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1501por Youn, Jinyoung, Lee, Sang-Bin, Lee, Hyo Sang, Yang, Hyun Ok, Park, Jinse, Kim, Ji Sun, Oh, Eungseok, Park, Suyeon, Jang, Wooyoung“…Furthermore, LC3B was significantly correlated with the asymmetry index in the caudate and putamen, as estimated by a semi-quantitative analysis of [(18)F] N-(3-fluoropropyl)-2β-carbon ethoxy-3β-(4-iodophenyl) nortropane (FP-CIT) positron emission tomography (PET). CSF levels of LC3B represented a potential diagnostic and prognostic biomarker of early-stage PD in patients. …”
Publicado 2018
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1502por Di Castro, Viviane Cruvinel, Hernandes, Janete Capel, Mendonça, Mauro Elias, Porto, Celmo Celeno“…The instruments are Satisfaction With Life Scale (SWLS), Scale of Positive and Negative Experience (SPANE), Positive Thinking Scale (PTS), Flourishing Scale (FS), Comprehensive Inventory of Thriving (CIT), and Brief Inventory of Thriving (BIT). The studies will come from Scientific Electronic Library Online (SciELO), Biblioteca Virtual em Saúde (BVS), Portal da Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES), MEDLINE, Embase, Web of Science, and Global Index Medicus databases. …”
Publicado 2018
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1503por Murthy, Pranav, Singhi, Aatur D., Ross, Mark A., Loughran, Patricia, Paragomi, Pedram, Papachristou, Georgios I., Whitcomb, David C., Zureikat, Amer H., Lotze, Michael T., Zeh III, Herbert J., Boone, Brian A.“…Biomarkers of NET formation, including cell-free DNA, citrullinated histone H3 (CitH3), and MPO-DNA conjugates were measured in murine serum and correlative human patient serum samples. …”
Publicado 2019
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1504Cold-inducible RNA-binding Protein Induces Neutrophil Extracellular Traps in the Lungs during Sepsispor Ode, Yasumasa, Aziz, Monowar, Jin, Hui, Arif, Adnan, Nicastro, Jonathan G., Wang, Ping“…After 20 h of CLP induction, NETs in the lungs of WT and CIRP(−/−) mice were quantified by flow cytometry by staining the single cell suspensions with MPO and CitH3 Abs. PAD4 expression in the lungs of WT and CIRP(−/−) mice after sepsis was assessed by Western blotting. …”
Publicado 2019
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1505“…Materials and methods: In the present study, we reanalyzed data from four public datasets (the Cancer Genome Atlas for investigation; and CIT, GSE5287, and GSE31684 for validation) to examine the prognostic significance of CD3D, CD4, CD8A, CD3D/CD4 and CD3D/CD8A in MIBC. …”
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1506“…Three strains were AmpC positive, all of which harbored bla(CMY-2) and two contained bla(CIT). Of the 19 Shigella isolates 5 (26.3%), 2 (10.5%), and 1 (5.2%) were phenotypically resistant to nalidixic acid, ciprofloxacin, and norfloxacin, respectively. …”
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1507por Yao, Jiqiang, Chen, Yunyun, Nguyen, Duy T., Thompson, Zachary J., Eroshkin, Alexey M., Nerlakanti, Niveditha, Patel, Ami K., Agarwal, Neha, Teer, Jamie K., Dhillon, Jasreman, Coppola, Domenico, Zhang, Jingsong, Perera, Ranjan, Kim, Youngchul, Mahajan, Kiran“…The expression of a two-gene set, CIT and HSPB8 with an overall balanced accuracy of 98.8% and a threshold value of 0.2347, was sufficient to classify metastasis. …”
Publicado 2019
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1508por Knecht, Henrik, Reigl, Tomas, Kotrová, Michaela, Appelt, Franziska, Stewart, Peter, Bystry, Vojtech, Krejci, Adam, Grioni, Andrea, Pal, Karol, Stranska, Kamila, Plevova, Karla, Rijntjes, Jos, Songia, Simona, Svatoň, Michael, Froňková, Eva, Bartram, Jack, Scheijen, Blanca, Herrmann, Dietrich, García-Sanz, Ramón, Hancock, Jeremy, Moppett, John, van Dongen, Jacques J. M., Cazzaniga, Giovanni, Davi, Frédéric, Groenen, Patricia J. T. A., Hummel, Michael, Macintyre, Elizabeth A., Stamatopoulos, Kostas, Trka, Jan, Langerak, Anton W., Gonzalez, David, Pott, Christiane, Brüggemann, Monika, Darzentas, Nikos“…First, a central polytarget QC (cPT-QC) is used to monitor the primer performance of each of the EuroClonality multiplex NGS assays; second, a standardised human cell line-based DNA control is spiked into each patient DNA sample to work as a central in-tube QC and calibrator for MRD quantification (cIT-QC). Having integrated those two reference standards in the ARResT/Interrogate bioinformatic platform, EuroClonality-NGS provides a complete protocol for standardised IG/TR gene rearrangement analysis by NGS with high reproducibility, accuracy and precision for valid marker identification and quantification in diagnostics of lymphoid malignancies.…”
Publicado 2019
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1509“…Also, BRCA carrying one of four gene mutations had higher expression of LINC01614 including AOAH, CIT, HER2 and ODZ1. Higher expression of LINC01614 was positively correlated with several gene sets including TGF-β1 response, CDH1 signals and cell adhesion pathways. …”
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1510por Li, Hongliang, Hirano, Shigeki, Furukawa, Shogo, Nakano, Yoshikazu, Kojima, Kazuho, Ishikawa, Ai, Tai, Hong, Horikoshi, Takuro, Iimori, Takashi, Uno, Takashi, Matsuda, Hiroshi, Kuwabara, Satoshi“…All subjects were scanned with both T1-weighted magnetic resonance imaging (MRI) and (123)I-FP-CIT single-photon emission computed tomography (SPECT) images. …”
