GR loss-of-function, with similar patterns also observed in liver. …”
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    Molecular regulation of urea cycle function by the liver glucocorticoid receptor
  10. 1410
    “…The most prevalent genes responsible for ESBL or pAmpC activity belonged to the CTX-M-9 (110/342, 31.2%), CTX-M-1 (102/342, 29.8%), and CIT (118/342, 34.5%) groups. To our knowledge, this is the first report of the high occurrence of pAmpC (37.1%) in animal-based food in Vietnam. …”
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    Dissemination of Extended-Spectrum β-Lactamase- and AmpC β-Lactamase-Producing Escherichia coli within the Food Distribution System of Ho Chi Minh City, Vietnam
  11. 1411
    “…Brain metabolism ([(18)F]FDG and [(15)O]H(2)O), presynaptic ([(18)F]fluorodopa, [(11)C]β-CIT and [(11)C]DTBZ) and postsynaptic ([(11)C]SCH22390, [(11)C]FLB457 and [(11)C]raclopride) dopaminergic function, phosphodiesterases ([(18)F]JNJ42259152, [(18)F]MNI-659 and [(11)C]IMA107), and adenosine ([(18)F]CPFPX), cannabinoid ([(18)F]MK-9470), opioid ([(11)C]diprenorphine) and GABA ([(11)C]flumazenil) receptors were evaluated as potential biomarkers for monitoring disease progression and for assessing the development and efficacy of novel disease-modifying drugs in premanifest HD carriers and HD patients. …”
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    Current status of PET imaging in Huntington’s disease
  12. 1412
    “…Regression analysis demonstrated that six of them – Arg, Pro, C10:1, Arg/Orn, Cit/Arg, and C5-OH/C0 – could be used to diagnose LC with a sensitivity of 91.3% and a specificity of 92.7%. …”
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    Tandem mass spectrometry-based newborn screening strategy could be used to facilitate rapid and sensitive lung cancer diagnosis
  13. 1413
    “…The proposed method was evaluated using an antibody-fluorophore conjugate (AFC) as an ADC surrogate to brentuximab vedotin and its associated parent maleimide-val-cit-DSEA payload and the derived N-acetylcysteine adduct formed during the conjugation process. …”
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    A sensitive multidimensional method for the detection, characterization, and quantification of trace free drug species in antibody-drug conjugate samples using mass spectral detection
  14. 1414
    “…Three patients also performed a single-photon computed tomography (SPECT) with [(123)I]N-ω-fluoropropyl-2β-carbomethoxy-3β-(4-iodophenyl)nortropane (FP-CIT) to assess striatal dopaminergic innervation. …”
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    Striatal Dopaminergic Innervation Regulates Subthalamic Beta-Oscillations and Cortical-Subcortical Coupling during Movements: Preliminary Evidence in Subjects with Parkinson’s Disease
  15. 1415
    “…After 6, 12, 24, 48 and 120 hr aspartate (Asp), glutamate (Glu), asparagine (Asn), serine (Ser), glutamine (Gln), histidine (His), glycine (Gly), threonine (Thr), citrulline (Cit), arginine (Arg), alanine (Ala), taurine (Tau), γ‐aminobutyrate (GABA), tyrosine (Tyr), S‐adenosylhomocysteine (SAH), l‐cystathionine (l‐Cystat), valine (Val), methionine (Met), tryptophane (Trp), phenylalanine (Phe), isoleucine (Ile), leucine (Leu), ornithine (Orn), lysine (Lys), plus N‐acetylaspartate (NAA) were determined in whole brain extracts (n = 6 rats at each time for both TBI levels). …”
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    Severity of experimental traumatic brain injury modulates changes in concentrations of cerebral free amino acids
  16. 1416
    “…RESULTS: We quantified cellular uptake of 75 nm diameter citrate stabilized silver NPs (Ag 75 Cit) into an individual human macrophage derived from monocytic THP-1 cells using a FIB/SEM slice and view approach. …”
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    Quantification of silver nanoparticle uptake and distribution within individual human macrophages by FIB/SEM slice and view
  17. 1417
    “…CAGE revealed that 4 genes associated with glucose metabolism (GPI, G6PD, PKM2, and GAPDH) and 5 associated with the cell cycle (ANLN, PTTG1, CIT, KPNA2, and CDC25A) were positively correlated with SUV(max), although expression levels were lower in EGFR-mutated than in wild-type tumors. …”
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    Correlation of EGFR or KRAS mutation status with (18)F-FDG uptake on PET-CT scan in lung adenocarcinoma
  18. 1418
    “…FBR is an effective and tolerable CIT regimen for patients with relapsed CLL.…”
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    A phase I-II trial of fludarabine, bendamustine and rituximab (FBR) in previously treated patients with CLL
  19. 1419
    “…Striatal DAT and D2/3 receptor binding were assessed using [(123)I]FP-CIT and [(123)I]IBZM SPECT, respectively. The ratio of specific striatal to non-specific binding (binding potential; BP(ND)) was the outcome measure. …”
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    The relationship between the dopaminergic system and depressive symptoms in cervical dystonia
  20. 1420
    “…BACKGROUND: The differential diagnosis between patients with essential tremor (ET) and those with Parkinson’s disease (PD) whose main manifestation is tremor may be difficult unless using complex neuroimaging techniques such as (123)I-FP-CIT SPECT. We considered that using smartphone’s accelerometer to stablish a diagnostic test based on time-frequency differences between PD an ET could support the clinical diagnosis. …”
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    Differential diagnosis between Parkinson's disease and essential tremor using the smartphone's accelerometer
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