Publicado 2020
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1511por Dai, James Y., Wang, Xiaoyu, Wang, Bo, Sun, Wei, Jordahl, Kristina M., Kolb, Suzanne, Nyame, Yaw A., Wright, Jonathan L., Ostrander, Elaine A., Feng, Ziding, Stanford, Janet L.“…The role of DNA methylation in eQTL regulation of gene expression was investigated by data triangulation using several causal inference approaches, including a proposed adaptation of the Causal Inference Test (CIT) for causal direction. Comparing eQTLs between tumors and benign samples, we show that 98 of the 147 risk SNPs were identified as eQTLs in the tumor-adjacent benign samples, and almost all 34 eQTL identified in tumor sets were also eQTLs in the benign samples. …”
Publicado 2020
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1512“…METHODS: We collected data from 262 respondents with a critical incident technique (CIT) questionnaire. We analyzed the responses with applied thematic analysis with ATLAS.ti (ATLAS.ti Scientific Software Development GmbH) software. …”
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1513por Lasch, Manuel, Kumaraswami, Konda, Nasiscionyte, Simona, Kircher, Susanna, van den Heuvel, Dominic, Meister, Sarah, Ishikawa-Ankerhold, Hellen, Deindl, Elisabeth“…Moreover, RNase A treatment was associated with a significant reduction in leukocyte infiltration as shown by CD45(+) (pan-leukocyte marker), Ly6G(+) or MPO(+) (neutrophils), MPO(+)/CitH(3)(+) [neutrophil extracellular traps (NETs)], and CD68(+) (macrophages) staining. …”
Publicado 2020
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1514por Jia, Jinchao, Wang, Mengyan, Ma, Yuning, Teng, Jialin, Shi, Hui, Liu, Honglei, Sun, Yue, Su, Yutong, Meng, Jianfen, Chi, Huihui, Chen, Xia, Cheng, Xiaobing, Ye, Junna, Liu, Tingting, Wang, Zhihong, Wan, Liyan, Zhou, Zhuochao, Wang, Fan, Yang, Chengde, Hu, Qiongyi“…Plasma samples were used to measure cell-free DNA, NE-DNA, MPO-DNA, and citH3-DNA complexes from training and validation sets. …”
Publicado 2020
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1515por Nowak, Katarzyna, Berger, Joel, Panikowski, Amy, Reid, Donald G., Jacob, Aerin L., Newman, Greg, Young, Nicholas E., Beckmann, Jon P., Richards, Shane A.“…Leveraging the community science portals iNaturalist and CitSci, in less than a year we amassed a database of almost seven hundred unique photographs spanning some 4,500 km between latitudes 37.6°N and 61.1°N from 0 to 4,333 m elevation. …”
Publicado 2020
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1516por Chen, Rao, Wang, Haifeng, Song, Lei, Hou, Jianfei, Peng, Jiawei, Dai, Helong, Peng, Longkai“…Binary logistic regression analysis showed correlations between the incidence of DGF and cold ischemic time (CIT), warm ischemic time (WIT), terminal serum creatine (Scr) concentration, duration of pretransplant dialysis, primary cause of donor death, and usage of LifePort. …”
Publicado 2020
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1517por Sonaimuthu, P., Senkevitch, E., Haskins, N., Uapinyoying, P., McNutt, M., Morizono, H., Tuchman, M., Caldovic, L.“…The NAGS knockout (Nags(−/−)) mouse is an animal model of inducible hyperammonemia, which develops hyperammonemia without N-carbamylglutamate and L-citrulline supplementation (NCG + Cit). We used adeno associated virus (AAV) based gene transfer to correct NAGS deficiency in the Nags(−/−) mice, established the dose of the vector needed to rescue Nags(−/−) mice from hyperammonemia and measured expression levels of Nags mRNA and NAGS protein in the livers of rescued animals. …”
Publicado 2021
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1518por Tessier‐Cloutier, Basile, Twa, David DW, Marzban, Mahsa, Kalina, Jennifer, Chun, Hye‐Jung E, Pavey, Nils, Tanweer, Zaidi, Katz, Ruth L, Lum, Julian J, Salina, Davide“…IHC analysis showed loss of E‐cadherin in viable tumour cells in areas with high TINs, and neutrophil activation was associated with elastase and citrullinated histone H3 expression (cit‐H3). In the TCGA cohort, neutrophilic markers were also associated with worse survival (p < 0.0001). …”
Publicado 2021
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1519“…The sorbents tested in the study included: unmodified chitosan (CHs), chitosan ionically cross-linked with sodium citrate (CHs-CIT), and chitosan covalently cross-linked with epichlorohydrin (CHs-ECH). …”
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1520por Saisorn, Wilasinee, Saithong, Supichcha, Phuengmaung, Pornpimol, Udompornpitak, Kanyarat, Bhunyakarnjanarat, Thansita, Visitchanakun, Peerapat, Chareonsappakit, Awirut, Pisitkun, Prapaporn, Chiewchengchol, Direkrit, Leelahavanichkul, Asada“…At 24 h post-renal I/R injury, NETs in peripheral blood neutrophils and in kidneys were detected using myeloperoxidase (MPO), neutrophil elastase (NE) and citrullinated histone H3 (CitH3), as well as kidney apoptosis (activating caspase-3), which were prominent in Fcgr2b-/- mice more compared to wild-type (WT). …”
Publicado 2021
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